6/20/12 20:38  | 6/19/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 157 | 12.20 | 0 | 13 |  | 10 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/20/12 20:38  | 6/19/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -410 | 31.96 | 0 | -13 | -56 | 10 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/12/12 17:56  | 6/11/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Beck John W | CA | O | SVP,Fina | M.d | 400 | 14.26 | 0 | 28 |  | 4 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/12/12 17:56  | 6/11/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Beck John W | CA | O | SVP,Fina | S.d | -897 | 31.97 | 0 | -28 | -86 | 4 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
5/29/12 18:50  | 5/29/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 0 | 5 | 101 | 10 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
5/29/12 18:50  | 5/29/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -159 | 31.89 | 0 | -5 | -33 | 10 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/30/12 19:34  | 4/30/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 0 | 5 | 106 | 10 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/30/12 19:34  | 4/30/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -159 | 31.82 | 0 | -5 | -34 | 10 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/26/12 19:17  | 4/25/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | M.d | 28 | 2.76 | 0 | 10 | 999% | 10 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/26/12 19:17  | 4/25/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | S.d | -316 | 31.64 | 0 | -10 | -49 | 10 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/29/12 19:32  | 3/28/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 0 | 5 | 106 | 10 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/29/12 19:32  | 3/28/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -113 | 22.65 | 0 | -5 | -34 | 10 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
2/29/12 19:40  | 2/28/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 7 | 5 | 106 | 10 | D | 47 | -20 | 43 | 24 | 37 | 8 | 10 | 3 | -1 | -5 |  |  |  |  | 
2/29/12 19:40  | 2/28/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -105 | 20.99 | 7 | -5 | -34 | 10 | D | 47 | -20 | 43 | 24 | 37 | 8 | 10 | 3 | -1 | -5 |  |  |  |  | 
2/3/12 18:05  | 2/1/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Tang Kevin C | CA | DT |  | P | 7,250 | 17.00 | 6 | 426 | 13 | 3,816 | I | 30 | -29 | -12 | 0 | 4 | 23 | 8 | 4 | 4 | -2 | 7 |  |  |  | 
2/3/12 17:52  | 2/1/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker Brothers Life Sciences Capital (Gp), LLC | NY | DT |  | P | 14,906 | 17.00 | 6 | 877 | 22 | 4,922 | I | 30 | -29 | -12 | 0 | 4 | 23 | 8 | 4 | 4 | -2 | 7 |  |  |  | 
2/3/12 17:51  | 2/1/12  | RDEA | Health | Drug | Pharmaceutical Preparations | 14159 Capital (Gp), LLC | NY | DT |  | P | 394 | 17.00 | 6 | 23 | 25 | 116 | I | 30 | -29 | -12 | 0 | 4 | 23 | 8 | 4 | 4 | -2 | 7 |  |  |  | 
1/31/12 21:25  | 1/30/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 3 | 5 | 106 | 10 | D | 24 | -34 | -23 | -16 | -3 | 17 | 6 | 0 | -2 | 11 | 17 |  |  |  | 
1/31/12 21:25  | 1/30/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -90 | 18.01 | 3 | -5 | -34 | 10 | D | 24 | -34 | -23 | -16 | -3 | 17 | 6 | 0 | -2 | 11 | 17 |  |  |  | 
1/6/12 19:48  | 1/6/12  | RDEA | Health | Drug | Pharmaceutical Preparations | Davis Stephen | CA | O | EVP,COO | S | -11 | 15.91 | 3 | -1 | -4 | 16 | D | 16 | -38 | -38 | 5 | -11 | -5 | -8 | -4 | 0 | -1 | 29 |  |  |  | 
12/29/11 21:46  | 12/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 2 | 5 | 106 | 10 | D | 20 | -37 | -33 | 8 | -11 | -13 | -10 | -5 | -1 | -5 | 6 |  |  |  | 
12/29/11 21:46  | 12/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -85 | 16.97 | 2 | -5 | -34 | 10 | D | 20 | -37 | -33 | 8 | -11 | -13 | -10 | -5 | -1 | -5 | 6 |  |  |  | 
11/29/11 21:13  | 11/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 2 | 5 | 106 | 10 | D | 21 | -22 | -30 | 14 | 6 | -8 | -7 | -4 | 7 | 15 | -3 | 22 |  |  | 
11/29/11 21:13  | 11/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -88 | 17.67 | 2 | -5 | -34 | 10 | D | 21 | -22 | -30 | 14 | 6 | -8 | -7 | -4 | 7 | 15 | -3 | 22 |  |  | 
11/17/11 19:28  | 11/15/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Davis Stephen | CA | O | EVP,COO | S | -8 | 18.86 | 2 | 0 | -2 | 17 | D | 45 | -16 | -24 | 36 | 19 | -13 | -1 | -3 | -1 | -7 | 2 | 3 |  |  | 
10/28/11 21:43  | 10/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 2 | 5 | 114 | 9 | D | 53 | 1 | -24 | -8 | 32 | 42 | 24 | 11 | -5 | -5 | -16 | -13 |  |  | 
10/28/11 21:43  | 10/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -106 | 21.27 | 2 | -5 | -35 | 9 | D | 53 | 1 | -24 | -8 | 32 | 42 | 24 | 11 | -5 | -5 | -16 | -13 |  |  | 
10/7/11 21:12  | 10/6/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Davis Stephen | CA | O | EVP,COO | S | -11 | 15.43 | 2 | -1 | -4 | 17 | D | -9 | -33 | -45 | -39 | 11 | -3 | -6 | 10 | 5 | 12 | 23 | 2 |  |  | 
9/30/11 20:28  | 9/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 2 | 5 | 114 | 9 | D | -13 | -31 | -45 | -38 | 16 | 4 | -4 | -1 | -8 | 1 | 34 | 9 |  |  | 
9/30/11 20:28  | 9/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -81 | 16.28 | 2 | -5 | -35 | 9 | D | -13 | -31 | -45 | -38 | 16 | 4 | -4 | -1 | -8 | 1 | 34 | 9 |  |  | 
8/30/11 21:11  | 8/29/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 3 | 5 | 114 | 9 | D | -14 | -23 | -41 | -39 | -36 | -10 | 12 | 4 | 2 | -3 | -1 | 10 | 36 |  | 
8/30/11 21:11  | 8/29/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -76 | 15.13 | 3 | -5 | -35 | 9 | D | -14 | -23 | -41 | -39 | -36 | -10 | 12 | 4 | 2 | -3 | -1 | 10 | 36 |  | 
8/2/11 21:18  | 8/1/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Johnson Craig A | CA | D |  | M.d | 12 | 12.16 | 2 | 1 |  | 0 | D | 20 | 15 | -12 | -15 | -5 | -9 | -6 | 1 | -2 | -22 | -25 | -3 | -15 |  | 
8/2/11 21:18  | 8/1/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Johnson Craig A | CA | D |  | S.d | -23 | 23.16 | 2 | -1 | -100 | 0 | D | 20 | 15 | -12 | -15 | -5 | -9 | -6 | 1 | -2 | -22 | -25 | -3 | -15 |  | 
7/29/11 20:47  | 7/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 2 | 5 | 114 | 9 | D | 21 | 20 | -16 | -17 | -3 | -10 | -3 | -4 | 0 | -14 | -36 | -17 | -20 |  | 
7/29/11 20:47  | 7/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -118 | 23.56 | 2 | -5 | -35 | 9 | D | 21 | 20 | -16 | -17 | -3 | -10 | -3 | -4 | 0 | -14 | -36 | -17 | -20 |  | 
7/26/11 21:34  | 7/25/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Beck John W | CA | O | SVP,Fina | M.d | 228 | 14.26 | 2 | 16 |  | 4 | D | 26 | 24 | -7 | -12 | 4 | -4 | -2 | 0 | -3 | -2 | -39 | -28 | -26 |  | 
7/26/11 21:34  | 7/25/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Beck John W | CA | O | SVP,Fina | S.d | -391 | 24.46 | 2 | -16 | -78 | 4 | D | 26 | 24 | -7 | -12 | 4 | -4 | -2 | 0 | -3 | -2 | -39 | -28 | -26 |  | 
7/8/11 21:03  | 7/6/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Davis Stephen | CA | O | EVP,COO | S | -18 | 25.65 | 3 | -1 | -4 | 19 | D | 42 | 30 | 0 | -10 | 12 | 8 | 3 | -2 | -3 | -4 | -30 | -41 | -38 |  | 
7/5/11 21:12  | 7/1/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Johnson Craig A | CA | D |  | M.d | 24 | 12.16 | 3 | 2 |  | 0 | D | 57 | 36 | 2 | -9 | 7 | 13 | 7 | 3 | -1 | -2 | -14 | -38 | -33 |  | 
7/5/11 21:12  | 7/1/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Johnson Craig A | CA | D |  | S.d | -52 | 26.24 | 3 | -2 | -100 | 0 | D | 57 | 36 | 2 | -9 | 7 | 13 | 7 | 3 | -1 | -2 | -14 | -38 | -33 |  | 
6/29/11 21:08  | 6/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 3 | 5 | 114 | 9 | D | 62 | 23 | -3 | -8 | 4 | 7 | 5 | 3 | 0 | 0 | -8 | -34 | -33 |  | 
6/29/11 21:08  | 6/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -127 | 25.37 | 3 | -5 | -35 | 9 | D | 62 | 23 | -3 | -8 | 4 | 7 | 5 | 3 | 0 | 0 | -8 | -34 | -33 |  | 
6/6/11 21:14  | 6/3/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | M.d | 8 | 2.76 | 5 | 3 | 40 | 10 | D | 56 | 5 | 9 | -9 | -13 | -8 | 8 | -3 | 1 | -3 | 7 | -35 | -20 |  | 
6/6/11 21:14  | 6/3/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | S.d | -73 | 24.25 | 5 | -3 | -22 | 10 | D | 56 | 5 | 9 | -9 | -13 | -8 | 8 | -3 | 1 | -3 | 7 | -35 | -20 |  | 
6/3/11 21:05  | 6/2/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Poyhonen John | CA | D |  | M.dm | 32 | 5.85 | 5 | 6 |  | 0 | D | 56 | 0 | 11 | -8 | -11 | -8 | 6 | 0 | -1 | -2 | 9 | -32 | -22 |  | 
6/3/11 21:05  | 6/2/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Poyhonen John | CA | D |  | S.dm | -136 | 24.68 | 5 | -6 | -100 | 0 | D | 56 | 0 | 11 | -8 | -11 | -8 | 6 | 0 | -1 | -2 | 9 | -32 | -22 |  | 
6/1/11 20:52  | 5/31/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 5 | 5 | 114 | 9 | D | 56 | 5 | 12 | -4 | -13 | -8 | 1 | 8 | 0 | -2 | 3 | -37 | -29 |  | 
6/1/11 20:52  | 5/31/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -124 | 24.83 | 5 | -5 | -35 | 9 | D | 56 | 5 | 12 | -4 | -13 | -8 | 1 | 8 | 0 | -2 | 3 | -37 | -29 |  | 
5/18/11 21:07  | 5/16/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Davis Stephen | CA | O | EVP,COO | S | -9 | 25.52 | 4 | 0 | -2 | 20 | D | 54 | 3 | 11 | -7 | -15 | -12 | -10 | -8 | -1 | -10 | -4 | -40 | -24 |  | 
5/18/11 21:06  | 5/16/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Beck John W | CA | O | SVP,Fina | M.dm | 63 | 25.32 | 4 | 3 | 131 | 4 | D | 54 | 3 | 11 | -7 | -15 | -12 | -10 | -8 | -1 | -10 | -4 | -40 | -24 |  | 
5/11/11 21:29  | 5/9/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | M.d | 78 | 3.90 | 3 | 20 | 47 | 62 | D | 87 | 14 | 13 | 1 | -3 | -1 | -4 | -1 | -1 | -9 | -12 | -36 | -29 |  | 
5/11/11 21:29  | 5/9/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | S.d | -544 | 27.20 | 3 | -20 | -24 | 62 | D | 87 | 14 | 13 | 1 | -3 | -1 | -4 | -1 | -1 | -9 | -12 | -36 | -29 |  | 
4/29/11 21:49  | 4/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 2 | 5 | 124 | 9 | D | 100 | 8 | 34 | 1 | 2 | 0 | -1 | 2 | -3 | -4 | -13 | -18 | -31 |  | 
4/29/11 21:49  | 4/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -139 | 27.80 | 2 | -5 | -36 | 9 | D | 100 | 8 | 34 | 1 | 2 | 0 | -1 | 2 | -3 | -4 | -13 | -18 | -31 |  | 
4/8/11 21:25  | 4/8/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Davis Stephen | CA | O | EVP,COO | S | -85 | 28.20 | 3 | -3 | -13 | 20 | D | 207 | 28 | 21 | 9 | 5 | 0 | 1 | -1 | -1 | 0 | -3 | -7 | -43 |  | 
3/29/11 21:07  | 3/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 3 | 5 | 124 | 9 | D | 146 | 50 | 18 | 4 | 4 | 3 | -1 | 1 | 4 | 2 | 0 | -11 | -43 |  | 
3/29/11 21:07  | 3/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -139 | 27.76 | 3 | -5 | -36 | 9 | D | 146 | 50 | 18 | 4 | 4 | 3 | -1 | 1 | 4 | 2 | 0 | -11 | -43 |  | 
3/1/11 21:20  | 2/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 3 | 5 | 124 | 9 | D | 124 | 83 | 32 | 17 | -5 | -1 | -4 | 1 | 0 | 2 | 8 | -5 | -42 | -18 | 
3/1/11 21:20  | 2/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -132 | 26.50 | 3 | -5 | -36 | 9 | D | 124 | 83 | 32 | 17 | -5 | -1 | -4 | 1 | 0 | 2 | 8 | -5 | -42 | -18 | 
2/16/11 21:07  | 2/15/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Beck John W | CA | O | SVP,Fina | M.d | 200 | 26.61 | 5 | 8 |  | 4 | D | 93 | 82 | 34 | 19 | 3 | -7 | -1 | -1 | 2 | -5 | 1 | -11 | -47 | -32 | 
2/9/11 21:28  | 2/7/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | M.dm | 137 | 3.90 | 5 | 35 | 129 | 62 | D | 108 | 84 | 34 | 12 | 1 | 0 | -2 | 0 | 3 | 1 | -1 | 3 | -34 | -27 | 
2/9/11 21:28  | 2/7/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | S.d | -535 | 26.77 | 5 | -20 | -24 | 62 | D | 108 | 84 | 34 | 12 | 1 | 0 | -2 | 0 | 3 | 1 | -1 | 3 | -34 | -27 | 
1/28/11 21:29  | 1/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 5 | 5 | 124 | 9 | D | 135 | 92 | 43 | 32 | 12 | 7 | 1 | 6 | -3 | -2 | -3 | 3 | -14 | -31 | 
1/28/11 21:29  | 1/28/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -137 | 27.38 | 5 | -5 | -36 | 9 | D | 135 | 92 | 43 | 32 | 12 | 7 | 1 | 6 | -3 | -2 | -3 | 3 | -14 | -31 | 
1/24/11 17:15  | 1/20/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Tang Kevin C | CA | DT |  | P | 5,512 | 26.00 | 4 | 212 | 7 | 3,389 | I | 117 | 82 | 36 | 16 | 18 | -1 | -12 | -6 | 7 | 5 | 4 | 6 | -5 | -35 | 
1/24/11 16:08  | 1/20/11  | RDEA | Health | Drug | Pharmaceutical Preparations | 14159 Capital (Gp), LLC | NY | DT |  | P | 255 | 26.00 | 4 | 10 | 12 | 93 | I | 117 | 82 | 36 | 16 | 18 | -1 | -12 | -6 | 7 | 5 | 4 | 6 | -5 | -35 | 
1/24/11 16:06  | 1/20/11  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker Brothers Life Sciences Capital (Gp), LLC | NY | DT |  | P | 9,245 | 26.00 | 4 | 356 | 10 | 4,036 | I | 117 | 82 | 36 | 16 | 18 | -1 | -12 | -6 | 7 | 5 | 4 | 6 | -5 | -35 | 
12/30/10 20:10  | 12/28/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.dm | 39 | 3.90 | 2 | 10 |  | 9 | D | 138 | 89 | 31 | 17 | 20 | 24 | 6 | 4 | -1 | -1 | 4 | 11 | -3 | -34 | 
12/30/10 20:10  | 12/28/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -133 | 26.62 | 2 | -5 | -36 | 9 | D | 138 | 89 | 31 | 17 | 20 | 24 | 6 | 4 | -1 | -1 | 4 | 11 | -3 | -34 | 
12/10/10 21:41  | 12/8/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | M.dm | 117 | 3.90 | 2 | 30 | 174 | 47 | D | 146 | 47 | -2 | -4 | 3 | -1 | -1 | -1 | 1 | 14 | 36 | 18 | 4 | -17 | 
12/10/10 21:41  | 12/8/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | S.d | -438 | 21.92 | 2 | -20 | -30 | 47 | D | 146 | 47 | -2 | -4 | 3 | -1 | -1 | -1 | 1 | 14 | 36 | 18 | 4 | -17 | 
11/30/10 13:39  | 11/29/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 2 | 5 |  | 4 | D | 146 | 55 | -6 | 12 | -5 | -7 | 1 | 1 | -1 | 0 | 20 | 16 | 12 | -22 | 
11/30/10 13:39  | 11/29/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -111 | 22.24 | 2 | -5 | -55 | 4 | D | 146 | 55 | -6 | 12 | -5 | -7 | 1 | 1 | -1 | 0 | 20 | 16 | 12 | -22 | 
11/22/10 19:57  | 11/22/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Davis Stephen | CA | O | EVP,COO | S | -8 | 21.92 | 2 | 0 | -1 | 25 | D | 175 | 72 | -3 | 16 | -7 | 2 | -3 | -2 | 0 | 1 | 18 | 23 | 6 | -17 | 
11/1/10 13:04  | 10/28/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 1 | 5 |  | 4 | D | 167 | 52 | -16 | 4 | -14 | -10 | -6 | -3 | 1 | 10 | 4 | 24 | 29 | -2 | 
11/1/10 13:04  | 10/28/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -105 | 21.03 | 1 | -5 | -57 | 4 | D | 167 | 52 | -16 | 4 | -14 | -10 | -6 | -3 | 1 | 10 | 4 | 24 | 29 | -2 | 
9/30/10 14:32  | 9/28/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 2 | 5 |  | 4 | D | 75 | 25 | 26 | 12 | 15 | 4 | -7 | -1 | 0 | 2 | -8 | 17 | 27 | -32 | 
9/30/10 14:32  | 9/28/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -115 | 23.03 | 2 | -5 | -57 | 4 | D | 75 | 25 | 26 | 12 | 15 | 4 | -7 | -1 | 0 | 2 | -8 | 17 | 27 | -32 | 
9/24/10 13:33  | 9/23/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Poyhonen John | CA | D |  | M.d | 23 | 5.85 | 2 | 4 |  | 0 | D | 60 | 18 | 24 | 5 | 19 | 5 | -4 | -8 | 2 | 1 | -2 | 14 | 21 | -31 | 
9/24/10 13:33  | 9/23/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Poyhonen John | CA | D |  | S.d | -92 | 23.02 | 2 | -4 | -100 | 0 | D | 60 | 18 | 24 | 5 | 19 | 5 | -4 | -8 | 2 | 1 | -2 | 14 | 21 | -31 | 
9/1/10 11:49  | 8/30/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 20 | 3.90 | 2 | 5 |  | 4 | D | 51 | 14 | 37 | -15 | 13 | 5 | 4 | 4 | 5 | 9 | 14 | 10 | 30 | -21 | 
9/1/10 11:49  | 8/30/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -179 | 20.00 | 2 | -9 | -71 | 4 | D | 51 | 14 | 37 | -15 | 13 | 5 | 4 | 4 | 5 | 9 | 14 | 10 | 30 | -21 | 
8/10/10 19:39  | 8/9/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | M.d | 78 | 3.90 | 2 | 20 | 91 | 42 | D | 46 | 4 | 42 | -6 | -6 | 9 | 6 | -2 | -4 | -6 | 9 | 17 | 33 | -16 | 
8/10/10 19:39  | 8/9/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | S.d | -404 | 20.21 | 2 | -20 | -32 | 42 | D | 46 | 4 | 42 | -6 | -6 | 9 | 6 | -2 | -4 | -6 | 9 | 17 | 33 | -16 | 
7/29/10 12:18  | 7/28/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 10 | 3.90 | 2 | 3 | 48 | 8 | D | 45 | -4 | 31 | -25 | -21 | -4 | 3 | 1 | 2 | 10 | 1 | 15 | 50 | 22 | 
7/29/10 12:18  | 7/28/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -49 | 19.44 | 2 | -3 | -25 | 8 | D | 45 | -4 | 31 | -25 | -21 | -4 | 3 | 1 | 2 | 10 | 1 | 15 | 50 | 22 | 
7/26/10 11:35  | 7/23/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | M.d | 16 | 5.20 | 3 | 3 |  | 1 | D | 45 | -3 | 34 | -28 | -15 | -3 | -4 | 0 | 4 | 5 | 0 | 18 | 36 | 31 | 
7/26/10 11:35  | 7/23/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | S.d | -56 | 18.54 | 3 | -3 | -76 | 1 | D | 45 | -3 | 34 | -28 | -15 | -3 | -4 | 0 | 4 | 5 | 0 | 18 | 36 | 31 | 
7/14/10 12:09  | 7/12/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | M.d | 6 | 2.76 | 4 | 2 | 24 | 10 | D | 71 | 10 | 27 | -14 | -14 | -9 | 3 | 2 | -3 | -7 | -6 | 16 | 48 | 27 | 
7/14/10 12:09  | 7/12/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | S.d | -40 | 19.95 | 4 | -2 | -16 | 10 | D | 71 | 10 | 27 | -14 | -14 | -9 | 3 | 2 | -3 | -7 | -6 | 16 | 48 | 27 | 
6/29/10 16:39  | 6/28/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 10 | 3.90 | 4 | 3 | 48 | 8 | D | 58 | 41 | 49 | 18 | -7 | 3 | -11 | -2 | -2 | -9 | -8 | 11 | 26 | 19 | 
6/29/10 16:39  | 6/28/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -55 | 21.92 | 4 | -3 | -25 | 8 | D | 58 | 41 | 49 | 18 | -7 | 3 | -11 | -2 | -2 | -9 | -8 | 11 | 26 | 19 | 
6/24/10 18:10  | 6/23/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | M.d | 16 | 5.20 | 4 | 3 |  | 1 | D | 67 | 56 | 44 | 22 | -10 | -10 | -3 | -10 | 2 | -5 | -13 | 7 | 19 | 14 | 
6/24/10 18:10  | 6/23/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | S.d | -66 | 21.93 | 4 | -3 | -76 | 1 | D | 67 | 56 | 44 | 22 | -10 | -10 | -3 | -10 | 2 | -5 | -13 | 7 | 19 | 14 | 
6/14/10 12:09  | 6/10/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | M.d | 6 | 2.76 | 5 | 2 | 24 | 10 | D | 58 | 41 | 50 | 27 | -12 | -1 | -6 | 5 | 3 | 11 | -9 | 2 | -2 | 4 | 
6/14/10 12:09  | 6/10/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | S.d | -42 | 20.98 | 5 | -2 | -16 | 10 | D | 58 | 41 | 50 | 27 | -12 | -1 | -6 | 5 | 3 | 11 | -9 | 2 | -2 | 4 | 
6/1/10 17:26  | 5/28/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 10 | 3.90 | 6 | 3 | 48 | 8 | D | 75 | 60 | 69 | 73 | 0 | 13 | 9 | 12 | 0 | -8 | -11 | -15 | -5 | 4 | 
6/1/10 17:26  | 5/28/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -62 | 24.97 | 6 | -3 | -25 | 8 | D | 75 | 60 | 69 | 73 | 0 | 13 | 9 | 12 | 0 | -8 | -11 | -15 | -5 | 4 | 
5/26/10 19:07  | 5/24/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | M.d | 16 | 5.20 | 6 | 3 |  | 1 | D | 57 | 47 | 64 | 57 | -7 | -4 | -2 | -1 | 8 | 0 | -9 | -22 | -7 | -6 | 
5/26/10 19:07  | 5/24/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | S.d | -69 | 22.97 | 6 | -3 | -76 | 1 | D | 57 | 47 | 64 | 57 | -7 | -4 | -2 | -1 | 8 | 0 | -9 | -22 | -7 | -6 | 
5/18/10 12:19  | 5/17/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | S | -27 | 23.19 | 6 | -1 | -55 | 1 | D | 65 | 64 | 76 | 61 | 10 | -5 | 5 | -5 | 2 | -4 | 3 | -20 | -7 | 5 | 
5/17/10 14:47  | 5/14/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Beck John W | CA | O | SVP,Fina | M.d | 172 | 22.98 | 6 | 8 |  | 3 | D | 62 | 60 | 73 | 56 | 5 | -12 | -2 | -4 | 3 | -2 | 5 | -18 | -4 | 14 | 
5/11/10 15:18  | 5/10/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | M.d | 6 | 2.76 | 6 | 2 | 24 | 10 | D | 55 | 58 | 57 | 52 | 19 | -16 | -16 | -5 | 8 | 7 | -7 | -6 | 6 | 23 | 
5/11/10 15:18  | 5/10/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | S.d | -44 | 21.77 | 6 | -2 | -16 | 10 | D | 55 | 58 | 57 | 52 | 19 | -16 | -16 | -5 | 8 | 7 | -7 | -6 | 6 | 23 | 
5/7/10 21:50  | 5/7/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | M.d | 98 | 3.90 | 6 | 25 | 151 | 42 | D | 69 | 82 | 65 | 55 | 22 | -9 | -10 | -12 | 6 | 13 | 4 | 0 | 8 | 29 | 
5/7/10 21:50  | 5/7/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | S.d | -530 | 21.20 | 6 | -25 | -38 | 42 | D | 69 | 82 | 65 | 55 | 22 | -9 | -10 | -12 | 6 | 13 | 4 | 0 | 8 | 29 | 
4/29/10 12:04  | 4/28/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 10 | 3.90 | 7 | 3 | 52 | 7 | D | 85 | 93 | 73 | 74 | 36 | 18 | 1 | -4 | 3 | -8 | 1 | -25 | -13 | 11 | 
4/29/10 12:04  | 4/28/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -63 | 25.16 | 7 | -3 | -25 | 7 | D | 85 | 93 | 73 | 74 | 36 | 18 | 1 | -4 | 3 | -8 | 1 | -25 | -13 | 11 | 
4/26/10 13:20  | 4/23/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | M.d | 16 | 5.20 | 7 | 3 |  | 1 | D | 95 | 156 | 79 | 87 | 50 | 22 | 9 | 1 | -2 | -4 | -14 | -28 | -16 | 5 | 
4/26/10 13:20  | 4/23/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | S.d | -79 | 26.24 | 7 | -3 | -76 | 1 | D | 95 | 156 | 79 | 87 | 50 | 22 | 9 | 1 | -2 | -4 | -14 | -28 | -16 | 5 | 
4/13/10 13:23  | 4/12/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | M.d | 6 | 2.76 | 5 | 2 | 24 | 10 | D | 77 | 140 | 31 | 50 | 64 | 29 | 30 | 11 | 0 | 6 | 0 | -16 | 1 | 18 | 
4/13/10 13:23  | 4/12/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | S.d | -46 | 23.24 | 5 | -2 | -16 | 10 | D | 77 | 140 | 31 | 50 | 64 | 29 | 30 | 11 | 0 | 6 | 0 | -16 | 1 | 18 | 
4/8/10 16:17  | 4/6/10  | RDEA | Health | Drug | Pharmaceutical Preparations | 14159 Capital (Gp), LLC | NY | DT |  | P | 269 | 20.00 | 5 | 13 | 19 | 83 | I | 59 | 140 | 26 | 55 | 50 | 15 | 14 | 5 | 3 | 13 | 5 | -10 | 11 | 35 | 
4/8/10 16:13  | 4/6/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker Brothers Life Sciences Capital (Gp), LLC | NY | DT |  | P | 9,731 | 20.00 | 5 | 487 | 15 | 3,681 | I | 59 | 140 | 26 | 55 | 50 | 15 | 14 | 5 | 3 | 13 | 5 | -10 | 11 | 35 | 
3/30/10 15:53  | 3/29/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 10 | 3.90 | 2 | 3 | 52 | 7 | D | 43 | 65 | -2 | 26 | 26 | 15 | 0 | 1 | -3 | 16 | 37 | 18 | 26 | 50 | 
3/30/10 15:53  | 3/29/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -47 | 18.72 | 2 | -3 | -25 | 7 | D | 43 | 65 | -2 | 26 | 26 | 15 | 0 | 1 | -3 | 16 | 37 | 18 | 26 | 50 | 
3/24/10 14:28  | 3/23/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | M.d | 47 | 5.20 | 1 | 9 |  | 1 | D | 46 | 54 | 5 | 19 | 30 | 29 | 8 | 2 | -3 | -6 | 38 | 18 | 26 | 48 | 
3/24/10 14:28  | 3/23/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | S.d | -166 | 18.45 | 1 | -9 | -91 | 1 | D | 46 | 54 | 5 | 19 | 30 | 29 | 8 | 2 | -3 | -6 | 38 | 18 | 26 | 48 | 
3/12/10 12:02  | 3/10/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | M.d | 11 | 2.76 | 1 | 4 | 62 | 10 | D | 24 | 52 | -13 | 15 | 15 | 18 | 15 | 7 | 5 | 10 | 41 | 26 | 32 | 55 | 
3/12/10 12:02  | 3/10/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | S.d | -64 | 16.12 | 1 | -4 | -28 | 10 | D | 24 | 52 | -13 | 15 | 15 | 18 | 15 | 7 | 5 | 10 | 41 | 26 | 32 | 55 | 
3/1/10 15:18  | 2/26/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 10 | 3.90 | 1 | 3 | 52 | 7 | D | -2 | 17 | -22 | -2 | -11 | -3 | -2 | 2 | 1 | 8 | 30 | 80 | 35 | 90 | 
3/1/10 15:18  | 2/26/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -36 | 14.28 | 1 | -3 | -25 | 7 | D | -2 | 17 | -22 | -2 | -11 | -3 | -2 | 2 | 1 | 8 | 30 | 80 | 35 | 90 | 
2/10/10 16:30  | 2/8/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | M.d | 176 | 3.90 | 1 | 45 |  | 42 | D | 3 | 13 | -27 | 7 | 1 | -4 | -1 | 0 | 0 | 0 | 15 | 63 | 37 | 84 | 
2/10/10 16:30  | 2/8/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | S.d | -364 | 14.57 | 1 | -25 | -38 | 42 | D | 3 | 13 | -27 | 7 | 1 | -4 | -1 | 0 | 0 | 0 | 15 | 63 | 37 | 84 | 
1/29/10 12:09  | 1/28/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 10 | 3.90 | 1 | 3 | 52 | 7 | D | 4 | 23 | -25 | 1 | 1 | -5 | -6 | 4 | 0 | 0 | -1 | 80 | 34 | 92 | 
1/29/10 12:09  | 1/28/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -36 | 14.54 | 1 | -3 | -25 | 7 | D | 4 | 23 | -25 | 1 | 1 | -5 | -6 | 4 | 0 | 0 | -1 | 80 | 34 | 92 | 
1/12/10 14:33  | 1/11/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | M.d | 17 | 2.76 | 2 | 6 | 136 | 10 | D | 9 | 19 | -14 | -9 | 11 | 1 | 12 | 15 | 0 | -3 | -8 | 48 | 27 | 89 | 
1/12/10 14:33  | 1/11/10  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | S.d | -95 | 15.83 | 2 | -6 | -37 | 10 | D | 9 | 19 | -14 | -9 | 11 | 1 | 12 | 15 | 0 | -3 | -8 | 48 | 27 | 89 | 
12/29/09 19:52  | 12/28/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 10 | 3.90 | 2 | 3 | 52 | 7 | D | -3 | 25 | -9 | -27 | 12 | -2 | -3 | -6 | 1 | -3 | 2 | 25 | 46 | 86 | 
12/29/09 19:52  | 12/28/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -36 | 14.49 | 2 | -3 | -25 | 7 | D | -3 | 25 | -9 | -27 | 12 | -2 | -3 | -6 | 1 | -3 | 2 | 25 | 46 | 86 | 
12/24/09 13:16  | 12/23/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | M.d | 31 | 5.20 | 2 | 6 |  | 1 | D | -1 | 33 | 6 | -24 | 13 | 2 | 3 | -6 | -2 | -6 | -6 | 26 | 48 | 74 | 
12/24/09 13:16  | 12/23/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | S.d | -91 | 15.11 | 2 | -6 | -87 | 1 | D | -1 | 33 | 6 | -24 | 13 | 2 | 3 | -6 | -2 | -6 | -6 | 26 | 48 | 74 | 
12/11/09 17:09  | 12/9/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | M.d | 98 | 3.90 | 2 | 25 |  | 22 | D | 9 | 56 | -5 | -21 | 3 | 14 | 2 | -1 | 0 | 3 | 10 | 26 | 59 | 54 | 
12/11/09 17:09  | 12/9/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | S.d | -362 | 14.48 | 2 | -25 | -54 | 22 | D | 9 | 56 | -5 | -21 | 3 | 14 | 2 | -1 | 0 | 3 | 10 | 26 | 59 | 54 | 
12/1/09 12:09  | 11/27/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 10 | 3.90 | 1 | 3 | 52 | 7 | D | 4 | 47 | -17 | -24 | -23 | -3 | 7 | -7 | 5 | 9 | 6 | 9 | 77 | 65 | 
12/1/09 12:09  | 11/27/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -36 | 14.44 | 1 | -3 | -25 | 7 | D | 4 | 47 | -17 | -24 | -23 | -3 | 7 | -7 | 5 | 9 | 6 | 9 | 77 | 65 | 
11/10/09 19:48  | 11/9/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | M.d | 39 | 3.90 | 1 | 10 | 38 | 37 | D | 62 | 64 | -4 | -29 | -25 | -11 | -2 | 5 | -3 | -2 | 9 | 7 | 80 | 67 | 
10/29/09 12:10  | 10/28/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 10 | 3.90 | 2 | 3 | 64 | 6 | D | 61 | 76 | 14 | -29 | -23 | -23 | -20 | -5 | 0 | -6 | 3 | 4 | 81 | 51 | 
10/29/09 12:10  | 10/28/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -36 | 14.20 | 2 | -3 | -28 | 6 | D | 61 | 76 | 14 | -29 | -23 | -23 | -20 | -5 | 0 | -6 | 3 | 4 | 81 | 51 | 
10/26/09 12:14  | 10/23/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | M.d | 16 | 5.20 | 2 | 3 |  | 0 | D | 80 | 59 | 27 | -26 | -20 | -13 | -12 | -5 | -1 | -9 | -5 | -5 | 69 | 50 | 
10/26/09 12:14  | 10/23/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | S.d | -46 | 15.25 | 2 | -3 | -100 | 0 | D | 80 | 59 | 27 | -26 | -20 | -13 | -12 | -5 | -1 | -9 | -5 | -5 | 69 | 50 | 
10/14/09 11:33  | 10/12/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | M.d | 6 | 2.76 | 1 | 2 | 24 | 10 | D | 96 | 39 | 77 | -18 | -11 | -14 | -1 | -8 | 1 | -7 | -21 | -4 | 44 | 42 | 
10/14/09 11:33  | 10/12/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | S.d | -34 | 17.08 | 1 | -2 | -16 | 10 | D | 96 | 39 | 77 | -18 | -11 | -14 | -1 | -8 | 1 | -7 | -21 | -4 | 44 | 42 | 
9/29/09 19:44  | 9/28/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 10 | 3.90 | 2 | 3 | 64 | 6 | D | 132 | 41 | 72 | 24 | 0 | 2 | 8 | 1 | -1 | -7 | -20 | -20 | -3 | 23 | 
9/29/09 19:44  | 9/28/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -48 | 19.10 | 2 | -3 | -28 | 6 | D | 132 | 41 | 72 | 24 | 0 | 2 | 8 | 1 | -1 | -7 | -20 | -20 | -3 | 23 | 
9/24/09 12:05  | 9/23/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | M.d | 16 | 5.20 | 2 | 3 |  | 0 | D | 128 | 36 | 74 | 39 | -6 | 3 | 5 | 8 | 1 | -6 | -21 | -20 | -5 | 18 | 
9/24/09 12:05  | 9/23/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | S.d | -57 | 18.89 | 2 | -3 | -100 | 0 | D | 128 | 36 | 74 | 39 | -6 | 3 | 5 | 8 | 1 | -6 | -21 | -20 | -5 | 18 | 
9/14/09 12:02  | 9/10/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | M.d | 6 | 2.76 | 2 | 2 | 24 | 10 | D | 143 | 29 | 59 | 21 | -5 | -1 | -1 | -5 | 1 | -3 | -9 | -21 | -1 | 29 | 
9/14/09 12:02  | 9/10/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | S.d | -39 | 19.31 | 2 | -2 | -16 | 10 | D | 143 | 29 | 59 | 21 | -5 | -1 | -1 | -5 | 1 | -3 | -9 | -21 | -1 | 29 | 
8/31/09 20:51  | 8/28/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 10 | 3.90 | 2 | 3 | 64 | 6 | D | 151 | 22 | 65 | 12 | -4 | -10 | -9 | -4 | 5 | 7 | 4 | -18 | -18 | 12 | 
8/31/09 20:51  | 8/28/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -46 | 18.39 | 2 | -3 | -28 | 6 | D | 151 | 22 | 65 | 12 | -4 | -10 | -9 | -4 | 5 | 7 | 4 | -18 | -18 | 12 | 
8/25/09 12:28  | 8/24/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | M.d | 16 | 5.20 | 2 | 3 |  | 0 | D | 162 | 26 | 34 | 23 | -4 | -7 | -10 | -5 | 0 | -5 | 4 | -27 | -24 | 0 | 
8/25/09 12:28  | 8/24/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | S.d | -96 | 19.00 | 2 | -5 | -100 | 0 | D | 162 | 26 | 34 | 23 | -4 | -7 | -10 | -5 | 0 | -5 | 4 | -27 | -24 | 0 | 
8/17/09 19:26  | 8/14/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Beck John W | CA | O | SVP,Fina | M.d | 15 | 5.85 | 1 | 3 |  | 1 | D | 203 | 38 | 41 | 41 | 9 | 1 | 4 | 5 | 0 | -6 | -8 | -31 | -25 | -5 | 
8/17/09 19:26  | 8/14/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Beck John W | CA | O | SVP,Fina | S.d | -50 | 20.15 | 1 | -3 | -74 | 1 | D | 203 | 38 | 41 | 41 | 9 | 1 | 4 | 5 | 0 | -6 | -8 | -31 | -25 | -5 | 
8/13/09 20:20  | 8/11/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | M.dm | 137 | 3.90 | 2 | 35 |  | 27 | D | 203 | 40 | 60 | 43 | 26 | 5 | 2 | 4 | -3 | -5 | -12 | -35 | -30 | -8 | 
8/13/09 20:20  | 8/11/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | S.d | -483 | 19.33 | 2 | -25 | -49 | 27 | D | 203 | 40 | 60 | 43 | 26 | 5 | 2 | 4 | -3 | -5 | -12 | -35 | -30 | -8 | 
8/12/09 12:13  | 8/10/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | M.d | 6 | 2.76 | 2 | 2 | 24 | 10 | D | 185 | 32 | 55 | 34 | 23 | 1 | 0 | 2 | 6 | 2 | -1 | -29 | -24 | -1 | 
8/12/09 12:13  | 8/10/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Fuchs Henry J | CA | D |  | S.d | -40 | 19.85 | 2 | -2 | -16 | 10 | D | 185 | 32 | 55 | 34 | 23 | 1 | 0 | 2 | 6 | 2 | -1 | -29 | -24 | -1 | 
5/21/09 21:40  | 5/19/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | M.d | 98 | 3.90 | 1 | 25 |  | 6 | D | 204 | 8 | 59 | 6 | 63 | 22 | 4 | 5 | 0 | -2 | -2 | 30 | -16 | 48 | 
5/21/09 21:40  | 5/19/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Manhard Kimberly | CA | O | SVP,Regu | S.d | -321 | 15.05 | 1 | -21 | -77 | 6 | D | 204 | 8 | 59 | 6 | 63 | 22 | 4 | 5 | 0 | -2 | -2 | 30 | -16 | 48 | 
5/21/09 21:05  | 5/20/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Remington Jack | CA | D |  | M.d | 125 | 4.53 | 1 | 28 |  | 1 | D | 204 | 8 | 59 | 6 | 63 | 22 | 4 | 5 | 0 | -2 | -2 | 30 | -16 | 48 | 
5/21/09 21:05  | 5/20/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Remington Jack | CA | D |  | S.d | -411 | 14.95 | 1 | -28 | -96 | 1 | D | 204 | 8 | 59 | 6 | 63 | 22 | 4 | 5 | 0 | -2 | -2 | 30 | -16 | 48 | 
5/21/09 21:03  | 5/19/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Poyhonen John | CA | D |  | M.dm | 47 | 5.85 | 1 | 8 |  | 0 | D | 204 | 8 | 59 | 6 | 63 | 22 | 4 | 5 | 0 | -2 | -2 | 30 | -16 | 48 | 
5/21/09 21:03  | 5/19/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Poyhonen John | CA | D |  | S.dm | -122 | 15.21 | 1 | -8 | -100 | 0 | D | 204 | 8 | 59 | 6 | 63 | 22 | 4 | 5 | 0 | -2 | -2 | 30 | -16 | 48 | 
5/21/09 21:02  | 5/19/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | M.d | 117 | 3.90 | 1 | 30 |  | 27 | D | 204 | 8 | 59 | 6 | 63 | 22 | 4 | 5 | 0 | -2 | -2 | 30 | -16 | 48 | 
5/21/09 21:02  | 5/19/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | S.d | -385 | 15.39 | 1 | -25 | -49 | 27 | D | 204 | 8 | 59 | 6 | 63 | 22 | 4 | 5 | 0 | -2 | -2 | 30 | -16 | 48 | 
5/21/09 20:58  | 5/19/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | M.dm | 130 | 5.20 | 1 | 25 |  | 2 | D | 204 | 8 | 59 | 6 | 63 | 22 | 4 | 5 | 0 | -2 | -2 | 30 | -16 | 48 | 
5/21/09 20:58  | 5/19/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Krueger Christopher W | CA | O | SVP,CBO | S.dm | -413 | 15.02 | 1 | -28 | -93 | 2 | D | 204 | 8 | 59 | 6 | 63 | 22 | 4 | 5 | 0 | -2 | -2 | 30 | -16 | 48 | 
5/21/09 20:56  | 5/20/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Beck John W | CA | O | SVP,Fina | M.d | 29 | 5.85 | 1 | 5 |  | 1 | D | 204 | 8 | 59 | 6 | 63 | 22 | 4 | 5 | 0 | -2 | -2 | 30 | -16 | 48 | 
5/21/09 20:56  | 5/20/09  | RDEA | Health | Drug | Pharmaceutical Preparations | Beck John W | CA | O | SVP,Fina | S.d | -75 | 14.97 | 1 | -5 | -85 | 1 | D | 204 | 8 | 59 | 6 | 63 | 22 | 4 | 5 | 0 | -2 | -2 | 30 | -16 | 48 | 
12/19/08 21:12  | 12/17/08  | RDEA | Health | Drug | Pharmaceutical Preparations | Tang Kevin C | CA | DT |  | P.d | 1,745 | 11.14 | 0 | 157 | 5 | 3,531 | I | 190 | -13 | -16 | -22 | 40 | 24 | 27 | 33 | 7 | 8 | 11 | 14 | 34 | 45 | 
12/19/08 18:14  | 12/19/08  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker Bros. Capital (Gp), LLC | NY | T |  | P.d | 9 | 11.14 | 0 | 1 | 1 | 164 | I | 190 | -13 | -16 | -22 | 40 | 24 | 27 | 33 | 7 | 8 | 11 | 14 | 34 | 45 | 
12/19/08 18:13  | 12/19/08  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker Brothers Life Sciences Capital (Gp), LLC | NY | T |  | P.d | 6,563 | 11.14 | 0 | 589 | 23 | 3,194 | I | 190 | -13 | -16 | -22 | 40 | 24 | 27 | 33 | 7 | 8 | 11 | 14 | 34 | 45 | 
12/19/08 18:11  | 12/19/08  | RDEA | Health | Drug | Pharmaceutical Preparations | 14159 Capital (Gp), LLC | NY | T |  | P.d | 179 | 11.14 | 0 | 16 | 30 | 70 | I | 190 | -13 | -16 | -22 | 40 | 24 | 27 | 33 | 7 | 8 | 11 | 14 | 34 | 45 | 
12/19/08 16:52  | 12/19/08  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker Biotech Capital (Gp), LLC | NY | T |  | P.d | 2,058 | 11.14 | 0 | 185 | 13 | 1,647 | I | 190 | -13 | -16 | -22 | 40 | 24 | 27 | 33 | 7 | 8 | 11 | 14 | 34 | 45 | 
12/19/08 16:49  | 12/19/08  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker Biotech Capital (Gp), LLC | NY | T |  | P.d | 2,058 | 11.14 | 0 | 185 | 13 | 1,647 | I | 190 | -13 | -16 | -22 | 40 | 24 | 27 | 33 | 7 | 8 | 11 | 14 | 34 | 45 | 
12/19/08 16:16  | 12/19/08  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker / Tisch Capital (Gp), LLC | NY | T |  | P.ad | 44 | 11.14 | 0 | 4 | 4 | 100 | I | 190 | -13 | -16 | -22 | 40 | 24 | 27 | 33 | 7 | 8 | 11 | 14 | 34 | 45 | 
12/19/08 12:59  | 12/19/08  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker / Tisch Capital (Gp), LLC | NY | T |  | P.d | 44 | 11.14 | 0 | 4 | 4 | 96 | I | 190 | -13 | -16 | -22 | 40 | 24 | 27 | 33 | -5 | 3 | 6 | 9 | 29 | 40 | 
9/22/08 14:31  | 9/22/08  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | M.d | 20 | 3.90 | 1 | 5 | 32 | 21 | D | 284 | 60 | 11 | 7 | -2 | 8 | -2 | 1 | -3 | -3 | -17 | -22 | -15 | 25 | 
9/4/08 19:26  | 9/3/08  | RDEA | Health | Drug | Pharmaceutical Preparations | Quart Barry D | CA | DO | P,CEO | M.d | 59 | 3.90 | 0 | 15 | 999% | 16 | D | 285 | 89 | -4 | -6 | 3 | -8 | -9 | -9 | -1 | 5 | -10 | -44 | -24 | 37 | 
4/21/08 18:14  | 4/17/08  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker Bros. Capital (Gp), LLC | NY | T |  | P | 1 | 13.28 | 2 | 0 | 0 | 137 | I | 307 | 183 | 64 | 4 | 6 | 14 | 9 | 12 | -3 | -4 | 2 | -8 | -10 | -31 | 
4/21/08 18:13  | 4/17/08  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker Biotech Capital (Gp), LLC | NY | T |  | P | 147 | 13.28 | 2 | 11 | 1 | 1,168 | I | 307 | 183 | 64 | 4 | 6 | 14 | 9 | 12 | -3 | -4 | 2 | -8 | -10 | -31 | 
4/21/08 18:12  | 4/17/08  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker Brothers Life Sciences Capital (Gp), LLC | NY | T |  | P | 372 | 13.28 | 2 | 28 | 1 | 2,273 | I | 307 | 183 | 64 | 4 | 6 | 14 | 9 | 12 | -3 | -4 | 2 | -8 | -10 | -31 | 
4/21/08 18:10  | 4/17/08  | RDEA | Health | Drug | Pharmaceutical Preparations | 14159 Capital (Gp), LLC | NY | T |  | P | 12 | 13.28 | 2 | 1 | 2 | 54 | I | 307 | 183 | 64 | 4 | 6 | 14 | 9 | 12 | -3 | -4 | 2 | -8 | -10 | -31 | 
4/8/08 16:27  | 4/4/08  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker Brothers Life Sciences Capital (Gp), LLC | NY | T |  | P | 4,159 | 13.28 | 1 | 313 | 16 | 2,245 | I | 280 | 170 | 53 | -16 | -5 | 4 | 3 | 4 | 3 | 4 | 1 | -20 | -8 | -32 | 
4/8/08 16:25  | 4/4/08  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker Biotech Capital (Gp), LLC | NY | T |  | P | 1,011 | 13.28 | 1 | 76 | 7 | 1,157 | I | 280 | 170 | 53 | -16 | -5 | 4 | 3 | 4 | 3 | 4 | 1 | -20 | -8 | -32 | 
4/8/08 16:24  | 4/4/08  | RDEA | Health | Drug | Pharmaceutical Preparations | 14159 Capital (Gp), LLC | NY | T |  | P | 132 | 13.28 | 1 | 10 | 23 | 53 | I | 280 | 170 | 53 | -16 | -5 | 4 | 3 | 4 | 3 | 4 | 1 | -20 | -8 | -32 | 
4/8/08 16:22  | 4/8/08  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker Bros. Capital (Gp), LLC | NY | T |  | P | 10 | 13.28 | 1 | 1 | 1 | 137 | I | 280 | 170 | 53 | -16 | -5 | 4 | 3 | 4 | 3 | 4 | 1 | -20 | -8 | -32 | 
1/11/08 16:42  | 1/9/08  | RDEA | Health | Drug | Pharmaceutical Preparations | Andreeff Dane | LA | T |  | P | 4 | 15.94 | 0 | 0 |  | 0 | I | 303 | 189 | 168 | 70 | 25 | 13 | -4 | -1 | -2 | -6 | -5 | -8 | -22 | -11 | 
1/3/08 20:11  | 12/26/07  | RDEA | Health | Drug | Pharmaceutical Preparations | Andreeff Dane | LA | T |  | P.m | 187 | 15.18 | 0 | 12 | 1 | 1,221 | I | 336 | 260 | 166 | 76 | 78 | 18 | 12 | 5 | -1 | -7 | -14 | -21 | -30 | -27 | 
12/21/07 16:57  | 12/19/07  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker / Tisch Capital (Gp), LLC | NY | T |  | P | 209 | 13.25 | 0 | 16 | 42 | 53 | I | 284 | 259 | 137 | 63 | 65 | 6 | 5 | 8 | 4 | 2 | -8 | -11 | -9 | -28 | 
12/21/07 16:55  | 12/19/07  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker Bros. Capital (Gp), LLC | NY | T |  | P | 27 | 13.25 | 0 | 2 | 2 | 136 | I | 284 | 259 | 137 | 63 | 65 | 6 | 5 | 8 | 4 | 2 | -8 | -11 | -9 | -28 | 
12/21/07 16:48  | 12/19/07  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker Biotech Capital (Gp), LLC | NY | T |  | P | 3,949 | 13.25 | 0 | 298 | 38 | 1,079 | I | 284 | 259 | 137 | 63 | 65 | 6 | 5 | 8 | 4 | 2 | -8 | -11 | -9 | -28 | 
12/21/07 16:47  | 12/19/07  | RDEA | Health | Drug | Pharmaceutical Preparations | Baker Brothers Life Sciences Capital (Gp), LLC | NY | T |  | P.d | 9,997 | 13.25 | 0 | 755 | 64 | 1,930 | I | 284 | 259 | 137 | 63 | 65 | 6 | 5 | 8 | 4 | 2 | -8 | -11 | -9 | -28 | 
12/21/07 16:46  | 12/19/07  | RDEA | Health | Drug | Pharmaceutical Preparations | 14159 Capital (Gp), LLC | NY | T |  | P | 318 | 13.25 | 0 | 24 | 125 | 43 | I | 284 | 259 | 137 | 63 | 65 | 6 | 5 | 8 | 4 | 2 | -8 | -11 | -9 | -28 | 
12/21/07 16:10  | 12/19/07  | RDEA | Health | Drug | Pharmaceutical Preparations | Tang Kevin C | CA | DT |  | P | 500 | 13.25 | 0 | 38 | 2 | 2,512 | I | 284 | 259 | 137 | 63 | 65 | 6 | 5 | 8 | 4 | 2 | -8 | -11 | -9 | -28 | 
12/17/07 21:31  | 12/13/07  | ARDC | Health | Drug | Pharmaceutical Preparations | Hickey Denis | CA | O | CFO | S | -54 | 12.88 | 0 | -4 | -100 | 0 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/6/07 17:02  | 12/5/07  | ARDC | Health | Drug | Pharmaceutical Preparations | Remington Jack | CA | D |  | M.d | 53 | 3.34 | 0 | 16 |  | 0 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  |