| 2/2/22 21:25 | 2/2/22 | SRRA | Health | Drug | Pharmaceutical Preparations | Longitude Capital Partners Iii, LLC | CA | T |  | P | 4,725 | 27.00 | 0 | 175 | 9 | 2,140 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 2/2/22 21:24 | 2/2/22 | SRRA | Health | Drug | Pharmaceutical Preparations | Richardson Joshua | A1 | DT |  | P | 4,725 | 27.00 | 0 | 175 | 9 | 2,140 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 2/1/22 17:04 | 1/31/22 | SRRA | Health | Drug | Pharmaceutical Preparations | Sinclair Andrew | A1 | D |  | P.d | 4,050 | 27.00 | 0 | 150 | 13 | 1,314 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 2/1/22 17:00 | 1/31/22 | SRRA | Health | Drug | Pharmaceutical Preparations | Abingworth LLP | X0 | T |  | P.d | 4,050 | 27.00 | 0 | 150 | 13 | 1,314 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 1/31/22 21:30 | 1/31/22 | SRRA | Health | Drug | Pharmaceutical Preparations | Vivo Opportunity, LLC | CA | T |  | P | 21,600 | 27.00 | 0 | 800 | 32 | 3,330 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 1/31/22 18:47 | 1/31/22 | SRRA | Health | Drug | Pharmaceutical Preparations | Aggarwal Gaurav | CA | DT |  | P | 21,600 | 27.00 | 0 | 800 | 41 | 2,736 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 11/24/21 19:07 | 11/23/21 | SRRA | Health | Drug | Pharmaceutical Preparations | Collard Craig A | CA | D |  | P.m | 311 | 23.03 | 0 | 14 | New | 14 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 5/20/21 18:59 | 5/19/21 | SRRA | Health | Drug | Pharmaceutical Preparations | Dilly Stephen George | CA | DO | CEO,P | P | 89 | 17.83 | 0 | 5 | New | 5 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 8/18/20 20:16 | 8/18/20 | SRRA | Health | Drug | Pharmaceutical Preparations | Klencke Barbara | A1 | O | Chief De | P | 113 | 12.23 | 0 | 9 | 162 | 15 | M |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 8/26/19 17:07 | 8/22/19 | SRRA | Health | Drug | Pharmaceutical Preparations | Klencke Barbara | A1 | O | Chief De | P.m | 101 | 0.4395 | 0 | 229 | New | 229 | M |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 12/11/18 17:38 | 12/10/18 | SRRA | Health | Drug | Pharmaceutical Preparations | Allen Andrew R | A1 | D |  | P | 108 | 1.64 | 0 | 66 | New | 66 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 3/9/17 18:01 | 3/8/17 | SRRA | Health | Drug | Pharmaceutical Preparations | You Angie | A1 | O | Chief Bu | P | 43 | 1.43 | 1 | 30 | 29 | 133 | D |  | -78 | -24 | -4 | -1 | 0 | -6 | -5 | 4 | 4 | 0 |  |  |  | 
| 2/16/17 17:11 | 2/14/17 | SRRA | Health | Drug | Pharmaceutical Preparations | Topper James N | WA | DT |  | P | 8,000 | 1.35 | 0 | 5,926 | 271 | 8,112 | I |  | -80 | -26 | -7 | -11 | 2 | -3 | 4 | 2 | 2 | 6 |  |  |  | 
| 7/21/15 19:06 | 7/21/15 | DNAI | Health | Drug | Pharmaceutical Preparations | Vivo Ventures Vii, LLC | CA | H | Former 1 | P.d | 3,740 | 17.00 | 33 | 220 | 5 | 4,872 | I |  |  |  |  |  |  |  |  | 1 | -13 | -3 | -40 | -66 | -92 | 
| 7/21/15 19:04 | 7/21/15 | DNAI | Health | Drug | Pharmaceutical Preparations | Topper James N | WA | D |  | P.d | 3,740 | 17.00 | 33 | 220 | 11 | 2,186 | I |  |  |  |  |  |  |  |  | 1 | -13 | -3 | -40 | -66 | -92 | 
| 7/21/15 19:03 | 7/21/15 | DNAI | Health | Drug | Pharmaceutical Preparations | Thompson Peter A. | A1 | D |  | P.d | 2,975 | 17.00 | 33 | 175 | 10 | 1,990 | I |  |  |  |  |  |  |  |  | 1 | -13 | -3 | -40 | -66 | -92 | 
| 7/21/15 19:00 | 7/21/15 | DNAI | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | P.d | 2,975 | 17.00 | 33 | 175 | 10 | 1,990 | I |  |  |  |  |  |  |  |  | 1 | -13 | -3 | -40 | -66 | -92 | 
| 7/21/15 18:59 | 7/21/15 | DNAI | Health | Drug | Pharmaceutical Preparations | Cha Albert | CA | D |  | P.d | 3,740 | 17.00 | 33 | 220 | 5 | 4,872 | I |  |  |  |  |  |  |  |  | 1 | -13 | -3 | -40 | -66 | -92 |