4/4/22 16:17  | 4/1/22  | ARAV | Health | Drug | Pharmaceutical Preparations | Eshelman Fredric N | TX | DOT | Exec CB | M.d | 0 | 0.0001 | 0 | 4,545 | 97 | 9,212 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/2/21 19:28  | 11/30/21  | ARAV | Health | Drug | Pharmaceutical Preparations | Giaccia Amato | TX | D |  | M.d | 10 | 0.1969 | 0 | 52 | 5 | 990 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/2/21 19:28  | 11/30/21  | ARAV | Health | Drug | Pharmaceutical Preparations | Giaccia Amato | TX | D |  | S.d | -10 | 3.22 | 0 | -3 | 0 | 990 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/29/21 19:37  | 6/29/21  | ARAV | Health | Drug | Pharmaceutical Preparations | McIntyre Gail Frances | TX | DO | CEO,P | P | 5 | 5.35 | 0 | 1 | 10 | 11 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/29/21 19:36  | 6/29/21  | ARAV | Health | Drug | Pharmaceutical Preparations | Shah Vinay | TX | O | CFO | P | 5 | 5.31 | 0 | 1 | 1 | 191 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/22/21 19:13  | 3/19/21  | ARAV | Health | Drug | Pharmaceutical Preparations | Giaccia Amato | TX | D |  | M.d | 1 | 0.0600 | 0 | 12 | 1 | 942 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/7/20 20:05  | 12/4/20  | ARAV | Health | Drug | Pharmaceutical Preparations | Shah Vinay | TX | O | CFO | P | 46 | 5.76 | 0 | 8 | 4 | 190 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/7/20 20:00  | 12/4/20  | ARAV | Health | Drug | Pharmaceutical Preparations | McIntyre Gail Frances | TX | DO | CEO,P | P | 46 | 5.77 | 0 | 8 | 374 | 10 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/2/19 16:05  | 12/2/19  | ARAV | Health | Drug | Pharmaceutical Preparations | Akkaraju Srinivas | TX | D |  | P | 1,000 | 7.50 | 0 | 133 | 28 | 608 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
10/8/19 16:08  | 10/7/19  | ARAV | Health | Drug | Pharmaceutical Preparations | Shepard Jay | TX | DO | P,CEO | S | -27 | 6.82 | 0 | -4 | -5 | 73 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
5/13/19 18:15  | 5/10/19  | ARAV | Health | Drug | Pharmaceutical Preparations | Shepard Jay | TX | DO | P,CEO | S | -7 | 6.11 | 0 | -1 | -2 | 77 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
2/5/19 19:53  | 2/1/19  | ARAV | Health | Drug | Pharmaceutical Preparations | Shepard Jay | TX | DO | P,CEO | S | -9 | 4.14 | 0 | -2 | -3 | 82 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
2/5/19 19:52  | 2/1/19  | ARAV | Health | Drug | Pharmaceutical Preparations | Haas Kevin | TX | O | VP,Finan | S | -1 | 4.14 | 0 | 0 | -2 | 11 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/26/18 20:01  | 12/21/18  | ARAV | Health | Drug | Pharmaceutical Preparations | Shepard Jay | TX | DO | P,CEO | S | -11 | 3.22 | 0 | -3 | -4 | 84 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/26/18 19:56  | 12/21/18  | ARAV | Health | Drug | Pharmaceutical Preparations | Haas Kevin | TX | O | VP,Finan | S | -2 | 3.22 | 0 | -1 | -6 | 11 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/19/18 19:59  | 12/17/18  | ARAV | Health | Drug | Pharmaceutical Preparations | Shepard Jay | TX | DO | P,CEO | S | -45 | 3.96 | 0 | -11 | -11 | 88 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/19/18 19:57  | 12/17/18  | ARAV | Health | Drug | Pharmaceutical Preparations | Haas Kevin | TX | O | VP,Finan | S | -5 | 3.96 | 0 | -1 | -9 | 12 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/19/18 16:54  | 6/15/18  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Chie | S | -1 | 2.30 | 0 | -1 | 0 | 225 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/19/18 16:52  | 6/15/18  | VSAR | Health | Drug | Pharmaceutical Preparations | Haas Kevin | CA | O | VP,Finan | S | 0 | 2.30 | 0 | 0 | 0 | 78 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/15/18 21:44  | 6/13/18  | VSAR | Health | Drug | Pharmaceutical Preparations | Akkaraju Srinivas | CA | D |  | P | 113 | 2.13 | 0 | 53 | 2 | 2,683 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/8/18 18:34  | 6/6/18  | VSAR | Health | Drug | Pharmaceutical Preparations | Akkaraju Srinivas | CA | D |  | P.m | 1,915 | 1.81 | 0 | 1,055 | 67 | 2,630 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
5/23/18 17:42  | 5/22/18  | VSAR | Health | Drug | Pharmaceutical Preparations | Shepard Jay | CA | DO | P,CEO | S | -14 | 1.50 | 0 | -9 | -2 | 593 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/25/18 18:10  | 4/24/18  | VSAR | Health | Drug | Pharmaceutical Preparations | Stout Jay S | CA | O | SVP,Tech | S | -8 | 1.55 | 0 | -5 | -3 | 186 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/26/18 18:54  | 3/23/18  | VSAR | Health | Drug | Pharmaceutical Preparations | Woody Tracy M | CA | O | Chief Co | S | -8 | 1.75 | 0 | -4 | -2 | 216 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
2/12/18 17:27  | 2/8/18  | VSAR | Health | Drug | Pharmaceutical Preparations | Haas Kevin | CA | O | VP,Finan | S | -3 | 1.80 | 0 | -2 | -2 | 78 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
2/12/18 17:25  | 2/8/18  | VSAR | Health | Drug | Pharmaceutical Preparations | Shepard Jay | CA | DO | P,CEO | S | -26 | 1.80 | 0 | -14 | -2 | 602 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
2/12/18 17:23  | 2/8/18  | VSAR | Health | Drug | Pharmaceutical Preparations | Ward Shane | CA | O | SVP,GC | S | -7 | 1.80 | 0 | -4 | -2 | 202 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
2/12/18 17:20  | 2/8/18  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Chie | S | -10 | 1.80 | 0 | -5 | -2 | 226 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/5/17 19:38  | 12/1/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Akkaraju Srinivas | CA | D |  | P.m | 2,115 | 2.17 | 0 | 976 | 167 | 1,563 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
10/23/17 17:02  | 10/19/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Chie | S | -3 | 2.55 | 0 | -1 | -1 | 125 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
10/23/17 17:01  | 10/19/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Ward Shane | CA | O | SVP,GC | S | -2 | 2.55 | 0 | -1 | -1 | 93 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
10/23/17 16:59  | 10/19/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Hislop Colin | CA | O | Chief Me | S | -2 | 2.55 | 0 | -1 | -3 | 24 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
10/23/17 16:58  | 10/19/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Brumm Joshua T | CA | O | COO,CFO | S | -3 | 2.55 | 0 | -1 | -1 | 201 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
9/25/17 16:07  | 9/21/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Perceptive Advisors LLC | NY | T |  | S.m | -7,014 | 3.29 | 0 | -2,130 | -50 | 2,100 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/14/17 18:51  | 6/13/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Chie | S | -11 | 16.05 | 0 | -1 | -1 | 68 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/14/17 18:50  | 6/13/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Brumm Joshua T | CA | O | COO,CFO | S | -23 | 16.05 | 0 | -1 | -1 | 106 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
5/17/17 18:29  | 5/16/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Brumm Joshua T | CA | O | COO,CFO | S | -22 | 17.40 | 4 | -1 | -1 | 107 | D | 17 | 141 | 53 | 16 | -18 | -11 | -4 | -1 |  |  |  |  |  |  | 
4/20/17 17:23  | 4/19/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Chie | S | -26 | 19.85 | 5 | -1 | -2 | 68 | D | 7 | 105 | 66 | 32 | 0 | -8 | -2 | -3 | 0 | 1 |  |  |  |  | 
4/5/17 19:02  | 4/4/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Hislop Colin | CA | O | Chief Me | M.d | 286 | 8.17 | 9 | 35 |  | 25 | D | 22 | 154 | 75 | 43 | 9 | 12 | 1 | -3 | -1 | -1 | -18 |  |  |  | 
4/5/17 19:02  | 4/4/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Hislop Colin | CA | O | Chief Me | S.d | -742 | 21.20 | 9 | -35 | -59 | 25 | D | 22 | 154 | 75 | 43 | 9 | 12 | 1 | -3 | -1 | -1 | -18 |  |  |  | 
3/28/17 20:06  | 3/24/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Akkaraju Srinivas | CA | D |  | P | 7,000 | 12.25 | 9 | 571 | 999% | 583 | I | 6 | 223 | 61 | 40 | 36 | 5 | 15 | 5 | 2 | -1 | -8 |  |  |  | 
3/17/17 17:29  | 3/16/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Malik Shahzad | X0 | D |  | S.m | -8,759 | 18.11 | 8 | -484 | -23 | 1,631 | I | -7 | 181 | 41 | 42 | 36 | -17 | -8 | -5 | 8 | 8 | 7 |  |  |  | 
3/15/17 17:44  | 3/13/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Malik Shahzad | X0 | D |  | S.m | -3,175 | 19.09 | 8 | -166 | -7 | 2,114 | I | -4 | 175 | 40 | 45 | 33 | -3 | -11 | -5 | -3 | 4 | 8 |  |  |  | 
3/15/17 17:31  | 3/14/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Ward Shane | CA | O | SVP,GC | S.m | -39 | 19.01 | 8 | -2 | -5 | 36 | D | -4 | 175 | 40 | 45 | 33 | -3 | -11 | -5 | -3 | 4 | 8 |  |  |  | 
3/14/17 16:30  | 2/10/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Perceptive Advisors LLC | NY | T |  | P.am | 1,439 | 15.30 | 7 | 94 | 2 | 4,230 | I | -3 | 179 | 42 | 46 | 49 | 2 | -8 | -4 | 0 | 8 | 8 |  |  |  | 
2/28/17 19:36  | 2/27/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Chie | M.d | 25 | 1.98 | 4 | 13 | 22 | 70 | D | 13 | 247 | 84 | 73 | 46 | 66 | 44 | 18 | 0 | -8 | -1 |  |  |  | 
2/28/17 19:36  | 2/27/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Chie | S.d | -281 | 22.50 | 4 | -13 | -15 | 70 | D | 13 | 247 | 84 | 73 | 46 | 66 | 44 | 18 | 0 | -8 | -1 |  |  |  | 
2/28/17 19:34  | 2/27/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Shepard Jay | CA | DO | P,CEO | M.d | 13 | 2.53 | 4 | 5 | 2 | 214 | D | 13 | 247 | 84 | 73 | 46 | 66 | 44 | 18 | 0 | -8 | -1 |  |  |  | 
2/28/17 19:34  | 2/27/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Shepard Jay | CA | DO | P,CEO | S.d | -124 | 24.00 | 4 | -5 | -2 | 214 | D | 13 | 247 | 84 | 73 | 46 | 66 | 44 | 18 | 0 | -8 | -1 |  |  |  | 
2/28/17 19:33  | 2/24/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Brumm Joshua T | CA | O | COO,CFO | M.d | 76 | 2.53 | 4 | 30 | 40 | 106 | D | 13 | 247 | 84 | 73 | 46 | 66 | 44 | 18 | 0 | -8 | -1 |  |  |  | 
2/28/17 19:33  | 2/24/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Brumm Joshua T | CA | O | COO,CFO | S.d | -628 | 20.94 | 4 | -30 | -22 | 106 | D | 13 | 247 | 84 | 73 | 46 | 66 | 44 | 18 | 0 | -8 | -1 |  |  |  | 
2/23/17 20:25  | 2/21/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Chie | M.dm | 40 | 1.61 | 3 | 25 | 56 | 70 | D | 0 | 204 | 49 | 49 | 24 | 40 | 30 | 24 | 6 | 4 | -3 |  |  |  | 
2/23/17 20:25  | 2/21/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Chie | S.dm | -469 | 18.75 | 3 | -25 | -26 | 70 | D | 0 | 204 | 49 | 49 | 24 | 40 | 30 | 24 | 6 | 4 | -3 |  |  |  | 
2/23/17 20:23  | 2/21/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Shepard Jay | CA | DO | P,CEO | M.dm | 40 | 2.53 | 3 | 16 | 8 | 214 | D | 0 | 204 | 49 | 49 | 24 | 40 | 30 | 24 | 6 | 4 | -3 |  |  |  | 
2/23/17 20:23  | 2/21/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Shepard Jay | CA | DO | P,CEO | S.dm | -308 | 19.25 | 3 | -16 | -7 | 214 | D | 0 | 204 | 49 | 49 | 24 | 40 | 30 | 24 | 6 | 4 | -3 |  |  |  | 
2/14/17 08:45  | 2/10/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Perceptive Advisors LLC | NY | T |  | P.m | 1,439 | 15.30 | 1 | 94 | 2 | 4,229 | I | -16 | 91 | 21 | 31 | 5 | 5 | 15 | 14 | -1 | 21 | 22 |  |  |  | 
2/10/17 08:45  | 2/8/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Perceptive Advisors LLC | NY | T |  | P.m | 2,001 | 13.72 | 1 | 146 | 4 | 4,135 | I | -18 | 67 | 27 | 42 | -5 | -4 | 1 | 4 | 4 | 9 | 34 | 20 |  |  | 
2/6/17 17:23  | 2/3/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Shepard Jay | CA | DO | P,CEO | S | -92 | 13.69 | 1 | -7 | -3 | 214 | D | -17 | 46 | 26 | 42 | -7 | -11 | -6 | -1 | -4 | 9 | 45 | 27 |  |  | 
2/2/17 20:12  | 1/31/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Shepard Jay | CA | DO | P,CEO | M.dm | 54 | 2.53 | 1 | 21 | 11 | 221 | D | -20 | 38 | 29 | 26 | -6 | -10 | -5 | -2 | 4 | 1 | 56 | 33 |  |  | 
2/2/17 20:12  | 1/31/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Shepard Jay | CA | DO | P,CEO | S.dm | -333 | 13.77 | 1 | -24 | -10 | 221 | D | -20 | 38 | 29 | 26 | -6 | -10 | -5 | -2 | 4 | 1 | 56 | 33 |  |  | 
1/31/17 20:36  | 1/30/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Brumm Joshua T | CA | O | COO,CFO | S.d | -41 | 13.85 | 1 | -3 | -3 | 106 | D | -30 | 17 | 13 | 10 | -2 | -18 | -14 | -14 | -2 | -4 | 58 | 33 |  |  | 
1/31/17 20:34  | 1/30/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Shepard Jay | CA | DO | P,CEO | S.d | -233 | 13.52 | 1 | -17 | -7 | 223 | D | -30 | 17 | 13 | 10 | -2 | -18 | -14 | -14 | -2 | -4 | 58 | 33 |  |  | 
1/31/17 20:34  | 1/30/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Shepard Jay | CA | DO | P,CEO | M.d | 27 | 2.53 | 1 | 11 | 5 | 223 | D | -30 | 17 | 13 | 10 | -2 | -18 | -14 | -14 | -2 | -4 | 58 | 33 |  |  | 
1/31/17 20:31  | 1/30/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Ward Shane | CA | O | SVP,GC | S.d | -20 | 13.85 | 1 | -1 | -4 | 38 | D | -30 | 17 | 13 | 10 | -2 | -18 | -14 | -14 | -2 | -4 | 58 | 33 |  |  | 
1/31/17 20:29  | 1/30/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Chie | S.d | -27 | 13.85 | 1 | -2 | -3 | 70 | D | -30 | 17 | 13 | 10 | -2 | -18 | -14 | -14 | -2 | -4 | 58 | 33 |  |  | 
1/11/17 21:21  | 1/9/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Corp | M.dm | 47 | 1.43 | 2 | 33 | 269 | 45 | D | -32 | 64 | 47 | 28 | 25 | 5 | 9 | -1 | -1 | -2 | -7 | 32 |  |  | 
1/11/17 21:21  | 1/9/17  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Corp | S.dm | -509 | 15.67 | 2 | -33 | -42 | 45 | D | -32 | 64 | 47 | 28 | 25 | 5 | 9 | -1 | -1 | -2 | -7 | 32 |  |  | 
1/4/17 14:51  | 12/30/16  | VSAR | Health | Drug | Pharmaceutical Preparations | Perceptive Advisors LLC | NY | T |  | P.a | 1,042 | 14.66 | 2 | 71 | 2 | 3,990 | I | -33 | 24 | 41 | 23 | 14 | 15 | -1 | -2 | 7 | 5 | -9 | 43 |  |  | 
1/4/17 14:26  | 12/30/16  | VSAR | Health | Drug | Pharmaceutical Preparations | Perceptive Advisors LLC | NY | T |  | P | 1,389 | 14.66 | 2 | 95 | 2 | 4,013 | I | -33 | 24 | 41 | 23 | 14 | 15 | -1 | -2 | 7 | 5 | -9 | 43 |  |  | 
12/30/16 08:46  | 12/29/16  | VSAR | Health | Drug | Pharmaceutical Preparations | Perceptive Advisors LLC | NY | T |  | P | 681 | 14.37 | 2 | 47 | 1 | 3,919 | I | -32 | 16 | 31 | 19 | 15 | 9 | -3 | -9 | 3 | 12 | -1 | 48 |  |  | 
12/29/16 18:19  | 12/27/16  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Corp | S | -6 | 15.85 | 2 | 0 | -1 | 45 | D | -31 | 20 | 39 | 24 | 18 | 17 | 2 | 0 | 3 | 9 | -10 | 50 |  |  | 
12/29/16 18:15  | 12/27/16  | VSAR | Health | Drug | Pharmaceutical Preparations | Brumm Joshua T | CA | O | CFO | S | -16 | 15.85 | 2 | -1 | -2 | 65 | D | -31 | 20 | 39 | 24 | 18 | 17 | 2 | 0 | 3 | 9 | -10 | 50 |  |  | 
12/19/16 19:37  | 12/16/16  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Corp | M.d | 6 | 1.27 | 2 | 5 | 13 | 45 | D | -23 | 40 | 36 | 19 | 63 | 18 | 15 | 15 | 6 | 7 | 1 | 32 |  |  | 
12/19/16 19:37  | 12/16/16  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Corp | S.d | -75 | 15.00 | 2 | -5 | -10 | 45 | D | -23 | 40 | 36 | 19 | 63 | 18 | 15 | 15 | 6 | 7 | 1 | 32 |  |  | 
12/8/16 21:10  | 12/8/16  | VSAR | Health | Drug | Pharmaceutical Preparations | Jennings Edmon R | CA | D |  | S | -19 | 12.96 | 2 | -2 | -16 | 8 | D | -30 | 11 | 20 | -8 | 7 | 2 | 2 | 2 | -2 | -4 | 20 | 50 |  |  | 
12/8/16 17:18  | 12/7/16  | VSAR | Health | Drug | Pharmaceutical Preparations | Brumm Joshua T | CA | O | CFO | S | -40 | 13.25 | 2 | -3 | -4 | 66 | D | -30 | 11 | 20 | -8 | 7 | 2 | 2 | 2 | -2 | -4 | 20 | 50 |  |  | 
10/4/16 12:41  | 10/3/16  | VSAR | Health | Drug | Pharmaceutical Preparations | Akkaraju Srinivas | CA | D |  | P | 7,000 | 12.25 | 3 | 571 | 999% | 583 | I | -37 | 8 | 45 | 15 | -7 | -4 | -6 | -1 | 0 | 1 | -12 | 23 | 75 |  | 
8/26/16 17:12  | 8/25/16  | VSAR | Health | Drug | Pharmaceutical Preparations | Varian John | CA | D |  | S | -21 | 12.97 | 1 | -2 | -17 | 8 | D | -43 | -6 | 89 | 43 | 20 | 11 | -3 | -4 | 3 | 4 | 0 | 5 | 82 |  | 
8/24/16 18:22  | 8/22/16  | VSAR | Health | Drug | Pharmaceutical Preparations | Shepard Jay | CA | DO | P,CEO | S | -70 | 12.88 | 1 | -5 | -3 | 155 | D | -32 | 1 | 95 | 44 | 24 | 16 | 3 | 1 | 0 | 4 | 3 | 3 | 64 |  | 
6/17/16 16:06  | 6/15/16  | VSAR | Health | Drug | Pharmaceutical Preparations | Brumm Joshua T | CA | O | CFO | S | -15 | 10.63 | 1 | -1 | -2 | 59 | D | -63 | -34 | -4 | 67 | 44 | 26 | 1 | -7 | 0 | 6 | 0 | 18 | 17 |  | 
6/17/16 16:05  | 6/15/16  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | S | -8 | 10.63 | 1 | -1 | -2 | 35 | D | -63 | -34 | -4 | 67 | 44 | 26 | 1 | -7 | 0 | 6 | 0 | 18 | 17 |  | 
5/20/16 19:18  | 5/20/16  | VSAR | Health | Drug | Pharmaceutical Preparations | Brumm Joshua T | CA | O | CFO | S | -10 | 7.87 | 1 | -1 | -2 | 60 | D | -72 | -47 | -22 | 5 | -13 | -13 | 0 | -1 | 8 | 8 | 36 | 63 | 57 |  | 
4/25/16 19:38  | 4/21/16  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | S | -14 | 9.68 | 1 | -1 | -4 | 36 | D | -66 | -44 | 1 | -27 | 47 | 25 | 7 | 4 | -3 | -10 | -13 | 11 | 20 |  | 
1/4/16 18:58  | 12/30/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | S | -5 | 12.44 | 1 | 0 | -2 | 20 | D |  | -45 | -15 | 12 | 19 | 4 | 12 | -1 | 0 | -16 | -15 | -31 | -9 | 24 | 
1/4/16 18:56  | 12/30/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Brumm Joshua T | CA | O | CFO | S | -12 | 12.44 | 1 | -1 | -3 | 36 | D |  | -45 | -15 | 12 | 19 | 4 | 12 | -1 | 0 | -16 | -15 | -31 | -9 | 24 | 
11/13/15 17:37  | 11/12/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Brumm Joshua T | CA | O | CFO | P | 25 | 9.99 | 2 | 3 | 7 | 37 | D |  | -49 | -34 | -41 | -13 | -11 | -11 | -7 | 1 | 2 | 8 | -22 | -24 | 24 | 
11/13/15 17:34  | 11/11/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Greer R Scott | CA | D |  | P | 102 | 10.17 | 2 | 10 | 66 | 25 | D |  | -49 | -34 | -41 | -13 | -11 | -11 | -7 | 1 | 2 | 8 | -22 | -24 | 24 | 
8/5/15 17:59  | 8/4/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | M.d | 3 | 1.27 | 3 | 2 | 13 | 21 | D |  | -13 | 3 | 8 | 11 | -4 | 2 | 5 | -1 | -7 | -37 | -42 | -52 | -43 | 
8/5/15 17:59  | 8/4/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | S.d | -44 | 18.27 | 3 | -2 | -10 | 21 | D |  | -13 | 3 | 8 | 11 | -4 | 2 | 5 | -1 | -7 | -37 | -42 | -52 | -43 | 
7/7/15 18:53  | 7/6/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | M.d | 3 | 1.27 | 6 | 2 | 13 | 21 | D |  | -34 | -15 | 8 | 28 | 4 | 15 | 24 | -4 | 4 | 0 | -39 | -35 | -43 | 
7/7/15 18:53  | 7/6/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | S.d | -36 | 15.00 | 6 | -2 | -10 | 21 | D |  | -34 | -15 | 8 | 28 | 4 | 15 | 24 | -4 | 4 | 0 | -39 | -35 | -43 | 
6/4/15 18:14  | 6/3/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | M.d | 3 | 1.27 | 4 | 2 | 12 | 22 | D |  | -44 | -7 | -21 | -7 | 13 | 15 | 9 | 4 | 3 | -12 | -25 | -24 | -39 | 
6/4/15 18:14  | 6/3/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | S.d | -40 | 16.73 | 4 | -2 | -10 | 22 | D |  | -44 | -7 | -21 | -7 | 13 | 15 | 9 | 4 | 3 | -12 | -25 | -24 | -39 | 
5/6/15 18:25  | 5/4/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | M.d | 3 | 1.27 | 2 | 2 | 12 | 22 | D |  | -40 | -14 | -5 | -17 | -13 | -7 | 1 | -11 | -12 | -4 | 8 | -35 | -57 | 
5/6/15 18:25  | 5/4/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | S.d | -42 | 17.47 | 2 | -2 | -10 | 22 | D |  | -40 | -14 | -5 | -17 | -13 | -7 | 1 | -11 | -12 | -4 | 8 | -35 | -57 | 
4/16/15 21:26  | 4/14/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Cleland Jeffrey L | CA | DO | P,CEO | S | -161 | 20.13 | 2 | -8 | -6 | 122 | D |  | -19 | -2 | -11 | -7 | 0 | 14 | 9 | -2 | -6 | -22 | 1 | -48 | -50 | 
4/16/15 21:25  | 12/19/14  | VSAR | Health | Drug | Pharmaceutical Preparations | Cleland Jeffrey L | CA | DO | P,CEO | S.am | -169 | 21.14 | 2 | -8 | -6 | 133 | D |  | -19 | -2 | -11 | -7 | 0 | 14 | 9 | -2 | -6 | -22 | 1 | -48 | -50 | 
4/8/15 19:58  | 4/6/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | M.d | 3 | 1.27 | 2 | 2 | 12 | 22 | D |  | -33 | -8 | -22 | -9 | -8 | -8 | 0 | -1 | 5 | -6 | 2 | -40 | -49 | 
4/8/15 19:58  | 4/6/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | S.d | -42 | 17.49 | 2 | -2 | -10 | 22 | D |  | -33 | -8 | -22 | -9 | -8 | -8 | 0 | -1 | 5 | -6 | 2 | -40 | -49 | 
3/24/15 16:33  | 3/23/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Cleland Jeffrey L | CA | DO | P,CEO | S | -81 | 20.26 | 1 | -4 | -4 | 93 | D |  | -36 | -2 | 5 | 17 | 0 | 0 | 1 | -4 | -9 | -12 | -19 | -41 | -68 | 
3/20/15 19:49  | 3/18/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Cleland Jeffrey L | CA | DO | P,CEO | S.m | -64 | 20.03 | 1 | -3 | -3 | 97 | D |  |  | -7 | 4 | 13 | 1 | 0 | 2 | -1 | -2 | -8 | -19 | -47 | -67 | 
3/17/15 18:16  | 3/16/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Cleland Jeffrey L | CA | DO | P,CEO | S.m | -16 | 20.08 | 1 | -1 | -1 | 101 | D |  |  | -1 | 6 | 12 | -2 | -9 | -2 | -1 | 1 | 0 | -9 | -35 | -69 | 
3/11/15 16:37  | 3/9/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Cleland Jeffrey L | CA | DO | P,CEO | S.m | -81 | 20.23 | 1 | -4 | -4 | 101 | D |  |  | -5 | 14 | 8 | 11 | 1 | -7 | 0 | 0 | -9 | -16 | -37 | -66 | 
3/5/15 16:40  | 3/3/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | M.d | 3 | 1.27 | 2 | 2 | 12 | 22 | D |  |  | -8 | 17 | 24 | 15 | 10 | 8 | -5 | -7 | -17 | -21 | -42 | -64 | 
3/5/15 16:40  | 3/3/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | S.d | -48 | 20.03 | 2 | -2 | -10 | 22 | D |  |  | -8 | 17 | 24 | 15 | 10 | 8 | -5 | -7 | -17 | -21 | -42 | -64 | 
3/5/15 16:39  | 3/3/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Cleland Jeffrey L | CA | DO | P,CEO | S | -23 | 20.07 | 2 | -1 | -1 | 105 | D |  |  | -8 | 17 | 24 | 15 | 10 | 8 | -5 | -7 | -17 | -21 | -42 | -64 | 
3/2/15 21:05  | 3/2/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Cleland Jeffrey L | CA | DO | P,CEO | S | -58 | 20.11 | 2 | -3 | -3 | 107 | D |  |  | -13 | 8 | 4 | 14 | 10 | -1 | -1 | 1 | -7 | -24 | -36 | -69 | 
2/27/15 17:38  | 2/25/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Cleland Jeffrey L | CA | DO | P,CEO | S | -162 | 20.25 | 2 | -8 | -7 | 109 | D |  |  | -7 | 12 | -2 | 16 | 17 | 5 | 2 | 8 | -3 | -20 | -32 | -65 | 
2/4/15 20:14  | 2/3/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | M.d | 6 | 1.27 | 4 | 5 | 29 | 22 | D |  |  | -15 | -9 | -9 | -19 | 5 | -2 | 3 | 3 | 24 | 1 | 9 | -42 | 
2/4/15 20:14  | 2/3/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | S.d | -87 | 17.40 | 4 | -5 | -18 | 22 | D |  |  | -15 | -9 | -9 | -19 | 5 | -2 | 3 | 3 | 24 | 1 | 9 | -42 | 
1/29/15 17:10  | 1/27/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Aisling Capital III LP | NY | T |  | P | 2,501 | 17.25 | 4 | 145 | 7 | 2,140 | I |  |  | -14 | -6 | -4 | -16 | -3 | 6 | -4 | -8 | 7 | -6 | -2 | -43 | 
1/29/15 17:09  | 1/27/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Sun Anthony Y | NY | D |  | P | 2,501 | 17.25 | 4 | 145 | 7 | 2,140 | I |  |  | -14 | -6 | -4 | -16 | -3 | 6 | -4 | -8 | 7 | -6 | -2 | -43 | 
1/27/15 19:24  | 1/27/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Greer R Scott | CA | D |  | P | 95 | 17.25 | 4 | 6 | 110 | 11 | D |  |  | -17 | -7 | -1 | -22 | -12 | 5 | -1 | -6 | 11 | -8 | 1 | -32 | 
1/26/15 17:31  | 1/22/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Advent Life Sciences LLP | X0 | H | Affiliat | P.ad | 949 | 17.25 | 3 | 55 | 2 | 2,272 | I |  |  | -21 | -11 | -7 | -23 | -23 | -11 | 2 | -3 | 10 | 2 | 1 | -25 | 
1/26/15 17:13  | 1/22/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Malik Shahzad | X0 | D |  | P.d | 949 | 17.25 | 3 | 55 | 2 | 2,272 | I |  |  | -21 | -11 | -7 | -23 | -23 | -11 | 2 | -3 | 10 | 2 | 1 | -25 | 
1/26/15 16:59  | 1/22/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Advent Life Sciences LLP | X0 | H | Affiliat | P.d | 949 | 17.25 | 3 | 55 | 2 | 2,272 | I |  |  | -21 | -11 | -7 | -23 | -23 | -11 | 2 | -3 | 10 | 2 | 1 | -25 | 
1/13/15 17:54  | 1/12/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Cleland Jeffrey L | CA | DO | P,CEO | S | -91 | 22.85 | 4 | -4 | -3 | 117 | D |  |  | -19 | 16 | 27 | 15 | 2 | 5 | -8 | -14 | -17 | -15 | -15 | -57 | 
1/7/15 17:26  | 1/5/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | M.d | 6 | 1.27 | 3 | 5 | 29 | 22 | D |  |  | -22 | 9 | 22 | 15 | -1 | -2 | 2 | 2 | -20 | -16 | -19 | -51 | 
1/7/15 17:26  | 1/5/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | S.d | -112 | 22.48 | 3 | -5 | -18 | 22 | D |  |  | -22 | 9 | 22 | 15 | -1 | -2 | 2 | 2 | -20 | -16 | -19 | -51 | 
1/7/15 17:14  | 1/5/15  | VSAR | Health | Drug | Pharmaceutical Preparations | Cleland Jeffrey L | CA | DO | P,CEO | S | -88 | 21.94 | 3 | -4 | -3 | 121 | D |  |  | -22 | 9 | 22 | 15 | -1 | -2 | 2 | 2 | -20 | -16 | -19 | -51 | 
12/30/14 16:56  | 12/29/14  | VSAR | Health | Drug | Pharmaceutical Preparations | Cleland Jeffrey L | CA | DO | P,CEO | S.d | -88 | 22.11 | 3 | -4 | -3 | 125 | D |  |  | -22 | 12 | 19 | 19 | 15 | -2 | 6 | 3 | -12 | -13 | -27 | -39 | 
12/22/14 20:09  | 12/19/14  | VSAR | Health | Drug | Pharmaceutical Preparations | Cleland Jeffrey L | CA | DO | P,CEO | S.m | -169 | 21.14 | 2 | -8 | -8 | 97 | D |  |  | -31 | 0 | 2 | 9 | 7 | 4 | -3 | -5 | -27 | -11 | -31 | -60 | 
12/22/14 18:41  | 12/18/14  | VSAR | Health | Drug | Pharmaceutical Preparations | New Leaf Ventures Ii, L.P. | NY | T |  | S | -2,852 | 19.01 | 2 | -150 | -6 | 2,409 | D |  |  | -31 | 0 | 2 | 9 | 7 | 4 | -3 | -5 | -27 | -11 | -31 | -60 | 
12/15/14 16:22  | 12/11/14  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | M.dm | 13 | 1.27 | 2 | 10 | 115 | 19 | D |  |  | -41 | -3 | -6 | 4 | 6 | 0 | 1 | 4 | 9 | 5 | -8 | -43 | 
12/15/14 16:22  | 12/11/14  | VSAR | Health | Drug | Pharmaceutical Preparations | Westberg Paul | CA | O | SVP,Busi | S.dm | -186 | 18.55 | 2 | -10 | -35 | 19 | D |  |  | -41 | -3 | -6 | 4 | 6 | 0 | 1 | 4 | 9 | 5 | -8 | -43 | 
11/25/14 18:55  | 11/24/14  | VSAR | Health | Drug | Pharmaceutical Preparations | Index Ventures IV (Jersey) LP | Y9 | T |  | S | -310 | 18.02 | 3 | -17 | -47 | 19 | D |  |  | -33 | -17 | -14 | -3 | -5 | -1 | 0 | 0 | 21 | 11 | -14 | -37 | 
11/24/14 12:11  | 11/21/14  | VSAR | Health | Drug | Pharmaceutical Preparations | Index Ventures IV (Jersey) LP | Y9 | T |  | S | -483 | 18.04 | 3 | -27 | -58 | 19 | D |  |  | -36 | -10 | -12 | -4 | -8 | -8 | 1 | 2 | 25 | 15 | -16 | -35 | 
11/21/14 14:48  | 11/20/14  | VSAR | Health | Drug | Pharmaceutical Preparations | Index Ventures IV (Jersey) LP | Y9 | T |  | S | -165 | 18.32 | 3 | -9 | -32 | 20 | D |  |  | -34 | -5 | -7 | -8 | -5 | -2 | -3 | -2 | 25 | 8 | -21 | -42 | 
11/20/14 11:59  | 11/18/14  | VSAR | Health | Drug | Pharmaceutical Preparations | Index Ventures IV (Jersey) LP | Y9 | T |  | S | -3,709 | 19.38 | 3 | -191 | -91 | 20 | D |  |  | -35 | -8 | -8 | -9 | -5 | -1 | 1 | 0 | 9 | 6 | -19 | -43 | 
11/17/14 13:39  | 11/13/14  | VSAR | Health | Drug | Pharmaceutical Preparations | Index Ventures IV (Jersey) LP | Y9 | T |  | S | -242 | 19.43 | 2 | -12 | -37 | 21 | D |  |  | -32 | -9 | -8 | -5 | -5 | -5 | 1 | -3 | 3 | -3 | -19 | -44 | 
11/14/14 11:44  | 11/12/14  | VSAR | Health | Drug | Pharmaceutical Preparations | Index Ventures IV (Jersey) LP | Y9 | T |  | S | -703 | 19.42 | 2 | -36 | -63 | 21 | D |  |  | -30 | -1 | -3 | -2 | 3 | -1 | -3 | -4 | -1 | -9 | -21 | -47 | 
11/13/14 18:38  | 11/11/14  | VSAR | Health | Drug | Pharmaceutical Preparations | New Leaf Ventures Ii, L.P. | NY | T |  | S | -15,496 | 19.37 | 2 | -800 | -24 | 2,559 | D |  |  | -29 | 2 | 1 | 0 | 4 | 0 | -3 | -4 | -2 | -6 | -21 | -48 | 
10/1/14 17:09  | 9/29/14  | VSAR | Health | Drug | Pharmaceutical Preparations | New Leaf Ventures Ii, L.P. | NY | T |  | S | -251 | 20.02 | 1 | -13 | 0 | 3,359 | D |  |  | -37 | -34 | -4 | -6 | -7 | -6 | 2 | 1 | 1 | 11 | -4 | -39 | 
3/28/14 19:30  | 3/27/14  | VSAR | Health | Drug | Pharmaceutical Preparations | New Leaf Ventures Ii, L.P. | NY | DT |  | P.d | 1,261 | 21.02 | 33 | 60 | 2 | 3,372 | D |  |  |  |  |  |  |  | 1 | 0 | -5 | -1 | -7 | -33 | -36 | 
3/28/14 18:46  | 3/26/14  | VSAR | Health | Drug | Pharmaceutical Preparations | Akkaraju Srinivas | CA | DT |  | P.d | 1,260 | 21.00 | 33 | 60 | 3 | 2,147 | D |  |  |  |  |  |  |  | 1 | 0 | -5 | -1 | -7 | -33 | -36 | 
3/27/14 18:36  | 3/26/14  | VSAR | Health | Drug | Pharmaceutical Preparations | Sun Anthony Y | NY | DT |  | P.d | 1,260 | 21.00 | 33 | 60 | 3 | 1,995 | I |  |  |  |  |  |  |  | -2 | 0 | 0 | 0 | -7 | -32 | -33 | 
3/27/14 18:34  | 3/26/14  | VSAR | Health | Drug | Pharmaceutical Preparations | Aisling Capital III LP | NY | T |  | P.d | 1,260 | 21.00 | 33 | 60 | 3 | 1,995 | I |  |  |  |  |  |  |  | -2 | 0 | 0 | 0 | -7 | -32 | -33 | 
3/27/14 17:12  | 3/26/14  | VSAR | Health | Drug | Pharmaceutical Preparations | Malik Shahzad | X0 | DT |  | P.d | 1,260 | 21.00 | 33 | 60 | 3 | 2,217 | I |  |  |  |  |  |  |  | -2 | 0 | 0 | 0 | -7 | -32 | -33 | 
3/27/14 17:10  | 3/26/14  | VSAR | Health | Drug | Pharmaceutical Preparations | Advent Life Sciences LLP | X0 | T |  | P.d | 1,260 | 21.00 | 33 | 60 | 3 | 2,217 | I |  |  |  |  |  |  |  | -2 | 0 | 0 | 0 | -7 | -32 | -33 |