OPK - Opko Health, Inc. - Insider Stock Trading

Filing Date	T Date	Ticker	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
10/31/25 17:15	10/31/25	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	213	1.42	150	0	248,083	I
8/8/25 16:56	8/8/25	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	891	1.32	675	0	248,373	I
4/10/25 17:07	4/10/25	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	170	1.36	125	0	247,698	I
4/8/25 17:34	4/8/25	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	185	1.48	125	0	247,573	I
4/1/25 17:21	4/1/25	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	165	1.65	100	0	247,448	I
3/28/25 17:22	3/28/25	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	254	1.70	150	0	247,348	I
3/17/25 17:27	3/17/25	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	348	1.74	200	0	247,198	I
2/28/25 19:34	2/28/25	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P.d	115	1.71	67	0	246,998	I
1/28/25 17:40	1/28/25	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	70	1.47	48	0	246,930	I
1/17/25 17:06	1/17/25	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	220	1.47	150	0	246,883	I
1/15/25 17:18	1/15/25	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	741	1.48	500	0	246,733	I
12/13/24 17:04	12/13/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	199	1.60	125	0	246,233	I
12/11/24 17:21	12/11/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	781	1.56	500	0	246,108	I
11/29/24 15:20	11/29/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	305	1.53	199	0	245,608	I
11/22/24 17:17	11/22/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	159	1.59	100	0	245,409	I
11/20/24 19:21	11/8/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P.a	422	1.50	280	0	245,209	I
11/14/24 17:51	11/14/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	162	1.62	100	0	245,309	I
11/8/24 17:40	11/8/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	422	1.50	280	0	244,709	I
5/23/24 20:04	5/23/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	127	1.27	100	0	244,428	I
5/17/24 17:31	5/17/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	211	1.29	164	0	244,328	I
3/18/24 16:45	3/18/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	437	0.8742	500	0	244,164	I
3/14/24 17:00	3/14/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	444	0.8886	500	0	243,664	I
3/13/24 16:44	3/13/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	464	0.9275	500	0	243,164	I
3/12/24 17:27	3/12/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	559	0.9323	600	0	242,664	I
2/28/24 17:31	2/28/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	496	0.9923	500	0	242,064	I
2/21/24 17:10	2/21/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	992	0.9917	1,000	0	241,564	I
2/7/24 17:09	2/7/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	1,463	0.9752	1,500	1	240,564	I
1/29/24 15:30	1/29/24	OPK	Health	Drug	Pharmaceutical Preparations	Krasno Richard M	FL	D		P	30	0.9946	30	41	103	I
1/19/24 16:54	1/19/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	489	0.9773	500	0	239,064	I
1/18/24 17:06	1/18/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	386	0.9655	400	0	238,564	I
1/17/24 17:09	1/17/24	OPK	Health	Drug	Pharmaceutical Preparations	Hsiao Jane Ph D	FL	DO	Vice CB,	P	143	0.9500	150	0	33,127	D
1/16/24 17:03	1/16/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	954	0.9543	1,000	0	238,164	I
1/11/24 17:15	1/11/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	480	0.9391	512	0	237,164	I
1/10/24 17:56	1/8/24	OPK	Health	Drug	Pharmaceutical Preparations	Nabel Gary J.	FL	DO	Chief In	P	200	0.9271	216	1	40,547	I
1/8/24 09:10	1/5/24	OPK	Health	Drug	Pharmaceutical Preparations	Hsiao Jane Ph D	FL	DO	Vice CB,	P.d	131	0.8726	150	0	32,977	D
1/8/24 08:54	1/5/24	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P.d	1,345	0.8964	1,500	1	236,653	I
1/5/24 17:26	1/5/24	OPK	Health	Drug	Pharmaceutical Preparations	Zerhouni Elias A.	FL	DO	Vice CB,	P	514	0.9342	550	1	40,195	I
1/5/24 16:00	1/5/24	OPK	Health	Drug	Pharmaceutical Preparations	Paganelli John A	FL	D		P	22	0.8832	25	7	394	D
1/5/24 13:39	1/5/24	OPK	Health	Drug	Pharmaceutical Preparations	Rubin Steven D	FL	DO	EVP-Admi	P	9	0.8669	10	0	6,188	D
1/5/24 12:42	1/5/24	OPK	Health	Drug	Pharmaceutical Preparations	Pfenniger Richard C Jr	FL	D		P	23	0.9372	25	8	325	D
11/13/23 08:23	11/9/23	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P.m	1,267	1.27	1,000	0	235,153	I
11/13/23 08:21	11/10/23	OPK	Health	Drug	Pharmaceutical Preparations	Hsiao Jane Ph D	FL	DO	Vice CB,	P	127	1.27	100	0	32,827	D
11/13/23 08:21	11/10/23	OPK	Health	Drug	Pharmaceutical Preparations	Rubin Steven D	FL	DO	EVP-Admi	P	13	1.30	10	0	6,178	D
8/18/23 07:10	8/17/23	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	176	1.76	100	0	234,153	I
8/15/23 07:05	8/14/23	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	131	1.75	75	0	234,053	I
8/10/23 06:59	8/9/23	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	182	1.82	100	0	233,978	I
8/8/23 07:07	8/7/23	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	1,195	1.84	650	0	233,878	I
5/8/23 07:03	5/5/23	OPK	Health	Drug	Pharmaceutical Preparations	Nabel Gary J.	FL	DO	Chief In	P	841	1.83	460	999%	506	M
3/23/23 06:52	3/22/23	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	264	1.32	200	0	233,228	I
3/9/23 06:26	3/8/23	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	1,175	1.18	1,000	0	233,028	I
11/23/22 07:10	11/22/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	447	1.49	300	0	232,028	I
11/10/22 06:56	11/9/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	319	1.60	200	0	430,160	I
10/28/22 06:49	10/27/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	182	1.82	100	0	231,528	I
10/20/22 06:24	10/19/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	172	1.72	100	0	231,428	I
10/17/22 07:14	10/14/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	172	1.72	100	0	231,328	I
10/14/22 06:57	10/13/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	179	1.79	100	0	231,228	I
10/13/22 07:43	10/12/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	173	1.73	100	0	231,128	I
10/11/22 07:47	10/7/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	133	1.77	75	0	231,028	I
9/27/22 07:29	9/26/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	90	1.80	50	0	230,953	I
9/26/22 06:59	9/23/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	92	1.85	50	0	230,903	I
9/23/22 07:20	9/22/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	95	1.90	50	0	230,853	I
9/22/22 07:39	9/21/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	95	1.91	50	0	230,803	I
9/21/22 07:23	9/20/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	97	1.94	50	0	230,753	I
9/20/22 07:20	9/19/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	99	1.97	50	0	230,703	I
9/16/22 07:42	9/15/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	413	2.06	200	0	230,653	I
9/6/22 07:50	9/2/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	214	2.14	100	0	230,453	I
8/18/22 08:22	8/17/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	508	2.54	200	0	230,353	I
8/8/22 08:05	8/5/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	802	2.29	350	0	230,153	I
6/24/22 19:52	6/22/22	OPK	Health	Drug	Pharmaceutical Preparations	Nabel Gary J.	FL	DO	Chief In	P	597	2.49	240	1	39,870	I
6/22/22 06:59	6/21/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	479	2.39	200	0	229,803	I
6/17/22 08:11	6/16/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	231	2.31	100	0	229,603	I
6/14/22 08:05	6/13/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	236	2.36	100	0	229,503	I
6/7/22 07:29	6/6/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	279	2.79	100	0	229,403	I
6/2/22 08:08	6/1/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	148	2.95	50	0	229,303	I
6/1/22 07:28	5/31/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	151	3.02	50	0	229,253	I
5/26/22 08:16	5/25/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	149	2.98	50	0	229,203	I
5/19/22 16:28	5/12/22	OPK	Health	Drug	Pharmaceutical Preparations	Nabel Gary J.	FL	DO	Chief In	P.m	217	2.88	75	New	75	D
5/19/22 07:32	5/18/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	144	2.88	50	0	229,153	I
5/17/22 06:33	5/16/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	447	2.98	150	0	229,103	I
5/16/22 07:17	5/13/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	599	3.00	200	0	228,953	I
5/12/22 06:50	5/11/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	1,132	2.83	400	0	228,753	I
5/11/22 21:01	5/10/22	OPK	Health	Drug	Pharmaceutical Preparations	Zerhouni Elias A.	FL	DO	Vice CB,	P.d	250	2.79	90	New	90	D
5/11/22 06:49	5/10/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	1,114	2.78	400	0	228,353	I
3/15/22 07:33	3/14/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	106	3.04	35	0	227,953	I
3/14/22 07:16	3/11/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	313	3.13	100	0	227,918	I
3/1/22 07:33	2/28/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	311	3.11	100	0	227,818	I
2/28/22 07:59	2/25/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	2,315	3.09	750	0	227,718	I
2/15/22 09:10	2/14/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	304	3.04	100	0	226,968	I
2/2/22 07:18	2/1/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	455	3.03	150	0	226,868	I
1/27/22 08:12	1/26/22	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	1,042	2.98	350	0	226,718	I
9/15/21 07:09	9/14/21	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	346	3.46	100	0	226,368	I
8/16/21 08:33	8/13/21	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	369	3.69	100	0	226,268	I
8/10/21 16:12	8/9/21	OPK	Health	Drug	Pharmaceutical Preparations	Hsiao Jane Ph D	FL	DO	Vice CB,	P	0	3.73	0	0	27,600	D
6/15/21 07:24	6/14/21	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	724	3.62	200	0	226,168	I
6/1/21 14:41	5/10/21	OPK	Health	Drug	Pharmaceutical Preparations	Cohen Jon R	FL	DO	SVP OPKO	P	191	3.81	50	67	125	D
5/26/21 07:42	5/25/21	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	1,456	3.64	400	0	225,968	I
5/11/21 07:36	5/10/21	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	274	3.65	75	0	225,568	I
5/10/21 07:25	5/7/21	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	288	3.84	75	0	225,493	I
5/7/21 07:04	5/6/21	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	98	3.91	25	0	225,418	I
5/5/21 07:59	5/4/21	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	98	3.94	25	0	225,393	I
3/8/21 07:20	3/5/21	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	1,174	3.91	300	0	225,368	I
2/22/21 07:37	2/19/21	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P.d	2,383	4.77	500	0	225,068	I
1/26/21 16:07	1/25/21	OPK	Health	Drug	Pharmaceutical Preparations	Fishel Robert Scott	FL	D		M.d	162	2.70	60	1	4,181	D
12/29/20 07:33	12/28/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	1,200	4.00	300	0	224,568	I
11/10/20 06:53	11/9/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	795	3.18	250	0	224,268	I
11/2/20 06:57	10/30/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	2,073	3.45	600	0	224,018	I
8/27/20 08:40	8/26/20	OPK	Health	Drug	Pharmaceutical Preparations	Rubin Steven D	FL	DO	EVP-Admi	P	40	3.99	10	0	6,168	D
6/4/20 07:26	6/3/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	227	2.27	100	0	223,418	I
6/3/20 07:54	6/2/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	242	2.42	100	0	223,318	I
5/29/20 07:21	5/28/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	216	2.16	100	0	223,218	I
5/27/20 08:03	5/26/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	588	2.35	250	0	223,118	I
5/8/20 07:45	5/7/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	832	2.08	400	0	222,868	I
4/20/20 08:06	4/17/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	540	1.66	325	0	222,468	I
4/17/20 08:02	4/16/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	41	1.63	25	0	222,143	I
4/16/20 08:20	4/15/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	309	1.55	200	0	222,118	I
4/8/20 08:02	4/7/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	511	1.28	400	0	221,918	I
4/6/20 08:18	4/3/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	58	1.15	50	0	221,518	I
4/3/20 07:41	4/2/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	581	1.16	500	0	221,468	I
4/2/20 08:12	4/1/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	793	1.23	644	0	220,968	I
3/31/20 08:06	3/30/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	218	1.35	162	0	220,324	I
3/30/20 08:00	3/27/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	140	1.40	100	0	220,162	I
3/27/20 08:01	3/26/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	275	1.38	200	0	220,062	I
3/20/20 07:44	3/19/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	149	1.49	100	0	219,862	I
3/13/20 06:03	3/12/20	OPK	Health	Drug	Pharmaceutical Preparations	Japour Anthony J	FL	D		P	1	1.51	1	100	1	D
3/11/20 09:45	3/10/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	482	1.61	300	0	219,762	I
3/4/20 13:51	3/3/20	OPK	Health	Drug	Pharmaceutical Preparations	Japour Anthony J	FL	D		P	1	1.47	1	New	1	D
3/4/20 06:01	3/3/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	147	1.47	100	0	223,318	I
3/3/20 06:04	3/2/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	149	1.49	100	0	223,218	I
3/2/20 06:47	2/28/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	182	1.46	125	0	223,118	I
2/28/20 06:07	2/27/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	370	1.48	250	0	222,993	I
2/18/20 06:04	2/14/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	157	1.57	100	0	222,743	I
2/14/20 06:06	2/13/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	158	1.58	100	0	222,643	I
2/12/20 06:07	2/11/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	23	1.59	14	0	222,543	I
2/7/20 07:20	2/6/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	77	1.53	50	0	222,529	I
2/3/20 06:53	1/31/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	72	1.44	50	0	222,479	I
1/31/20 07:23	1/30/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	147	1.47	100	0	222,429	I
1/27/20 06:30	1/24/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	79	1.58	50	0	222,329	I
1/24/20 07:30	1/23/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	82	1.63	50	0	222,279	I
1/21/20 06:04	1/17/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	35	1.56	22	0	222,229	I
1/14/20 06:07	1/13/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	72	1.44	50	0	222,207	I
1/13/20 06:04	1/10/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	74	1.48	50	0	222,157	I
1/9/20 06:53	1/8/20	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	74	1.47	50	0	222,107	I
12/31/19 08:14	12/30/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	146	1.46	100	0	222,057	I
12/30/19 07:44	12/27/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	153	1.53	100	0	221,957	I
12/20/19 06:18	12/19/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	148	1.48	100	0	221,857	I
12/19/19 06:03	12/18/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	225	1.50	150	0	221,757	I
12/18/19 06:06	12/17/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	115	1.54	75	0	221,607	I
12/12/19 06:01	12/11/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	150	1.50	100	0	221,532	I
12/10/19 06:04	12/9/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	80	1.59	50	0	221,432	I
12/6/19 06:11	12/5/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	80	1.60	50	0	221,382	I
12/4/19 06:38	12/3/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	16	1.60	10	0	221,332	I
12/3/19 07:09	12/2/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	78	1.56	50	0	221,322	I
11/27/19 06:45	11/26/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	155	1.55	100	0	221,272	I
11/20/19 06:55	11/19/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	147	1.47	100	0	221,172	I
11/19/19 06:22	11/18/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	148	1.48	100	0	221,072	I
11/14/19 07:08	11/13/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	71	1.42	50	0	220,972	I
11/13/19 06:04	11/12/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	288	1.44	200	0	220,922	I
11/12/19 06:01	11/8/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	74	1.48	50	0	220,722	I
11/7/19 06:06	11/6/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	521	1.49	350	0	220,672	I
11/1/19 06:03	10/31/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	71	1.43	50	0	220,322	I
10/31/19 06:04	10/30/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	289	1.44	200	0	220,272	I
10/30/19 07:16	10/29/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	294	1.47	200	0	220,072	I
10/28/19 06:04	10/25/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	491	1.40	350	0	219,872	I
10/25/19 16:11	10/25/19	OPK	Health	Drug	Pharmaceutical Preparations	Pfenniger Richard C Jr	FL	D		P	36	1.45	25	10	275	D
10/25/19 14:46	10/25/19	OPK	Health	Drug	Pharmaceutical Preparations	Rubin Steven D	FL	DO	EVP-Admi	P	23	1.50	15	0	25,835	D
10/25/19 14:13	10/25/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	3,000	1.50	2,000	1	219,522	I
10/25/19 14:10	10/25/19	OPK	Health	Drug	Pharmaceutical Preparations	Hsiao Jane Ph D	FL	DO	Vice CB,	P	600	1.50	400	1	49,694	I
7/17/19 07:14	7/16/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	106	2.12	50	0	217,522	I
7/15/19 06:55	7/12/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	108	2.16	50	0	217,472	I
7/9/19 06:30	7/8/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	223	2.23	100	0	217,422	I
7/3/19 13:06	7/2/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P.d	121	2.42	50	0	217,322	I
6/26/19 06:43	6/25/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	201	2.01	100	0	217,272	I
6/21/19 07:10	6/20/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	102	2.04	50	0	217,172	I
6/20/19 06:28	6/19/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	50	2.01	25	0	217,122	I
6/19/19 06:08	6/18/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	101	2.02	50	0	217,097	I
6/17/19 06:46	6/14/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	134	1.91	70	0	217,047	I
6/14/19 06:09	6/13/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	96	1.92	50	0	216,977	I
6/13/19 07:32	6/12/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	27	1.83	15	0	216,927	I
6/12/19 06:57	6/11/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	93	1.87	50	0	216,912	I
6/10/19 06:10	6/7/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	94	1.87	50	0	216,862	I
6/7/19 07:03	6/6/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	48	1.92	25	0	216,812	I
6/6/19 06:05	6/5/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	288	1.92	150	0	216,787	I
6/3/19 06:03	5/31/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	176	1.76	100	0	216,637	I
5/31/19 06:07	5/30/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	93	1.86	50	0	216,537	I
5/30/19 06:49	5/29/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	129	1.84	70	0	216,487	I
5/29/19 06:15	5/28/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	380	1.90	200	0	216,417	I
5/29/19 06:10	5/28/19	OPK	Health	Drug	Pharmaceutical Preparations	Fishel Robert Scott	FL	D		P	96	1.92	50	1	4,121	I
5/24/19 06:53	5/23/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	384	1.92	200	0	216,217	I
5/23/19 06:04	5/22/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	250	2.00	125	0	216,017	I
5/23/19 06:02	5/22/19	OPK	Health	Drug	Pharmaceutical Preparations	Pfenniger Richard C Jr	FL	D		P	62	2.05	30	14	250	D
5/20/19 06:03	5/17/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	104	2.08	50	0	215,892	I
5/17/19 06:01	5/16/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	202	2.02	100	0	215,842	I
5/15/19 06:04	5/14/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	1,995	2.00	1,000	0	215,742	I
5/14/19 06:05	5/13/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	398	1.99	200	0	214,742	I
5/14/19 06:03	5/13/19	OPK	Health	Drug	Pharmaceutical Preparations	Pfenniger Richard C Jr	FL	D		P	102	2.05	50	29	220	D
5/13/19 06:02	5/10/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	146	2.08	70	0	214,542	I
5/10/19 06:19	5/9/19	OPK	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	586	2.06	285	0	214,472	I
5/10/19 06:17	5/9/19	OPK	Health	Drug	Pharmaceutical Preparations	Hsiao Jane Ph D	FL	DO	Vice CB,	P	20	2.03	10	0	49,294	D
5/10/19 06:16	5/9/19	OPK	Health	Drug	Pharmaceutical Preparations	Rubin Steven D	FL	DO	EVP-Admi	P	21	2.14	10	0	25,820	D
5/10/19 06:13	5/9/19	OPK	Health	Drug	Pharmaceutical Preparations	Logal Adam	FL	O	SVP,CFO	P	7	2.04	3	2	179	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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