Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
8/1/25 17:09	8/1/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Van Houte Hans	CA	O	CFO	14	S.d	-1,586	18.93	-84		72	D
8/1/25 16:32	7/30/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		3	S.m	-3,175	61.03	-52		1,148	I
8/1/25 16:30	7/30/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	DT		4	S.dm	-634	2.59	-245		96	I
8/1/25 16:30	7/30/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	13	S.dm	-7,964	77.31	-103		48	D
8/1/25 16:06	7/30/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	9	S.ad	-5,526	38.45	-144		220	D
7/31/25 17:05	7/29/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Lai	V8	O	Global H	9	S.m	-5,490	244.21	-22		1,797	I
7/31/25 17:04	7/30/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	8	S	-1,702	245.87	-7		278	D
7/31/25 16:38	7/29/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	27	S.d	-12,606	46.80	-269		443	D
7/30/25 20:12	7/28/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levy Adam Scott	PA	O	CFO,Secr	7	S.m	-3,001	13.38	-224		255	D
7/30/25 18:49	7/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ring Christine	CA	O	GC	21	S.d	-1,922	21.32	-90		44	D
7/30/25 18:48	7/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hansen Gwenn	CA	O	Chief Sc	6	S.d	-342	16.91	-20		69	D
7/30/25 17:57	7/28/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	29	S.dm	-2,542	23.52	-108		23	D
7/30/25 17:00	7/29/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	2	S.d	-337	14.44	-23		216	D
7/30/25 16:56	7/29/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Poulton Stuart	MA	O	EVP,Chie	4	S	-30	2.39	-13		327	D
7/30/25 16:31	7/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	19	S.d	-381	13.95	-27		194	D
7/30/25 16:30	7/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Boyle Dana	NC	O	Chief Ac	2	S	-38	16.76	-2		187	D
7/30/25 16:03	7/28/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Smith Jason Drew	NJ	O	GC	3	S.d	-246	14.98	-16		41	D
7/30/25 16:02	7/28/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Schoenberg Mark	NJ	O	Chief Me	6	S.d	-435	13.22	-33		158	D
7/30/25 13:47	7/29/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	6	S.d	-207	5.65	-37	-100	0	D
7/29/25 18:56	7/29/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	14	S.dm	-7,507	54.76	-137		32	D
7/29/25 16:52	7/25/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stauderman Kenneth A.	CA	O	Chief Sc	1	S	-4	3.65	-1		13	M
7/28/25 18:08	7/25/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Patel Dinesh V Ph D	CA	DO	P,CEO	6	S.dm	-10,275	45.02	-228		550	D
7/25/25 19:06	7/23/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tahir Misbah	CA	O	CFO	6	S	-64	2.85	-22		188	D
7/25/25 19:03	7/23/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harler Mary Beth	CA	DO	CEO	6	S	-71	2.53	-28		347	D
7/25/25 19:01	7/23/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Decker Lisa Lynn	CA	O	CHIEF BU	6	S	-38	2.99	-13		79	D
7/25/25 18:56	7/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	13	S.d	-37,918	299.98	-126		37	D
7/25/25 18:24	7/25/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Weinhoff Gregory M	X0	O	Chief Bu	14	S.dm	-3,155	15.14	-208		223	D
7/25/25 16:00	7/24/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		35	S.e	-2,748,244	869.19	-3,162		98,713	D
7/24/25 17:00	7/22/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Mandalam Ramkumar	TN	D		7	S.dm	-639	7.51	-85		92	D
7/23/25 21:00	7/21/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	13	S.dm	-38,101	11.08	-3,440		1,462	D
7/23/25 18:52	7/21/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	19	S.dm	-5,426	23.56	-230		1,117	I
7/23/25 18:09	7/22/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peters Malte	NY	DO	CEO	1	S	-27	0.9200	-29		80	D
7/23/25 18:07	7/22/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Coelho Mary Theresa	NY	DO	EVP,CFO	1	S	-13	0.9200	-14		56	D
7/23/25 17:18	7/22/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Abate Kristin	MA	O	Chief Ac	2	S	-5	5.62	-1		10	D
7/23/25 17:00	7/22/25	MURA	Mural Oncology Plc	L2	Health	Drug	Pharmaceutical Preparations	Keson-Brookes Maiken	L2	O	See Rema	5	S.dm	-37	3.02	-12		74	D
7/23/25 16:35	7/21/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	12	S.dm	-41,354	72.91	-567		156	D
7/23/25 16:30	7/21/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	14	S.d	-688	13.99	-49		273	D
7/23/25 16:16	7/21/25	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Happel David	CA	DO	P,CEO	1	S	-598	9.13	-65		690	D
7/23/25 16:15	7/21/25	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Martins Eduardo Bruno	CA	O	Chief Me	2	S	-102	6.10	-17		107	D
7/23/25 16:14	7/21/25	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rozek Elizabeth	CA	O	GC,CCO	2	S	-132	6.10	-22		184	D
7/23/25 11:01	7/22/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	33	S.d	-10,726	55.56	-193		141	D
7/22/25 19:51	7/18/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cesano Alessandra	CA	D		2	S	-132	3.38	-39		69	D
7/22/25 17:08	7/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taub Rebecca	PA	D		6	S.dm	-29,988	275.11	-109		1,117	D
7/22/25 17:06	7/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedman Paul A	PA	D		4	S.dm	-35,141	269.74	-130		843	D
7/22/25 16:15	7/22/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vazzano Joseph Walter	OH	O	CFO	3	S	-279	6.24	-45		491	D
7/21/25 19:39	7/21/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Saha Saurabh	X0	DO	CEO	17	S.dm	-15,142	15.77	-960		862	D
7/21/25 19:21	7/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	19	S.dm	-5,361	23.23	-231		1,265	I
7/21/25 19:14	7/17/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	12	S.dm	-20,952	65.85	-318		117	D
7/21/25 19:11	7/17/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Belanoff Joseph K	CA	DO	CEO	6	S.dm	-9,939	82.16	-121		3,019	I
7/21/25 19:10	7/17/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	16	S.dm	-23,445	86.97	-270		10	D
7/21/25 19:10	7/17/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	14	S.dm	-9,288	53.08	-175		6	D
7/21/25 16:15	6/23/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		2	S.m	-39	0.9033	-43		5,471	D
7/18/25 18:00	7/16/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	23	S.dm	-11,891	43.87	-271		96	D
7/18/25 16:51	7/17/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Franchi Jean M.	MA	O	CFO	4	S	-511	55.69	-9		70	D
7/18/25 16:30	7/16/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Goldan Keith A.	NY	O	CFO	2	S	-71	13.92	-5		92	D
7/18/25 16:30	7/16/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Metzger Michael A	NY	DO	CEO	3	S.d	-394	13.74	-29		300	D
7/18/25 16:12	7/17/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Reed John C	NJ	O	EVP,Inno	1	S	-3,130	163.55	-19		11	D
7/18/25 16:07	7/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Looker Benjamin	MI	O	GC	2	S	-9	1.15	-8		401	D
7/18/25 16:05	7/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Halladay Benjamin	MI	O	CFO	7	S	-21	1.53	-14		482	D
7/18/25 16:05	7/17/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Silverman Peter B.	P7	O	COO,GC	5	S.dm	-8,691	56.25	-155	-100	0	D
7/18/25 16:05	7/16/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Breedlove Robert Charles	NJ	O	Principa	1	S	-14	8.36	-2		54	D
7/18/25 16:02	7/17/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Francois Cedric	MA	DO	CEO	6	S.dm	-4,067	21.66	-188		1,971	D
7/18/25 16:00	7/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	8	S	-833	26.22	-32		228	D
7/17/25 20:51	7/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Binder Steven B.	CT	D		10	S.d	-2,088	5.16	-404		1,115	D
7/17/25 20:46	7/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Thomson David	CT	O	EVP Genl	7	S.d	-365	4.72	-77		891	D
7/17/25 18:20	7/15/25	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Le-Nguyen Quoc	CA	O	See Rema	4	S	-505	7.80	-65		343	D
7/17/25 17:19	7/15/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kling Douglas F	P7	O	COO	9	S.dm	-4,026	4.94	-815		44	D
7/17/25 16:32	7/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	9	S.dm	-8,866	85.24	-104		62	D
7/17/25 16:31	7/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	11	S.d	-23,111	80.44	-287		249	D
7/17/25 16:15	7/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	8	S.dm	-1,903	15.90	-120		131	D
7/16/25 21:06	7/14/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Tsuchimoto Kim R	IL	D		1	S.d	-356	40.00	-9		11	D
7/16/25 21:03	7/14/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Starr Christopher M	IL	D		1	S.d	-672	40.00	-17		15	D
7/16/25 21:02	7/14/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Robinson Chandler	IL	DO	CEO	1	S.d	-672	40.00	-17		896	D
7/16/25 18:01	7/14/25	TBPH	Theravance Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	Farnum Rhonda	CA	O	SVP,COMM	6	S	-522	10.44	-50		370	D
7/16/25 16:30	7/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	13	S.dm	-6,739	25.57	-263		120	D
7/16/25 16:20	7/14/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yednock Ted	CA	O	EVP,CHIE	9	S.d	-209	5.39	-39		105	D
7/16/25 16:20	7/14/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lew Jennifer	CA	O	EVP,CFO	4	S	-35	3.21	-11		122	D
7/16/25 16:20	7/14/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Overdorf Michael	CA	O	EVP,CHIE	4	S	-31	3.17	-10		131	D
7/16/25 16:14	7/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	5	S	-467	10.99	-43		469	D
7/15/25 17:53	6/16/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	20	S.dm	-44,744	79.19	-565		738	M
7/15/25 17:52	6/5/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Smith Michael Alexander	NJ	O	GC	11	S.dm	-15,324	67.73	-226		97	D
7/15/25 17:02	7/11/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Congleton Jon	PA	DO	CEO	7	S.m	-2,516	12.41	-203		976	D
7/15/25 17:00	7/14/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	9	S.d	-2,018	15.24	-132		141	D
7/15/25 16:36	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	13	S.d	-809	13.89	-58		597	D
7/15/25 16:35	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	13	S.d	-520	14.15	-37		225	D
7/15/25 16:35	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Krepp Sarah	NC	O	Chief Hu	1	S	-38	14.28	-3		142	D
7/15/25 16:34	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	13	S.d	-1,201	13.95	-86		412	D
7/15/25 16:33	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	9	S.d	-2,317	14.43	-161		2,633	D
7/15/25 16:05	7/10/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		2	S.d	-65	40.79	-2		18	D
7/14/25 16:36	7/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		14	S.d	-1,517	52.77	-29	-100	0	D
7/14/25 16:11	7/14/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	16	S	-313	61.89	-5		82	D
7/14/25 16:02	5/8/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	14	S.dm	-3,535	11.32	-312		260	D
7/11/25 18:30	7/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	15	S.dm	-18,389	39.24	-469		716	D
7/11/25 18:17	7/10/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Kozarich John W	FL	D		1	S	-117	125.00	-1		46	D
7/11/25 17:27	7/9/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parmar Kush	CA	DT		2	S.m	-1,069	7.03	-152		4,283	I
7/11/25 17:25	7/9/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5Am Ventures V, L.P.	CA	T		2	S.m	-1,069	7.03	-152		4,283	M
7/11/25 17:14	7/9/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John	V8	DO	CEO	12	S.dm	-82,070	232.89	-352		54,270	D
7/11/25 16:59	7/9/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gheuens Sarah	MA	O	Chief Me	5	S.d	-995	37.36	-27		61	D
7/11/25 16:48	7/9/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quisel John D	MA	DO	CEO	6	S.d	-5,418	59.41	-91		162	D
7/11/25 16:31	7/9/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	7	S.d	-5,779	66.44	-87		117	D
7/11/25 16:30	7/9/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	11	S.d	-4,039	51.42	-79		18	D
7/11/25 16:30	7/9/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	German Christopher Paul	MA	O	Corporat	5	S.d	-518	71.56	-7		3	D
7/11/25 16:30	7/9/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	6	S.dm	-5,828	90.46	-64		66	D
7/10/25 20:56	7/9/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	12	S.d	-1,728	12.45	-139		370	D
7/10/25 20:56	7/8/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nougues Maximo F	CA	O	CFO	4	S.m	-99	3.38	-29		204	D
7/10/25 20:52	7/8/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hunt Douglas M	CA	O	See Rema	4	S.m	-83	3.38	-24		165	D
7/10/25 20:50	7/9/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yea Christopher	MA	O	Chief De	11	S.d	-931	13.04	-71		128	D
7/10/25 20:49	7/8/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Auerbach Alan H	CA	DOT	P,CEO	4	S.m	-416	3.42	-122		7,181	D
7/10/25 16:30	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Silverstein Christine Berni	OH	D		2	S	-193	4.96	-39		120	D
7/10/25 16:30	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seshadri Vishwas	OH	DO	CEO	3	S	-869	5.99	-145		1,355	D
7/10/25 16:30	7/8/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wuchterl Donald A.	OH	D		1	S	-30	5.82	-5		145	D
7/10/25 16:30	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Charles Faith L.	OH	D		1	S	-63	5.86	-11		139	D
7/10/25 16:30	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	O'Malley Brendan M.	OH	O	SVP,GC	2	S	-173	6.20	-28		378	D
7/10/25 16:30	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Alvino Mark	OH	D		6	S	-294	5.15	-57		92	D
7/10/25 16:17	7/8/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	Plassche Douglas	NJ	O	EVP Oper	2	S.m	-678	0.5084	-1,334		2,300	D
7/9/25 19:29	7/7/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	15	S.dm	-3,456	23.22	-149		397	I
7/9/25 19:00	7/7/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	15	S.dm	-7,613	49.75	-153		198	D
7/9/25 17:00	7/7/25	MURA	Mural Oncology Plc	L2	Health	Drug	Pharmaceutical Preparations	Loew Caroline	L2	DO	CEO	4	S.d	-91	2.83	-32		306	D
7/8/25 17:55	7/7/25	BRFG	Bullfrog Ai Holdings, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Singh Vininder	MD	DOT	CEO	11	S.m	-620	2.07	-300		2,542	D
7/8/25 16:37	2/19/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	Pinto Shelly	CA	O	Interim	8	S	-28	2.43	-12		94	D
7/8/25 16:20	7/3/25	BPMC	Blueprint Medicines Corp	DE	Health	Drug	Pharmaceutical Preparations	Rossi Christina	MA	O	COO	9	S	-2,304	97.70	-24		72	D
7/8/25 16:20	7/3/25	BPMC	Blueprint Medicines Corp	DE	Health	Drug	Pharmaceutical Preparations	Carter Percy H.	MA	O	Chief Sc	5	S	-1,468	107.35	-14		57	D
7/8/25 16:05	7/3/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ondrey Aaron	NJ	O	CFO	2	S	-44	4.90	-9		130	D
7/8/25 16:00	7/3/25	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schambye Hans T.	G7	DO	CEO	2	S.d	-10	4.81	-2		4	D
7/8/25 16:00	7/3/25	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Winslow Garrett	G7	O	GC	2	S.d	-4	4.81	-1		1	D
7/8/25 16:00	7/3/25	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Firmani Lori	G7	O	Interim	2	S.d	-2	4.82	0		1	D
7/7/25 17:20	7/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Lee Kevin	X0	DO	CEO	6	S.dm	-466	14.19	-33		492	D
7/7/25 17:20	7/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Skynner Michael	X0	O	CTO	6	S.dm	-151	14.02	-11		124	D
7/7/25 17:20	7/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Milnes Alistair	X0	O	COO	6	S.dm	-174	13.70	-13		100	D
7/7/25 17:20	7/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Hannay Michael Charles Ferguson	X0	O	CHIEF PR	6	S.dm	-57	13.20	-4		55	D
7/7/25 17:20	7/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Thompson Travis Alvin	X0	O	Chief Ac	7	S.dm	-239	20.04	-12		32	D
7/7/25 17:20	7/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Young Alethia	X0	O	CFO	3	S.d	-23	12.58	-2		46	D
7/7/25 16:03	7/3/25	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Moukheibir Catherine	MA	D		2	S.dm	-1,664	16.08	-104		49	D
7/3/25 19:51	7/1/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticktin Robert	NJ	O	GC,COO	1	S	-25	1.06	-23		99	D
7/3/25 19:50	7/1/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jalota Deepika	NJ	O	Chief De	2	S	-46	1.14	-40		118	D
7/3/25 19:49	7/1/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Carulli Michael	NJ	O	CFO	2	S	-34	1.11	-31		88	D
7/3/25 19:48	7/1/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mack David Henry	NJ	DO	P,CEO	1	S	-62	1.06	-58		906	D
7/3/25 19:39	7/1/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	Aure Carl	UT	O	CFO	1	S.d	-37	13.39	-3		133	D
7/3/25 18:48	7/2/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Howe Jolanda	CA	O	SVP,GLOB	8	S.dm	-2,970	44.56	-67		5	D
7/3/25 18:00	7/1/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lamy Patrick	CA	O	SVP,Comm	12	S.d	-1,456	48.08	-30		34	D
7/3/25 17:30	7/2/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Petersen Floyd F.	CA	D		10	S.d	-406	38.69	-11		81	D
7/3/25 17:12	7/2/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Garfield Alastair	MA	O	Chief Sc	1	S.d	-85	64.81	-1		3	D
7/3/25 16:30	7/1/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	9	S.dm	-38,847	35.56	-1,092		6,906	I
7/3/25 16:21	7/1/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Karas Eric	CA	O	Chief Co	6	S.dm	-1,055	15.08	-70		10	D
7/3/25 16:15	7/2/25	KZR	Kezar Life Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chiang Pichi Luo	CA	O	SVP,Corp	1	S	-1	4.28	0		3	D
7/3/25 16:15	7/2/25	KZR	Kezar Life Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schiller Mark C.	CA	O	COO	2	S	-6	0.8663	-7		33	D
7/3/25 16:07	7/2/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Du Ying	MA	DO	Chairper	12	S.dm	-14,654	30.79	-476		1,143	D
7/3/25 15:31	7/3/25	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lian Brian	CA	DO	P,CEO	6	S.d	-38,537	57.76	-667		2,388	D
7/3/25 15:31	5/3/24	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zante Greg	CA	O	CFO	5	S.d	-18,266	67.87	-269		187	D
7/3/25 15:30	5/1/24	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mancini Marianna	CA	O	COO	4	S.d	-25,602	71.53	-358		378	D
7/3/25 14:56	2/3/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	Cozadd Bruce C	L2	DO	CB,CEO	9	S.m	-2,238	127.88	-18		464	D
7/3/25 14:55	7/1/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kuriakose Emil	CA	O	Chief Me	3	S	-32	5.03	-6		54	D
7/3/25 13:34	7/2/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Renton Hollings	CA	D		5	S.d	-1,167	25.43	-46		5	D
7/3/25 13:28	7/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chole Timothy	MI	O	SVP,CCO	5	S	-14	1.28	-11		128	D
7/3/25 13:26	7/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Strobeck Mark	MI	DO	P,CEO	5	S	-31	1.25	-25		338	D
7/3/25 13:24	7/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Neri Jesse	MI	O	SVP,CFO	3	S	-2	0.9138	-3		127	D
7/2/25 17:28	7/1/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Inrig Jula	CA	O	Chief Me	6	S.dm	-260	18.54	-14		90	D
7/2/25 16:25	7/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		14	S.d	-1,648	11.83	-139		205	D
7/2/25 16:15	6/30/25	PMN	Promis Neurosciences Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Gordon Michael S	MA	T		1	S	0	0.00	-93		2,124	D
7/2/25 16:09	7/1/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticho Barry	MA	O	Chief Me	16	S.dm	-1,891	12.07	-157		61	D
7/2/25 16:07	7/1/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	6	S.dm	-691	10.03	-69		107	D
7/1/25 21:23	6/27/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		9	S.dm	-72,027	18.76	-3,839		24,270	I
7/1/25 21:17	6/27/25	CRVS	Corvus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Thompson Peter A.	CA	DT		3	S.dm	-17,478	8.21	-2,129		15,537	I
7/1/25 19:48	6/27/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Viking Global Investors LP	CT	T		2	S	-260,990	39.75	-6,566		22,055	I
7/1/25 17:01	6/30/25	AKBA	Akebia Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ostrowski Erik	MA	O	SVP,CFO,	1	S	-152	3.67	-41		504	D
7/1/25 16:49	6/27/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Abi-Saab Walid	P7	O	Chief Me	3	S.d	-41	9.53	-4		152	D
7/1/25 16:42	6/27/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flynn James E	NY	DTH	* Direct	3	S.m	-219,307	66.39	-3,303		28,506	I
7/1/25 16:37	6/30/25	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brennan Aoife	MA	DO	P,CEO	1	S.d	-25	1.22	-21		48	D
6/30/25 17:51	6/26/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Valantine Hannah	CA	D		3	S.d	-799	36.50	-22		8	M
6/30/25 17:02	6/26/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Thompson Rahsaan	FL	OH	Chief Le	1	S	-221	9.21	-24		43	D
6/27/25 16:27	6/27/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	Shanghai Fosun Pharmaceutical (Group) Co., Ltd.	F4	T		3	S.m	-32,889	11.47	-2,868		2,921	I
6/27/25 16:15	6/26/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Edmondson Frazor Titus III	MA	O	GC	10	S.d	-1,468	26.32	-56		39	D
6/27/25 16:15	6/25/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Lee Ting-Chuan	CA	D		1	S	-1	0.5100	-3	0	1,429	D
6/27/25 16:15	6/25/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Tsai Chun-Jung	CA	D		2	S.m	-22	0.5166	-43		1,402	D
6/27/25 16:15	6/26/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	10	S.d	-685	29.91	-23		27	D
6/26/25 20:00	6/24/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Shelton Jerrell	TN	DO	P,CEO	9	S.dm	-4,936	7.55	-654		937	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kharabi Darius	MA	O	CHIEF BU	5	S.d	-62	4.91	-13		68	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Reumuth Mary	MA	O	CFO	5	S.d	-69	4.87	-14		69	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bazemore Todd	MA	O	SEE REMA	5	S.d	-79	4.88	-16		88	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brazzell Romulus K	MA	O	SEE REMA	5	S.d	-92	4.86	-19		92	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Iwicki Mark T	MA	D		6	S.d	-295	4.67	-63		280	D
6/26/25 17:26	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burns James William	MA	O	GC	3	S.d	-1,372	48.05	-29		29	D
6/26/25 17:24	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jones Cecilia	MA	O	CFO	3	S.d	-265	40.20	-7		30	D
6/26/25 17:23	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Milanova Tsveta	MA	O	Chief Co	3	S.d	-243	33.48	-7		26	D
6/26/25 17:22	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goff Brian	MA	DO	CEO	4	S.d	-2,153	39.25	-55		112	D
6/26/25 17:08	6/24/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCormick Frank	CA	D		1	S	-4,423	44.23	-100		963	I
6/25/25 18:52	6/23/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saccomano Nicholas A	CO	DO	P,CEO	2	S.m	-3	2.89	-1		4	D
6/25/25 18:49	6/23/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leverone Jason A.	CO	O	CFO	2	S.m	-10	2.89	-3		13	D
6/25/25 17:08	6/23/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wu Xiaobin	V8	O	P,COO	13	S.dm	-44,882	254.28	-177		1,262	D
6/25/25 17:08	6/24/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Xiaodong	V8	DH	Chair, S	10	S.d	-77,751	221.62	-351		10,325	D
6/25/25 16:38	6/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mesa Nilda	MD	D		5	S	-532	310.29	-2		6	D
6/25/25 16:36	6/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Giltner Richard	MD	D		2	S.d	-4,696	360.25	-13		19	D
6/24/25 20:29	6/23/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Reardon Andrew	FL	O	CLO,Secr	6	S.d	-1,408	90.81	-16		33	D
6/24/25 18:08	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Springhorn Jeremy P.	P7	D		2	S	-42	9.66	-4		38	D
6/24/25 18:03	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Post Leonard E	P7	D		2	S	-42	9.68	-4		30	D
6/24/25 17:53	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Kaye Jack	P7	D		2	S	-42	9.69	-4		20	D
6/24/25 17:50	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Jacques Rachelle Suzanne	P7	D		2	S	-42	9.68	-4		28	D
6/24/25 17:45	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Gut Robert	P7	D		2	S	-66	9.67	-7		57	D
6/24/25 17:42	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Balachandran Madhavan	P7	D		2	S	-42	9.66	-4		38	D
6/24/25 17:34	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Meek David D.	P7	D		2	S	-42	9.66	-4		34	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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