Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
8/5/25 20:32	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Cunningham Kenneth	X0	D		2	M.d	142	4.08	35	77	80	D
8/5/25 20:32	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Cunningham Kenneth	X0	D		2	S.d	-142	4.08	-35		80	D
8/5/25 20:31	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Deschamps Lisa	X0	D		2	M.d	124	3.72	33	65	85	D
8/5/25 20:31	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Deschamps Lisa	X0	D		2	S.d	-124	3.72	-33		85	D
8/5/25 20:30	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Fisher Andrew	X0	O	GC	8	M.d	2,224	4.31	517		440	D
8/5/25 20:30	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Fisher Andrew	X0	O	GC	8	S.d	-2,224	4.31	-517		440	D
8/5/25 20:28	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Hahn Mark W	X0	O	CFO	5	M.dm	11,040	7.39	1,494	13	12,679	D
8/5/25 20:28	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Hahn Mark W	X0	O	CFO	5	S.dm	-11,040	7.39	-1,494		12,679	D
8/5/25 20:27	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Rickard Kathleen A.	X0	O	Chief Me	4	M.d	1,781	5.39	330	15	2,607	D
8/5/25 20:27	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Rickard Kathleen A.	X0	O	Chief Me	4	S.d	-1,781	5.39	-330		2,607	D
8/5/25 20:26	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Ackermann Christina	X0	D		4	M.d	439	4.15	106		64	D
8/5/25 20:26	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Ackermann Christina	X0	D		4	S.d	-439	4.15	-106		64	D
8/5/25 20:25	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Austwick Michael	X0	D		2	M.d	148	4.20	35		13	D
8/5/25 20:25	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Austwick Michael	X0	D		2	S.d	-148	4.20	-35		13	D
8/5/25 20:24	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Brady James Aloysius	X0	D		2	M.d	11	0.4363	25		23	D
8/5/25 20:24	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Brady James Aloysius	X0	D		2	S.d	-11	0.4363	-25		23	D
8/5/25 20:22	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Zaccardelli David	X0	DO	P,CEO	5	M.dm	11,041	7.39	1,494	12	13,590	D
8/5/25 20:22	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Zaccardelli David	X0	DO	P,CEO	5	S.dm	-11,041	7.39	-1,494		13,590	D
8/5/25 20:21	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Ebsworth David R	X0	D		2	M.d	25	0.9661	26	2	1,498	D
8/5/25 20:21	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Ebsworth David R	X0	D		2	S.d	-25	0.9661	-26		1,498	D
8/5/25 20:20	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Edwards Martin	X0	D		2	M.d	142	4.08	35	28	158	D
8/5/25 20:20	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Edwards Martin	X0	D		2	S.d	-142	4.08	-35		158	D
8/5/25 20:18	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Shah Mahendra	X0	D		2	M.d	47	1.72	28	42	93	D
8/5/25 20:18	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Shah Mahendra	X0	D		2	S.d	-47	1.72	-28		93	D
8/5/25 20:17	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Sinha Vikas	X0	D		6	M.ad	3,292	4.93	668		94	D
8/5/25 20:17	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Sinha Vikas	X0	D		6	S.ad	-3,292	4.93	-668		94	D
8/5/25 20:16	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Ullman Anders	X0	D		1	M.d	0	0.00	24	7	359	D
8/5/25 18:51	8/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	8	M.dm	4,563	41.48	110	999%	117	M
8/5/25 18:51	8/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	8	S.dm	-4,563	41.48	-110		117	M
8/5/25 18:51	8/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Belanoff Joseph K	CA	DO	CEO	3	S	-6,101	75.68	-81		2,902	I
8/5/25 18:47	8/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	8	M.dm	1,294	43.12	30		10	D
8/5/25 18:47	8/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	8	S.dm	-1,294	43.12	-30		10	D
8/5/25 18:29	8/4/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watanabe Todd	CA	DO	See Rema	1	S	-165	14.33	-12		1,135	D
8/5/25 18:28	5/8/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	4	S.dm	-523	8.17	-64		115	D
8/5/25 18:28	8/4/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vairavan Latha	CA	O	SVP CFO	1	S	-1	14.33	0	0	65	D
8/5/25 18:28	8/5/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	12	M.d	536	22.33	24	21	141	D
8/5/25 18:28	8/5/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	12	S.d	-536	22.33	-24		141	D
8/5/25 18:28	5/28/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Matsuda Masaru	CA	O	See Rema	2	S	-115	14.21	-8		203	D
8/5/25 18:28	8/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		4	M.d	406	10.32	39	56	109	D
8/5/25 18:28	8/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		4	S.d	-406	10.32	-39		109	D
8/5/25 18:01	8/1/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	Gallman Cari	NJ	O	EVP,GC	1	M.d	0	0.00	1	14	9	D
8/5/25 17:58	8/2/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	Short Bartie Wendy	NJ	O	EVP,Corp	3	M.d	17	1.83	9		5	D
8/5/25 17:58	8/2/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	Short Bartie Wendy	NJ	O	EVP,Corp	3	S.d	-17	1.83	-9		5	D
8/5/25 17:31	8/1/25	AUPH	Aurinia Pharmaceuticals Inc.		Health	Drug	Pharmaceutical Preparations	Tang Kevin	CA	D		1	P.m	13,590	10.45	1,300	13	11,330	I
8/5/25 17:28	8/4/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Schneider Eugene	CA	O	EVP,Chf	1	S	-409	42.80	-10		52	D
8/5/25 17:27	8/4/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moriarty John B	CA	O	GC	1	S	-81	36.21	-2		48	D
8/5/25 17:16	8/1/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Rosenberg Aaron	V8	O	CFO	1	S	-346	290.47	-1		215	D
8/5/25 17:03	8/1/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Kozarich John W	FL	D		3	S.d	-304	79.90	-4		46	D
8/5/25 16:54	8/1/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	Cozadd Bruce C	L2	DO	CB,CEO	3	S.m	-330	109.93	-3		438	D
8/5/25 16:07	8/1/25	AUPH	Aurinia Pharmaceuticals Inc.		Health	Drug	Pharmaceutical Preparations	Keenan Greg	A0	O	Chief Me	1	S	-210	10.50	-20		133	D
8/5/25 16:05	8/1/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticho Barry	MA	O	Chief Me	3	S.m	-192	11.17	-17		26	D
8/5/25 16:04	8/1/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Jover Placid	L3	O	See "Rem	2	M.d	92	4.86	19		7	D
8/5/25 16:04	8/1/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Jover Placid	L3	O	See "Rem	2	S.d	-92	4.86	-19		7	D
8/5/25 16:02	8/1/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Hughes Eric A	L3	O	See "Rem	2	M.d	799	7.58	105		0	D
8/5/25 16:02	8/1/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Hughes Eric A	L3	O	See "Rem	2	S.d	-799	7.58	-105	-100	0	D
8/5/25 08:46	8/4/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Williams David Michael	NJ	O	EVP,Chie	1	M.d	1,357	79.29	17	108	33	D
8/5/25 08:43	8/4/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Guindo Chirfi	NJ	O	CMO	1	M.d	2,926	79.29	37	70	89	D
8/4/25 19:23	7/30/25	CYCC	Cyclacel Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lazar David E.	R1	T		1	S	-83	12.36	-7		156	D
8/4/25 19:17	8/1/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Petersen Floyd F.	CA	D		3	S.d	-35	23.32	-2		78	D
8/4/25 18:28	7/31/25	LRMR	Larimar Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flynn James E	NY	DTH	* Direct	2	P	43,663	4.32	10,115	33	40,381	I
8/4/25 18:00	7/31/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Shelton Jerrell	TN	DO	P,CEO	11	M.dm	5,810	5.60	1,037	999%	1,037	D
8/4/25 17:29	7/31/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Forbes William P	NC	O	EVP,Chie	3	M.d	0	0.00	28	23	151	D
8/4/25 17:27	7/31/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Duarte IRA	NC	O	EVP,CFO	3	M.d	0	0.00	28	21	164	D
8/4/25 17:21	7/31/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Collard Craig A	NC	DO	CEO	2	M.d	0	0.00	49	11	475	D
8/4/25 17:00	8/1/25	AMRN	Amarin Corp Plcuk	X0	Health	Drug	Pharmaceutical Preparations	Fishman Peter L.	NJ	O	SVP,CFO	1	M.d	0	0.00	0	8	4	D
8/4/25 16:43	8/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Gaffin David Joseph	MA	O	EVP,CLO,	1	M.d	0	0.00	2	1	205	D
8/4/25 16:16	8/1/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Seymour Melissa	IN	O	EVP,Glob	1	M.d	0	0.00	1		1	D
8/4/25 09:00	7/31/25	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	Titterton Lewis H Jr	CA	D		2	P	62	3.11	20	2	953	D
8/1/25 17:09	8/1/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Van Houte Hans	CA	O	CFO	3	S.d	-111	5.25	-21		41	D
8/1/25 16:36	7/30/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Popovits Kimberly J	X0	D		2	M.d	2,693	20.37	132		13	D
8/1/25 16:32	7/30/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		3	S.m	-3,175	61.03	-52		1,148	I
8/1/25 16:30	7/30/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Carson William H.	CA	D		2	P	20	2.45	8	32	34	D
8/1/25 16:30	7/30/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	DT		4	S.dm	-634	2.59	-245		96	I
8/1/25 16:30	7/30/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	6	M.d	1,227	51.13	24	100	48	D
8/1/25 16:30	7/30/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	6	S.d	-1,227	51.13	-24		48	D
8/1/25 16:06	7/30/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	3	M.d	237	39.37	6	3	180	D
8/1/25 16:06	7/30/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	3	S.d	-237	39.37	-6		180	D
7/31/25 17:05	7/29/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Lai	V8	O	Global H	5	S.m	-2,564	282.50	-9		1,769	I
7/31/25 17:04	7/30/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	3	S	-572	280.11	-2		278	D
7/31/25 16:38	7/29/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	6	S	-1,021	34.02	-30		417	D
7/31/25 16:15	7/31/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mack David J.	CT	D		3	M.d	0	0.00	5	50	15	D
7/31/25 09:00	7/30/25	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	Kumar Amit	CA	O	CEO	3	P	60	3.00	20	4	580	D
7/30/25 20:12	7/28/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levy Adam Scott	PA	O	CFO,Secr	2	S.m	-1,233	14.60	-84		207	D
7/30/25 18:49	7/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ring Christine	CA	O	GC	2	M.d	46	3.21	14	48	44	D
7/30/25 18:49	7/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ring Christine	CA	O	GC	2	S.d	-46	3.21	-14		44	D
7/30/25 18:48	7/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hansen Gwenn	CA	O	Chief Sc	2	M.d	52	3.21	16	30	69	D
7/30/25 18:48	7/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hansen Gwenn	CA	O	Chief Sc	2	S.d	-52	3.21	-16		69	D
7/30/25 17:57	7/28/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	10	M.d	311	11.33	28		23	D
7/30/25 17:57	7/28/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	10	S.d	-311	11.33	-28		23	D
7/30/25 17:12	7/29/25	LEXX	Lexaria Bioscience Corp.	NV	Health	Drug	Pharmaceutical Preparations	Bunka Christopher	A1	D		1	P.dm	25	0.9179	28	3	910	I
7/30/25 17:00	7/29/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	3	S.d	-395	10.29	-38		216	D
7/30/25 16:56	7/29/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Poulton Stuart	MA	O	EVP,Chie	1	S	-1	4.37	0		27	D
7/30/25 16:31	7/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	7	S.d	-114	4.86	-23		194	D
7/30/25 16:30	7/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Boyle Dana	NC	O	Chief Ac	2	S	-38	16.76	-2		187	D
7/30/25 16:03	7/28/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Smith Jason Drew	NJ	O	GC	2	M	144	5.99	24	138	41	D
7/30/25 16:03	7/28/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Smith Jason Drew	NJ	O	GC	2	S	-144	5.99	-24		41	D
7/30/25 16:02	7/28/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Schoenberg Mark	NJ	O	Chief Me	4	M.d	137	4.51	30	24	158	D
7/30/25 16:02	7/28/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Schoenberg Mark	NJ	O	Chief Me	4	S.d	-137	4.51	-30		158	D
7/30/25 13:47	7/29/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	12	M.d	209	2.85	73		0	D
7/30/25 13:47	7/29/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	12	S.d	-209	2.85	-73	-100	0	D
7/30/25 12:37	7/29/25	LEXX	Lexaria Bioscience Corp.	NV	Health	Drug	Pharmaceutical Preparations	McKechnie William Edward	A6	D		1	P.d	5	0.9064	5	19	31	D
7/30/25 11:34	7/29/25	LEXX	Lexaria Bioscience Corp.	NV	Health	Drug	Pharmaceutical Preparations	Docherty John Martin	A6	DO	P,CSO	1	P.d	5	0.9280	5	10	59	D
7/30/25 11:23	7/29/25	LEXX	Lexaria Bioscience Corp.	NV	Health	Drug	Pharmaceutical Preparations	Carle Vanessa	A1	O	Secretar	1	P.d	1	0.9107	1		1	D
7/30/25 11:14	7/29/25	LEXX	Lexaria Bioscience Corp.	NV	Health	Drug	Pharmaceutical Preparations	Christopher Richard	A1	DO	CEO	1	P.d	14	0.9094	15	15	115	D
7/29/25 18:56	7/26/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	6	M.d	2,067	41.47	50		21	D
7/29/25 18:56	7/29/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	6	S.d	-2,067	41.47	-50		21	D
7/29/25 16:52	7/25/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stauderman Kenneth A.	CA	O	Chief Sc	3	S	-9	3.15	-3		13	M
7/29/25 16:52	7/28/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stauderman Kenneth A.	CA	O	Chief Sc	3	P	9	3.15	3	30	13	M
7/28/25 18:08	7/25/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Patel Dinesh V Ph D	CA	DO	P,CEO	2	S.m	-3,451	54.89	-63		531	D
7/28/25 17:14	7/25/25	ZTS	Zoetis Inc.		Health	Drug	Pharmaceutical Preparations	Broadhurst Vanessa	NJ	D		1	M.d	0	0.00	1	100	3	D
7/28/25 06:27	7/25/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Patusky Christopher	MD	D		1	M.d	0	0.00	1	30	3	D
7/28/25 06:26	7/25/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Olian Judy D.	MD	D		1	M.d	0	0.00	1	21	7	D
7/28/25 06:26	7/25/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mesa Nilda	MD	D		2	M.d	187	151.45	1	29	5	D
7/28/25 06:24	7/25/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Kurzweil Ray	MD	D		1	M.d	0	0.00	1	5	13	D
7/28/25 06:24	7/25/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Giltner Richard	MD	D		3	M.d	1,756	190.37	9	81	21	D
7/28/25 06:21	7/25/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Sullivan Louis W	MD	D		1	M.d	0	0.00	1	18	4	I
7/28/25 06:13	7/25/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Causey Christopher	MD	D		1	M.d	0	0.00	1	32	5	D
7/28/25 06:10	6/26/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Malcolm Jan	MD	D		1	M.dm	0	0.00	1		1	D
7/25/25 19:06	7/23/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tahir Misbah	CA	O	CFO	2	S	-13	1.26	-10		179	D
7/25/25 19:03	7/23/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harler Mary Beth	CA	DO	CEO	2	S	-20	1.27	-16		338	D
7/25/25 19:01	7/23/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Decker Lisa Lynn	CA	O	CHIEF BU	2	S	-7	1.26	-5		73	D
7/25/25 18:56	7/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	12	M.d	28,267	214.14	132		37	D
7/25/25 18:56	7/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	12	S.d	-28,267	214.14	-132		37	D
7/25/25 18:54	7/23/25	DMAC	Diamedica Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Stahlberg Jan	V7	T		1	P	5,400	3.50	1,543	30	6,764	I
7/25/25 18:24	7/25/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Weinhoff Gregory M	X0	O	Chief Bu	6	M.d	538	8.97	60	96	122	D
7/25/25 18:24	7/25/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Weinhoff Gregory M	X0	O	Chief Bu	6	S.d	-538	8.97	-60		122	D
7/25/25 18:05	7/10/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	Kirkov Kirko	NJ	O	Chief Co	1	P	10	0.5890	16		16	D
7/25/25 17:49	7/23/25	DMAC	Diamedica Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Von Koch Thomas	V7	T		1	P	10,000	3.50	2,857	52	8,384	I
7/25/25 16:35	7/23/25	DMAC	Diamedica Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Jacinto Richard II	FL	T		1	P	1,400	3.50	400	9	4,959	I
7/25/25 16:00	7/24/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		1	S	-225,419	805.07	-280	0	95,737	D
7/24/25 17:00	7/22/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Mandalam Ramkumar	TN	D		6	M.dm	749	4.98	150		92	D
7/24/25 17:00	7/22/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Mandalam Ramkumar	TN	D		6	S.dm	-749	4.98	-150		92	D
7/23/25 21:10	7/21/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baum Mark L	TN	DOT	CEO	1	M.d	4,722	7.87	600	26	2,886	D
7/23/25 21:00	7/21/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	8	M.dm	21,034	7.05	2,985		1,462	D
7/23/25 21:00	7/21/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	8	S.dm	-21,034	7.05	-2,985		1,462	D
7/23/25 18:52	7/21/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	4	S	-778	20.74	-38		985	I
7/23/25 18:09	7/22/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peters Malte	NY	DO	CEO	1	S	-27	0.9200	-29		80	D
7/23/25 18:07	7/22/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Coelho Mary Theresa	NY	DO	EVP,CFO	1	S	-13	0.9200	-14		56	D
7/23/25 17:18	7/22/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Abate Kristin	MA	O	Chief Ac	1	S	-1	4.00	0		9	D
7/23/25 17:00	7/22/25	MURA	Mural Oncology Plc	L2	Health	Drug	Pharmaceutical Preparations	Keson-Brookes Maiken	L2	O	See Rema	2	S	-12	2.48	-5		71	D
7/23/25 16:35	7/21/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	10	M.dm	27,846	63.97	435		113	D
7/23/25 16:35	7/21/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	10	S.dm	-27,846	63.97	-435		113	D
7/23/25 16:30	7/21/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	5	S.d	-242	6.60	-37		273	D
7/23/25 16:16	7/21/25	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Happel David	CA	DO	P,CEO	1	S	-598	9.13	-65		690	D
7/23/25 16:15	7/21/25	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Martins Eduardo Bruno	CA	O	Chief Me	1	S	-76	9.13	-8		107	D
7/23/25 16:14	7/21/25	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rozek Elizabeth	CA	O	GC,CCO	1	S	-98	9.13	-11		184	D
7/23/25 11:55	7/22/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Roberts Eric W	CA	DOT	CHIEF BU	8	P.m	74	2.04	36	4	1,014	I
7/22/25 20:26	7/22/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Steinhart Richard I	CT	O	CFO	2	M.dm	0	0.00	1	12	6	D
7/22/25 20:25	7/22/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodriguez Javier	CT	O	See Rema	2	M.dm	0	0.00	1	12	7	D
7/22/25 19:51	7/18/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cesano Alessandra	CA	D		2	S	-132	3.38	-39		69	D
7/22/25 17:08	7/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taub Rebecca	PA	D		4	M.dm	10,913	181.27	60	6	1,117	D
7/22/25 17:08	7/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taub Rebecca	PA	D		4	S.dm	-10,913	181.27	-60		1,117	D
7/22/25 17:06	7/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedman Paul A	PA	D		4	M.dm	10,975	181.25	61	8	843	D
7/22/25 17:06	7/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedman Paul A	PA	D		4	S.dm	-10,975	181.25	-61		843	D
7/22/25 16:15	7/22/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vazzano Joseph Walter	OH	O	CFO	3	S	-279	6.24	-45		491	D
7/22/25 15:24	7/22/25	ETST	Earth Science Tech, Inc.	FL	Health	Drug	Pharmaceutical Preparations	Saumat Giorgio R.	FL	DOT	CEO	2	P	30	0.2017	150	0	122,930	D
7/22/25 07:36	7/21/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Eldred Kary	GA	D		1	P	3	2.93	1	1	69	D
7/21/25 19:39	7/21/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Saha Saurabh	X0	DO	CEO	6	M.d	2,905	8.80	330		259	D
7/21/25 19:39	7/21/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Saha Saurabh	X0	DO	CEO	6	S.d	-2,905	8.80	-330		259	D
7/21/25 19:21	7/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	4	S	-792	21.11	-38		973	I
7/21/25 19:10	7/17/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	10	M.dm	6,124	47.62	129		5	D
7/21/25 19:10	7/17/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	10	S.dm	-6,124	47.62	-129		5	D
7/21/25 16:43	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harsanyi Zsolt	WA	D		1	M.d	0	0.00	0		0	D
7/21/25 16:42	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kunz Barbara Lopez	WA	D		1	M.d	0	0.00	0		0	D
7/21/25 16:41	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Abdun-Nabi Daniel	WA	D		1	M.d	0	0.00	0		0	D
7/21/25 16:40	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Grant Grady III	WA	D		1	M.d	0	0.00	0		0	D
7/21/25 16:39	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Niederhuber John	WA	D		1	M.d	0	0.00	0		0	D
7/21/25 16:38	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taylor Daphne	WA	O	SVP,CFO	1	M.d	0	0.00	0		0	D
7/21/25 16:37	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kwon Soyoung	WA	O	SVP,GC,B	1	M.d	0	0.00	0	300	0	D
7/21/25 16:36	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	White Marvin L	WA	DO	P,CEO	1	M.d	0	0.00	0	500	0	D
7/21/25 16:35	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lamothe Jeffrey G.	WA	O	EVP,COO	1	M.d	0	0.00	0	500	0	D
7/21/25 16:15	6/23/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		2	S.m	-39	0.9033	-43		5,471	D
7/21/25 14:02	7/21/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leheny A. Rachel	CA	DOT	CEO	2	P	10	2.74	4	0	875	I
7/21/25 08:30	7/18/25	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	Baskies Arnold M	CA	D		1	P	17	3.39	5	4	125	D
7/18/25 18:00	7/16/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	8	M.d	2,326	36.10	64	211	95	D
7/18/25 18:00	7/16/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	8	S.d	-2,326	36.10	-64		95	D
7/18/25 16:51	7/17/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Franchi Jean M.	MA	O	CFO	3	S	-339	56.27	-6		68	D
7/18/25 16:30	7/16/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Goldan Keith A.	NY	O	CFO	2	S	-12	2.80	-4		94	D
7/18/25 16:30	7/16/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Metzger Michael A	NY	DO	CEO	1	S	-70	9.29	-8		299	D
7/18/25 16:12	7/17/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Reed John C	NJ	O	EVP,Inno	1	S	-3,130	163.55	-19		11	D
7/18/25 16:07	7/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Looker Benjamin	MI	O	GC	2	S	-9	1.15	-8		401	D
7/18/25 16:05	7/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Halladay Benjamin	MI	O	CFO	2	S	-8	1.15	-7		474	D
7/18/25 16:05	7/17/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Silverman Peter B.	P7	O	COO,GC	6	M.dm	6,267	37.98	165		0	D
7/18/25 16:05	7/17/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Silverman Peter B.	P7	O	COO,GC	6	S.dm	-6,267	37.98	-165	-100	0	D
7/18/25 16:05	7/16/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Breedlove Robert Charles	NJ	O	Principa	1	S	-14	8.36	-2		54	D
7/18/25 16:02	7/17/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Francois Cedric	MA	DO	CEO	4	M.dm	3,535	15.10	234	14	1,882	D
7/18/25 16:02	7/17/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Francois Cedric	MA	DO	CEO	4	S.dm	-3,535	15.10	-234		1,882	D
7/18/25 16:00	7/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	2	S	-192	19.16	-10		214	D
7/18/25 14:42	7/18/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Robert N	CA	D		1	P	13	2.87	5	1	422	D
7/18/25 10:38	7/17/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Freeman Kevin D	GA	D		1	P	14	2.90	5	4	148	D
7/17/25 20:51	7/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Binder Steven B.	CT	D		4	S.d	-982	4.24	-232		1,007	D
7/17/25 20:46	7/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Thomson David	CT	O	EVP Genl	3	S.d	-190	4.53	-42		891	D
7/17/25 18:20	7/15/25	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Le-Nguyen Quoc	CA	O	See Rema	1	S	-115	11.02	-10		324	D
7/17/25 17:19	7/15/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kling Douglas F	P7	O	COO	6	M.dm	7,120	11.92	597		44	D
7/17/25 17:19	7/15/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kling Douglas F	P7	O	COO	6	S.dm	-7,120	11.92	-597		44	D
7/17/25 16:59	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Loscalzo Joseph	CA	D		1	M.d	0	0.00	4	13	36	D
7/17/25 16:54	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Yang Michael J.	CA	D		1	M.d	0	0.00	4	211	6	D
7/17/25 16:54	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Wender Joseph H	CA	D		1	M.d	0	0.00	4	3	137	I
7/17/25 16:54	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Parshall B Lynne	CA	D		1	M.d	0	0.00	4	5	91	D
7/17/25 16:54	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Herman Joan E	CA	D		1	M.d	0	0.00	4	10	46	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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