Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
5/2/25 20:41	4/30/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	3	7	M.d	0	0.00	142	26	685	D
5/2/25 20:27	5/1/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	3	6	S.d	-7,641	14.82	-515		10,831	D
5/2/25 20:00	5/1/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	17	M.d	313	6.78	46	80	104	D
5/2/25 20:00	5/2/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	17	S.d	-313	6.78	-46		104	D
5/2/25 20:00	5/1/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	9	M.dm	25,854	30.39	851	8	11,272	D
5/2/25 20:00	5/1/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	9	S.dm	-25,854	30.39	-851		11,272	D
5/2/25 19:55	5/1/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	15	M.d	4,102	26.36	156	28	715	D
5/2/25 19:55	5/1/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	15	S.d	-4,102	26.36	-156		715	D
5/2/25 18:18	5/2/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	10	S.d	-380	6.61	-58		139	D
5/2/25 17:04	4/30/25	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	8	10	S.dm	-68,907	90.66	-760		825	D
5/2/25 16:55	3/26/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	6	20	P.dm	4,284	3.58	1,196	19	7,549	I
5/2/25 16:43	5/1/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	25	M.dm	40,323	67.02	602	62	1,571	I
5/2/25 16:43	5/1/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	25	S.dm	-40,323	67.02	-602		1,571	I
5/2/25 16:38	5/1/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	10	17	P.d	2,818	24.69	114	18	740	D
5/2/25 16:31	5/1/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	6	35	M.d	57,894	221.55	261		78	D
5/2/25 16:31	5/1/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	6	35	S.d	-57,894	221.55	-261		78	D
5/2/25 16:18	4/30/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	8	11	M.dm	6,187	84.21	73	138	127	D
5/2/25 16:17	5/1/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	6	21	M.dm	4,539	13.58	334	49	1,015	D
5/2/25 16:17	5/1/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	6	21	S.dm	-4,539	13.58	-334		1,015	D
5/2/25 10:29	12/18/24	PRTA	Prothena Corp Public Ltd Co	L2	Health	Drug	Pharmaceutical Preparations	1	1	P.m	2,750	13.26	207	29	927	M
5/1/25 20:59	4/29/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	6	12	M.d	3,634	2.50	1,452	5	32,274	D
5/1/25 20:59	4/29/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	6	12	S.d	-3,634	2.50	-1,452		32,274	D
5/1/25 19:23	4/30/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	8	M.dm	0	0.00	33	6	571	D
5/1/25 19:07	4/30/25	ACRV	Acrivon Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	1	2	S.m	-3,763	1.67	-2,257		3,841	I
5/1/25 18:26	4/29/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	6	37	M.dm	11,334	17.13	662		433	D
5/1/25 18:26	4/29/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	6	37	S.dm	-11,334	17.13	-662		433	D
5/1/25 16:53	4/29/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	46	M.dm	11,569	29.21	396		392	D
5/1/25 16:53	4/29/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	46	S.dm	-11,569	29.21	-396		392	D
5/1/25 16:45	4/29/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	14	M.dm	11,687	46.54	251	14	2,004	D
5/1/25 16:45	4/29/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	14	S.dm	-11,687	46.54	-251		2,004	D
4/30/25 18:59	4/28/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	18	M.d	1,385	15.65	89	4	2,346	D
4/30/25 18:59	4/28/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	18	S.d	-1,385	15.65	-89		2,346	D
4/30/25 17:07	4/30/25	ZNTL	Zentalis Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	8	8	P.d	304	1.75	174	8	2,356	D
4/30/25 16:45	4/28/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	5	9	M.d	4,897	31.26	157	26	768	D
4/30/25 16:17	3/27/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-9	1.05	-9	0	14,237	I
4/30/25 16:15	4/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	6	17	S.d	-591	10.72	-55		4,258	D
4/29/25 18:14	4/25/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	13	19	P.d	412	1.18	351	53	1,009	D
4/29/25 16:33	4/29/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	6	38	S.d	-10,382	35.09	-296		746	D
4/29/25 06:14	4/25/25	GLSI	Greenwich Lifesciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	P	165	9.11	18	0	5,571	D
4/28/25 18:22	4/24/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	28	M.dm	30,239	43.09	702	38	2,561	D
4/28/25 18:22	4/24/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	28	S.dm	-30,239	43.09	-702		2,561	D
4/28/25 07:07	2/7/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	P	322	7.15	45	2	1,985	D
4/25/25 19:01	3/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	12	P.d	38,583	13.45	2,869	12	27,649	I
4/25/25 16:01	3/24/25	GYRE	Gyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	20	M.dm	1,354	1.85	731	26	3,552	D
4/24/25 16:40	4/23/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	10	S	-171	4.71	-36		1,535	D
4/24/25 16:28	4/22/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	15	S.d	-11,902	25.61	-465		6,426	I
4/24/25 16:06	4/22/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	9	S.m	-769	8.30	-93		2,358	D
4/23/25 18:00	4/21/25	TBPH	Theravance Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	1	1	S	-36	9.00	-4		370	D
4/22/25 21:00	4/21/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	2	10	M.dm	24,872	6.90	3,603		1,291	D
4/22/25 21:00	4/21/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	2	10	S.dm	-24,872	6.90	-3,603		1,291	D
4/22/25 21:00	4/18/25	AMRN	Amarin Corp Plcuk	X0	Health	Drug	Pharmaceutical Preparations	9	9	M.dm	0	0.00	12	17	83	D
4/22/25 17:38	4/30/24	VREO	Vireo Growth Inc.	A1	Health	Drug	Pharmaceutical Preparations	2	8	P.dm	20,262	0.6182	32,776	16	237,654	D
4/22/25 07:01	4/17/25	PEPG	Pepgen Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	P	66	1.22	54	87	117	D
4/21/25 17:00	4/18/25	SIGA	Siga Technologies Inc	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	0	0.00	14	56	38	D
4/21/25 16:05	4/17/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	2	5	M.d	1,000	17.04	59		53	D
4/21/25 16:04	4/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	S	-29	1.50	-19		2,424	D
4/18/25 15:17	4/16/25	ZYME	Zymeworks Inc.		Health	Drug	Pharmaceutical Preparations	1	7	P.m	25,436	12.06	2,108	13	17,828	I
4/17/25 16:05	4/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	5	5	M.d	0	0.00	12	1	2,039	D
4/17/25 16:05	1/30/25	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	50,091	8.74	5,730	40	20,233	I
4/17/25 06:10	4/15/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	9	P.m	119	0.8340	143	11	1,492	D
4/16/25 18:00	4/15/25	VTRS	Viatris Inc	DE	Health	Drug	Pharmaceutical Preparations	16	17	M.dm	0	0.00	1,980	257	2,752	D
4/16/25 17:12	4/14/25	BGNE	Beigene, Ltd.		Health	Drug	Pharmaceutical Preparations	6	27	M.dm	352,732	74.96	4,706	7	73,887	D
4/16/25 17:12	4/14/25	BGNE	Beigene, Ltd.		Health	Drug	Pharmaceutical Preparations	6	27	S.dm	-352,732	74.96	-4,706		73,887	D
4/16/25 17:00	4/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.m	-336	10.17	-33		485	D
4/16/25 16:35	4/15/25	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.dm	2,918	11.84	246	3	9,679	D
4/16/25 09:34	3/4/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-701	94.65	-7		59	D
4/15/25 17:30	3/31/25	ASMB	Assembly Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-15	9.85	-1		49	D
4/15/25 16:31	4/14/25	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	10	M.d	829	16.16	51	65	131	D
4/15/25 16:31	4/14/25	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	10	S.d	-829	16.16	-51		131	D
4/15/25 16:30	4/13/25	CELU	Celularity Inc	DE	Health	Drug	Pharmaceutical Preparations	4	7	M.d	0	0.00	49	180	77	D
4/15/25 14:02	4/10/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	P.m	106	1.08	98	3	3,758	D
4/15/25 12:50	4/2/25	NBY	Novabay Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	7	P.m	314	0.6251	502	97	1,020	D
4/15/25 07:59	4/14/25	TXMD	Therapeuticsmd, Inc.	NV	Health	Drug	Pharmaceutical Preparations	4	7	P.dm	3	0.0761	37	27	172	D
4/14/25 19:26	4/11/25	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	226	9.72	23	21	133	D
4/14/25 18:23	4/11/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	8	21	S.dm	-5,041	18.56	-272		1,018	D
4/14/25 17:58	4/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	6	30	M.dm	44,266	46.72	947	40	3,323	D
4/14/25 17:58	4/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	6	30	S.dm	-44,266	46.72	-947		3,323	D
4/14/25 17:17	4/11/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	7	24	M.dm	20,357	23.50	866		737	D
4/14/25 16:17	3/19/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	8	S.d	-652	60.61	-11		245	D
4/14/25 16:13	4/10/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	5	7	S.d	-737	13.69	-54		881	D
4/11/25 21:57	4/4/25	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	2	2	M.d	9,479	9.64	984	21	5,693	D
4/11/25 21:45	4/9/25	OSTX	Os Therapies Inc	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-366	2.29	-160		2,770	I
4/11/25 18:20	4/9/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.dm	-9,908	12.50	-793		4,062	D
4/11/25 17:22	4/1/25	PCSA	Processa Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	M	0	0.00	61	16	435	D
4/11/25 17:22	4/9/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	16	P.dm	3,552	8.32	427	8	5,789	I
4/11/25 13:23	4/10/25	GOVX	Geovax Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	P	34	1.03	33	92	68	D
4/10/25 19:06	4/9/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	P	101	20.20	5	3	197	M
4/10/25 17:07	4/10/25	OPK	Opko Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	P.d	1,237	1.61	767	0	247,698	I
4/10/25 16:15	4/8/25	ACUT	Accustem Sciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.m	104	0.5428	191	4	4,911	I
4/10/25 16:02	4/8/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	16	M.d	1,217	9.25	132	53	379	D
4/10/25 16:02	4/10/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	16	S.d	-1,217	9.25	-132		379	D
4/10/25 08:39	4/8/25	MBX	Mbx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	P.dm	4,621	10.53	439	22	2,450	D
4/9/25 16:44	4/7/25	XOMA	Xoma Royalty Corp		Health	Drug	Pharmaceutical Preparations	3	5	P.m	960	25.01	38	86	83	D
4/8/25 21:36	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S.ad	-3,824	24.85	-154		15,023	I
4/8/25 21:30	4/4/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.m	987	1.65	600	1	58,981	D
4/8/25 20:22	4/7/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	16	M.dm	41,652	53.05	785	999%	838	D
4/8/25 19:24	4/4/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	9	M.d	1,054	4.39	240	6	4,447	D
4/8/25 19:24	4/4/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	9	S.d	-1,054	4.39	-240		4,447	D
4/8/25 17:32	4/4/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.m	-12	2.94	-4		17	D
4/8/25 17:01	4/7/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-149	7.03	-21		185	D
4/8/25 16:45	4/7/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	8	M.dm	2,658	8.31	320		218	D
4/8/25 16:45	4/7/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	8	S.dm	-2,658	8.31	-320		218	D
4/8/25 16:41	4/7/25	DMAC	Diamedica Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	2	2	M.d	94	2.30	41	6	752	D
4/8/25 08:10	4/4/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	6	10	M.dm	1,689	27.19	62	46	196	D
4/7/25 21:55	4/3/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	M.d	439	0.3130	1,401	22	7,800	D
4/7/25 18:43	4/3/25	ALDX	Aldeyra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-4,828	1.42	-3,400		5,876	I
4/7/25 17:18	4/3/25	IBO	Impact Biomedical Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	S	-174	0.4950	-352	-100	0	I
4/7/25 16:48	4/3/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	7	28	M.dm	9,612	16.03	600	410	746	D
4/7/25 16:48	4/4/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	7	28	S.dm	-9,612	16.03	-600		746	D
4/7/25 16:11	4/4/25	PRLD	Prelude Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.dm	651	0.6911	941	29	4,224	D
4/4/25 19:42	3/7/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	12	M.dm	20,908	19.88	1,052	476	1,273	D
4/4/25 19:42	3/7/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	12	S.dm	-20,908	19.88	-1,052		1,273	D
4/4/25 19:27	4/2/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.d	-1,167	25.79	-45		1,786	D
4/4/25 17:35	4/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	6	6	S.m	-85	7.73	-11		838	D
4/4/25 16:34	4/3/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	42	3.28	13	12	121	D
4/4/25 16:30	4/2/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	M.d	1,556	12.55	124	9	1,571	D
4/4/25 16:18	4/4/25	BFRG	Bullfrog Ai Holdings, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-74	1.48	-50		2,348	D
4/4/25 16:13	4/2/25	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.dm	7,367	5.80	1,271	13	11,412	D
4/4/25 13:38	3/3/25	CPIX	Cumberland Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	4	4	P.m	7	5.21	1	0	6,058	D
4/4/25 10:54	4/2/25	ERNA	Eterna Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	394	0.1046	3,768	23	20,402	D
4/4/25 07:30	4/3/25	APRE	Aprea Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	10	1.84	6	2	347	D
4/3/25 19:27	4/2/25	CKPT	Checkpoint Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.m	-447	3.69	-121		5,234	D
4/3/25 18:06	4/1/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	7	7	M.d	365	12.14	30	4	722	D
4/3/25 18:05	4/1/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.m	230	6.76	34	38	125	I
4/3/25 17:32	2/3/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	4	9	S.dm	-4,682	136.40	-34		607	D
4/3/25 17:00	4/1/25	VERV	Verve Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	M.d	100	0.9713	103	10	1,099	D
4/3/25 17:00	4/2/25	VERV	Verve Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	S.d	-100	0.9713	-103		1,099	D
4/3/25 16:30	4/2/25	SYBX	Synlogic, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-3	1.32	-2		13	D
4/3/25 16:30	4/1/25	BPMC	Blueprint Medicines Corp	DE	Health	Drug	Pharmaceutical Preparations	11	17	S.dm	-8,021	84.85	-95		805	D
4/3/25 16:30	4/2/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	281	3.54	79	13	683	D
4/3/25 16:28	4/2/25	TLPH	Talphera, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.dm	131	0.5983	219	75	512	D
4/3/25 16:27	4/1/25	INZY	Inozyme Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	8	0.2321	34	468	41	D
4/3/25 16:27	4/2/25	INZY	Inozyme Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-8	0.2321	-34		41	D
4/3/25 16:21	4/2/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-2	0.1106	-18		2,773	D
4/3/25 16:21	4/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	15	S.dm	-2,518	12.77	-197		1,997	D
4/3/25 16:17	4/2/25	UBX	Unity Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	S.d	-145	1.04	-139		319	D
4/3/25 16:15	4/1/25	ACRS	Aclaris Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	0	0.00	163	9	1,935	D
4/3/25 16:15	4/1/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-426	13.44	-32		7	D
4/2/25 20:44	4/1/25	ZTS	Zoetis Inc.		Health	Drug	Pharmaceutical Preparations	18	39	M.d	390	6.02	65	32	265	D
4/2/25 18:48	4/1/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-16	4.44	-4		75	D
4/2/25 17:45	3/31/25	OGN	Organon & Co.		Health	Drug	Pharmaceutical Preparations	10	10	M.d	0	0.00	304	65	776	D
4/2/25 17:22	3/31/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	14	S.d	-498	3.03	-164		7,420	D
4/2/25 17:03	4/1/25	FBRX	Forte Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	0	0.00	2	1	111	D
4/2/25 17:00	3/31/25	ABBV	Abbvie Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	M.dm	66,781	184.95	361	210	533	D
4/2/25 17:00	3/31/25	ABBV	Abbvie Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	S.dm	-66,781	184.95	-361		533	D
4/2/25 16:37	2/27/25	BNTC	Benitec Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	12,112	12.51	968	474	1,173	D
4/2/25 16:12	4/1/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	9	17	S.dm	-47,284	5.81	-8,138		100,080	D
4/2/25 16:03	3/31/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	M.dm	261	2.00	130	86	281	D
4/2/25 15:46	3/31/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	P	448	0.5828	769	18	5,132	D
4/1/25 21:55	3/28/25	LPTX	Leap Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	7	M.d	0	0.00	168	8	2,269	D
4/1/25 20:06	3/28/25	AVTX	Avalo Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	8	M.d	0	0.00	108		84	D
4/1/25 15:52	3/31/25	RZLT	Rezolute, Inc.	NV	Health	Drug	Pharmaceutical Preparations	4	5	P.d	5,159	3.97	1,299	19	7,972	D
4/1/25 07:00	3/31/25	SVRA	Savara Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	416	2.78	150	6	2,514	D
3/31/25 20:05	3/28/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	10	P.dm	1,002	2.23	450		447	D
3/31/25 19:17	3/31/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-120	4.78	-25		1,355	D
3/31/25 16:34	3/31/25	AYTU	Aytu Biopharma, Inc	DE	Health	Drug	Pharmaceutical Preparations	3	3	M.d	20	1.27	15	14	126	D
3/28/25 18:59	3/27/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	6	S	-2,164	13.20	-164		1,179	D
3/28/25 17:54	3/27/25	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	M.d	2,391	7.49	319	56	890	D
3/28/25 16:00	3/26/25	ATOS	Atossa Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	7	0.7000	10	999%	10	D
3/27/25 16:15	3/27/25	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	2	0.0502	31	19	194	D
3/27/25 09:56	3/17/25	ZOM	Zomedica Corp.	A0	Health	Drug	Pharmaceutical Preparations	8	10	P	375	0.0656	5,721	29	25,224	I
3/27/25 07:30	3/26/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	P.d	27	0.7299	36	18	238	D
3/26/25 19:01	3/24/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	4	13	S.d	-132	3.70	-36		1,109	D
3/26/25 17:41	12/26/24	XCUR	Exicure, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	8,700	3.00	2,900	669	3,333	D
3/26/25 17:04	3/24/25	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	6	20	M.d	870	2.34	371	405	463	D
3/26/25 17:04	3/24/25	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	6	20	S.d	-870	2.34	-371		463	D
3/26/25 16:30	3/25/25	TRVI	Trevi Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	934	4.45	210	69	512	D
3/26/25 16:30	3/25/25	TRVI	Trevi Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-934	4.45	-210		512	D
3/25/25 16:10	3/21/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	7	23	S.dm	-12,239	179.46	-68		253	D
3/25/25 16:10	3/24/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	7	23	M.dm	12,239	179.46	68	37	253	D
3/25/25 09:00	3/24/25	FGEN	Fibrogen Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.m	156	0.3499	445	89	947	D
3/24/25 21:00	3/21/25	ATAI	Atai Life Sciences N.V.	P7	Health	Drug	Pharmaceutical Preparations	6	12	S.d	-25,521	1.93	-13,245		44,874	D
3/24/25 17:06	3/20/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	3	11	S.dm	-5,847	28.11	-208		426	D
3/24/25 16:39	3/20/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.m	-13	6.43	-2	0	562	D
3/24/25 16:33	3/21/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M	325	7.16	45		24	D
3/24/25 16:33	3/21/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-325	7.16	-45		24	D
3/21/25 21:00	3/20/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	4	6	M.dm	3,123	4.36	717	230	1,030	D
3/21/25 21:00	3/20/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	4	6	S.dm	-3,123	4.36	-717		1,030	D
3/21/25 17:31	3/20/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	1	1	S	-217	5.43	-40		1,354	D
3/20/25 19:38	3/19/25	BMRN	Biomarin Pharmaceutical Inc	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-686	70.91	-10		105	D
3/20/25 16:34	3/18/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-48	0.5990	-80		1,794	D
3/19/25 18:47	3/18/25	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-12	4.42	-3	0	711	D
3/19/25 18:11	3/17/25	SLRN	Acelyrin, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-69	2.74	-25		915	D
3/19/25 17:40	3/18/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	18	S.dm	-7,940	23.80	-334		4,115	D
3/19/25 16:49	3/17/25	TSVT	2Seventy Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-80,103	4.93	-16,248		1,820	D
3/19/25 15:31	3/18/25	NIKA	Nika Pharmaceuticals, Inc	CO	Health	Drug	Pharmaceutical Preparations	1	1	S	-500	0.2500	-2,000	0	455,590	D
3/19/25 14:48	3/18/25	OPTN	Optinose, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	S	-55	5.31	-10		226	D
3/19/25 08:06	3/18/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-840	15.42	-54		1,543	D
3/18/25 19:10	3/14/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-26	1.23	-21		622	D
3/18/25 18:45	3/17/25	VRCA	Verrica Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-3	0.6501	-4		176	D
3/18/25 18:35	3/14/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	1,453	9.18	158		0	D
3/18/25 18:35	3/14/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-1,453	9.18	-158	-100	0	D
3/18/25 16:15	3/17/25	ALT	Altimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	P.dm	58	0.4827	120	30	521	D
3/18/25 12:27	3/17/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-155	25.30	-6		351	D
3/17/25 18:38	3/14/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	7	7	M.d	0	0.00	699	0	185,621	I
3/17/25 17:14	3/13/25	NGNE	Neurogene Inc.		Health	Drug	Pharmaceutical Preparations	1	1	S	-76	16.94	-5		72	D
3/17/25 16:09	3/13/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	6	21	S	-18,923	483.40	-39		217	D
3/17/25 06:01	3/14/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	554	12.76	43	10	482	D
3/14/25 20:03	3/14/25	ETST	Earth Science Tech, Inc.	FL	Health	Drug	Pharmaceutical Preparations	4	4	P	41	0.1493	272	0	136,893	D
3/14/25 16:30	3/12/25	RPTX	Repare Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	4	4	S	-42	1.14	-37		595	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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