Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
12/12/25 20:30	12/11/25	AARD	Aardvark Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sun Nelson	CA	O	CFO	P	43	14.40	3	3	108	D
12/12/25 20:30	12/11/25	AARD	Aardvark Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lee Tien-Li	CA	DOT	CEO	P	101	14.49	7	0	3,026	D
12/12/25 18:00	12/12/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chaudhary Zuraiz	CA	O	See Rema	P	9	3.50	3	25	13	D
12/12/25 17:17	12/12/25	IMVT	Immunovant, Inc.	D0	Health	Drug	Pharmaceutical Preparations	Roivant Sciences Ltd.	X0	DT		P	350,000	21.00	16,667	17	113,317	D
12/12/25 08:39	12/10/25	SXTP	60 Degrees Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dow Geoffrey S	DC	DO	P,CEO	P.m	12	0.9415	13	35	50	D
12/12/25 07:16	12/11/25	FBLG	Fibrobiologics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Garcia Ruben A	TX	O	GC	P	48	0.3400	140	New	140	D
12/11/25 08:31	12/10/25	APRE	Aprea Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Duey Marc	PA	D		P.d	25	1.17	21	9	257	D
12/11/25 08:31	12/10/25	APRE	Aprea Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hamill John P.	PA	O	SrVP,CFO	P.d	6	1.17	5	22	28	D
12/10/25 18:49	12/10/25	IMMX	Immix Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rachman Ilya M	CA	DO	CEO,CB	P	5	6.67	1	0	1,142	D
12/10/25 18:48	12/8/25	TENX	Tenax Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rich Stuart	NC	DO	Chief Me	P.dm	51	10.16	5	65	13	M
12/10/25 18:47	12/10/25	IMMX	Immix Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Morris Gabriel S	CA	DO	CFO	P.d	5	6.58	1	0	742	M
12/9/25 19:13	12/5/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	Akkaraju Srinivas	CA	D		P	1,834	9.84	186	3	5,757	I
12/9/25 16:51	12/5/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Stan	IL	D		P	16	1.20	14	1	1,369	I
12/9/25 16:36	12/5/25	MRVI	Maravai Lifesciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lucier Gregory T	CA	D		P.m	369	3.69	100	61	265	D
12/9/25 16:12	12/5/25	SLGL	Sol-Gel Technologies Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		P.m	29	39.61	1	0	382	I
12/8/25 20:05	12/8/25	ANVS	Annovis Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hoffman Michael B	PA	D		P	194	4.31	45	2	2,798	D
12/8/25 17:15	11/17/25	DMAC	Diamedica Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Stahlberg Jan	V7	T		P.m	7,631	7.19	1,061	14	8,826	I
12/8/25 16:30	12/4/25	XOMA	Xoma Royalty Corp	NV	Health	Drug	Pharmaceutical Preparations	Hughes Owen	CA	DO	CEO	P	2,505	25.05	100	99	201	D
12/8/25 16:30	12/4/25	CBIO	Crescent Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	Fairmount Funds Management LLC	PA	DT		P.d	18,238	13.41	1,360	98	2,748	I
12/8/25 16:07	12/4/25	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Barabe Timothy C	MD	D		P	206	6.86	30	123	54	D
12/8/25 07:00	12/5/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Agah Ramtin	CA	DO	Chief Me	P	10	0.9600	10	1	766	D
12/5/25 17:46	12/2/25	TENX	Tenax Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rich Stuart	NC	DO	Chief Me	P.dm	46	9.12	5	188	8	M
12/4/25 20:11	12/2/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	Akkaraju Srinivas	CA	D		P.m	2,040	7.79	262	5	5,571	I
12/4/25 16:15	12/2/25	BMEA	Biomea Fusion, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hitchcock Michael J.M.	CA	DO	Interim	P	99	0.9918	100	667	115	D
12/4/25 07:31	11/25/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vitoc Vlad	IL	DOT	CEO	P.a	10	0.9661	11	1	1,042	D
12/4/25 07:30	11/26/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vitoc Vlad	IL	DOT	CEO	P.am	80	1.11	72	7	1,114	D
12/3/25 17:39	12/1/25	SLGL	Sol-Gel Technologies Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		P.m	258	37.53	7	2	381	I
12/3/25 16:30	12/1/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Choi Jung	CA	D		P	138	4.19	33	New	33	I
12/3/25 16:30	12/1/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Carson William H.	CA	D		P	18	4.47	4	9	50	D
12/2/25 16:15	11/28/25	BMEA	Biomea Fusion, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Erdtmann Rainer M	CA	DO	See Rema	P.m	55	1.09	50	2	2,543	D
12/1/25 18:09	11/26/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	Akkaraju Srinivas	CA	D		P.m	1,311	7.55	174	3	5,309	I
12/1/25 16:15	11/26/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Morikis John G	NJ	D		P	258	206.15	1	209	2	D
12/1/25 09:07	11/28/25	KTTA	Pasithea Therapeutics Corp.	DE	Health	Drug	Pharmaceutical Preparations	Steinman Lawrence	FL	D		P	100	0.7500	133	201	200	D
12/1/25 08:56	11/28/25	KTTA	Pasithea Therapeutics Corp.	DE	Health	Drug	Pharmaceutical Preparations	Marques Tiago	FL	DO	CEO	P	25	0.7500	33	83	73	D
12/1/25 08:54	11/28/25	KTTA	Pasithea Therapeutics Corp.	DE	Health	Drug	Pharmaceutical Preparations	Dumesnil Simon	FL	D		P	25	0.7500	33	999%	36	D
12/1/25 06:20	11/28/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vitoc Vlad	IL	DOT	CEO	P.m	80	1.11	72	7	1,063	D
12/1/25 06:18	11/26/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Luput Cristian	IL	D		P.m	42	1.10	38	10	438	D
12/1/25 06:14	11/26/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Stan	IL	D		P	16	1.04	15	1	1,364	I
11/28/25 17:38	11/25/25	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Paulson & Co. Inc.	NJ	T		P	15,625	6.25	2,500	4	73,256	I
11/28/25 09:00	11/26/25	COCP	Cocrystal Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DT		P	4	0.9938	4	0	1,731	I
11/28/25 06:52	11/25/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Luput Cristian	IL	D		P	10	0.9785	10	3	399	D
11/28/25 06:48	11/25/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vitoc Vlad	IL	DOT	CEO	P	10	0.9661	11	1	1,041	D
11/28/25 06:05	11/25/25	GLSI	Greenwich Lifesciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Snehal	TX	DOT	CEO,CFO	P	39	8.37	5	0	5,588	D
11/26/25 16:43	11/24/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Stan	IL	D		P.m	25	0.9840	25	2	1,349	I
11/26/25 16:05	11/24/25	SLGL	Sol-Gel Technologies Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		P.m	38	39.97	1	0	374	I
11/26/25 14:58	11/26/25	ABCL	Abcellera Biologics Inc.	A1	Health	Drug	Pharmaceutical Preparations	Montalbano John S.	A1	D		P	178	3.57	50	28	226	D
11/25/25 21:00	11/24/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Golden Arthur F	CA	D		P	34	3.44	10	19	61	D
11/25/25 20:17	11/25/25	COCP	Cocrystal Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DT		P	19	0.9406	20	1	1,727	I
11/25/25 19:00	11/25/25	VRCA	Verrica Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rosenberg Noah L.	PA	O	CMO	P.d	10	4.24	2	New	2	D
11/25/25 19:00	11/25/25	VRCA	Verrica Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kirby John J.	PA	O	Interim	P.d	15	4.24	4	65	9	D
11/25/25 19:00	11/25/25	VRCA	Verrica Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zawitz David	PA	O	COO	P.d	42	4.24	10	91	21	D
11/25/25 19:00	11/25/25	VRCA	Verrica Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rieger Jayson	PA	DO	CEO,P	P.d	400	4.24	94	106	183	D
11/25/25 19:00	11/25/25	VRCA	Verrica Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Manning Paul B	VA	DT		P.d	17,505	4.24	4,126	108	7,932	M
11/25/25 18:59	11/24/25	ANVS	Annovis Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hoffman Michael B	PA	D		P.a	160	4.08	39	1	2,753	D
11/25/25 16:15	11/21/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vitoc Vlad	IL	DOT	CEO	P.m	12	0.9786	12	1	1,031	D
11/25/25 16:06	11/24/25	SAVA	Cassava Sciences Inc	DE	Health	Drug	Pharmaceutical Preparations	Anderson Robert Eugene Jr	TX	D		P	25	2.90	9	New	9	D
11/25/25 16:02	11/21/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	Foresite Capital Management VI LLC	CA	T		P	533	7.38	72	0	15,778	I
11/25/25 16:02	11/21/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tananbaum James B.	CA	DT		P	533	7.38	72	0	15,778	I
11/25/25 16:01	11/21/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	Foresite Labs, LLC	CA	T		P	533	7.38	72	0	15,778	I
11/25/25 12:26	11/24/25	ANVS	Annovis Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hoffman Michael B	PA	D		P	160	4.08	39	1	2,743	D
11/24/25 21:10	11/21/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Heshmatpour Amir F	CA	DOT	P	P.m	185	6.16	30	0	10,494	D
11/24/25 18:50	11/20/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	Akkaraju Srinivas	CA	D		P	905	7.20	126	3	5,135	I
11/24/25 18:00	11/21/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Agah Ramtin	CA	DO	Chief Me	P.m	18	0.8000	22	3	756	D
11/24/25 17:46	11/20/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Neman-Ebrahim Yousha	CA	O	Chief Cl	P	7	6.69	1	1	134	D
11/24/25 17:08	11/20/25	SLRX	Salarius Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hanish Arnold C	TX	D		P	4	0.7481	5	999%	5	I
11/24/25 16:09	11/20/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	T		P	262	9.07	29	1	4,691	I
11/24/25 16:02	11/20/25	SAVA	Cassava Sciences Inc	DE	Health	Drug	Pharmaceutical Preparations	Barry Richard	TX	DO	P,CEO	P	414	2.76	150	19	938	I
11/24/25 12:54	11/21/25	PHIO	Phio Pharmaceuticals Corp.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Robert J	PA	DO	CB,P,CEO	P	6	1.14	5	2	281	D
11/24/25 07:13	11/21/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Golden Arthur F	CA	D		P	59	2.87	21	68	51	D
11/21/25 21:52	11/20/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Satter Muneer A	CA	D		P.m	3,601	4.38	823	9	9,729	I
11/21/25 19:57	11/21/25	ANVS	Annovis Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hoffman Michael B	PA	D		P	70	3.50	20	1	2,714	D
11/21/25 18:35	11/20/25	SILO	Silo Pharma, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Weisblum Eric	FL	DO	CEO	P.m	1	0.3675	2	1	212	D
11/21/25 17:43	11/20/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chaudhary Zuraiz	CA	O	See Rema	P.m	7	2.89	2	32	10	D
11/21/25 17:07	11/21/25	OPK	Opko Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	769	1.33	580	0	250,403	I
11/21/25 16:05	11/20/25	SLGL	Sol-Gel Technologies Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		P	207	35.83	6	2	373	I
11/21/25 08:45	11/19/25	SLS	Sellas Life Sciences Group, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kalin Katherine Bach	NY	D		P	101	1.59	63	155	104	D
11/20/25 18:38	11/18/25	TENX	Tenax Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Giordano Christopher Thomas	NC	DO	CEO	P.dm	20	7.68	3	New	3	D
11/20/25 18:16	11/17/25	TENX	Tenax Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Almenoff June Sherie	NC	D		P.am	15	7.50	2	New	2	I
11/20/25 18:10	11/20/25	OPK	Opko Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	771	1.33	580	0	249,823	I
11/20/25 17:39	11/19/25	SAVA	Cassava Sciences Inc	DE	Health	Drug	Pharmaceutical Preparations	Barry Richard	TX	DO	P,CEO	P	202	2.75	73	10	788	I
11/20/25 16:42	11/20/25	SLRX	Salarius Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rosenblum Mark J	TX	O	EVP Fina	P	16	0.8000	20	999%	20	D
11/20/25 16:00	11/18/25	SILO	Silo Pharma, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Weisblum Eric	FL	DO	CEO	P.m	5	0.4039	12	6	210	D
11/20/25 16:00	11/19/25	LITS	Lite Strategy, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flynn James P	CA	D		P	23	1.88	12	68	30	D
11/20/25 07:00	11/18/25	ITRM	Iterum Therapeutics Plc	L2	Health	Drug	Pharmaceutical Preparations	Dunne Michael W.	L2	D		P	2	0.3652	6	3	241	D
11/19/25 21:00	11/17/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Satter Muneer A	CA	D		P.m	5,055	3.37	1,500	20	8,906	I
11/19/25 20:54	11/17/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	Foresite Labs, LLC	CA	T		P.m	3,095	6.09	508	3	15,706	I
11/19/25 20:52	11/17/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	Foresite Capital Management VI LLC	CA	T		P.m	3,095	6.09	508	3	15,706	I
11/19/25 20:51	11/17/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tananbaum James B.	CA	DT		P.m	3,095	6.09	508	3	15,706	I
11/19/25 20:46	11/17/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	Akkaraju Srinivas	CA	D		P.m	1,530	6.34	241	5	5,009	I
11/19/25 19:01	11/17/25	TENX	Tenax Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McGauley Thomas	NC	O	Interim	P	58	7.27	8	New	8	M
11/19/25 18:43	11/17/25	TENX	Tenax Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Almenoff June Sherie	NC	D		P.dm	15	7.50	2	New	2	D
11/19/25 17:02	11/19/25	OPK	Opko Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	759	1.31	580	0	249,243	I
11/19/25 12:47	11/18/25	PHIO	Phio Pharmaceuticals Corp.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Robert J	PA	DO	CB,P,CEO	P	6	1.27	5	2	276	D
11/19/25 07:46	11/17/25	CRVO	Cervomed Inc.	DE	Health	Drug	Pharmaceutical Preparations	Winton Matthew	MA	O	Chief Co	P.m	41	8.29	5	50	15	D
11/19/25 07:45	11/17/25	CRVO	Cervomed Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gregoire Sylvie	MA	DT		P	183	8.46	22	1	1,497	M
11/19/25 07:45	11/17/25	CRVO	Cervomed Inc.	DE	Health	Drug	Pharmaceutical Preparations	Elder William Robert	MA	O	CFO,GC,S	P.m	29	8.36	4	39	13	D
11/19/25 07:45	11/17/25	CRVO	Cervomed Inc.	DE	Health	Drug	Pharmaceutical Preparations	Alam John J	MA	DOT	CEO,P	P	183	8.46	22	1	1,497	M
11/18/25 17:30	11/14/25	RNTX	Rein Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Voss Capital, LP	TX	T		P	128	1.22	104	8	1,426	I
11/18/25 17:18	11/18/25	OPK	Opko Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	679	1.27	533	0	248,663	I
11/18/25 16:15	11/18/25	BIXT	Bioxytran, Inc	NV	Health	Drug	Pharmaceutical Preparations	Hoberman Alan M	PA	D		P	126	0.6000	210	50	626	D
11/18/25 07:44	11/14/25	ANVS	Annovis Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hoffman Michael B	PA	D		P	32	2.11	15	1	2,694	D
11/18/25 07:29	11/17/25	BHVN	Biohaven Ltd.	D8	Health	Drug	Pharmaceutical Preparations	Clark George C.	CT	O	VP,Chief	P	145	8.52	17	25	86	I
11/17/25 21:23	11/17/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chaudhary Zuraiz	CA	O	See Rema	P	9	3.62	3	50	8	D
11/17/25 16:59	11/13/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	Akkaraju Srinivas	CA	D		P	1,450	5.25	276	6	4,768	I
11/17/25 16:48	11/13/25	MRVI	Maravai Lifesciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brust Bernd	CA	DO	CEO	P	703	3.25	216	10	2,467	I
11/17/25 16:42	11/13/25	FGEN	Fibrogen Inc	DE	Health	Drug	Pharmaceutical Preparations	Wettig Thane	CA	DO	CEO	P.m	34	9.12	4	17	25	D
11/17/25 09:02	11/13/25	CRVO	Cervomed Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gregoire Sylvie	MA	DT		P.m	59	7.53	8	1	1,475	M
11/17/25 09:01	11/13/25	CRVO	Cervomed Inc.	DE	Health	Drug	Pharmaceutical Preparations	Alam John J	MA	DOT	CEO,P	P.m	59	7.53	8	1	1,475	M
11/17/25 09:01	11/14/25	CRVO	Cervomed Inc.	DE	Health	Drug	Pharmaceutical Preparations	Winton Matthew	MA	O	Chief Co	P	76	7.57	10	New	10	D
11/17/25 08:01	11/13/25	CATX	Perspective Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hunt Jonathan Robert	WA	O	Chief Ac	P	22	2.03	11	23	60	D
11/17/25 07:31	11/13/25	BHVN	Biohaven Ltd.	D8	Health	Drug	Pharmaceutical Preparations	Bailey Gregory	CT	D		P	3,000	7.50	400	25	2,020	D
11/17/25 07:30	11/13/25	BHVN	Biohaven Ltd.	D8	Health	Drug	Pharmaceutical Preparations	Childs John W	CT	D		P	25,000	7.50	3,333	51	9,877	I
11/17/25 07:30	11/13/25	BHVN	Biohaven Ltd.	D8	Health	Drug	Pharmaceutical Preparations	Coric Vlad	CT	DO	CEO	P	5,000	7.50	667	21	3,843	I
11/14/25 18:14	11/13/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Ra Capital Management, L.P.	MA	DT		P	7	6.69	1	0	18,232	I
11/14/25 10:45	11/12/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	Parker Geoffrey M.	MI	D		P	106	14.18	8	12	72	I
11/14/25 08:17	11/13/25	ZOMDF	Zomedica Corp.	A0	Health	Drug	Pharmaceutical Preparations	Klass Russell Kevin	MI	O	SVP,Sale	P	15	0.0970	150	3	5,784	D
11/14/25 08:00	11/12/25	CATX	Perspective Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Williamson Robert F III	WA	D		P	20	2.10	9	9	119	I
11/13/25 18:04	11/11/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fox Jonathan C	CO	D		P	199	18.64	11	82	24	D
11/13/25 17:27	11/11/25	MRVI	Maravai Lifesciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brust Bernd	CA	DO	CEO	P.m	809	3.23	251	13	2,251	I
11/13/25 16:05	11/12/25	OGN	Organon & Co.		Health	Drug	Pharmaceutical Preparations	Cox Carrie Smith	NJ	DO	Exec Cha	P	502	7.67	65	525	78	I
11/13/25 08:52	11/12/25	CRVO	Cervomed Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gregoire Sylvie	MA	DT		P	41	7.35	6	0	1,467	D
11/13/25 08:52	11/12/25	CRVO	Cervomed Inc.	DE	Health	Drug	Pharmaceutical Preparations	Elder William Robert	MA	O	CFO,GC,S	P	26	7.44	4	64	9	D
11/13/25 08:52	11/12/25	CRVO	Cervomed Inc.	DE	Health	Drug	Pharmaceutical Preparations	Alam John J	MA	DOT	CEO,P	P	41	7.35	6	0	1,467	D
11/12/25 17:34	11/10/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	T		P.m	1,353	7.60	178	4	4,665	I
11/12/25 16:33	11/10/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Grant Grady III	WA	D		P	20	1.49	14	999%	14	D
11/12/25 16:26	11/7/25	EVMN	Evommune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ra Capital Management, L.P.	MA	DT		P.d	20,000	16.00	1,250		784	I
11/12/25 16:25	11/7/25	EVMN	Evommune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lsp 7 Cooperative Ua	P7	T		P.d	25,000	16.00	1,563	46	4,930	D
11/12/25 16:24	11/7/25	EVMN	Evommune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Verduyn-Van Weegen Felice Isabel	CA	DT		P.d	25,000	16.00	1,563	46	4,930	I
11/12/25 09:19	10/28/25	ANVS	Annovis Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Maccecchini Maria-Luisa	PA	DO	P,CEO	P	200	2.05	98	9	1,212	D
11/12/25 09:18	10/28/25	ANVS	Annovis Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hoffman Michael B	PA	D		P	2,000	2.05	976	57	2,679	D
11/12/25 06:06	11/10/25	ZOMDF	Zomedica Corp.	A0	Health	Drug	Pharmaceutical Preparations	Klass Russell Kevin	MI	O	SVP,Sale	P	12	0.0980	120	2	5,634	D
11/12/25 06:05	11/7/25	GLSI	Greenwich Lifesciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Snehal	TX	DOT	CEO,CFO	P	89	8.43	11	0	5,584	D
11/10/25 21:51	11/7/25	BNTC	Benitec Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Suvretta Capital Management, LLC	NY	DT		P	20,000	13.50	1,481	438	1,820	I
11/10/25 17:21	11/7/25	ZOMDF	Zomedica Corp.	A0	Health	Drug	Pharmaceutical Preparations	Klass Russell Kevin	MI	O	SVP,Sale	P	0	0.0950	5	0	5,514	D
11/7/25 16:46	11/6/25	ZOMDF	Zomedica Corp.	A0	Health	Drug	Pharmaceutical Preparations	Klass Russell Kevin	MI	O	SVP,Sale	P	20	0.0800	253	5	5,509	D
11/6/25 08:01	11/5/25	NVCT	Nuvectis Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bentsur Ron	NJ	DOT	CB,CEO	P	29	5.72	5	0	3,526	D
11/6/25 08:00	11/5/25	NVCT	Nuvectis Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sanchez Juan	NJ	D		P	75	5.79	13	20	79	D
11/6/25 08:00	11/5/25	NVCT	Nuvectis Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaplan Matthew L.	NJ	D		P	64	5.84	11	10	125	D
11/6/25 07:30	11/5/25	RLMD	Relmada Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Shenouda Maged	FL	O	CFO	P	1,100	2.20	500	173	788	D
11/6/25 07:30	11/5/25	RLMD	Relmada Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Ence Chuck	FL	O	CAO,COO	P	299	2.20	136	51	404	D
11/6/25 07:30	11/5/25	RLMD	Relmada Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Traversa Sergio	FL	DO	CEO	P	600	2.20	273	27	1,273	D
11/6/25 07:30	11/5/25	RLMD	Relmada Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Kelly Paul Edward	FL	DO	COO	P	198	2.20	90	22	502	D
11/4/25 06:16	10/31/25	GLSI	Greenwich Lifesciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Snehal	TX	DOT	CEO,CFO	P	21	9.26	2	0	5,573	D
11/3/25 17:25	5/14/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nussdorf Glenn H	NY	DT		P.m	1,096	3.06	358	3	12,249	I
10/31/25 17:15	10/31/25	OPK	Opko Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	P	213	1.42	150	0	248,083	I
10/31/25 16:15	10/30/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Carson William H.	CA	D		P	13	3.17	4	10	46	D
10/30/25 16:31	10/28/25	MPLT	Maplight Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Novo Holdings A/S	G7	T		P.d	16,200	17.00	953	35	3,687	D
10/29/25 20:43	10/23/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chesed Abraham	CA	H	Board Ob	P	66	4.60	14	1	1,447	I
10/29/25 16:16	10/28/25	MLPT	Maplight Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Catalyst4, Inc.	CA	T		P.d	92,500	17.00	5,441	38	19,697	I
10/29/25 08:00	10/23/25	NVCT	Nuvectis Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mosseri Marlio Charles	N1	T		P.m	957	6.18	155	5	3,246	I
10/28/25 18:45	10/24/25	RNTX	Rein Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Voss Capital, LP	TX	T		P.m	423	1.38	306	30	1,322	I
10/27/25 21:30	10/23/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaplan Myron	NJ	D		P	276	11.02	25	12	231	D
10/27/25 19:24	10/23/25	RANI	Rani Therapeutics Holdings, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Imran Mir A	CA	DT		P.d	1,260	0.6050	2,083	9	24,818	D
10/27/25 16:30	10/23/25	VRDN	Viridian Therapeutics, Inc.De	DE	Health	Drug	Pharmaceutical Preparations	Fairmount Funds Management LLC	PA	DT		P	10,000	22.00	455	13	3,914	I
10/24/25 19:19	6/6/25	BOLT	Bolt Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nemec Sarah	CA	O	SVP,Fina	P	1	5.49	0	1	24	D
10/24/25 19:18	6/6/25	BOLT	Bolt Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quinn William P.	CA	DO	P,CEO,CF	P	1	5.49	0	0	42	D
10/23/25 21:06	10/21/25	SMMT	Summit Therapeutics Inc.		Health	Drug	Pharmaceutical Preparations	Xia Yu	FL	D		P	10,000	18.74	534	2	32,057	I
10/23/25 21:03	10/23/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chaudhary Zuraiz	CA	O	See Rema	P	25	4.95	5	New	5	D
10/23/25 21:01	10/23/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Golden Arthur F	CA	D		P	100	4.95	20	202	30	D
10/23/25 19:49	10/21/25	NEUP	Neuphoria Therapeutics Inc.	C3	Health	Drug	Pharmaceutical Preparations	Lynx1 Capital Management LP	PR	T		P	3,283	5.14	639	271	875	I
10/23/25 16:08	10/21/25	SMMT	Summit Therapeutics Inc.		Health	Drug	Pharmaceutical Preparations	Duggan Robert W	FL	DOT	Co-CEO	P	500	18.74	27	0	606,106	M
10/23/25 16:06	10/21/25	SMMT	Summit Therapeutics Inc.		Health	Drug	Pharmaceutical Preparations	Zanganeh Mahkam	FL	DOT	Co-CEO	P	500	18.74	27	0	606,106	I
10/21/25 17:43	10/20/25	MBX	Mbx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hawryluk P. Kent	IN	DO	P,CEO	P	273	13.64	20	2	950	I
10/20/25 16:44	10/17/25	MBX	Mbx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hoerter Steven L.	IN	D		P	265	13.25	20	New	20	I
10/20/25 09:11	10/17/25	GOVX	Geovax Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Spencer John N Jr	GA	D		P	5	0.5498	10	88	21	D
10/15/25 17:15	10/14/25	QNRX	Quoin Pharmaceuticals, Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Langer Dennis	VA	D		P.d	129	8.49	15	999%	15	D
10/15/25 16:32	10/6/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parkman Healthcare Partners LLC	CT	T		P	5	17.91	0	32	1	I
10/14/25 17:16	10/9/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nunn Jason Raleigh	PA	D		P	1,200	19.00	63	2	3,120	I
10/14/25 17:14	10/9/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sr One Capital Management, LLC	PA	T		P	2,400	19.00	126	3	5,038	I
10/14/25 08:59	10/9/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Enright Patrick G	MA	D		P	2,250	19.19	117	5	2,619	M
10/10/25 20:06	10/8/25	ACET	Adicet Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		P	5,000	1.00	5,000	207	7,421	I
10/9/25 17:24	10/7/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moulder Leon O Jr	MA	DO	See Rema	P	770	20.85	37	2	1,975	I
10/9/25 16:15	10/7/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fairmount Funds Management LLC	PA	D		P	6,008	19.00	316	17	2,209	I
10/9/25 15:37	9/13/24	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lu Hongbo	MA	D		P.m	6,000	18.63	322	New	322	I
10/9/25 09:01	10/8/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	Bodenstedt Matthias	V8	O	CFO	P	99	9.09	11	2	628	D
10/8/25 20:55	10/6/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parkman Healthcare Partners LLC	CT	T		P	5	17.91	0	32	1	I
10/7/25 08:56	10/3/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Feinberg Peter	MA	D		P	50	6.67	8	1	1,141	D
10/6/25 09:12	10/3/25	PMN	Promis Neurosciences Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Milbury Max A.	A6	H	Principa	P	15	0.4912	30	203	45	D
10/3/25 13:18	10/2/25	SNGX	Soligenix, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schaber Christopher J	NJ	DO	CB,CEO,P	P	20	1.32	15	999%	16	D
10/2/25 16:51	10/1/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Stan	IL	D		P.d	25	1.30	19	1	1,324	I
10/2/25 16:44	9/30/25	SAVA	Cassava Sciences Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Robert Christopher	TX	O	COO,Lega	P	40	2.91	14	New	14	D
10/2/25 16:17	9/30/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Carson William H.	CA	D		P	13	3.05	4	11	42	D
10/2/25 09:02	10/1/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Morales Mallory	MA	O	Chief Ac	P	2	6.39	0	1	28	D
10/2/25 08:57	10/1/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Neufeld Leah R	MA	O	CHIEF PE	P	5	6.38	1	4	23	D
10/2/25 08:52	10/1/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Bookman Michael	MA	O	GC,SECRE	P	7	6.83	1	26	5	D
10/1/25 13:07	9/30/25	PEPG	Pepgen Inc.	DE	Health	Drug	Pharmaceutical Preparations	Oxford Science Enterprises Plc	X0	H	Former 1	P	640	3.20	200	4	4,955	D
10/1/25 08:59	9/30/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Feinberg Peter	MA	D		P	53	7.03	8	1	1,134	D
9/30/25 16:59	9/26/25	MBX	Mbx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Heron Patrick J	CA	DT		P	12,000	18.00	667	15	5,219	I
9/30/25 16:35	9/26/25	PEPG	Pepgen Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ra Capital Management, L.P.	MA	DT		P	30,000	3.20	9,375	88	20,065	I
9/30/25 16:07	9/26/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Shah Rutul R	MD	O	COO	P	7	3.40	2	0	406	D
9/30/25 16:04	9/29/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Tennant Phil	MD	O	Chief Co	P	21	3.58	6	10	65	D
9/30/25 09:00	9/29/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Feinberg Peter	MA	D		P	36	7.18	5	0	1,126	D
9/26/25 17:01	9/25/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Thomasian Harry Jr.	MD	O	CFO	P.m	40	3.57	11	2	469	D
9/24/25 09:16	9/22/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Morrison Briggs	CT	D		P	227	7.57	30	65	76	D
9/23/25 16:06	9/22/25	SAVA	Cassava Sciences Inc	DE	Health	Drug	Pharmaceutical Preparations	Barry Richard	TX	DO	P,CEO	P	16	2.28	7	1	715	I
9/22/25 16:07	9/18/25	SAVA	Cassava Sciences Inc	DE	Health	Drug	Pharmaceutical Preparations	Barry Richard	TX	DO	P,CEO	P.m	535	2.25	238	51	708	I
9/22/25 09:35	9/18/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Roberts Eric W	CA	DOT	CHIEF BU	P	8	3.07	3	0	1,064	I
9/18/25 19:28	9/18/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Gline Matthew	X0	DO	CEO	P	50	15.07	3	0	17,287	D
9/18/25 16:36	9/16/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	Lewis Darwin	UT	D		P	5	10.85	0	0	117	D
9/18/25 16:23	9/16/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	Lettmann Jason	CA	DO	CEO	P.m	99	1.08	92	43	305	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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