Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
9/25/25 20:59	9/23/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	DT		7	S.dm	-1,098	2.49	-442		124	I
9/25/25 19:44	9/23/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	19	S.dm	-4,650	23.57	-197		1,117	I
9/25/25 19:42	9/23/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	20	S.dm	-4,175	23.14	-180		1,265	I
9/25/25 16:31	11/1/24	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Causey Christopher	MD	D		7	S.d	-4,345	341.62	-13		5	D
9/25/25 16:30	8/26/24	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	D		47	S.dm	-102,253	324.54	-315		647	D
9/24/25 20:35	12/16/24	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Waddill William D.	CA	D		7	S.dm	-1,836	42.20	-43		54	D
9/24/25 19:42	9/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saccomano Nicholas A	CO	DO	P,CEO	3	S.m	-3	2.87	-1		4	D
9/24/25 19:41	9/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leverone Jason A.	CO	O	CFO	3	S.m	-11	2.87	-4		13	D
9/24/25 19:00	2/3/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Bush Tia L	X0	O	Chief Te	4	S.dm	-2,549	20.69	-123		148	D
9/24/25 18:49	9/12/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		11	S.m	-1,456	2.77	-526		4,488	I
9/24/25 17:11	9/23/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Aryeh Jason	FL	D		1	S	-1,708	170.81	-10		126	D
9/24/25 16:30	9/22/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chacko Jacob	CA	DO	P,CEO	2	S.d	-1,554	10.38	-150		779	D
9/24/25 16:30	9/22/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Calkins Daniel	MA	O	CFO	11	S.m	-114	7.25	-16		114	D
9/24/25 16:14	8/6/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	10	S.dm	-21,710	40.56	-535		2,146	D
9/24/25 16:05	5/5/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Reed Elizabeth E	CA	O	GC,GC	6	S.d	-817	21.11	-39		90	D
9/24/25 06:35	9/22/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	25	S.dm	-122,067	375.30	-325		3	I
9/23/25 21:00	9/19/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	15	S.dm	-64,798	12.34	-5,251		1,654	D
9/23/25 17:32	9/22/25	XOMA	Xoma Royalty Corp	NV	Health	Drug	Pharmaceutical Preparations	Burns Thomas M.	CA	O	SVP,Fina	3	S.d	-715	29.06	-25		40	D
9/23/25 17:07	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	35	S.d	-7,641	49.98	-153		141	D
9/23/25 16:57	9/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	7	S.d	-4,225	41.23	-102		82	D
9/23/25 16:33	9/19/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	Versant Venture Capital Vi, L.P.	CA	T		3	S.m	-7,538	1.40	-5,376		6,410	M
9/22/25 19:49	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	O'Malley Brendan M.	OH	O	SVP,GC	3	S	-177	6.18	-29		378	D
9/22/25 19:00	9/22/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jacobson Mark L.	NY	O	COO	6	S.dm	-18,005	101.66	-177		6	D
9/22/25 18:32	9/9/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	Bendheim Jack	NJ	DOT	P,CEO	2	S.dm	-1,140	40.51	-28		78	I
9/22/25 17:25	9/19/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Barber Daniel	NJ	DO	P,CEO	1	S	-2	6.00	0	0	1,015	D
9/22/25 17:14	9/19/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Davis Krista	MN	O	SVP,CHRO	6	S	-561	73.54	-8		69	D
9/22/25 16:00	7/24/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		37	S.e	-2,847,834	865.04	-3,292		98,713	D
9/19/25 21:17	9/19/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunlop A. Sinclair	MA	D		3	S	-3,506	33.36	-105		302	I
9/19/25 20:46	9/18/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Kirk Randal J	VA	DT		1	S.dm	-18,654	3.73	-5,000		128,722	I
9/19/25 18:23	9/18/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Huizenga Theodore Alan	CA	O	SVP,Chie	4	S.d	-50	41.73	-1		50	D
9/19/25 16:49	9/19/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Olian Judy D.	MD	D		3	S	-1,972	375.59	-5		6	D
9/19/25 16:05	9/4/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ceesay Abraham	MA	DO	CEO	2	S	-2,075	26.34	-79		722	D
9/18/25 21:30	9/16/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harmon Cyrus	CA	D		6	S.m	-965	10.01	-96		903	M
9/18/25 18:16	6/13/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Stuglik Brian M	MA	D		9	S.dm	-84	3.73	-23		197	D
9/18/25 18:14	9/16/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Gagnon Robert E.	MA	D		7	S.dm	-11	5.16	-2		42	D
9/18/25 18:11	9/16/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Paterson Dan	MA	DO	P,CEO	15	S.m	-654	6.93	-94		462	D
9/18/25 16:45	7/9/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John	V8	DO	CEO	12	S.dm	-83,651	253.33	-330		54,270	D
9/18/25 16:31	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	15	S.d	-50,506	318.85	-158		37	D
9/18/25 16:06	9/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Looker Benjamin	MI	O	GC	3	S	-26	1.89	-14		401	D
9/18/25 16:06	9/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Koenig Sheldon L.	MI	DO	P,CEO	5	S	-189	1.92	-99		1,572	D
9/18/25 16:06	9/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Halladay Benjamin	MI	O	CFO	8	S	-41	1.96	-21		482	D
9/18/25 16:01	9/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	11	S	-1,617	26.18	-62		228	D
9/17/25 20:08	9/15/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chopas James George	MA	O	VP,Chief	8	S	-130	30.64	-4		54	D
9/17/25 19:39	9/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Tross Stuart A	CT	O	Chief Pe	4	S	-1,317	6.36	-207		1,047	D
9/17/25 18:06	9/16/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Third Rock Ventures Iv, L.P.	MA	T		15	S.m	-41,050	8.49	-4,838		18,651	D
9/17/25 17:01	6/16/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meisner Lara	MA	O	GC	3	S.d	-1,368	12.35	-111	-100	0	D
9/17/25 16:45	9/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	18	S.dm	-16,528	30.14	-548		120	D
9/17/25 16:31	8/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	13	S.d	-27,282	79.94	-341		249	D
9/17/25 16:30	9/15/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Singh Raman	NC	D		2	S.d	-1,396	26.32	-53		31	D
9/17/25 16:15	9/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	7	S	-800	13.45	-60		469	D
9/17/25 16:03	9/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Teresa	CA	O	CHRO	11	S.d	-6,825	40.17	-170		105	D
9/16/25 21:45	12/6/24	OGEN	Oragenics Inc	FL	Health	Drug	Pharmaceutical Preparations	Dunton Alan W	FL	D		2	S.d	-131	13.05	-10		66	D
9/16/25 19:36	9/12/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tabuteau Herriot	NY	DOT	CEO	1	S.dm	-7,362	117.08	-63		7,352	D
9/16/25 18:54	8/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	10	S.d	-2,572	16.60	-155		141	D
9/16/25 18:16	7/29/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	4	S.d	-652	16.93	-38		216	D
9/16/25 18:06	9/12/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hamilton James C	CA	O	Chief Me	4	S.m	-1,674	23.01	-73		272	D
9/16/25 18:00	9/15/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Schneyer Mark C.	CA	O	EVP,CFO	10	S.d	-1,183	20.18	-59		63	D
9/16/25 16:56	9/12/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	8	S.adm	-7,483	57.24	-131		64	D
9/16/25 16:35	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Paulson Richard A.	MA	DO	P,CEO	13	S	-112	2.39	-47		1,150	D
9/16/25 16:34	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mano Michael	MA	O	SVP,GC,S	3	S	-22	3.14	-7		274	D
9/16/25 16:33	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Poulton Stuart	MA	O	EVP,Chie	5	S	-33	2.51	-13		327	D
9/16/25 16:32	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rangwala Reshma	MA	O	EVP,Chie	3	S	-28	6.29	-4		29	D
9/16/25 16:31	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Sohanya Roshan	MA	O	EVP,Chie	3	S	-28	3.03	-9		404	D
9/16/25 16:30	9/3/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Abate Kristin	MA	O	Chief Ac	4	S	-5	5.66	-1		10	D
9/15/25 19:16	9/12/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	17	S	-371	66.16	-6		82	D
9/15/25 18:37	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	11	S.dm	-2,978	17.34	-172		131	D
9/15/25 17:39	9/12/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mottola Frank	MD	O	SVP,Chie	3	S.d	-1,407	41.39	-34		15	D
9/15/25 16:47	9/2/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	30	S.d	-13,291	46.74	-284		443	D
9/15/25 16:26	9/12/25	MRSN	Mersana Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Huber Martin H. Jr.	MA	DO	P,CEO	3	S.d	-106	1.86	-57		123	D
9/15/25 16:23	6/10/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Schaeffer Orlov S Nicole	NJ	O	Chief Pe	14	S.dm	-43,306	88.15	-491		121	D
9/15/25 16:22	9/12/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Sharoky Melvin Md	NJ	D		3	S	-3,965	132.16	-30		334	M
9/15/25 12:45	9/12/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Callicutt Jack W	GA	O	CFO	2	S.d	-92	1.88	-49		8	D
9/15/25 12:45	9/12/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Lewis Joel	GA	DO	P,CEO	2	S.d	-139	1.98	-70		899	D
9/12/25 21:45	9/12/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Todisco Joseph	NJ	O	CEO	1	S.d	-650	13.00	-50		509	D
9/12/25 20:39	9/2/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	20	S.d	-8,542	36.13	-236		313	D
9/12/25 20:39	9/11/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	24	S.dm	-11,919	43.87	-272		96	D
9/12/25 20:38	9/11/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	White William Richard	CA	O	CFO	17	S.dm	-9,233	28.77	-321		62	D
9/12/25 20:36	9/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	18	S.dm	-8,806	49.31	-179		198	D
9/12/25 20:36	9/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	17	S.dm	-21,221	40.00	-530		716	D
9/12/25 20:00	9/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brege Laura	CA	D		2	S.d	-1,580	50.23	-31		31	D
9/12/25 20:00	9/12/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bjerkholt Eric	CA	O	CFO	2	S.d	-728	41.42	-18		40	D
9/12/25 18:00	9/11/25	VTRS	Viatris Inc	DE	Health	Drug	Pharmaceutical Preparations	Le Goff Corinne	PA	O	Chief Co	1	S	-72	10.25	-7		35	D
9/12/25 17:30	9/11/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Hariri Robert J	TN	D		6	S.dm	-405	8.44	-48		51	D
9/12/25 17:09	9/11/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Persky Marla	IL	D		1	S	-120	7.72	-16		148	D
9/12/25 17:09	9/10/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		10	S.dm	-72,927	16.81	-4,339		30,245	I
9/12/25 16:42	9/11/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lonial Sagar	NC	D		3	S.m	-1,257	24.28	-52		105	D
9/12/25 16:38	9/10/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	10	S.d	-8,269	295.91	-28		278	D
9/12/25 16:30	8/7/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	8	S.dm	-6,533	88.71	-74		66	D
9/12/25 16:11	9/12/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parschauer Karah Herdman	CA	O	EVP,GC	5	S.d	-1,354	33.04	-41		107	D
9/12/25 16:07	9/11/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flanagan W. Michael	CA	O	Chief Sc	11	S.d	-12,812	39.64	-323		92	D
9/11/25 21:45	9/9/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zelnick Kaufman Beth	NJ	O	GC	1	S.d	-670	13.41	-50		180	D
9/11/25 21:45	9/9/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hurlburt Elizabeth	NJ	O	COO	2	S.dm	-2,277	11.74	-194		177	D
9/11/25 21:01	9/9/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Robin Howard W	CA	DO	P,CEO	10	S.dm	-1,065	4.29	-248		1,111	D
9/11/25 20:38	9/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		14	S.d	-1,729	60.14	-29	-100	0	D
9/11/25 18:57	9/9/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	Beindorff Michael A	UT	D		2	S	-164	16.10	-10		124	M
9/11/25 17:20	9/9/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Savitz Ryan	NY	O	CFO,CBO	1	S.d	-700	35.00	-20	-100	0	D
9/11/25 17:10	9/9/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Lai	V8	O	Global H	10	S.m	-7,241	263.47	-27		1,797	I
9/11/25 17:05	9/9/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	5	S.d	-2,961	55.49	-53		35	D
9/11/25 16:05	9/9/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Reitan Colleen F	MA	D		2	S.d	-8,425	467.13	-18		1	D
9/10/25 20:12	9/8/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	14	S.dm	-3,073	22.78	-135		394	I
9/10/25 18:21	9/8/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watanabe Todd	CA	DO	See Rema	10	S.dm	-1,653	13.16	-126		1,161	D
9/10/25 17:50	9/8/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ramasastry Saira	CA	D		4	S.dm	-638	15.87	-40		40	D
9/10/25 17:39	9/9/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kooij Louise Frederika	P7	O	Chief Ac	5	S.d	-8,296	22.34	-371		15	D
9/10/25 17:00	9/8/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Elsbernd Brian	FL	O	Chief Co	4	S.dm	-3,330	21.31	-156		271	D
9/10/25 16:31	9/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Malcolm Jan	MD	D		1	S	-280	400.29	-1		1	D
9/10/25 16:30	5/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Thompson Tommy G	MD	D		5	S.d	-6,590	336.91	-20		22	D
9/10/25 16:15	9/8/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gault Cheryl	MA	O	COO	1	S.d	-192	38.33	-5		172	D
9/10/25 16:02	9/8/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sullivan Timothy Eugene	MA	O	CFO	5	S.d	-1,414	28.14	-50		203	M
9/10/25 15:09	9/5/25	CYCC	Cyclacel Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kua Khai Loon	N8	T		1	S	-134	7.01	-19		385	D
9/9/25 21:07	1/24/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sibold William John	PA	DO	P,CEO	4	S	-8,374	366.61	-23		110	D
9/9/25 19:02	9/8/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	15	S.d	-2,046	12.68	-161		395	D
9/9/25 18:37	9/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Schoenberg Mark	NJ	O	Chief Me	7	S.d	-459	14.47	-32		158	D
9/9/25 18:32	9/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Smith Jason Drew	NJ	O	GC	4	S.d	-275	15.33	-18		43	D
9/9/25 18:30	9/5/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	6	S.adm	-3,457	53.29	-65		93	D
9/9/25 17:53	9/5/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Troy Edward	CA	D		4	S.d	-5,879	36.21	-162		756	D
9/9/25 17:31	9/5/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Sanders Corazon (Corsee) D.	V8	D		4	S.d	-1,083	146.58	-7		73	D
9/9/25 16:40	9/5/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Breedlove Robert Charles	NJ	O	Principa	2	S	-20	9.16	-2		55	D
9/9/25 16:31	9/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cox John	MA	DO	CEO,P	3	S	-138	12.79	-11		272	D
9/9/25 16:26	9/5/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Washburn Theodore James Jr.	MA	O	Principa	5	S.d	-556	38.05	-15		9	D
9/8/25 20:32	9/4/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Zalevsky Jonathan	CA	O	Chief R,	9	S.d	-187	1.92	-97		327	D
9/8/25 19:06	9/4/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jung Cassie	NJ	O	COO	2	S.d	-311	5.00	-62		285	D
9/8/25 18:45	9/8/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Metzger Michael A	NY	DO	CEO	4	S.d	-2,976	16.00	-186		300	D
9/8/25 18:06	9/5/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCormick Frank	CA	D		2	S.d	-8,356	48.03	-174		963	D
9/8/25 18:05	9/4/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	12	S.dm	-47,967	37.51	-1,279		6,906	I
9/8/25 17:14	5/28/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Matsuda Masaru	CA	O	See Rema	10	S.d	-1,048	14.03	-75		209	D
9/8/25 17:13	9/5/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Boyd Peter E.	NJ	O	See Rema	1	S	-80	5.30	-15		288	D
9/8/25 16:37	9/4/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Moat Ross	X0	O	CHIEF CO	6	S.dm	-5,634	26.17	-215		22	D
9/8/25 16:37	9/8/25	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Carson Seana	NJ	O	EVP,GC	3	S	-184	6.79	-27		500	D
9/8/25 16:06	9/4/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedl-Naderer Johanna	MA	O	Chief Co	3	S.m	-17	13.17	-1		96	D
9/8/25 16:03	9/4/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kerr Douglas	MA	O	Chief Me	3	S.m	-93	13.03	-7		94	D
9/5/25 19:48	9/5/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Azoy Alexander	CA	O	Chief Ac	3	S	-42	13.44	-3		30	D
9/5/25 19:43	9/5/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saad Mark E	NY	D		2	S.d	-2,147	106.61	-20		10	D
9/5/25 18:56	9/5/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Boyce Sarah	CA	DO	P,CEO	11	S.dm	-23,439	39.21	-598		337	D
9/5/25 18:32	9/3/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mosbrooker Eric	CA	O	Chief Co	2	S.d	-6,073	44.21	-137		55	D
9/5/25 18:00	9/4/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Taubert Jennifer L	NJ	O	EVP,WWC.	1	S.d	-10,041	177.81	-56		178	D
9/5/25 17:01	9/3/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Ramaswamy Vivek	DC	T		4	S.m	-54,126	11.86	-4,565		52,532	D
9/5/25 16:05	9/3/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Cline Christopher R.	CA	O	CFO	8	S.dm	-211	17.71	-12		93	D
9/5/25 16:03	9/4/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fitzpatrick Jennifer	MA	O	GC	1	S.d	-237	23.12	-10	-100	0	D
9/4/25 20:41	9/2/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	6	S.ad	-976	42.70	-23		48	D
9/4/25 20:40	9/2/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Wender Joseph H	CA	D		2	S.m	-3,224	57.58	-56		109	I
9/4/25 20:38	9/9/24	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Parshall B Lynne	CA	D		10	S.d	-3,420	52.62	-65		107	D
9/4/25 20:38	9/3/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	10	S.ad	-17,821	51.28	-348		220	D
9/4/25 20:38	9/3/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Klein Joseph III	CA	D		3	S.d	-3,960	58.24	-68		16	I
9/4/25 20:37	9/2/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Geary Richard S	CA	O	EVP,Chie	7	S.dm	-1,459	43.48	-34		99	D
9/4/25 20:36	9/3/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	2	S.d	-333	44.80	-7		16	D
9/4/25 20:28	9/3/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Loscalzo Joseph	CA	D		2	S.d	-1,474	49.95	-30		36	D
9/4/25 20:28	9/3/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Schneider Eugene	CA	O	EVP,Chf	5	S.ad	-1,970	50.11	-39		61	D
9/4/25 19:59	9/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	17	S.dm	-13,211	57.44	-230		6	D
9/4/25 19:56	9/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	15	S.dm	-23,753	90.10	-264		10	D
9/4/25 19:54	9/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	12	S.dm	-23,656	71.68	-330		118	D
9/4/25 19:54	9/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Belanoff Joseph K	CA	DO	CEO	8	S.dm	-15,501	77.13	-201		3,019	I
9/4/25 18:41	9/2/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		16	S.d	-1,948	12.22	-159		205	D
9/4/25 17:48	2/3/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	Cozadd Bruce C	L2	D		11	S.m	-3,123	127.46	-25		464	D
9/4/25 17:47	9/2/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Kozarich John W	FL	D		3	S	-254	136.03	-2		46	D
9/4/25 17:29	6/11/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Ball Titus B.	V8	O	Principa	3	S	-101	255.74	0		74	D
9/4/25 17:26	9/2/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Smith Michael Alexander	NJ	O	GC	12	S.dm	-18,817	75.11	-251		97	D
9/4/25 17:24	9/2/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Flammer Martina M.D.	NJ	O	Chief Me	16	S.dm	-61,726	88.29	-699		138	D
9/4/25 16:50	9/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Notman Donald	MA	O	See Rema	2	S.m	-149	8.09	-18		309	D
9/4/25 16:44	9/3/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Pera Antonio R	MN	D		2	S	-1,179	92.72	-13		30	D
9/4/25 16:30	9/2/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	12	S.d	-5,239	75.13	-70		9	D
9/4/25 16:30	9/2/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pizzuti Dana	CA	O	Chief Me	9	S.d	-4,190	40.98	-102		96	D
9/4/25 14:58	9/2/25	MTSR	Metsera, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fmr LLC	MA	TH	See Rema	1	S	-10	36.00	0	0	4,325	I
9/4/25 14:54	8/26/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	Yates Bryant J	UT	O	EVP,P,Eu	2	S.m	-209	16.39	-13		99	D
9/3/25 18:53	9/2/25	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burrows Scott L	MA	O	CFO	2	S	-822	22.23	-37		116	D
9/3/25 18:46	9/2/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	Elkins David V	NJ	O	EVP,CFO	1	S	-2,650	47.33	-56		168	D
9/3/25 18:00	9/2/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Garofalo Elizabeth A.	CA	D		2	S	-131	20.13	-7		25	D
9/3/25 17:53	9/2/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticho Barry	MA	O	Chief Me	16	S.dm	-1,846	12.65	-146		61	D
9/3/25 17:51	8/29/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	MA	D		8	S.dm	-2,906	18.27	-159		183	D
9/3/25 17:50	8/29/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Allan Jonathan	MA	O	GC,Corp	7	S.dm	-1,156	15.69	-74		35	D
9/3/25 17:16	8/29/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ridloff Elena	MA	O	CFO,Head	3	S.m	-1,967	23.14	-85		72	D
9/3/25 16:56	8/29/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Smith Thomas B	MA	O	EVP,Chie	2	S	-1,023	37.79	-27		70	D
9/3/25 16:56	9/3/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Megna Michael R	X0	O	CHIEF AC	6	S.dm	-2,239	28.50	-79		38	D
9/3/25 16:33	9/2/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	12	S.d	-2,424	24.30	-100		225	D
9/3/25 16:33	9/2/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	12	S.d	-673	13.84	-49		597	D
9/3/25 16:32	8/29/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Krepp Sarah	NC	O	Chief Hu	2	S	-44	15.35	-3		143	D
9/3/25 16:31	9/2/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	14	S.d	-2,120	17.38	-122		412	D
9/3/25 16:30	8/29/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Boyle Dana	NC	O	Chief Ac	3	S	-46	18.18	-3		187	D
9/3/25 16:20	9/2/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Petersen Floyd F.	CA	D		10	S.d	-390	37.11	-11		81	D
9/3/25 06:04	8/28/25	SPRO	Spero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mahadevia Ankit	MA	D		3	S	-75	0.9170	-82		759	D
9/3/25 06:02	8/28/25	SPRO	Spero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Keutzer Timothy	MA	O	COO	3	S	-50	0.8342	-60		741	D
9/2/25 20:30	9/2/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gallagher Kathleen P.	CA	O	Chief Pr	8	S.dm	-1,221	30.61	-40		51	D
9/2/25 19:46	8/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Manning Paul B	VA	D		1	S.m	-18,957	28.26	-671		5,950	I
9/2/25 19:11	9/2/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NY	D		10	S.dm	-15,117	64.64	-234		2,764	D
9/2/25 17:03	8/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	18	S.dm	-1,029	21.44	-48		194	D
9/2/25 17:02	8/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	12	S.d	-1,081	18.49	-58		273	D
9/2/25 16:34	9/2/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Harrington Robert Arthur	CA	D		5	S	-251	47.12	-5		20	D
9/2/25 16:10	8/29/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Tanguler Tolga	MA	O	EVP,Chie	6	S.d	-3,169	354.91	-9		29	D
8/29/25 20:35	8/27/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szot Matthew K	FL	O	CFO	1	S.m	-28	14.00	-2		31	D
8/29/25 20:34	8/27/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pham Quang X	FL	DOT	CEO,CB	1	S.m	-70	13.99	-5		413	D
8/29/25 17:21	8/28/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Sherman Jeffrey W	IL	D		1	S.d	-335	7.92	-42		225	D
8/29/25 17:03	8/27/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	26	S.dm	-2,126	23.67	-90		23	D
8/29/25 16:19	8/27/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Francois Cedric	MA	DO	CEO	7	S.dm	-10,420	25.25	-413		1,971	I
8/29/25 16:09	8/27/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		3	S.d	-73	40.70	-2		18	D
8/29/25 16:05	11/11/24	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Newhall Charles W III	MD	D		4	S.d	-658	39.39	-17		134	D
8/29/25 16:02	8/27/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	Bhatia Sangeeta N.	MA	D		4	S.d	-1,231	472.60	-3		5	D
8/28/25 19:32	8/26/25	QTTB	Q32 Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	Morrison Jodie Pope	MA	DO	CEO	1	S	-19	1.80	-10		122	D
8/28/25 19:30	8/26/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Williams Laura A	MA	O	Chief Pa	8	S.d	-1,730	6.60	-262		403	D
8/28/25 19:29	8/21/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kelliher Mike	MA	O	Chief Bu	2	S	-91	4.58	-20		282	D
8/28/25 19:28	8/26/25	QTTB	Q32 Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	Violette Shelia M.	MA	O	Chief Sc	1	S	-5	1.80	-3		95	D
8/28/25 19:20	8/26/25	QTTB	Q32 Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kalowski Lee	MA	O	CFO,P	1	S	-8	1.80	-4		49	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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