Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
6/17/25 21:30	6/13/25	VREO	Vireo Growth Inc.	A1	Health	Drug	Pharmaceutical Preparations	Chicago Atlantic Opportunity Portfolio, LP	IL	T		P	2	0.4135	5	0	111,558	I
6/17/25 19:55	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Troy Edward	CA	D		S	-37	3.40	-11	-20	44	D
6/17/25 19:52	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stuglik Brian M	CA	D		S	-27	3.39	-8	-8	95	D
6/17/25 19:49	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Senderowicz Adrian	CA	D		S	-92	3.40	-27	-50	27	D
6/17/25 19:46	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moyes Jay M	CA	D		S	-75	3.40	-22	-29	53	D
6/17/25 19:43	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dorval Allison	CA	D		S	-39	3.40	-12	-13	75	D
6/17/25 19:41	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cesano Alessandra	CA	D		S	-41	3.40	-12	-15	69	D
6/17/25 18:33	6/15/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Jain Rita	CA	D		M.d	0	0.00	7	162	12	D
6/17/25 18:33	6/15/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Fenton Dennis M	CA	D		M.d	0	0.00	6	309	8	D
6/17/25 18:32	6/15/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Marquet Magda	CA	D		M.d	0	0.00	6	155	10	D
6/17/25 18:31	6/15/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Orwin John A	CA	D		M.d	0	0.00	6	181	9	D
6/17/25 18:30	6/15/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Renton Hollings	CA	D		M.d	0	0.00	6	309	8	D
6/17/25 18:30	6/15/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Schmid John P.	CA	D		M.d	0	0.00	6	11	63	D
6/17/25 18:29	6/15/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Ware J. Anthony	CA	D		M.d	0	0.00	6	80	14	D
6/17/25 17:53	6/16/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Duarte IRA	NC	O	EVP,CFO	M.d	0	0.00	13	9	149	D
6/17/25 17:45	6/13/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Heron Patrick J	CA	D		P	35	13.08	3	0	8,863	I
6/17/25 16:44	6/13/25	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Paulson John	FL	D		P	21,171	5.94	3,564	12	32,792	I
6/17/25 16:35	6/13/25	PTN	Palatin Technologies Inc	NJ	Health	Drug	Pharmaceutical Preparations	Wills Stephen T	NJ	O	EVP,CFO,	P.d	225,000	150,000	2	0	1,641	D
6/17/25 16:35	6/13/25	PTN	Palatin Technologies Inc	NJ	Health	Drug	Pharmaceutical Preparations	Spana Carl	NJ	DO	P,CEO	P.d	225,000	150,000	2	0	1,673	D
6/17/25 16:35	6/13/25	PTN	Palatin Technologies Inc	NJ	Health	Drug	Pharmaceutical Preparations	Dunton Alan W	NJ	D		P.d	4,000	20,000	0	0	224	D
6/17/25 16:31	6/16/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	M.d	752	27.85	27	12	249	D
6/17/25 16:31	6/16/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	S.d	-2,077	76.93	-27	-10	249	D
6/17/25 16:27	6/17/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	M.d	21	10.60	2	1	141	D
6/17/25 16:27	6/17/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	S.d	-66	32.91	-2	-1	141	D
6/17/25 16:24	6/13/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	M.d	7	2.48	3	15	23	D
6/17/25 16:24	6/13/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	S.d	-68	22.55	-3	-12	23	D
6/17/25 16:16	6/13/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Capello Jeffrey D	MA	D		M.d	0	0.00	2	100	4	D
6/17/25 16:15	6/13/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Owen Adams Catherine	MA	D		M.d	0	0.00	2	100	4	D
6/17/25 16:11	6/13/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	Lewis Darwin	UT	D		P	5	12.86	0	0	117	D
6/17/25 16:11	6/13/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ogden Christopher	CA	O	CFO	S.dm	-33	2.72	-12	-5	226	D
6/17/25 16:11	6/13/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ogden Christopher	CA	O	CFO	M.d	0	0.00	38	20	226	D
6/17/25 16:10	6/13/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Belvin Marcia	CA	O	SVP,Chie	M.d	0	0.00	38	16	272	D
6/17/25 16:10	6/16/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Belvin Marcia	CA	O	SVP,Chie	S.d	-37	2.69	-14	-5	272	D
6/17/25 16:09	6/13/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Sean A.	CA	DO	CEO	M.d	0	0.00	150	15	1,183	D
6/17/25 16:09	6/16/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Sean A.	CA	DO	CEO	S.d	-149	2.69	-56	-4	1,183	D
6/16/25 21:10	6/13/25	VNDA	Vanda Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mitchell Stephen Ray	DC	D		S	-32	4.59	-7	-7	97	D
6/16/25 20:06	6/12/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ra Capital Management, L.P.	MA	DT		P.m	1,665	10.19	163	1	12,199	I
6/16/25 19:35	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Montgomery Alan Bruce	CA	D		S.d	-20	9.22	-2	-10	21	D
6/16/25 19:31	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Gustafson Kurt A	CA	D		S.d	-28	9.22	-3	-13	20	D
6/16/25 19:30	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Gorman Kevin Charles	CA	D		S.d	-29	9.22	-3	-14	19	D
6/16/25 19:26	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Feigal Ellen	CA	D		S.d	-28	9.22	-3	-13	19	D
6/16/25 19:22	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Ranieri Richard J	CA	D		S.d	-28	9.22	-3	-13	19	D
6/16/25 19:05	6/12/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaplan Gilla	CA	D		S.m	-535	10.32	-52	-58	38	D
6/16/25 19:03	6/14/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Steinhart Richard I	CT	O	CFO	M.dm	0	0.00	0	5	1	D
6/16/25 19:02	6/14/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yocca Frank	CT	O	Chief Sc	M.dm	0	0.00	0	4	2	D
6/16/25 19:01	6/14/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mehta Vimal	CT	DO	CEO,P	M.dm	0	0.00	0	0	485	D
6/16/25 19:00	6/14/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodriguez Javier	CT	O	See Rema	M.dm	0	0.00	0	4	2	D
6/16/25 18:05	6/13/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gengos Andrew	CA	O	CFO	P.m	57	3.81	15	New	15	D
6/16/25 17:47	6/13/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Echelard Yann	NC	D		S	-369	36.94	-10	-4	229	D
6/16/25 17:24	6/13/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	S	-25	61.37	0	-1	79	D
6/16/25 17:19	6/16/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	S	-169	33.80	-5	-1	407	D
6/16/25 17:19	6/13/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Zhang Jack Y.	CA	DOT	CEO,Chie	M.d	2,606	13.03	200	2	10,861	D
6/16/25 17:00	6/13/25	IMUX	Immunic, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nash Duane	NY	DO	Exec CB	P	17	0.8347	20	125	36	D
6/16/25 17:00	6/12/25	VREO	Vireo Growth Inc.	A1	Health	Drug	Pharmaceutical Preparations	Chicago Atlantic Opportunity Portfolio, LP	IL	T		P	29	0.4157	70	0	111,553	I
6/16/25 16:56	6/12/25	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Krempa David	IL	O	Chief Bu	S.m	-504	14.83	-34	-5	613	D
6/16/25 16:48	6/12/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Betz Stephen F.	CA	O	Chief Sc	M.d	291	3.30	88	764	100	D
6/16/25 16:48	6/12/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Betz Stephen F.	CA	O	Chief Sc	S.d	-3,142	32.23	-97	-49	100	D
6/16/25 16:42	6/13/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moatazedi David	CA	DO	See Rema	S.m	-1,283	10.03	-128	-26	365	D
6/16/25 16:26	6/13/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	McCulloch Kevin	IL	O	See Rema	P	109	4.38	25	1	1,736	D
6/16/25 16:03	6/12/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Kalif Eliyahu Sharon	L3	O	EVP,CFO	S	-952	17.08	-56	-12	403	D
6/16/25 16:03	6/12/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	M.d	7	1.08	6	7	102	D
6/16/25 16:03	6/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	S.d	-166	14.60	-11	-10	102	D
6/16/25 15:40	5/28/25	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leonard Braden Michael	IN	T		S	-218	1.09	-200	-6	3,017	I
6/16/25 10:22	6/13/25	ACUT	Accustem Sciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cerrone Gabriele M	NY	DT		P	2	1.02	2	0	6,502	I
6/16/25 08:48	6/12/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	M.d	1,490	135.42	11	43	37	D
6/16/25 08:48	6/12/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	S.d	-3,080	279.96	-11	-23	37	D
6/13/25 20:00	6/13/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Verdine Gregory L.	MA	D		S	-209	6.95	-30	-10	283	D
6/13/25 19:57	6/13/25	LTRN	Lantern Pharma Inc.	TX	Health	Drug	Pharmaceutical Preparations	Fletcher Aaron G.L.	TX	T		S	-124	3.09	-40	-4	1,076	I
6/13/25 19:50	6/13/25	LTRN	Lantern Pharma Inc.	TX	Health	Drug	Pharmaceutical Preparations	Kreis Leslie W.	TX	T		S	-124	3.09	-40	-4	1,076	I
6/13/25 19:38	6/12/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	S	-3	10.00	0	0	102	D
6/13/25 19:00	6/11/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Mandalam Ramkumar	TN	D		S.m	-75	7.03	-11	-14	66	D
6/13/25 17:05	6/11/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Roberts Eric W	CA	DOT	CHIEF BU	P	9	1.85	5	1	993	I
6/13/25 16:31	6/11/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Hahn Mark W	X0	O	CFO	S	-4,560	11.40	-400	-3	12,279	D
6/13/25 16:30	6/11/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Zaccardelli David	X0	DO	P,CEO	S	-4,561	11.40	-400	-3	13,190	D
6/13/25 16:18	6/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fairey William	CA	D		S	-155	48.42	-3	-56	3	D
6/13/25 10:26	6/11/25	ACUT	Accustem Sciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cerrone Gabriele M	NY	DT		P.m	18	0.4964	37	1	6,500	I
6/13/25 08:00	6/12/25	SLS	Sellas Life Sciences Group, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Van Nostrand Robert L	NY	D		P	15	1.48	10	96	20	D
6/13/25 06:06	6/10/25	LTRN	Lantern Pharma Inc.	TX	Health	Drug	Pharmaceutical Preparations	Fletcher Aaron G.L.	TX	T		S.m	-208	3.38	-62	-5	1,116	I
6/13/25 06:01	6/10/25	LTRN	Lantern Pharma Inc.	TX	Health	Drug	Pharmaceutical Preparations	Kreis Leslie W.	TX	T		S.m	-208	3.38	-62	-5	1,116	I
6/12/25 20:42	6/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		M.d	31	14.08	2		0	D
6/12/25 20:42	6/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		S.d	-155	70.61	-2	-100	0	D
6/12/25 20:41	6/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	M.d	433	21.65	20		5	D
6/12/25 20:41	6/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	S.d	-1,448	72.42	-20	-78	5	D
6/12/25 20:17	6/10/25	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Paulson John	FL	D		P.m	14,700	5.27	2,789	11	29,228	I
6/12/25 18:34	6/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	S	-2,045	54.05	-38	-6	556	D
6/12/25 18:33	6/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	S	-127	54.00	-2	-1	167	D
6/12/25 18:33	6/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	White William Richard	CA	O	CFO	S	-151	54.00	-3	-5	59	D
6/12/25 18:33	6/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	S	-151	54.00	-3	-3	92	D
6/12/25 18:32	6/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lamy Patrick	CA	O	SVP,Comm	S	-50	54.00	-1	-3	33	D
6/12/25 18:32	6/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	S	-135	53.99	-2	-1	258	D
6/12/25 18:18	6/11/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flanagan W. Michael	CA	O	Chief Sc	M.d	284	14.22	20	33	80	D
6/12/25 18:18	6/11/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flanagan W. Michael	CA	O	Chief Sc	S.d	-658	32.88	-20	-20	80	D
6/12/25 17:51	6/10/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Reardon Andrew	FL	O	CLO,Secr	S	-57	114.54	-1	-2	32	D
6/12/25 17:51	6/11/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Ball Titus B.	V8	O	Principa	S	-35	258.36	0	0	74	D
6/12/25 17:39	6/10/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Xiaodong	V8	DH	Chair, S	M.d	271	6.50	42	0	10,159	D
6/12/25 17:39	6/10/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Xiaodong	V8	DH	Chair, S	S.d	-10,975	262.82	-42	0	10,159	D
6/12/25 17:00	6/10/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sundaram Preethi	FL	O	Chief St	S.m	-104	26.41	-4	-9	41	D
6/12/25 16:50	6/10/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	German Christopher Paul	MA	O	Corporat	M.d	19	17.97	1	130	2	D
6/12/25 16:50	6/10/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	German Christopher Paul	MA	O	Corporat	S.d	-139	67.19	-2	-52	2	D
6/12/25 16:32	6/10/25	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		P	125	15.82	8	0	2,855	I
6/12/25 16:21	6/10/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Flammer Martina M.D.	NJ	O	Chief Me	M.dm	1,013	22.42	45	119	83	D
6/12/25 16:21	6/10/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Flammer Martina M.D.	NJ	O	Chief Me	S.dm	-4,117	91.16	-45	-35	83	D
6/12/25 16:20	6/10/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Schaeffer Orlov S Nicole	NJ	O	Chief Pe	M.dm	1,631	15.06	108		89	D
6/12/25 16:20	6/10/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Schaeffer Orlov S Nicole	NJ	O	Chief Pe	S.dm	-12,659	92.09	-137	-61	89	D
6/12/25 16:19	6/10/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Patel Gautam	NJ	D		S	-453	8.02	-56	-3	1,704	D
6/12/25 16:19	6/10/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	M.d	863	18.02	48	86	103	D
6/12/25 16:19	6/10/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	S.d	-5,148	89.12	-58	-36	103	D
6/11/25 21:40	6/9/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mott David M	MA	D		P	737	3.69	200	8	2,697	D
6/11/25 20:34	6/9/25	ERNA	Ernexa Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cherington Charles	MA	T		P	2,222	0.1046	21,241	104	41,660	D
6/11/25 19:44	6/9/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ra Capital Management, L.P.	MA	DT		P	1,904	10.19	187	2	12,035	I
6/11/25 18:37	6/10/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	S.m	-33	10.01	-3	-3	102	D
6/11/25 18:25	6/6/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Czirr James C	WA	T		M.d	699	2.16	323	45	1,046	D
6/11/25 18:25	6/9/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	S	-136	20.34	-7	-2	303	I
6/11/25 18:14	6/10/25	VREO	Vireo Growth Inc.	A1	Health	Drug	Pharmaceutical Preparations	Chicago Atlantic Opportunity Portfolio, LP	IL	T		P.m	68	0.4009	170	0	111,483	I
6/11/25 17:40	6/9/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Molina Arturo Md	CA	O	Chief Me	M.dm	161	8.04	20	31	84	D
6/11/25 17:40	6/9/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Molina Arturo Md	CA	O	Chief Me	S.dm	-1,125	56.27	-20	-19	84	D
6/11/25 17:35	6/9/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Quart Barry D	X0	D		M.dm	104	3.80	27		13	D
6/11/25 17:35	6/9/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Quart Barry D	X0	D		S.dm	-833	30.35	-27	-69	13	D
6/11/25 17:32	6/9/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	M.dm	734	10.36	71	999%	72	D
6/11/25 17:32	6/9/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	S.dm	-2,160	30.48	-71	-49	72	D
6/11/25 17:13	6/9/25	AKBA	Akebia Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Malabre Richard C	MA	O	SVP,Chie	M.d	25	1.68	15	6	267	D
6/11/25 17:13	6/9/25	AKBA	Akebia Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Malabre Richard C	MA	O	SVP,Chie	S.d	-60	4.01	-15	-5	267	D
6/11/25 17:04	6/9/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Freund John Gordon	MA	D		M.d	202	13.45	15	15	114	D
6/11/25 17:04	6/9/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Freund John Gordon	MA	D		S.d	-202	30.62	-7	-5	114	D
6/11/25 17:00	6/9/25	VRDN	Viridian Therapeutics, Inc.De	DE	Health	Drug	Pharmaceutical Preparations	Fairmount Funds Management LLC	PA	DT		M.dm	166	11.80	14	0	3,460	I
6/11/25 17:00	6/10/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Valantine Hannah	CA	D		M.d	72	16.75	4	474	5	D
6/11/25 17:00	6/10/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Valantine Hannah	CA	D		S.d	-172	40.00	-4	-45	5	D
6/11/25 17:00	6/10/25	PHIO	Phio Pharmaceuticals Corp.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Robert J	MA	DO	CB,P,CEO	P	5	2.42	2	8	27	D
6/11/25 16:59	6/10/25	PHIO	Phio Pharmaceuticals Corp.	DE	Health	Drug	Pharmaceutical Preparations	Ferrara Robert L	MA	D		P	6	2.42	3	19	16	D
6/11/25 16:33	6/10/25	SIGA	Siga Technologies Inc	DE	Health	Drug	Pharmaceutical Preparations	Ford Harold Eugene Jr.	NY	D		M.d	0	0.00	19	165	31	D
6/11/25 16:33	6/10/25	SIGA	Siga Technologies Inc	DE	Health	Drug	Pharmaceutical Preparations	Nemirovsky Julian	NY	D		M.d	0	0.00	19	51	57	D
6/11/25 16:32	6/10/25	SIGA	Siga Technologies Inc	DE	Health	Drug	Pharmaceutical Preparations	Phillips Holly L.	NY	D		M.d	0	0.00	19	51	57	D
6/11/25 16:32	6/10/25	SIGA	Siga Technologies Inc	DE	Health	Drug	Pharmaceutical Preparations	Marshall Joseph W III	NY	D		M.d	0	0.00	19	9	230	D
6/11/25 16:31	6/10/25	SIGA	Siga Technologies Inc	DE	Health	Drug	Pharmaceutical Preparations	Durnan Jaymie A	NY	D		M.d	0	0.00	19	36	72	D
6/11/25 16:29	6/10/25	SIGA	Siga Technologies Inc	DE	Health	Drug	Pharmaceutical Preparations	Nabel Gary J.	NY	D		M.d	0	0.00	19	51	57	D
6/11/25 16:15	6/9/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		S.m	-924	30.59	-30	-1	3,905	I
6/11/25 09:14	6/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Schoenberg Mark	NJ	O	Chief Me	M.d	0	0.00	10	7	153	D
6/11/25 09:14	6/9/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Schoenberg Mark	NJ	O	Chief Me	S.d	-38	7.37	-5	-3	153	D
6/10/25 20:07	6/10/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Binder Steven B.	CT	D		S	-256	4.00	-64	-6	925	D
6/10/25 19:28	6/10/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Zecchini Edward J	TN	O	Chief Di	M.d	230	3.07	75	487	90	D
6/10/25 19:28	6/10/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Zecchini Edward J	TN	O	Chief Di	S.d	-353	6.85	-52	-36	90	D
6/10/25 19:25	6/9/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Mandalam Ramkumar	TN	D		S.d	-40	7.06	-6	-7	77	D
6/10/25 19:00	6/9/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jacobson Mark L.	NY	O	COO	M.d	201	8.02	25		6	D
6/10/25 19:00	6/9/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jacobson Mark L.	NY	O	COO	S.d	-2,761	110.44	-25	-81	6	D
6/10/25 17:26	6/9/25	CNTX	Context Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lehr Martin A.	PA	DO	CEO	P	70	0.7008	100	10	1,080	I
6/10/25 17:25	6/4/25	ASBP	Aspire Biopharma Holdings, Inc.	E9	Health	Drug	Pharmaceutical Preparations	Fell Donald G.	PR	D		P.am	8	0.3900	20	New	20	D
6/10/25 17:23	6/6/25	CNTX	Context Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levit Alex C.	PA	O	GC,Corp.	P	12	0.5760	20	32	82	D
6/10/25 17:22	6/6/25	CNTX	Context Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Minai-Azary Jennifer Lynn	PA	O	CFO	P	25	0.6370	40	100	80	D
6/10/25 17:04	6/9/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	White Albert G III	CA	D		P	189	9.45	20	66	50	D
6/10/25 17:00	6/6/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	M.d	0	0.00	16	5	315	D
6/10/25 17:00	6/9/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	S.d	-104	14.50	-7	-2	315	D
6/10/25 17:00	6/6/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McEnany Patrick J	FL	DH	Chairman	S.m	-5,217	26.09	-200	-4	4,282	D
6/10/25 16:57	6/6/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	S	-179	256.11	-1	0	237	D
6/10/25 16:56	6/6/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Lai	V8	O	Global H	S	-354	252.39	-1	0	1,704	D
6/10/25 16:55	6/6/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wu Xiaobin	V8	O	P,COO	S	-490	253.15	-2	0	1,167	D
6/10/25 16:54	6/6/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John	V8	DO	CEO	S	-1,296	252.77	-5	0	54,152	D
6/10/25 16:45	6/6/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	M.d	48	6.80	7	58	19	D
6/10/25 16:45	6/6/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	S.d	-478	68.05	-7	-27	19	D
6/10/25 16:43	6/9/25	PHIO	Phio Pharmaceuticals Corp.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Robert J	MA	DO	CB,P,CEO	P	4	2.75	2	6	25	D
6/10/25 16:39	6/9/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Nichols Christian Todd	MA	O	SVP,Chie	S.m	-210	31.52	-7	-7	86	D
6/10/25 16:38	6/6/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	M.d	6	28.59	0	0	63	D
6/10/25 16:38	6/6/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	S.d	-16	79.82	0	0	63	D
6/10/25 16:37	6/8/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Wright Christopher I		D		M.d	0	0.00	3	17	23	D
6/10/25 16:30	6/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Edgemond James	MD	O	CFO,TREA	M.d	1,413	117.76	12		8	D
6/10/25 16:30	6/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Edgemond James	MD	O	CFO,TREA	S.d	-3,904	325.38	-12	-60	8	D
6/10/25 16:05	6/6/25	VREO	Vireo Growth Inc.	A1	Health	Drug	Pharmaceutical Preparations	Chicago Atlantic Opportunity Portfolio, LP	IL	T		P.m	35	0.4065	87	0	111,313	I
6/10/25 15:06	6/9/25	AYTU	Aytu Biopharma, Inc	DE	Health	Drug	Pharmaceutical Preparations	Disbrow Jarrett	CO	O	Chief Bu	P	25	1.50	17	130	29	D
6/10/25 15:04	6/9/25	AYTU	Aytu Biopharma, Inc	DE	Health	Drug	Pharmaceutical Preparations	Disbrow Joshua R.	CO	O	CEO	P	100	1.50	67	77	153	D
6/10/25 11:22	6/6/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	Bezerra Eduardo Guarita	MI	O	EVP,CFO	M.d	119	26.16	5	11	46	D
6/10/25 11:22	6/6/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	Khoury Roberto	MI	O	EVP,P of	M.d	284	26.16	11		5	D
6/9/25 20:49	6/6/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Savage William Jacob	MA	O	Chief Me	S	-150	50.00	-3	-5	57	D
6/9/25 20:18	6/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	S.m	-29	10.01	-3	-3	104	D
6/9/25 19:54	6/6/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Forbes William P	NC	O	EVP,Chie	M.d	0	0.00	13	10	135	D
6/9/25 17:30	6/5/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	M.dm	791	21.09	38	28	170	D
6/9/25 17:30	6/5/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	S.dm	-2,045	54.52	-38	-18	170	D
6/9/25 17:19	6/5/25	RFL	Rafael Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jonas Howard S	NJ	DOT	Exec CB,	P	16,743	1.28	13,080	813	14,689	I
6/9/25 16:25	6/6/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Vergis Janet S.	L3	D		M.d	0	0.00	10	15	74	D
6/9/25 16:22	6/6/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Zaks Tal Zvi	L3	D		M.d	0	0.00	10	20	59	D
6/9/25 16:20	6/6/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Shalev Varda	L3	D		M.d	0	0.00	10	75	23	D
6/9/25 16:20	6/6/25	ACRS	Aclaris Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schiff Andrew N	PA	D		M.d	0	0.00	5	1	448	D
6/9/25 16:20	6/6/25	ACRS	Aclaris Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Milano Vincent	PA	D		M.d	0	0.00	5	38	17	D
6/9/25 16:20	6/6/25	ACRS	Aclaris Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mehra Anand	PA	D		M.d	0	0.00	5	1	715	D
6/9/25 16:20	6/6/25	ACRS	Aclaris Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Humphries William D.	PA	D		M.d	0	0.00	5	17	34	D
6/9/25 16:20	6/6/25	ACRS	Aclaris Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gowen Maxine	PA	D		M.d	0	0.00	5	28	22	D
6/9/25 16:20	6/6/25	ACRS	Aclaris Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Molineaux Christopher P.	PA	D		M.d	0	0.00	5	9	58	D
6/9/25 16:18	6/6/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Satchi-Fainaro Ronit	L3	D		M.d	0	0.00	10	11	98	D
6/9/25 16:15	6/6/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Nisen Perry	L3	D		M.d	0	0.00	10	10	105	D
6/9/25 16:13	6/6/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Lieberman Gerald M	L3	D		M.d	0	0.00	10	9	116	D
6/9/25 16:11	6/6/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Elstein Amir	L3	D		M.d	0	0.00	10	0	2,104	D
6/9/25 16:09	6/6/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Crane Rosemary A	L3	D		M.d	0	0.00	10	9	113	D
6/9/25 16:08	6/5/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Roberts Eric W	CA	DOT	CHIEF BU	P.m	18	1.74	10	1	988	I
6/9/25 16:07	6/5/25	IMUX	Immunic, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tardio Jason	NY	O	P,COO	P.d	10	0.7900	13	New	13	D
6/9/25 16:05	6/6/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Barer Sol J	L3	D		M.d	0	0.00	17	4	426	D
6/9/25 16:03	6/6/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Mignone Roberto	L3	D		M.d	0	0.00	10	1	800	D
6/9/25 06:03	6/5/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Agah Ramtin	CA	DO	Chief Me	P	29	1.40	21	3	734	D
6/6/25 18:05	6/4/25	VREO	Vireo Growth Inc.	A1	Health	Drug	Pharmaceutical Preparations	Chicago Atlantic Opportunity Portfolio, LP	IL	T		P.m	11	0.4050	26	0	111,227	I
6/6/25 18:04	6/6/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vazzano Joseph Walter	OH	O	CFO	S	-120	6.76	-18	-3	491	D
6/6/25 18:00	6/6/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seshadri Vishwas	OH	DO	CEO	S	-343	6.76	-51	-4	1,304	D
6/6/25 17:58	6/5/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	Gannon Steven	A1	D		S.d	0	30.48	0	0	7	D
6/6/25 17:56	6/6/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	O'Malley Brendan M.	OH	O	SVP,GC	S	-71	6.76	-10	-3	378	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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