Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
5/29/26 21:02	5/27/26	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Thompson Peter A.	MA	D		S	-4	44.49	0	0	2,672	I
5/29/26 20:57	5/27/26	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S	-4	44.49	0	0	2,672	I
5/29/26 18:51	5/27/26	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Evnin Luke	MA	D		S.m	-66	0.4692	-141	-18	623	I
5/29/26 18:28	5/28/26	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tom Penny	CA	O	Principa	S.d	-192	2.95	-65	-100	0	D
5/29/26 18:19	5/27/26	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zedelmayer Christine	CA	O	SVP,COO	S.dm	-267	2.79	-96	-60	63	D
5/29/26 18:11	5/27/26	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	S	-325	65.00	-5	-45	6	D
5/29/26 18:03	5/27/26	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	S.d	-4,919	65.59	-75	-39	119	D
5/29/26 18:03	5/29/26	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Parisi Samuel Joseph	MA	O	VP,Finan	S.d	-687	42.36	-16	-68	8	D
5/29/26 16:37	5/28/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Edgemond James	MD	O	CFO,TREA	S.d	-5,656	565.63	-10	-35	19	D
5/29/26 16:37	5/28/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-5,374	565.64	-10	-1	669	D
5/29/26 16:30	5/11/26	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pham Quang X	FL	DOT	CEO,CB	S.m	-69	5.44	-13	-3	382	D
5/29/26 16:16	5/28/26	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brynjelsen Sean	IL	DO	P,CEO	S	-3,826	31.88	-120	-13	834	D
5/29/26 16:05	5/27/26	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yea Christopher	MA	O	CHIEF DE	S.d	-905	26.78	-34	-13	230	D
5/28/26 19:02	5/26/26	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shaikhly Samira	CA	O	Chief Pe	S.d	-355	30.06	-12	-94	1	D
5/28/26 16:48	5/26/26	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Coyne Terrance P.	NY	O	EVP,CFO	S	-3,476	53.98	-64	-56	50	I
5/28/26 16:33	5/27/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-5,466	575.40	-10	-1	669	D
5/28/26 16:30	5/27/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	S	-400	62.18	-6	0	2,226	I
5/28/26 16:21	5/27/26	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	S	-579	77.21	-8	-2	397	D
5/28/26 16:19	5/26/26	RIGL	Rigel Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Ali-Jackson Kamil	CA	D		S	-73	29.17	-3	-17	13	D
5/28/26 16:15	5/26/26	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Third Rock Ventures V, L.P.	MA	T		S	-744	40.05	-19	0	7,250	D
5/28/26 16:08	5/26/26	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Dugel Pravin	MA	DO	See Rema	S	-173	8.20	-21	-1	3,292	M
5/28/26 16:07	5/26/26	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Kaiser Peter	MA	O	Chief De	S	-24	8.20	-3	-1	266	D
5/28/26 16:06	5/26/26	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Heier Jeffrey S.	MA	O	Chief Sc	S	-25	8.20	-3	-1	320	D
5/28/26 16:05	5/26/26	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Nayak Sanjay	MA	O	Chief St	S	-15	8.20	-2	-1	329	D
5/28/26 09:13	5/26/26	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Jamil Khurram	GA	O	Chief Me	S.d	-2	3.10	-1	-100	0	D
5/27/26 18:35	5/22/26	CNTN	Canton Strategic Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stetz Gary S.	NJ	D		S.m	-344	3.43	-100	-43	134	D
5/27/26 18:28	5/22/26	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Krempa David	IL	O	Chief Bu	S.dm	-3,230	32.30	-100	-80	25	D
5/27/26 18:21	5/22/26	OMER	Omeros Corp	WA	Health	Drug	Pharmaceutical Preparations	Cable Thomas J.	WA	D		S.d	-87	11.61	-8	-18	35	D
5/27/26 18:13	5/22/26	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	Winningham Rick E		D		S.d	-662	241.57	-3	-22	10	D
5/27/26 18:07	5/22/26	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	McSharry Heather Ann		D		S	-482	241.00	-2	-10	18	D
5/27/26 18:00	5/26/26	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Kihara James	CA	O	PRINCIPA	S	-114	21.18	-5	-18	25	D
5/27/26 17:29	5/22/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Riva Alessandro		D		S	-66	309.51	0	0	54	D
5/27/26 17:26	5/22/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Dugan Margaret		D		S	-66	309.60	0	0	54	D
5/27/26 17:26	5/22/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Sanders Corazon (Corsee) D.		D		S	-66	309.59	0	0	54	D
5/27/26 16:54	5/22/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	D		S	-262	23.82	-11	0	8,962	I
5/27/26 16:31	5/26/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Edgemond James	MD	O	CFO,TREA	S.d	-5,729	572.94	-10	-35	19	D
5/27/26 16:30	5/26/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-4,579	572.38	-8	-1	669	D
5/27/26 16:30	5/26/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kooij Louise Frederika		O	Chief Ac	S.d	-2,320	35.69	-65	-73	24	D
5/27/26 16:05	5/26/26	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yea Christopher	MA	O	CHIEF DE	S.d	-53	26.78	-2	-1	230	D
5/27/26 16:05	5/26/26	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sweeny Nicole	MA	O	Chief Co	S.d	-40	26.78	-1	-2	59	D
5/27/26 16:05	5/26/26	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Audhya Paul K.	MA	O	CHIEF ME	S.d	-60	26.78	-2	-1	150	D
5/27/26 16:01	5/22/26	GYRE	Gyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ye Weiguo	CA	O	COO	S.dm	-46	6.09	-8	-1	700	D
5/26/26 21:06	5/22/26	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pham Quang X	FL	DOT	CEO,CB	S	-7	5.69	-1	-1	215	D
5/26/26 19:47	5/21/26	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shah Gaurav	NJ	O	CEO	S.d	-172	3.09	-56	-4	1,468	D
5/26/26 19:35	5/22/26	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	S.d	-293	26.78	-11	-2	480	D
5/26/26 19:34	5/22/26	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sweeny Nicole	MA	O	Chief Co	S.d	-50	26.78	-2	-3	56	D
5/26/26 19:33	5/22/26	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yea Christopher	MA	O	CHIEF DE	S.d	-63	26.78	-2	-1	229	D
5/26/26 19:33	5/22/26	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Audhya Paul K.	MA	O	CHIEF ME	S.d	-72	26.78	-3	-2	147	D
5/26/26 19:32	5/22/26	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piekos Brian	MA	O	CFO	S.d	-40	26.78	-1	-6	22	D
5/26/26 18:18	5/21/26	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Evnin Luke	MA	D		S.m	-87	0.4514	-192	-20	764	I
5/26/26 18:17	5/21/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Singh Raman	NC	D		S.d	-1,773	60.13	-29	-43	39	D
5/26/26 18:16	5/21/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	S.m	-4,576	61.01	-75	-3	2,232	I
5/26/26 17:53	5/21/26	PHVS	Pharvaris N.V.	P7	Health	Drug	Pharmaceutical Preparations	Monges Viviane	MA	D		S	-293	30.29	-10	-64	6	D
5/26/26 17:48	5/21/26	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	S.d	-188	20.42	-9	-6	145	D
5/26/26 17:45	5/21/26	PHVS	Pharvaris N.V.	P7	Health	Drug	Pharmaceutical Preparations	Nijdam Anna	MA	O	Principa	S.dm	-225	30.70	-7	-13	49	D
5/26/26 17:42	5/21/26	PHVS	Pharvaris N.V.	P7	Health	Drug	Pharmaceutical Preparations	Nassif David W.	MA	O	CFO , CL	S	-303	30.31	-10	-8	120	D
5/26/26 16:54	5/21/26	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	S	-1,813	69.44	-26	-1	5,157	D
5/26/26 16:44	5/22/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-5,394	567.74	-10	-1	680	D
5/26/26 16:43	5/21/26	PEPG	Pepgen Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kasraian Kasra	MA	O	Chief Te	S	-2	1.41	-1	-2	50	D
5/22/26 19:02	5/20/26	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yocca Frank	CT	O	Chief Sc	S.d	-7	1.09	-7	-21	26	D
5/22/26 19:02	5/20/26	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodriguez Javier	CT	O	See Rema	S.d	-7	1.08	-7	-20	27	D
5/22/26 19:01	5/20/26	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Steinhart Richard I	CT	O	CFO	S.d	-7	1.09	-7	-21	26	D
5/22/26 19:00	5/20/26	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mehta Vimal	CT	DO	CEO,P	S.d	-21	1.09	-19	-3	550	D
5/22/26 18:25	5/22/26	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric		O	P,Immuno	S.d	-6,054	30.27	-200	-11	1,613	D
5/22/26 18:19	5/20/26	GYRE	Gyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ye Weiguo	CA	O	COO	S.dm	-137	6.15	-22	-3	700	D
5/22/26 18:01	5/22/26	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levy Richard S	PA	D		S	-2,929	515.44	-6	-21	22	D
5/22/26 17:24	5/22/26	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Alvino Mark	OH	D		S	-35	5.46	-7	-8	78	D
5/22/26 17:16	5/21/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Edgemond James	MD	O	CFO,TREA	S.d	-5,641	564.11	-10	-35	19	D
5/22/26 16:54	5/21/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dambkowski Carl	CA	D		S.d	-6,191	58.97	-105	-59	74	D
5/22/26 16:46	5/21/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-5,359	564.11	-10	-1	680	D
5/22/26 16:25	5/22/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Smith Michael Alexander	NJ	O	GC	S	-667	108.47	-6	-13	42	D
5/22/26 16:18	5/21/26	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Reilly Joseph James	MA	O	See Rema	S	-23	6.27	-4	-2	150	D
5/22/26 16:17	5/21/26	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohenleitner Susan	MA	O	CFO	S	-9	6.27	-1	-1	229	D
5/22/26 16:15	5/21/26	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bishop John E	MA	O	See Rema	S	-14	6.27	-2	-1	337	D
5/22/26 16:15	5/21/26	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Teel Randy	CT	DO	P,CEO	S	-20	9.04	-2	-1	285	D
5/22/26 16:14	5/21/26	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brady James Parker	MA	O	CHRO	S	-12	6.27	-2	-1	261	D
5/22/26 16:12	5/21/26	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Foster Eric Duane	MA	O	Chief Co	S	-50	6.27	-8	-2	418	D
5/22/26 16:10	5/21/26	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kelliher Mike	MA	O	Chief Bu	S	-45	6.27	-7	-2	357	D
5/22/26 16:09	5/21/26	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Williams Laura A	MA	O	Chief Pa	S	-44	6.27	-7	-2	429	D
5/22/26 16:06	5/21/26	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Raab Michael	MA	DO	P,CEO	S	-343	6.27	-55	-3	1,745	D
5/22/26 16:05	5/20/26	AZN	Astrazeneca Plc	X0	Health	Drug	Pharmaceutical Preparations	Sharma Mani		O	See Rema	S	-2,209	185.78	-12	-38	19	D
5/22/26 16:05	5/20/26	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Goin Kathleen	PA	O	COO	S.d	-476	110.56	-4	-100	0	D
5/22/26 16:05	5/21/26	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Powl Brian T.	CA	O	Chief Co	S	-110	11.00	-10	-5	174	D
5/22/26 14:54	5/20/26	PHVS	Pharvaris N.V.	P7	Health	Drug	Pharmaceutical Preparations	Bjork Elisabeth	MA	D		S.d	-293	29.32	-10	-40	15	D
5/22/26 11:59	5/21/26	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	Brower Nathan G	UT	O	EVP,GC	S	-262	21.84	-12	-22	43	D
5/21/26 21:20	5/20/26	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Urist Marshall	NY	O	EVP,Rese	S	-722	52.75	-14	-27	37	D
5/21/26 18:26	5/19/26	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Zalevsky Jonathan	CA	O	Chief R,	S	-13	65.51	0	-1	21	D
5/21/26 18:26	5/19/26	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Robin Howard W	CA	DO	P,CEO	S	-29	65.51	0	-1	75	D
5/21/26 16:34	5/20/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-5,377	565.98	-10	-1	680	D
5/21/26 16:33	5/21/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	S.d	-4,671	562.82	-8	-16	45	D
5/21/26 16:06	5/19/26	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shah Gaurav	NJ	O	CEO	S	-7	3.01	-2	0	1,447	D
5/21/26 16:06	5/19/26	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Martin	NJ	O	GC	S	-2	3.01	-1	0	678	D
5/21/26 16:06	5/19/26	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Militello John	NJ	O	See Rema	S	-1	3.01	0	0	90	D
5/21/26 12:08	5/13/26	ANL	Adlai Nortye Ltd.	DE	Health	Drug	Pharmaceutical Preparations	Lu Yang		DOT	CEO	S	0	13.18	0	0	100	D
5/20/26 20:51	5/19/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Caligan Partners LP	NY	DTH	See Rema	S	-318	59.98	-5	0	16,291	I
5/20/26 19:29	5/18/26	IRD	Opus Genetics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Foundation Fighting Blindness Retinal Degeneration Fund	NC	DH	See Rema	S	-7,395	4.35	-1,700	-31	3,792	D
5/20/26 18:55	5/18/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	S.m	-4,418	58.91	-75	-3	2,307	I
5/20/26 18:08	5/18/26	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Evnin Luke	MA	D		S.m	-76	0.4464	-171	-15	955	I
5/20/26 17:41	5/19/26	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Lee Frank D.	NJ	D		S	-133	5.43	-24	-33	49	D
5/20/26 17:33	5/18/26	PHVS	Pharvaris N.V.	P7	Health	Drug	Pharmaceutical Preparations	Modig Berndt	MA	DO	CEO	S	-67	29.22	-2	-2	138	D
5/20/26 16:34	5/19/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-5,395	567.94	-10	-1	680	D
5/20/26 16:18	5/18/26	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Collins Helen Louise	CO	O	Chief Me	S.d	-199	39.79	-5	-17	25	D
5/20/26 16:07	5/18/26	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazumdar Claire	MA	DO	CEO	S.d	-301	20.04	-15	-4	362	D
5/20/26 16:06	5/18/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	S.d	-2,718	106.33	-26	-5	507	D
5/20/26 16:05	5/19/26	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Powl Brian T.	CA	O	Chief Co	S	-3	9.21	0	0	184	D
5/20/26 16:05	5/19/26	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ford Kathleen	CA	O	COO	S	-20	9.08	-2	-1	154	D
5/20/26 16:05	5/18/26	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bair Teresa Brophy	CA	O	GC	S	-21	9.38	-2	-1	227	D
5/20/26 16:05	5/18/26	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Freund John Gordon	MA	D		S	-1	34.05	0	0	116	D
5/20/26 16:01	5/18/26	GYRE	Gyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ye Weiguo	CA	O	COO	S.dm	-59	6.38	-9	-1	700	D
5/20/26 16:00	5/19/26	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	S.d	-265	75.69	-4	-2	154	D
5/19/26 19:15	5/18/26	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	S.d	-11	27.55	0	-1	63	D
5/19/26 18:48	5/15/26	PHVS	Pharvaris N.V.	P7	Health	Drug	Pharmaceutical Preparations	Glassman Robert	MA	D		S.d	-298	29.82	-10	-49	11	D
5/19/26 18:44	5/15/26	PHVS	Pharvaris N.V.	P7	Health	Drug	Pharmaceutical Preparations	Abele Stefan Andreas	MA	O	Chief Te	S	-261	29.82	-9	-20	35	D
5/19/26 18:42	5/15/26	PHVS	Pharvaris N.V.	P7	Health	Drug	Pharmaceutical Preparations	Souverijns Wim	MA	O	Chief Co	S	-299	29.92	-10	-18	45	D
5/19/26 16:32	5/18/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Edgemond James	MD	O	CFO,TREA	S.d	-5,673	567.31	-10	-35	19	D
5/19/26 16:31	5/18/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-5,387	567.04	-10	-1	680	D
5/19/26 16:30	5/18/26	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Trimarchi Thomas	CA	O	P,CFO	S	-888	65.08	-14	-4	359	D
5/19/26 16:25	5/15/26	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scott Randal W.	CA	D		S.d	-671	67.15	-10	-39	16	D
5/19/26 16:18	5/15/26	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Du Ying	MA	DO	Chairper	S.dm	-1,987	19.87	-100	-8	1,123	D
5/19/26 16:15	5/15/26	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	German Christopher Paul	MA	O	Corporat	S.d	-428	92.21	-5	-100	0	D
5/19/26 16:10	5/15/26	AVTX	Avalo Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Doyle Mittie	PA	O	Chief Me	S.d	-56	18.76	-3	-45	4	D
5/19/26 16:05	5/18/26	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yea Christopher	MA	O	CHIEF DE	S.d	-30	26.76	-1	0	227	D
5/19/26 16:05	5/15/26	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Coughlin Timothy	CA	D		S	-141	43.49	-3	-6	52	D
5/19/26 16:05	5/18/26	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Desrosier Thomas	MA	O	See Rema	S.d	-1	7.53	0	-1	8	D
5/19/26 16:05	5/18/26	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shaff Eric D.	MA	D		S.d	-2	7.53	0	-2	12	D
5/19/26 16:05	5/18/26	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Henn Matthew R	MA	O	See Rema	S.d	-1	7.53	0	-1	8	D
5/19/26 16:05	5/18/26	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brady Kelly	MA	O	See Rema	S.d	0	7.53	0	-1	9	D
5/19/26 16:05	5/15/26	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	Bunnage Mark E.	MA	O	EVP,Chie	S	-15	453.45	0	0	7	D
5/19/26 16:04	5/18/26	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Audhya Paul K.	MA	O	CHIEF ME	S.d	-28	26.76	-1	-1	144	D
5/19/26 16:04	5/15/26	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	Bozic Carmen	MA	O	EVP,CMO	S	-614	453.45	-1	-5	25	D
5/19/26 16:03	5/18/26	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	S.d	-30	26.76	-1	0	468	D
5/19/26 16:03	5/15/26	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Raab Michael	MA	DO	P,CEO	S.d	-262	6.28	-42	-2	1,800	D
5/18/26 21:27	5/18/26	MPLT	Maplight Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kroeger Christopher A.	CA	DO	CEO	S	-3,215	27.19	-118	-8	1,394	D
5/18/26 20:32	5/15/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ramasastry Saira	CA	D		S.d	-219	109.47	-2	-100	0	D
5/18/26 18:41	5/18/26	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Suliman Shehnaaz	CA	D		S.d	-144	25.12	-6	-17	28	D
5/18/26 18:18	5/15/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-5,397	568.11	-10	-1	680	D
5/18/26 18:07	5/18/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Agarwal Arjun	CA	O	SVP,Fina	S.d	-608	59.07	-10	-39	16	D
5/18/26 17:36	5/18/26	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Soergel David	PA	O	Chief Me	S	-435	515.90	-1	-7	11	D
5/18/26 16:25	5/15/26	ACIU	Ac Immune Sa	V8	Health	Drug	Pharmaceutical Preparations	Pfeifer Andrea		DO	CEO	S	-28	2.79	-10	0	3,834	D
5/18/26 16:24	5/15/26	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	S.d	-254	20.29	-13	-6	192	D
5/18/26 16:15	5/15/26	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Freund John Gordon	MA	D		S.d	-143	34.54	-4	-3	116	D
5/18/26 16:05	5/14/26	NBP	Novabridge Biosciences	E9	Health	Drug	Pharmaceutical Preparations	Cao Sean Wuxiong	MD	DO	See Rema	S	-43	1.99	-21	-38	35	D
5/18/26 16:02	5/14/26	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Lippman Evan		O	EVP,Busi	S.d	-1,482	35.58	-42	-49	44	D
5/18/26 16:01	5/14/26	GYRE	Gyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ye Weiguo	CA	O	COO	S.dm	-195	6.79	-29	-4	700	D
5/18/26 16:00	5/14/26	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Kalif Eliyahu Sharon		O	EVP,CFO	S	-5,457	35.61	-153	-47	172	D
5/18/26 14:03	5/15/26	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Barber Daniel	NJ	O	P,CEO	S	-35	4.29	-8	-1	661	D
5/15/26 20:17	5/15/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goncalves Joana	CA	O	Chief Me	S.d	-433	61.85	-7	-17	33	D
5/15/26 18:59	5/13/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	S.m	-4,299	57.32	-75	-3	2,382	I
5/15/26 18:15	5/13/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	S.dm	-356	78.49	-5	-2	243	D
5/15/26 17:04	5/14/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-5,458	574.48	-10	-1	680	D
5/15/26 17:04	5/14/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Edgemond James	MD	O	CFO,TREA	S.d	-5,745	574.48	-10	-35	19	D
5/15/26 17:00	5/15/26	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Crombez Eric	OH	D		S	-145	5.53	-26	-41	37	D
5/15/26 16:46	5/14/26	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Edmondson Frazor Titus III	MA	O	GC	S	-71	20.19	-4	-15	20	D
5/15/26 16:45	5/13/26	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Du Ying	MA	DO	Chairper	S.dm	-2,003	20.03	-100	-8	1,123	D
5/15/26 16:39	5/13/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry		O	SVP,GC	S.d	-103	310.72	0	0	318	D
5/15/26 16:38	5/14/26	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Urist Marshall	NY	O	EVP,Rese	S	-726	53.06	-14	-21	51	D
5/15/26 16:37	5/14/26	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Norden Gregory	NY	D		S	-161	53.00	-3	-2	192	D
5/15/26 16:24	4/2/26	SNSE	Sensei Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Millennium Management LLC	NY	T		S.m	-538	31.51	-17	-11	134	I
5/15/26 16:22	3/31/26	SNSE	Sensei Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Millennium Management LLC	NY	T		S.m	-77	28.07	-3	-2	148	I
5/15/26 16:22	3/26/26	SNSE	Sensei Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Millennium Management LLC	NY	T		S.m	-89	27.50	-3	-2	146	I
5/15/26 16:08	5/14/26	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Poulton Stuart	MA	O	EVP,Chie	S	-4	9.50	0	0	95	D
5/15/26 16:08	5/13/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	S	-961	116.18	-8	-10	71	D
5/15/26 16:07	5/13/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Adsett Roger	NJ	O	COO	S	-678	116.18	-6	-5	101	D
5/15/26 16:07	5/13/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Flammer Martina M.D.	NJ	O	Chief Me	S.m	-2,129	116.12	-18	-22	65	D
5/15/26 16:07	5/14/26	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rangwala Reshma	MA	O	EVP,Chie	S	-4	9.50	0	-1	57	D
5/15/26 16:07	5/13/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Smith Michael Alexander	NJ	O	GC	S	-477	116.18	-4	-8	48	D
5/15/26 16:06	5/13/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	S	-1,543	116.18	-13	-2	522	D
5/15/26 16:05	5/14/26	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Sohanya Roshan	MA	O	EVP,Chie	S	-3	9.50	0	0	108	D
5/15/26 16:05	5/13/26	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Lurker Nancy	MA	D		S	-162	35.97	-5	-20	18	D
5/15/26 16:04	5/14/26	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Abate Kristin	MA	O	Chief Ac	S	-1	9.50	0	0	24	D
5/15/26 16:03	5/14/26	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Paulson Richard A.	MA	DO	P,CEO	S	-21	9.50	-2	-1	270	D
5/15/26 16:02	5/14/26	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mano Michael	MA	O	EVP,CLO,	S	-3	9.50	0	0	94	D
5/14/26 21:08	5/1/26	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Kozarich John W	FL	D		S.dm	-563	225.14	-3	-6	42	D
5/14/26 20:06	5/12/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Patel Dinesh V Ph D	CA	DO	P,CEO	S.ad	-7,509	100.12	-75	-13	523	D
5/14/26 20:05	5/12/26	STTK	Shattuck Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shukla Abhinav A.	TX	O	Chief Te	S.d	-14	7.01	-2	-2	81	D
5/14/26 20:00	5/12/26	STTK	Shattuck Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pandite Arundathy N.	TX	O	Chief Me	S	-198	6.61	-30	-15	166	D
5/14/26 19:05	5/12/26	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lu Hongbo	CA	D		S	-228	76.88	-3	-5	52	D
5/14/26 17:54	5/13/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-5,497	578.65	-10	-1	680	D
5/14/26 16:26	5/14/26	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	S	-584	77.92	-8	-2	404	D
5/14/26 16:22	5/13/26	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Martin	NJ	O	GC	S	-12	3.61	-3	0	679	D
5/14/26 16:19	5/13/26	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shah Gaurav	NJ	O	CEO	S	-10	3.61	-3	0	1,450	D
5/14/26 16:16	5/13/26	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Militello John	NJ	O	See Rema	S	-3	3.61	-1	-1	90	D
5/14/26 16:10	5/12/26	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	Bozic Carmen	MA	O	EVP,CMO	S	-3,145	450.00	-7	-21	26	D
5/14/26 16:05	5/13/26	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedl-Naderer Johanna	MA	O	Chief Co	S	-4	18.36	0	0	154	D
5/14/26 16:04	5/13/26	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kerr Douglas	MA	O	Chief Me	S	-29	18.36	-2	-1	170	D
5/14/26 16:03	5/13/26	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lucera Erick	MA	O	CFO	S	-27	18.36	-1	-1	124	D
5/14/26 16:02	5/13/26	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cox John	MA	DO	CEO,P	S	-61	18.36	-3	-1	443	D
5/13/26 21:42	5/11/26	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	S.dm	-653	28.91	-23	-26	63	D
5/13/26 20:30	5/12/26	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Binder Steven B.	CT	D		S	-56	3.29	-17	-2	808	D
5/13/26 20:30	5/12/26	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Thomson David	CT	O	EVP Genl	S	-10	3.29	-3	0	826	D
5/13/26 20:22	5/11/26	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Walsh Patrick D	NJ	D		S.m	-1,127	80.66	-14	-27	38	D
5/13/26 20:00	5/11/26	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dobek Maria	CA	O	VP,Accou	S	-29	14.17	-2	-6	32	D
5/13/26 19:43	5/11/26	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vairavan Latha	CA	O	SVP CFO	S	-9	21.05	0	-1	86	D
5/13/26 19:42	5/11/26	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	S	-5	21.05	0	0	120	D
5/13/26 19:06	5/11/26	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Third Rock Ventures V, L.P.	MA	T		S	-5,377	40.24	-134	-2	7,268	D
5/13/26 18:04	5/11/26	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ugwumba Chidozie	AR	T		S.m	-604	6.33	-95	-48	103	I
5/13/26 16:50	5/11/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Flammer Martina M.D.	NJ	O	Chief Me	S.d	-1,300	100.40	-13	-13	83	D
5/13/26 16:32	5/11/26	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Thompson Rahsaan	MA	O	Chief Le	S	-20	11.30	-2	-4	48	D
5/13/26 16:31	5/12/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-5,495	578.38	-10	-1	680	D
5/13/26 16:31	5/12/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mesa Nilda	MD	D		S	-150	581.94	0	-5	5	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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