Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
9/25/25 20:59	9/23/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	DT		S.dm	-227	2.34	-97	-44	124	I
9/25/25 19:44	9/23/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	S	-30	20.03	-2	0	932	I
9/25/25 19:42	9/23/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	S	-56	20.03	-3	0	919	I
9/25/25 16:31	9/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Causey Christopher	MD	D		S.d	-440	440.00	-1	-17	5	D
9/25/25 16:30	9/23/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,409	426.14	-8	-1	644	D
9/24/25 20:35	9/22/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Waddill William D.	CA	D		S	-257	64.25	-4	-44	5	D
9/24/25 19:42	9/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saccomano Nicholas A	CO	DO	P,CEO	S	0	2.62	0	-2	4	D
9/24/25 19:41	9/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leverone Jason A.	CO	O	CFO	S	-1	2.62	0	-2	13	D
9/24/25 19:00	9/24/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Bush Tia L	X0	O	Chief Te	S.d	-840	24.00	-35	-22	122	D
9/24/25 18:49	9/22/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		S.m	-21	1.76	-12	0	4,357	I
9/24/25 17:11	9/23/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Aryeh Jason	FL	D		S	-1,708	170.81	-10	-7	126	D
9/24/25 16:30	9/22/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chacko Jacob	CA	DO	P,CEO	S	-1,350	10.80	-125	-16	656	D
9/24/25 16:30	9/22/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Calkins Daniel	MA	O	CFO	S.m	-1	9.13	0	0	110	D
9/24/25 16:14	9/23/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	S.d	-1,394	47.23	-30	-1	2,146	D
9/24/25 16:05	9/22/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Reed Elizabeth E	CA	O	GC,GC	S.d	-250	25.00	-10	-10	90	D
9/24/25 06:35	9/22/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	S.d	-9,368	416.35	-23	-89	3	I
9/23/25 21:00	9/19/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	S.dm	-25,525	14.92	-1,711	-53	1,505	D
9/23/25 17:32	9/22/25	XOMA	Xoma Royalty Corp	NV	Health	Drug	Pharmaceutical Preparations	Burns Thomas M.	CA	O	SVP,Fina	S.d	-156	35.99	-4	-10	40	D
9/23/25 17:14	9/19/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	S	-136	19.39	-7	-1	933	I
9/23/25 17:07	9/23/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	S.d	-99	49.28	-2	-1	141	D
9/23/25 16:57	9/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	S.d	-90	40.58	-2	-5	39	D
9/23/25 16:33	9/19/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	Versant Venture Capital Vi, L.P.	CA	T		S	-4,069	1.40	-2,903	-100	0	M
9/23/25 16:30	9/19/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	DT		S.d	-181	2.35	-77	-39	121	I
9/23/25 16:22	9/22/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	S.d	-780	47.02	-17	-1	2,128	D
9/22/25 19:49	9/22/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	O'Malley Brendan M.	OH	O	SVP,GC	S	-4	5.43	-1	0	360	D
9/22/25 19:00	9/22/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jacobson Mark L.	NY	O	COO	S.d	-1,160	115.96	-10	-100	0	D
9/22/25 18:32	9/18/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	Bendheim Jack	NJ	DOT	P,CEO	S.d	-283	40.26	-7	-8	78	I
9/22/25 17:25	9/19/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Barber Daniel	NJ	DO	P,CEO	S	-2	6.00	0	0	1,015	D
9/22/25 17:14	9/19/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Davis Krista	MN	O	SVP,CHRO	S	-98	98.04	-1	-2	60	D
9/22/25 16:39	9/19/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,314	414.19	-8	-1	644	D
9/22/25 16:00	9/19/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-18,059	763.10	-24	0	95,607	D
9/19/25 21:17	9/19/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunlop A. Sinclair	MA	D		S	-714	22.95	-31	-12	223	I
9/19/25 20:46	9/18/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Kirk Randal J	VA	DT		S.dm	-18,654	3.73	-5,000	-4	128,722	I
9/19/25 19:12	9/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	S.m	-116	19.29	-6	-1	922	I
9/19/25 18:23	9/18/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Huizenga Theodore Alan	CA	O	SVP,Chie	S	-2	29.17	0	0	50	D
9/19/25 18:03	9/17/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		S.m	-20	1.77	-11	0	4,368	I
9/19/25 16:50	9/17/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	DT		S.dm	-57	2.47	-23	-19	98	I
9/19/25 16:49	9/19/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Olian Judy D.	MD	D		S	-748	415.43	-2	-26	5	D
9/19/25 16:05	9/17/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ceesay Abraham	MA	DO	CEO	S	-2,011	26.32	-76	-10	713	M
9/19/25 16:00	9/18/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-81,532	764.65	-107	0	95,630	D
9/18/25 21:30	9/16/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harmon Cyrus	CA	D		S.m	-205	8.19	-25	-3	861	M
9/18/25 18:49	9/16/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	Versant Venture Capital Vi, L.P.	CA	T		S.m	-2,502	1.49	-1,684	-37	2,903	M
9/18/25 18:16	9/16/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Stuglik Brian M	MA	D		S	-6	9.99	-1	-1	102	D
9/18/25 18:14	9/16/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Gagnon Robert E.	MA	D		S	-3	9.99	0	-1	42	D
9/18/25 18:11	9/16/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Paterson Dan	MA	DO	P,CEO	S	-4	9.99	0	0	442	D
9/18/25 16:45	9/16/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John	V8	DO	CEO	S	-9,056	325.71	-28	0	53,506	D
9/18/25 16:31	9/18/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	S.d	-4,468	406.17	-11	-23	37	D
9/18/25 16:30	9/17/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,218	402.29	-8	-1	644	D
9/18/25 16:06	9/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Looker Benjamin	MI	O	GC	S	-18	2.80	-6	-2	394	D
9/18/25 16:06	9/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Koenig Sheldon L.	MI	DO	P,CEO	S	-79	2.79	-28	-2	1,519	D
9/18/25 16:06	9/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Halladay Benjamin	MI	O	CFO	S	-20	2.81	-7	-1	475	D
9/18/25 16:01	9/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	S	-122	24.34	-5	-3	179	D
9/17/25 20:08	9/15/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chopas James George	MA	O	VP,Chief	S	-5	24.19	0	0	53	D
9/17/25 19:39	9/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Tross Stuart A	CT	O	Chief Pe	S	-251	5.34	-47	-4	1,032	D
9/17/25 19:00	9/16/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jacobson Mark L.	NY	O	COO	S.d	-5,241	114.48	-46	-100	0	D
9/17/25 18:06	9/16/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Third Rock Ventures Iv, L.P.	MA	T		S	-2,559	7.04	-364	-2	14,364	D
9/17/25 17:01	9/15/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meisner Lara	MA	O	GC	S.d	-182	11.49	-16	-100	0	D
9/17/25 16:45	9/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	S.d	-598	36.46	-16	-32	35	D
9/17/25 16:31	9/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	S.d	-2,135	79.08	-27	-10	249	D
9/17/25 16:30	9/16/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-1,601	400.27	-4	-1	644	D
9/17/25 16:30	9/15/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Singh Raman	NC	D		S.d	-1,175	25.81	-46	-59	31	D
9/17/25 16:15	9/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	S	-206	24.19	-9	-2	418	D
9/17/25 16:03	9/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Teresa	CA	O	CHRO	S.d	-621	41.41	-15	-13	97	D
9/17/25 16:02	9/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	S.d	-70	45.41	-2	-4	39	D
9/17/25 06:02	9/15/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	S.d	-9,013	400.56	-23	-89	3	I
9/16/25 21:45	9/12/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunton Alan W	NJ	D		S.d	-131	13.13	-10	-20	40	D
9/16/25 19:45	9/12/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		S.m	-8	1.85	-4	0	4,380	I
9/16/25 19:36	9/12/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tabuteau Herriot	NY	DOT	CEO	S.dm	-7,362	117.08	-63	-1	7,352	D
9/16/25 18:54	9/15/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	S	-409	36.00	-11	-12	82	D
9/16/25 18:16	9/16/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	S	-175	21.40	-8	-4	197	D
9/16/25 18:06	9/12/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hamilton James C	CA	O	Chief Me	S	-450	30.00	-15	-6	232	D
9/16/25 18:00	9/15/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Schneyer Mark C.	CA	O	EVP,CFO	S	-83	23.65	-3	-7	43	D
9/16/25 16:56	9/12/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	S.d	-110	64.58	-2	-3	57	D
9/16/25 16:35	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Paulson Richard A.	MA	DO	P,CEO	S	-8	6.43	-1	-1	84	D
9/16/25 16:34	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mano Michael	MA	O	SVP,GC,S	S	-2	6.43	0	-1	21	D
9/16/25 16:33	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Poulton Stuart	MA	O	EVP,Chie	S	-3	6.43	0	-1	28	D
9/16/25 16:32	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rangwala Reshma	MA	O	EVP,Chie	S	-3	6.43	0	-1	29	D
9/16/25 16:31	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Sohanya Roshan	MA	O	EVP,Chie	S	-2	6.43	0	-1	36	D
9/16/25 16:30	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Abate Kristin	MA	O	Chief Ac	S	0	6.43	0	0	10	D
9/16/25 07:44	9/12/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,207	400.93	-8	-1	644	D
9/15/25 19:16	9/12/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	S	-39	98.42	0	-1	76	D
9/15/25 18:37	9/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	S.d	-131	21.85	-6	-5	111	D
9/15/25 17:39	9/12/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mottola Frank	MD	O	SVP,Chie	S.d	-229	45.87	-5	-24	15	D
9/15/25 16:47	9/15/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	S	-249	49.77	-5	-1	377	D
9/15/25 16:26	9/12/25	MRSN	Mersana Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Huber Martin H. Jr.	MA	DO	P,CEO	S.d	-15	7.31	-2	-17	10	D
9/15/25 16:23	9/12/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Schaeffer Orlov S Nicole	NJ	O	Chief Pe	S.d	-11,130	145.45	-77	-68	36	D
9/15/25 16:22	9/12/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Sharoky Melvin Md	NJ	D		S	-1,454	145.39	-10	-3	295	M
9/15/25 12:45	9/12/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Callicutt Jack W	GA	O	CFO	S.d	-56	6.44	-9	-53	8	D
9/15/25 12:45	9/12/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Lewis Joel	GA	DO	P,CEO	S.d	-89	6.36	-14	-2	835	D
9/12/25 21:45	9/12/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Todisco Joseph	NJ	O	CEO	S.d	-650	13.00	-50	-9	509	D
9/12/25 20:39	9/11/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	S	-25	43.02	-1	0	257	D
9/12/25 20:39	9/11/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	S	-28	43.02	-1	-1	91	D
9/12/25 20:38	9/11/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	White William Richard	CA	O	CFO	S	-28	43.02	-1	-1	58	D
9/12/25 20:36	9/11/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	S	-24	43.02	-1	0	167	D
9/12/25 20:36	9/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	S.dm	-1,375	43.23	-32	-6	474	D
9/12/25 20:00	9/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brege Laura	CA	D		S.d	-1,265	74.40	-17	-52	16	D
9/12/25 20:00	9/12/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bjerkholt Eric	CA	O	CFO	S.d	-728	76.01	-10	-19	40	D
9/12/25 18:00	9/11/25	VTRS	Viatris Inc	DE	Health	Drug	Pharmaceutical Preparations	Le Goff Corinne	PA	O	Chief Co	S	-72	10.25	-7	-17	35	D
9/12/25 17:30	9/11/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Hariri Robert J	TN	D		S.d	-243	9.71	-25	-33	51	D
9/12/25 17:09	9/11/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Persky Marla	IL	D		S	-120	7.72	-16	-9	148	D
9/12/25 17:09	9/10/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S	-900	1.80	-500	-8	5,975	I
9/12/25 16:42	9/11/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lonial Sagar	NC	D		S	-672	32.24	-21	-18	94	D
9/12/25 16:38	9/10/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	S.d	-3,257	325.53	-10	-4	238	D
9/12/25 16:30	9/10/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	S.d	-294	78.83	-4	-5	66	D
9/12/25 16:11	9/12/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parschauer Karah Herdman	CA	O	EVP,GC	S	-76	31.17	-2	-3	73	D
9/12/25 16:07	9/11/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flanagan W. Michael	CA	O	Chief Sc	S.d	-779	38.94	-20	-20	80	D
9/12/25 16:01	9/10/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	S	-523	26.17	-20	-10	184	I
9/11/25 21:45	9/9/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zelnick Kaufman Beth	NJ	O	GC	S.d	-670	13.41	-50	-22	180	D
9/11/25 21:45	9/9/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hurlburt Elizabeth	NJ	O	COO	S.dm	-712	13.18	-54	-23	177	D
9/11/25 21:01	9/9/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Robin Howard W	CA	DO	P,CEO	S	-311	46.69	-7	-12	49	D
9/11/25 20:56	9/9/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	Bendheim Jack	NJ	DOT	P,CEO	S.m	-857	40.59	-21	-28	55	I
9/11/25 20:38	9/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		S.d	-159	72.45	-2	-100	0	D
9/11/25 19:43	9/9/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		S.m	-41	1.94	-21	0	4,384	I
9/11/25 19:41	9/10/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,184	397.97	-8	-1	644	D
9/11/25 18:57	9/9/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	Beindorff Michael A	UT	D		S	-49	11.44	-4	-3	120	M
9/11/25 17:50	9/9/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Bush Tia L	X0	O	Chief Te	S.dm	-1,046	21.00	-50	-29	122	D
9/11/25 17:47	9/9/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	S.dm	-840	21.00	-40	-27	111	D
9/11/25 17:45	9/9/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	S.d	-140	20.00	-7	-3	206	D
9/11/25 17:20	9/9/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Savitz Ryan	NY	O	CFO,CBO	S.d	-700	35.00	-20	-100	0	D
9/11/25 17:10	9/9/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Lai	V8	O	Global H	S	-1,750	350.06	-5	0	1,625	I
9/11/25 17:05	9/9/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	S.d	-743	62.16	-12	-25	35	D
9/11/25 17:04	9/9/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	S.d	-1,356	64.56	-21	-27	57	D
9/11/25 16:05	9/9/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Reitan Colleen F	MA	D		S.d	-8,417	467.60	-18	-96	1	D
9/10/25 20:12	9/8/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	S	-135	20.24	-7	-2	283	I
9/10/25 19:48	9/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	S.d	-552	44.17	-13	-7	167	D
9/10/25 18:21	9/8/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watanabe Todd	CA	DO	See Rema	S.m	-178	17.54	-10	-1	1,125	D
9/10/25 17:50	9/8/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ramasastry Saira	CA	D		S.d	0	0.00	-17	-100	0	D
9/10/25 17:39	9/9/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kooij Louise Frederika	P7	O	Chief Ac	S.d	-3,874	25.83	-150	-91	15	D
9/10/25 17:00	9/8/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Elsbernd Brian	FL	O	Chief Co	S.d	-609	20.30	-30	-10	271	D
9/10/25 16:31	9/8/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	S.dm	-6,482	395.82	-16	-86	3	I
9/10/25 16:31	9/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Malcolm Jan	MD	D		S	-280	400.29	-1	-57	1	D
9/10/25 16:31	9/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-3,188	398.55	-8	-1	644	D
9/10/25 16:30	9/10/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Thompson Tommy G	MD	D		S.d	-1,839	403.36	-5	-17	22	D
9/10/25 16:15	9/8/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gault Cheryl	MA	O	COO	S.d	-192	38.33	-5	-3	172	D
9/10/25 16:13	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	S.d	-103	51.29	-2	-1	141	D
9/10/25 16:02	9/8/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sullivan Timothy Eugene	MA	O	CFO	S.d	-1,190	27.85	-43	-20	171	M
9/10/25 15:09	9/5/25	CYCC	Cyclacel Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kua Khai Loon	N8	T		S	-134	7.01	-19	-5	385	D
9/9/25 21:07	9/9/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sibold William John	PA	DO	P,CEO	S	-3,244	445.63	-7	-7	102	D
9/9/25 19:02	9/8/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	S.d	-116	15.84	-7	-2	395	D
9/9/25 18:37	9/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Schoenberg Mark	NJ	O	Chief Me	S.d	-17	19.11	-1	-1	149	D
9/9/25 18:32	9/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Smith Jason Drew	NJ	O	GC	S.d	-29	19.11	-2	-3	43	D
9/9/25 18:30	9/5/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	S.d	-16	62.00	0	-1	35	D
9/9/25 18:30	9/5/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	S	-358	59.60	-6	-7	83	D
9/9/25 17:53	9/5/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Troy Edward	CA	D		S.d	-1,475	50.00	-30	-30	68	D
9/9/25 17:31	9/5/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Sanders Corazon (Corsee) D.	V8	D		S.d	-898	337.00	-3	-4	57	D
9/9/25 16:40	9/5/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Breedlove Robert Charles	NJ	O	Principa	S	-6	12.09	0	-1	55	D
9/9/25 16:31	9/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cox John	MA	DO	CEO,P	S	-35	13.41	-3	-1	272	D
9/9/25 16:26	9/5/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Washburn Theodore James Jr.	MA	O	Principa	S	-315	36.87	-9	-91	1	D
9/9/25 16:21	9/8/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	S.d	-293	46.29	-6	-1	1,112	D
9/9/25 16:15	9/5/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Third Rock Ventures Iv, L.P.	MA	T		S.m	-5,109	7.00	-729	-5	14,728	D
9/8/25 20:32	9/4/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Zalevsky Jonathan	CA	O	Chief R,	S	-58	33.52	-2	-9	17	D
9/8/25 20:31	9/4/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Robin Howard W	CA	DO	P,CEO	S.m	-431	36.42	-12	-17	56	D
9/8/25 19:06	9/4/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jung Cassie	NJ	O	COO	S.d	-311	5.00	-62	-18	285	D
9/8/25 18:55	9/4/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		S.m	-17	1.91	-9	0	4,405	I
9/8/25 18:45	9/8/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Metzger Michael A	NY	DO	CEO	S.d	-2,582	16.41	-157	-34	299	D
9/8/25 18:06	9/5/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCormick Frank	CA	D		S.d	-3,934	53.16	-74	-7	963	D
9/8/25 18:05	9/4/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	S.m	-4,176	52.20	-80	-1	5,777	I
9/8/25 17:37	9/4/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ceesay Abraham	CA	D		S	-64	27.19	-2	-21	9	D
9/8/25 17:14	9/4/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Matsuda Masaru	CA	O	See Rema	S	-584	16.16	-36	-18	161	D
9/8/25 17:13	9/5/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Boyd Peter E.	NJ	O	See Rema	S	-80	5.30	-15	-5	288	D
9/8/25 16:38	9/4/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	S.dm	-3,506	35.54	-99	-69	44	D
9/8/25 16:37	9/4/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Moat Ross	X0	O	CHIEF CO	S	-124	35.31	-4	-27	9	D
9/8/25 16:37	9/8/25	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Carson Seana	NJ	O	EVP,GC	S	-98	7.31	-13	-3	500	D
9/8/25 16:31	9/5/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	S.d	-2,557	46.01	-56	-3	2,116	D
9/8/25 16:06	9/4/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedl-Naderer Johanna	MA	O	Chief Co	S.m	-14	13.29	-1	-1	95	D
9/8/25 16:03	9/4/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kerr Douglas	MA	O	Chief Me	S.m	-59	13.30	-4	-5	88	D
9/8/25 14:01	9/5/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Huizenga Theodore Alan	CA	O	SVP,Chie	S	-3	31.39	0	0	50	D
9/5/25 19:48	9/5/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Azoy Alexander	CA	O	Chief Ac	S	-19	11.88	-2	-5	30	D
9/5/25 19:43	9/5/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saad Mark E	NY	D		S.d	-1,142	125.07	-9	-47	10	D
9/5/25 18:56	9/5/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Boyce Sarah	CA	DO	P,CEO	S.d	-2,497	49.95	-50	-14	306	D
9/5/25 18:32	9/3/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mosbrooker Eric	CA	O	Chief Co	S.d	-309	47.07	-7	-11	55	D
9/5/25 18:00	9/4/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Taubert Jennifer L	NJ	O	EVP,WWC.	S.d	-10,041	177.81	-56	-24	178	D
9/5/25 17:06	9/3/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kooij Louise Frederika	P7	O	Chief Ac	S	-453	25.09	-18	-55	15	D
9/5/25 17:01	9/3/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Ramaswamy Vivek	DC	T		S.m	-22,456	12.65	-1,776	-4	48,866	D
9/5/25 17:00	9/3/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Elsbernd Brian	FL	O	Chief Co	S.dm	-987	19.74	-50	-21	189	D
9/5/25 16:30	9/4/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	S.d	-4,237	385.21	-11	-23	37	D
9/5/25 16:30	9/3/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Singh Raman	NC	D		S	-221	29.42	-8	-19	31	D
9/5/25 16:05	9/3/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Cline Christopher R.	CA	O	CFO	S.m	-11	18.51	-1	-1	92	D
9/5/25 16:03	9/4/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fitzpatrick Jennifer	MA	O	GC	S.d	-237	23.12	-10	-100	0	D
9/4/25 21:02	9/2/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Zalevsky Jonathan	CA	O	Chief R,	S	-15	30.10	0	-2	19	D
9/4/25 21:01	9/2/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Robin Howard W	CA	DO	P,CEO	S	-45	30.16	-2	-2	68	D
9/4/25 20:41	9/2/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	S	-553	49.67	-11	-23	37	D
9/4/25 20:40	9/2/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Wender Joseph H	CA	D		S.m	-1,612	57.58	-28	-20	109	I
9/4/25 20:38	9/2/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Parshall B Lynne	CA	D		S	-1,018	50.91	-20	-23	66	D
9/4/25 20:38	9/3/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	S.d	-12,295	60.32	-204	-53	180	D
9/4/25 20:38	9/3/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Klein Joseph III	CA	D		S.d	-1,680	60.00	-28	-63	16	I
9/4/25 20:37	9/3/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Klein Joseph III	CA	D		S.d	-1,680	60.00	-28	-63	16	I
9/4/25 20:37	9/2/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Geary Richard S	CA	O	EVP,Chie	S	-504	50.37	-10	-11	80	D
9/4/25 20:36	9/3/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	S.d	-193	61.02	-3	-17	16	D
9/4/25 20:34	9/2/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Wender Joseph H	CA	D		S.m	-1,612	57.58	-28	-20	109	I
9/4/25 20:34	9/3/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	S.d	-1,946	59.34	-33	-48	35	D
9/4/25 20:29	9/2/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	S.dm	-5,397	60.03	-90	-61	57	D
9/4/25 20:29	9/2/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	S.dm	-2,301	59.14	-39	-30	89	D
9/4/25 20:28	9/3/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Loscalzo Joseph	CA	D		S.d	-962	60.15	-16	-31	36	D
9/4/25 20:28	9/3/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Schneider Eugene	CA	O	EVP,Chf	S.d	-1,195	60.81	-20	-28	52	D
9/4/25 19:59	9/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	S.d	-1,410	70.49	-20	-78	5	D
9/4/25 19:56	9/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	S.d	-351	70.25	-5	-33	10	D
9/4/25 19:54	9/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	S.d	-1,410	70.49	-20	-15	118	D
9/4/25 19:54	9/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Belanoff Joseph K	CA	DO	CEO	S	-2,821	70.53	-40	-1	2,821	I
9/4/25 19:47	9/2/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	S.d	-576	46.08	-13	-5	257	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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