Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
5/2/25 20:41	4/30/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Forbes William P	NC	O	EVP,Chie	2	M.d	0	0.00	16	15	123	D
5/2/25 20:32	4/30/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Duarte IRA	NC	O	EVP,CFO	2	M.d	0	0.00	16	13	136	D
5/2/25 20:27	5/1/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Petersen Floyd F.	CA	D		3	S	-54	27.11	-2		74	D
5/2/25 20:23	4/30/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Collard Craig A	NC	DO	CEO	3	M.d	0	0.00	111	35	426	D
5/2/25 20:00	5/1/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Kihara James	CA	O	PRINCIPA	8	M.d	63	5.45	12	96	24	D
5/2/25 20:00	5/2/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Kihara James	CA	O	PRINCIPA	8	S.d	-63	5.45	-12		24	D
5/2/25 20:00	5/1/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meyer Andrew Hollman	CA	O	Chief Bu	8	M.d	511	19.16	27	48	82	D
5/2/25 20:00	5/1/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meyer Andrew Hollman	CA	O	Chief Bu	8	S.d	-511	19.16	-27		82	D
5/2/25 19:59	5/1/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Schneyer Mark C.	CA	O	EVP,CFO	8	M.d	161	5.40	30	90	63	D
5/2/25 19:59	5/2/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Schneyer Mark C.	CA	O	EVP,CFO	8	S.d	-161	5.40	-30		63	D
5/2/25 19:55	5/1/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gallagher Kathleen P.	CA	O	Chief Pr	8	M.d	1,085	23.08	47	999%	51	D
5/2/25 19:55	5/1/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gallagher Kathleen P.	CA	O	Chief Pr	8	S.d	-1,085	23.08	-47		51	D
5/2/25 18:18	5/2/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Van Houte Hans	CA	O	CFO	4	S.d	-183	7.91	-23		40	D
5/2/25 17:04	4/30/25	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	Blount Sally E.	IL	D		1	S	-337	129.66	-3		34	D
5/2/25 16:55	5/1/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Lange Louis G	P7	D		3	M.d	0	0.00	3	13	28	I
5/2/25 16:43	5/1/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	15	M.d	18,149	55.85	325	79	738	I
5/2/25 16:43	5/1/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	15	S.d	-18,149	55.85	-325		738	I
5/2/25 16:38	5/1/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Hayden Michael R	CA	D		1	P	478	31.86	15	40	52	D
5/2/25 16:31	5/1/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	9	M.d	17,270	196.36	88		37	D
5/2/25 16:31	5/1/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	9	S.d	-17,270	196.36	-88		37	D
5/2/25 16:18	4/30/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Smart Dalton E. III	NJ	O	SVP Fin.	3	M.dm	714	70.66	10		8	D
5/2/25 16:17	5/1/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	8	M.dm	385	10.69	36	48	111	D
5/2/25 16:17	5/1/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	8	S.dm	-385	10.69	-36		111	D
5/2/25 16:14	4/30/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Romanelli Joseph	NJ	O	P,Human	1	M.dm	363	83.95	4	23	23	D
5/2/25 16:12	4/30/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Larson Betty D	NJ	O	EVP,CHRO	1	M.d	961	84.71	11		6	D
5/2/25 10:29	12/18/24	PRTA	Prothena Corp Public Ltd Co	L2	Health	Drug	Pharmaceutical Preparations	Scully William P	FL	T		1	P.m	2,750	13.26	207	29	927	M
5/1/25 20:59	4/29/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Fisher Andrew	X0	O	GC	2	M.d	234	2.09	112	45	360	D
5/1/25 20:59	4/29/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Fisher Andrew	X0	O	GC	2	S.d	-234	2.09	-112		360	D
5/1/25 20:58	4/29/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Zaccardelli David	X0	DO	P,CEO	2	M.d	811	2.54	320	2	14,377	D
5/1/25 20:58	4/29/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Zaccardelli David	X0	DO	P,CEO	2	S.d	-811	2.54	-320		14,377	D
5/1/25 20:56	4/29/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Rickard Kathleen A.	X0	O	Chief Me	3	M.d	971	4.86	200	8	2,661	D
5/1/25 20:56	4/29/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Rickard Kathleen A.	X0	O	Chief Me	3	S.d	-971	4.86	-200		2,661	D
5/1/25 20:55	4/29/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Hahn Mark W	X0	O	CFO	2	M.d	811	2.54	320	2	13,466	D
5/1/25 20:55	4/29/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Hahn Mark W	X0	O	CFO	2	S.d	-811	2.54	-320		13,466	D
5/1/25 20:53	4/29/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Sinha Vikas	X0	D		2	M.d	206	5.16	40	116	74	D
5/1/25 20:53	4/29/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Sinha Vikas	X0	D		2	S.d	-206	5.16	-40		74	D
5/1/25 19:23	4/30/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mack David J.	CT	D		4	M.d	0	0.00	32	66	81	D
5/1/25 19:07	4/30/25	ACRV	Acrivon Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Perceptive Advisors LLC	NY	T		3	S.m	-8,591	1.52	-5,657		9,717	I
5/1/25 18:26	4/29/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Moat Ross	X0	O	CHIEF CO	6	M.dm	3,810	19.08	200		28	D
5/1/25 18:26	4/29/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Moat Ross	X0	O	CHIEF CO	6	S.dm	-3,810	19.08	-200		28	D
5/1/25 18:24	4/29/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Ragosa Mark	X0	O	CFO	11	M.dm	6,360	19.27	330		27	D
5/1/25 18:24	4/29/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Ragosa Mark	X0	O	CFO	11	S.dm	-6,360	19.27	-330		27	D
5/1/25 16:53	4/29/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	10	M.d	2,183	32.85	66		19	D
5/1/25 16:53	4/29/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	10	S.d	-2,183	32.85	-66		19	D
5/1/25 16:52	4/29/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazabraud Yann	MA	O	EVP,Head	6	S.dm	-7,054	34.96	-202		44	D
5/1/25 16:45	4/29/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	6	M.dm	3,243	38.61	84		48	D
5/1/25 16:45	4/29/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	6	S.dm	-3,243	38.61	-84		48	D
4/30/25 19:35	4/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hansen Gwenn	CA	O	Chief Sc	2	M.d	39	3.15	12	25	62	D
4/30/25 19:35	4/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hansen Gwenn	CA	O	Chief Sc	2	S.d	-39	3.15	-12		62	D
4/30/25 19:35	4/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ring Christine	CA	O	GC	4	M.d	159	7.20	22	145	37	D
4/30/25 19:35	4/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ring Christine	CA	O	GC	4	S.d	-159	7.20	-22		37	D
4/30/25 18:59	4/28/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	11	M.d	295	8.82	34		23	D
4/30/25 18:59	4/28/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	11	S.d	-295	8.82	-34		23	D
4/30/25 17:07	4/30/25	ZNTL	Zentalis Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Myers Scott Dunseth	CA	D		1	P	29	1.40	21	8	281	D
4/30/25 16:45	4/28/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Selick Harold E	CA	D		1	M.d	12	1.16	11	32	44	D
4/30/25 16:17	3/27/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mpm Bioventures 2014, L.P.	MA	T		1	S.d	-2	1.05	-2	0	3,209	I
4/30/25 16:15	4/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	5	S.d	-39	4.69	-8		184	D
4/30/25 16:09	3/27/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Evnin Luke	MA	DT		1	S.d	-3	1.05	-2	0	4,310	I
4/30/25 16:08	3/27/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gadicke Ansbert	MA	T		1	S.d	-5	1.05	-4	0	6,719	I
4/29/25 18:14	4/25/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	Hirawat Samit	NJ	O	EVP,Chie	3	P.d	302	6.02	50	150	84	D
4/29/25 16:33	4/29/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	8	S	-4,870	42.96	-113		432	D
4/29/25 06:14	4/25/25	GLSI	Greenwich Lifesciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Snehal	TX	DOT	CEO,CFO	4	P	165	9.11	18	0	5,571	D
4/28/25 18:22	4/24/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	9	M.d	3,043	34.58	88	107	170	D
4/28/25 18:22	4/24/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	9	S.d	-3,043	34.58	-88		170	D
4/28/25 07:07	2/7/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Xiao Ting	MA	D		2	P	155	7.76	20	74	47	D
4/25/25 20:20	4/25/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Weinhoff Gregory M	X0	O	Chief Bu	4	S.d	-537	12.42	-43		134	D
4/25/25 19:01	3/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Slingsby Brian Taylor	WA	DT		1	P	3,500	13.50	259	3	8,904	I
4/25/25 16:01	3/24/25	GYRE	Gyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ye Weiguo	CA	O	COO	1	M.dm	488	0.7500	650		650	D
4/24/25 16:40	4/23/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rangwala Reshma	MA	O	EVP,Chie	2	S	-25	6.28	-4		29	D
4/24/25 16:28	4/22/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	5	S.d	-8,981	28.78	-312		6,306	I
4/24/25 16:06	4/22/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Militello John	NJ	O	See Rema	2	S	-34	9.87	-3		66	D
4/23/25 18:00	4/21/25	TBPH	Theravance Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	Farnum Rhonda	CA	O	SVP,COMM	1	S	-36	9.00	-4		370	D
4/23/25 17:09	4/21/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	2	S	-338	19.31	-18		1,003	I
4/23/25 16:30	4/22/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Ali Asif	CA	O	CFO	3	S.d	-1,914	37.13	-52		63	D
4/23/25 16:15	4/21/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	2	S	-84	13.61	-6		266	D
4/22/25 21:00	4/21/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,COO	8	M.dm	21,778	6.83	3,188		1,127	D
4/22/25 21:00	4/21/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,COO	8	S.dm	-21,778	6.83	-3,188		1,127	D
4/22/25 21:00	4/18/25	AMRN	Amarin Corp Plcuk	X0	Health	Drug	Pharmaceutical Preparations	Cohen Paul	NJ	D		1	M.d	0	0.00	1		0	D
4/22/25 21:00	4/18/25	AMRN	Amarin Corp Plcuk	X0	Health	Drug	Pharmaceutical Preparations	Odysseas Kostas D	CT	D		1	M.d	0	0.00	1		0	D
4/22/25 21:00	4/18/25	AMRN	Amarin Corp Plcuk	X0	Health	Drug	Pharmaceutical Preparations	Horn Keith	NJ	D		1	M.d	0	0.00	1		0	D
4/22/25 21:00	4/18/25	AMRN	Amarin Corp Plcuk	X0	Health	Drug	Pharmaceutical Preparations	Sullivan Diane E.	NJ	D		1	M.d	0	0.00	1		0	D
4/22/25 21:00	4/18/25	AMRN	Amarin Corp Plcuk	X0	Health	Drug	Pharmaceutical Preparations	Sterling Louis III	NJ	D		1	M.d	0	0.00	1	30	4	D
4/22/25 21:00	4/18/25	AMRN	Amarin Corp Plcuk	X0	Health	Drug	Pharmaceutical Preparations	Bonfiglio Patrice Eadon	NJ	D		1	M.d	0	0.00	1		0	D
4/22/25 21:00	4/18/25	AMRN	Amarin Corp Plcuk	X0	Health	Drug	Pharmaceutical Preparations	O'Connor Oliver	NJ	D		1	M.d	0	0.00	1		0	D
4/22/25 21:00	4/18/25	AMRN	Amarin Corp Plcuk	X0	Health	Drug	Pharmaceutical Preparations	Dipaolo Mark	CT	D		1	M.d	0	0.00	1		0	D
4/22/25 17:43	4/21/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Saha Saurabh	X0	DO	CEO	3	S.m	-2,476	15.00	-165		369	D
4/22/25 17:38	4/30/24	VREO	Vireo Growth Inc.	A1	Health	Drug	Pharmaceutical Preparations	Chicago Atlantic Opportunity Portfolio, LP	IL	T		1	P.dm	32	0.1600	197	0	110,909	D
4/22/25 16:33	4/22/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	15	M.d	1,292	33.07	39	39	140	D
4/22/25 16:33	4/22/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	15	S.d	-1,292	33.07	-39		140	D
4/22/25 16:30	4/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Dwek Raymond	MD	D		6	M.d	4,605	230.23	20		2	D
4/22/25 16:30	4/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Dwek Raymond	MD	D		6	S.d	-4,605	230.23	-20		2	D
4/22/25 07:01	4/17/25	PEPG	Pepgen Inc.	DE	Health	Drug	Pharmaceutical Preparations	McArthur James G	MA	DO	P,CEO	2	P	61	1.19	52	83	114	D
4/21/25 17:55	4/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	2	S	-342	19.57	-18		990	I
4/21/25 17:42	4/21/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Wierenga Wendall	CA	D		2	M.d	893	22.34	40		25	D
4/21/25 17:42	4/21/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Wierenga Wendall	CA	D		2	S.d	-893	22.34	-40		25	D
4/21/25 17:00	4/18/25	SIGA	Siga Technologies Inc	DE	Health	Drug	Pharmaceutical Preparations	Miller Larry R.	NY	O	GC	2	M.d	0	0.00	14	56	38	D
4/21/25 16:05	4/17/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Lundberg Sven Ante	P7	DO	P,CEO,PE	2	M.d	806	17.27	47		41	D
4/21/25 16:04	4/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Warren Eric	MI	O	Chief Co	3	S	-4	1.50	-3		370	D
4/21/25 16:03	4/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Halladay Benjamin	MI	O	CFO	3	S	-5	1.48	-4		482	D
4/18/25 17:27	4/16/25	GYRE	Gyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Eastling Thomas Wilson	CA	D		1	M.d	104	6.93	15		15	D
4/18/25 15:17	4/16/25	ZYME	Zymeworks Inc.		Health	Drug	Pharmaceutical Preparations	Ecor1 Capital, LLC	CA	DT		7	P.m	25,436	12.06	2,108	13	17,828	I
4/17/25 17:41	4/15/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kling Douglas F	P7	O	COO	8	M.dm	1,119	1.77	633		44	D
4/17/25 17:41	4/15/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kling Douglas F	P7	O	COO	8	S.dm	-1,119	1.77	-633		44	D
4/17/25 16:55	4/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	6	M.d	8,284	51.14	162	186	249	D
4/17/25 16:55	4/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	6	S.d	-8,284	51.14	-162		249	D
4/17/25 16:53	4/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Birchler Brian	CA	O	EVP,Corp	2	M.d	19	7.55	3	5	57	D
4/17/25 16:53	4/16/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Birchler Brian	CA	O	EVP,Corp	2	S.d	-19	7.55	-3		57	D
4/17/25 16:53	4/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Jenne Kyle	CA	O	EVP,Chf	2	M.d	86	5.61	15		11	D
4/17/25 16:53	4/16/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Jenne Kyle	CA	O	EVP,Chf	2	S.d	-86	5.61	-15		11	D
4/17/25 16:53	4/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	2	M.d	112	7.56	15	73	35	D
4/17/25 16:53	4/16/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	2	S.d	-112	7.56	-15		35	D
4/17/25 16:05	4/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	Samayoa Phillip	MA	O	CHIEF SC	1	M.d	0	0.00	1	1	129	D
4/17/25 16:05	4/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	McDonough Geoff	MA	DO	P,CEO	1	M.d	0	0.00	5	0	1,851	D
4/17/25 16:05	4/15/25	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Le-Nguyen Quoc	CA	O	See Rema	1	S	-91	5.95	-15		343	D
4/17/25 16:05	4/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	Paone Antoinette	MA	O	COO	1	M.d	0	0.00	2	7	23	D
4/17/25 16:05	4/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	Howze Yalonda	MA	O	GC	1	M.d	0	0.00	3	22	19	D
4/17/25 16:05	4/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	Conway Kevin John	MA	O	CFO	1	M.d	0	0.00	1	3	18	D
4/17/25 06:10	4/15/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Agah Ramtin	CA	DO	Chief Me	4	P	76	0.8323	91	9	1,113	D
4/16/25 18:00	4/15/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	7	M.d	1,931	32.87	59	159	96	D
4/16/25 18:00	4/15/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	7	S.d	-1,931	32.87	-59		96	D
4/16/25 18:00	4/15/25	VTRS	Viatris Inc	DE	Health	Drug	Pharmaceutical Preparations	Le Goff Corinne	PA	O	Chief Co	2	M.d	0	0.00	79		42	D
4/16/25 17:39	4/14/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ellis Andrea	CA	D		4	M.d	1,710	21.37	80		12	D
4/16/25 17:39	4/14/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ellis Andrea	CA	D		4	S.d	-1,710	21.37	-80		12	D
4/16/25 17:12	4/14/25	BGNE	Beigene, Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Xiaodong	E9	DH	Chair, S	7	M.d	33,358	128.94	259	3	10,325	D
4/16/25 17:12	4/14/25	BGNE	Beigene, Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Xiaodong	E9	DH	Chair, S	7	S.d	-33,358	128.94	-259		10,325	D
4/16/25 17:06	4/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	3	S.d	-95	10.32	-9		591	D
4/16/25 17:05	4/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	1	S	-192	13.57	-14		2,595	D
4/16/25 17:04	4/15/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	3	S.d	-55	9.43	-6		218	D
4/16/25 17:03	4/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	3	S.d	-126	10.95	-12		405	D
4/16/25 17:00	4/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	2	S	-174	10.21	-17		469	D
4/16/25 16:38	4/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	9	M.d	861	12.73	68	459	82	D
4/16/25 16:38	4/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	9	S.d	-861	12.73	-68		82	D
4/16/25 16:35	4/15/25	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	English Emily	MD	O	Chief Op	1	M.d	25	3.30	8	19	48	D
4/16/25 16:25	4/15/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Henderson John T	CA	D		2	M.d	248	10.67	23	54	66	D
4/16/25 16:25	4/15/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Henderson John T	CA	D		2	S.d	-248	10.67	-23		66	D
4/16/25 09:34	4/1/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Sabba Stephen L	NY	D		1	M.d	126	52.30	2	8	33	D
4/16/25 06:08	4/15/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bagai Shaun	CA	DO	CEO	3	P	23	0.8517	28	9	320	D
4/15/25 20:39	4/14/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	6	M.d	1,066	12.15	88	106	171	D
4/15/25 20:39	4/14/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	6	S.d	-1,066	12.15	-88		171	D
4/15/25 20:36	4/11/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levy Adam Scott	PA	O	CFO,Secr	1	S	-130	12.06	-11		215	D
4/15/25 20:33	4/11/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Congleton Jon	PA	DO	CEO	1	S	-187	12.19	-15		862	D
4/15/25 17:30	3/31/25	ASMB	Assembly Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McHutchison John G	CA	D		1	S	-7	9.85	-1		18	D
4/15/25 16:31	4/14/25	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Akinsanya Karen	NY	O	P of R,D	2	M.d	472	14.12	33		16	D
4/15/25 16:31	4/14/25	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Akinsanya Karen	NY	O	P of R,D	2	S.d	-472	14.12	-33		16	D
4/15/25 16:30	4/13/25	CELU	Celularity Inc	DE	Health	Drug	Pharmaceutical Preparations	Brigido Stephen	NJ	O	P,Functi	2	M.d	0	0.00	11		9	D
4/15/25 16:30	4/13/25	CELU	Celularity Inc	DE	Health	Drug	Pharmaceutical Preparations	Hariri Robert J	NJ	DO	CEO	1	M.d	0	0.00	3	19	20	D
4/15/25 16:30	4/13/25	CELU	Celularity Inc	DE	Health	Drug	Pharmaceutical Preparations	Haines John R	NJ	O	Senior E	2	M.d	0	0.00	22	289	29	D
4/15/25 16:30	4/13/25	CELU	Celularity Inc	DE	Health	Drug	Pharmaceutical Preparations	Beers David C	NJ	O	CFO	2	M.d	0	0.00	14	289	18	D
4/15/25 14:02	4/10/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Irrevocable Larson Family Investment Trust	TX	T		1	P.m	94	1.07	88	3	3,558	D
4/15/25 12:50	4/2/25	NBY	Novabay Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Poplar Point Capital Partners LP	CA	T		7	P.m	314	0.6251	502	97	1,020	D
4/15/25 07:59	3/24/25	TXMD	Therapeuticsmd, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Thompson Tommy G	FL	D		6	M.d	2,470	131.22	19	57	52	D
4/15/25 07:59	3/24/25	TXMD	Therapeuticsmd, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Thompson Tommy G	FL	D		6	S.d	-2,470	131.22	-19		52	D
4/15/25 07:59	4/14/25	TXMD	Therapeuticsmd, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Walker Marlan D	FL	O	CEO	3	P.dm	2	0.2242	11	18	74	D
4/14/25 19:26	4/11/25	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Foehr Matthew W	CA	D		1	M.d	166	8.00	21	19	132	D
4/14/25 18:57	4/10/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shah Gaurav	NJ	DO	CEO	2	P	274	7.55	36	3	1,199	D
4/14/25 18:23	4/11/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Cline Christopher R.	CA	O	CFO	2	S.d	-105	20.06	-5		90	D
4/14/25 17:58	4/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		6	M.d	502	38.05	13		0	D
4/14/25 17:58	4/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		6	S.d	-502	38.05	-13	-100	0	D
4/14/25 17:17	4/11/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Lurker Nancy		D		1	M.d	0	0.00	6		5	D
4/14/25 16:17	4/14/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	3	S	-77	63.94	-1		82	D
4/14/25 16:13	4/10/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Cornelissen Bart Jan	CA	O	SVP,CFO	1	S	-30	8.06	-4		61	D
4/11/25 21:57	4/9/25	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Adar1 Capital Management, LLC	TX	T		1	P.d	9,465	10.13	934	21	5,391	I
4/11/25 21:45	4/9/25	OSTX	Os Therapies Inc	DE	Health	Drug	Pharmaceutical Preparations	Auerbach Shalom	NY	T		2	S.m	-366	2.29	-160		2,770	I
4/11/25 18:20	4/9/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Anzalone Christopher Richard	CA	DO	CEO	4	S.dm	-9,908	12.50	-793		4,062	D
4/11/25 18:00	4/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	4	S	-3,970	43.27	-92		686	D
4/11/25 17:29	4/9/25	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Springer Timothy A	MA	DT		2	P.m	2,894	12.11	239	3	9,631	M
4/11/25 17:22	4/1/25	PCSA	Processa Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lin Patrick	MD	O	Chief Bu	1	M	0	0.00	14	21	82	D
4/11/25 17:22	4/9/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Venrock Healthcare Capital Partners Iii, L.P.	NY	T		5	P.m	4,730	9.77	484	5	9,452	I
4/11/25 17:20	4/1/25	PCSA	Processa Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Guy Wendy	MD	O	Chief Ad	1	M	0	0.00	14	72	35	D
4/11/25 17:17	4/1/25	PCSA	Processa Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bigora Sian	MD	O	Chief De	1	M	0	0.00	15	60	40	D
4/11/25 17:16	4/1/25	PCSA	Processa Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young David	MD	DO	P Resear	1	M	0	0.00	17	7	278	D
4/11/25 13:23	4/10/25	GOVX	Geovax Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Spencer John N Jr	GA	D		1	P	10	0.9800	10	713	11	D
4/10/25 19:06	4/9/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Jenkins George M	PA	D		1	P	101	20.20	5	3	197	M
4/10/25 19:02	4/8/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kocak Ron	CA	O	VP Contr	1	P.m	10	0.7948	13		13	D
4/10/25 17:07	4/10/25	OPK	Opko Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Frost Phillip Md Et Al	FL	DOT	CEO,CB	6	P.d	1,237	1.61	767	0	247,698	I
4/10/25 16:15	4/8/25	ACUT	Accustem Sciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cerrone Gabriele M	NY	DT		2	P.m	104	0.5428	191	4	4,911	I
4/10/25 16:07	4/9/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Kinnari	NJ	O	See Rema	2	P	163	6.02	27	5	576	I
4/10/25 16:02	4/8/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fouse Jacqualyn A	MA	D		2	M.d	194	8.29	23	19	149	D
4/10/25 16:02	4/10/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fouse Jacqualyn A	MA	D		2	S.d	-194	8.29	-23		149	D
4/10/25 16:01	4/10/25	GOVX	Geovax Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sharkey John W.	GA	O	VP,Busin	1	P	6	0.9900	6	999%	6	D
4/10/25 08:39	4/8/25	MBX	Mbx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pescovitz Ora H.	IN	D		1	P	45	5.89	8	46	24	D
4/9/25 21:30	4/8/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Marton Laurence	CA	D		1	P	10	0.8480	12	36	46	D
4/9/25 16:44	4/7/25	XOMA	Xoma Royalty Corp		Health	Drug	Pharmaceutical Preparations	Sitko Bradley	CA	O	Chief In	3	P	174	23.63	7	53	21	D
4/9/25 16:44	4/7/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Patel Sanj K	X0	DO	CB,CEO	3	M.d	0	0.00	29	17	206	D
4/9/25 16:43	4/7/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Paolini John F.	X0	O	CHIEF ME	3	M.d	0	0.00	8	15	57	D
4/9/25 16:41	4/7/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Megna Michael R	X0	O	CHIEF AC	5	M.d	304	10.95	28	576	33	D
4/9/25 16:25	4/7/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	3	S.d	-409	20.47	-20		330	I
4/9/25 07:25	3/1/25	AMRN	Amarin Corp Plcuk	X0	Health	Drug	Pharmaceutical Preparations	Fishman Peter L.	NJ	O	SVP,CFO	1	M.dm	0	0.00	5	7	77	D
4/8/25 21:52	4/4/25	VREO	Vireo Growth Inc.	A1	Health	Drug	Pharmaceutical Preparations	Chicago Atlantic Credit Opportunities, LLC	IL	T		7	P.dm	20,231	0.6210	32,579	35	126,744	D
4/8/25 21:36	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Garnett Keithly	CA	DO	CFO	1	S.ad	-164	24.85	-7		321	I
4/8/25 21:36	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Heshmatpour Amir F	CA	D		1	S.ad	-956	24.85	-38		6,802	I
4/8/25 21:36	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Walters Patrick	CA	O	COO	1	S.ad	-294	24.85	-12		876	I
4/8/25 21:35	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chiang Ming-Fu (Alan)	CA	D		1	S.ad	-1,434	24.85	-58		2,180	M
4/8/25 21:35	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chen Thomas C		DOT	CEO	1	S.ad	-975	24.85	-39		4,843	I
4/8/25 21:30	4/4/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hung David	NY	DOT	P,CEO	1	P.m	820	1.64	500	1	58,781	D
4/8/25 20:22	4/7/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quisel John D	MA	DO	CEO	2	M.d	311	24.76	13	8	162	D
4/8/25 19:24	4/4/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Raab Michael	MA	DO	P,CEO	5	M.d	585	3.95	148	10	1,661	D
4/8/25 19:24	4/4/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Raab Michael	MA	DO	P,CEO	5	S.d	-585	3.95	-148		1,661	D
4/8/25 19:05	3/31/25	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rouan Sarah Kathryn	CA	D		2	P	60	24.15	2		1	D
4/8/25 17:32	4/4/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saccomano Nicholas A	CO	DO	P,CEO	1	S.m	-3	2.94	-1		4	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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