Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
11/7/25 21:00	11/7/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	6	S.dm	-58,037	15.89	-3,653		1,654	D
11/7/25 18:03	11/6/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Daniels Ronald J	CA	D		1	S.d	-3,889	63.72	-61		17	D
11/7/25 17:13	11/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Birchler Brian	CA	O	EVP,Corp	2	S.dm	-2,333	73.15	-32		57	D
11/7/25 17:12	11/5/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Geary Richard S	CA	O	EVP,Chie	5	S.dm	-13,859	71.02	-195		80	D
11/7/25 17:10	11/5/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	3	S.d	-4,716	78.60	-60		5	D
11/7/25 16:58	11/6/25	EVOK	Evoke Pharma Inc	DE	Health	Drug	Pharmaceutical Preparations	Klein Roger M.	MA	T		1	S	-96	10.65	-9		154	I
11/7/25 16:30	11/5/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	3	S.d	-2,609	26.98	-97		250	D
11/7/25 16:30	11/6/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	23	S.dm	-76,839	426.88	-180		644	D
11/7/25 16:23	11/6/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Tupper Colleen	MA	O	EVP,CFO	1	S	-1,216	40.53	-30		127	D
11/7/25 16:20	11/7/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Loomis David K	CT	O	Chief Ac	1	S	-2	9.89	0		32	D
11/7/25 16:20	11/5/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bate Kenneth	PA	D		2	S.d	-11,679	439.49	-27		3	D
11/7/25 16:09	11/5/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Lewis Joel	GA	DO	P,CEO	3	S.dm	-186	6.20	-30		835	D
11/7/25 16:07	11/5/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Callicutt Jack W	GA	O	CFO	3	S.dm	-256	6.14	-42		15	D
11/7/25 16:01	11/5/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Saroj Namrata	MA	O	Chief Bu	1	S	-278	10.74	-26		174	D
11/6/25 19:43	10/27/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Evnin Luke	MA	D		3	S.m	-728	1.39	-522		4,133	I
11/6/25 19:41	11/4/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mpm Bioventures 2014, L.P.	MA	T		3	S.m	-1,134	1.39	-814		6,443	I
11/6/25 19:40	11/4/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gadicke Ansbert	MA	T		3	S.m	-1,134	1.39	-814		6,443	I
11/6/25 18:12	11/4/25	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Eizen Joshua M	CA	O	See Rema	1	S	-3	1.14	-3		177	D
11/6/25 18:11	11/4/25	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Prior Stephen David	CA	O	Chief St	1	S	-1	1.14	-1		66	D
11/6/25 17:46	9/9/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	Bendheim Jack	NJ	DOT	P,CEO	7	S.dm	-4,152	40.67	-102		91	I
11/6/25 17:01	11/4/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Kaye Jack	P7	D		1	S.d	-1,178	30.34	-39		20	D
11/6/25 16:40	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	8	S.dm	-469	6.19	-76	-100	0	D
11/6/25 16:05	11/4/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Calvin Sandra	CA	O	SVP,Chie	1	S.d	-2,416	36.00	-67		49	D
11/6/25 16:00	11/5/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		17	S	-1,715,814	847.32	-2,025		95,630	D
11/6/25 12:21	11/3/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Paterson Dan	MA	DO	P,CEO	2	S	-36	9.77	-4		442	D
11/5/25 21:15	11/3/25	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Turtle Cameron	MA	DO	CEO	1	S	-1,050	23.33	-45		702	D
11/5/25 19:59	11/3/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	3	S.d	-1,143	76.22	-15		10	D
11/5/25 19:57	11/3/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Belanoff Joseph K	CA	DO	CEO	3	S.m	-9,207	76.73	-120		2,821	I
11/5/25 19:56	11/3/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	3	S.d	-4,591	76.51	-60		118	D
11/5/25 19:01	11/3/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tabuteau Herriot	NY	DOT	CEO	3	S.dm	-34,596	127.09	-272		7,352	D
11/5/25 18:57	8/19/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	2	S.m	-223	20.86	-11		105	D
11/5/25 18:24	11/3/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		3	S.d	-598	19.94	-30		100	D
11/5/25 18:24	11/3/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vairavan Latha	CA	O	SVP CFO	1	S	-2	24.72	0	0	65	D
11/5/25 18:23	11/3/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watanabe Todd	CA	DO	See Rema	4	S.m	-2,349	22.02	-107		1,125	D
11/5/25 18:23	11/3/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Matsuda Masaru	CA	O	See Rema	2	S	-762	17.58	-43		161	D
11/5/25 18:17	11/4/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quigley Jill M.	CA	D		1	S.d	-441	18.00	-25	-100	0	D
11/5/25 18:00	11/5/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yap Kim Choy	N8	T		6	S.d	-770	1.90	-405		468	D
11/5/25 17:22	11/3/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Kozarich John W	FL	D		3	S	-249	177.58	-1		46	D
11/5/25 17:00	9/2/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pizzuti Dana	CA	O	Chief Me	5	S.d	-1,685	32.73	-51		96	D
11/5/25 16:31	11/4/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Edgemond James	MD	O	CFO,TREA	1	S.d	-9,158	436.09	-21		8	D
11/5/25 16:30	11/3/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Breedlove Robert Charles	NJ	O	Principa	2	S	-13	12.84	-1		55	D
11/5/25 16:20	11/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticho Barry	MA	O	Chief Me	4	S	-439	22.44	-20		24	D
11/5/25 16:20	11/3/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Petersen Floyd F.	CA	D		3	S	-42	27.82	-2		77	D
11/5/25 16:08	11/3/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Smith Michael Alexander	NJ	O	GC	2	S.d	-8,478	164.94	-51		55	D
11/5/25 16:05	11/4/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Clark David Michael	NJ	O	Chief Pe	1	S	-244	9.51	-26		323	D
11/5/25 09:57	11/3/25	MTSR	Metsera, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fmr LLC	MA	TH	See Rema	2	S	-21	46.56	0	0	4,325	I
11/4/25 19:23	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	6	S.d	-658	53.07	-12		141	D
11/4/25 16:36	10/31/25	KNSA	Kiniksa Pharmaceuticals International, Plc		Health	Drug	Pharmaceutical Preparations	Paolini John F.	X0	O	CHIEF ME	1	S.d	-3,066	37.14	-83		61	D
11/4/25 16:30	11/3/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	10	S.dm	-92,456	422.42	-219		3	I
11/4/25 16:13	11/3/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	3	S.d	-73	34.20	-2		17	D
11/4/25 16:05	10/31/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Coughlin Timothy	CA	D		1	S.d	-631	35.03	-18		56	D
11/4/25 16:05	10/31/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Heerma Peter	CA	O	Chief Co	2	S	-276	33.39	-8		125	D
11/4/25 16:02	11/3/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Williams David Michael	NJ	O	EVP,Chie	1	S	-720	83.59	-9		25	D
11/3/25 20:14	10/30/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Wender Joseph H	CA	D		4	S.m	-6,397	63.47	-101		109	I
11/3/25 20:14	10/31/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Loscalzo Joseph	CA	D		2	S.d	-2,164	67.63	-32		36	D
11/3/25 19:14	11/3/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Van Houte Hans	CA	O	CFO	2	S.d	-119	12.64	-9		44	D
11/3/25 18:00	10/30/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kua Khai Loon	N8	T		4	S.m	-1,251	3.09	-404		385	D
11/3/25 18:00	10/30/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ong Yee Lung	N8	T		3	S	-1,302	3.22	-404		269	D
11/3/25 17:25	6/9/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nussdorf Glenn H	NY	DT		1	S.m	-81	3.55	-23	0	12,249	I
11/3/25 16:46	10/30/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jaen Juan C.	CA	O	P	2	S.m	-2,098	20.74	-101		1,459	I
11/3/25 16:37	11/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Hopkinson Craig C.	MA	O	EVP R,D,	2	S.d	-557	30.96	-18		74	D
11/3/25 16:30	10/30/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	5	S.d	-5,251	109.46	-48		9	D
11/3/25 16:10	10/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gheuens Sarah	MA	O	Chief Me	2	S.d	-154	43.91	-4		62	D
10/31/25 16:38	10/29/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCormick Frank	CA	D		3	S.d	-17,247	62.94	-274		963	I
10/31/25 16:31	8/25/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	3	S.d	-1,042	86.87	-12		48	D
10/31/25 16:30	10/30/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Miller Deborah Ann	MA	O	GC	3	S.dm	-5,264	96.05	-55		49	D
10/31/25 16:09	10/29/25	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	Poon Christine A	NY	D		1	S.d	-4,253	654.27	-7		5	D
10/31/25 15:30	10/29/25	SYBX	Synlogic, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dooley Mary Beth	MA	O	See Rema	1	S	0	1.81	0		13	D
10/30/25 20:00	10/28/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meyer Andrew Hollman	CA	O	Chief Bu	1	S.d	-501	30.06	-17		82	D
10/30/25 18:02	10/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ring Christine	CA	O	GC	1	S.d	-47	12.80	-4		51	D
10/30/25 18:01	10/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hansen Gwenn	CA	O	Chief Sc	1	S.d	-52	12.80	-4		77	D
10/30/25 16:47	10/28/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Ragosa Mark	X0	O	CFO	1	S.d	-4	41.00	0	0	31	D
10/30/25 16:45	10/28/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Dube Eric M	CA	DO	CEO	1	S.dm	-3,638	30.32	-120		419	D
10/30/25 16:37	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	6	S.d	-26,604	403.09	-66		37	D
10/30/25 16:25	9/2/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	6	S	-1,574	52.48	-30		387	D
10/29/25 16:31	10/27/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shair Matthew	MA	D		1	S.m	-6,015	100.26	-60		1,586	M
10/29/25 16:30	10/27/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	3	S.dm	-841	27.23	-31		176	D
10/29/25 16:30	10/27/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Boyle Dana	NC	O	Chief Ac	3	S	-62	23.85	-3		187	D
10/29/25 16:24	10/27/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hattersley Gary	NY	O	Chief Sc	1	S.d	-502	5.02	-100	-100	0	D
10/29/25 08:54	10/28/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goeltz II Robert C.	CA	O	CFO	1	S	-100	20.00	-5		92	D
10/28/25 21:05	10/24/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ra Capital Management, L.P.	MA	DT		1	S.m	-14,763	39.51	-374		209	I
10/28/25 19:51	10/28/25	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mancini Marianna	CA	O	COO	1	S	-216	35.00	-6		382	D
10/28/25 19:49	10/27/25	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rowland Charles A Jr	CA	D		1	S.d	-2,134	35.57	-60		30	D
10/28/25 19:48	10/28/25	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lian Brian	CA	DO	P,CEO	1	S	-1,365	35.01	-39		2,419	D
10/28/25 19:47	10/28/25	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zante Greg	CA	O	CFO	1	S	-216	35.00	-6		174	D
10/28/25 17:00	10/24/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szot Matthew K	FL	O	CFO	6	S.m	-328	14.03	-23		31	D
10/28/25 17:00	10/24/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pham Quang X	FL	DOT	CEO,CB	6	S.m	-312	14.04	-22		413	D
10/28/25 16:10	10/27/25	MRSN	Mersana Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bala Mohan	MA	O	SVP,Chie	1	S.d	-1	9.90	0		3	D
10/27/25 19:56	10/27/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	3	S.d	-515	22.22	-23		206	D
10/27/25 17:59	10/27/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Wierenga Wendell	CA	D		1	S.d	-257	58.68	-4		32	D
10/27/25 17:19	10/23/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		2	S	-2,420	1.61	-1,500		5,975	I
10/27/25 16:23	10/24/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohen Yuval	MA	DO	CEO	1	S.dm	-471	17.05	-28		138	D
10/27/25 16:22	10/24/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moran Sean F.	MA	O	CFO	1	S.d	-221	17.02	-13		73	D
10/27/25 16:15	10/23/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Third Rock Ventures Iv, L.P.	MA	T		6	S.m	-26,351	7.59	-3,473		15,759	D
10/24/25 20:18	10/22/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	10X Fund, L.P.	GA	T		1	S	-247	4.94	-50		5,872	D
10/24/25 20:00	10/23/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Iwicki Mark T	MA	D		1	S	-125	0.8100	-155		104	D
10/24/25 20:00	10/22/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Reumuth Mary	MA	O	CFO	1	S.m	-28	0.8297	-33		29	D
10/24/25 20:00	10/22/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bazemore Todd	MA	D		1	S	-40	0.8300	-48		36	D
10/24/25 20:00	10/22/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brazzell Romulus K	MA	O	SEE REMA	1	S	-39	0.8300	-47		36	D
10/24/25 20:00	10/22/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kharabi Darius	MA	O	CHIEF BU	1	S	-17	0.8300	-21		42	D
10/24/25 16:56	10/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	5	S.d	-439	45.22	-10		39	D
10/24/25 16:30	10/23/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McGrath Lynne Fahey	GA	D		1	S	0	2.30	0		0	D
10/24/25 16:01	10/22/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ai Dmi LLC	NY	T		1	S	-59,873	80.47	-744		2,814	D
10/23/25 18:00	10/21/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fitters Diversified Berhad	N8	T		5	S	-1,777	4.23	-420		557	D
10/23/25 16:20	10/21/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sullivan Timothy Eugene	MA	O	CFO	2	S.d	-1,470	27.89	-53		171	D
10/22/25 19:20	10/20/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	5	S.m	-771	20.56	-38		940	I
10/22/25 18:57	10/20/25	RANI	Rani Therapeutics Holdings, Inc.	CA	Health	Drug	Pharmaceutical Preparations	South Cone Investments Limited Partnership	F3	T		1	S.m	-15,711	2.65	-5,923		2,379	I
10/22/25 17:39	8/26/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cloonan Michael	MA	DO	P,CEO	5	S.dm	-6,328	31.64	-200		547	D
10/22/25 17:09	10/20/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Patel Sanj K	X0	DO	CB,CEO	1	S.dm	-10,024	38.86	-258		222	D
10/22/25 17:06	10/20/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Megna Michael R	X0	O	CHIEF AC	2	S.d	-2,346	38.15	-61		38	D
10/21/25 18:13	10/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	6	S.m	-763	20.35	-38		929	I
10/21/25 17:12	10/21/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Booth Bruce	MA	D		5	S.m	-22,086	31.62	-698		3,615	I
10/21/25 16:54	10/20/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Altmeyer Anne	MA	D		1	S.d	-22	20.50	-1		6	D
10/20/25 20:00	9/12/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		16	S.m	-816	1.77	-460		4,483	I
10/20/25 19:13	10/17/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Reed John C	NJ	O	EVP,Inno	1	S.d	-4,186	192.71	-22		11	D
10/20/25 18:58	10/16/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	Cooperatieve Gilde Healthcare IV U.A.	P7	T		3	S.m	-5,141	1.48	-3,473		5,294	D
10/17/25 17:53	10/15/25	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Pontifax Management 4 G.P. (2015) Ltd.	L3	T		1	S	-84,975	17.75	-4,787	-100	11	I
10/17/25 16:41	10/15/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		4	S.m	-16,464	75.51	-218		1,064	I
10/17/25 16:32	8/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	3	S.d	-6,618	81.71	-81		249	D
10/17/25 16:31	10/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	3	S.dm	-2,467	88.12	-28		66	D
10/17/25 16:31	10/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	4	S.dm	-7,694	86.19	-89		62	D
10/17/25 16:28	10/16/25	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dugan Margaret	NY	O	Chief Me	1	S	-29	21.07	-1		25	D
10/17/25 16:27	10/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Teresa	CA	O	CHRO	3	S.d	-2,090	46.44	-45		97	D
10/17/25 16:15	10/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	4	S	-910	26.01	-35		204	D
10/17/25 16:10	10/16/25	PRAX	Praxis Precision Medicines, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Adage Capital Management, L.P.	MA	T		1	S	-33,198	105.76	-314		4,422	I
10/17/25 14:01	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jung Cassie	NJ	O	COO	2	S.d	-785	6.05	-130		285	D
10/17/25 14:01	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kraus Carl N	NJ	O	Chief Me	1	S	-142	7.00	-20		282	D
10/17/25 14:00	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Boyd Peter E.	NJ	O	See Rema	3	S	-213	6.07	-35		288	D
10/16/25 20:16	10/16/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	4	S.dm	-2,823	62.54	-45		37	I
10/16/25 20:16	10/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Parshall B Lynne	CA	D		2	S	-1,377	55.08	-25		66	D
10/16/25 20:16	10/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	2	S.dm	-724	69.41	-10		17	D
10/16/25 16:41	10/15/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	2	S.dm	-1,139	18.08	-63		203	D
10/16/25 16:35	10/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	6	S.dm	-7,263	36.18	-201		44	D
10/16/25 16:30	10/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	3	S	-552	21.66	-26		427	D
10/16/25 16:30	9/4/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ceesay Abraham	MA	DO	CEO	3	S	-2,357	26.28	-90		722	D
10/16/25 16:21	10/7/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	Glessner Coleen	MD	O	EVP,Qual	1	S	-306	10.00	-31		144	D
10/16/25 16:15	10/16/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seshadri Vishwas	OH	DO	CEO	2	S.m	-236	5.31	-45		1,190	D
10/16/25 16:13	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	4	S.dm	-1,209	20.85	-58		111	D
10/16/25 16:01	10/14/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Militello John	NJ	O	See Rema	3	S.m	-139	3.76	-37		67	D
10/15/25 20:12	10/10/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunlop A. Sinclair	MA	D		3	S	-2,153	23.08	-93		223	M
10/15/25 19:04	10/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levy Adam Scott	PA	O	CFO,Secr	1	S	-452	42.01	-11		117	D
10/15/25 19:04	10/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Congleton Jon	PA	DO	CEO	1	S	-644	42.67	-15		831	D
10/15/25 19:04	10/15/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	2	S	-855	39.35	-22		82	D
10/15/25 18:31	10/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		2	S.d	-352	80.00	-4	-100	0	D
10/15/25 18:00	10/13/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazumdar Claire	MA	DO	CEO	1	S.dm	-467	18.88	-25		310	D
10/15/25 16:36	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	2	S.d	-214	24.08	-9		595	D
10/15/25 16:34	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	3	S.d	-829	25.30	-33		358	D
10/15/25 16:34	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	2	S.d	-2,138	28.29	-76		155	D
10/15/25 16:32	10/6/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parkman Healthcare Partners LLC	CT	T		2	S	-10	19.14	-1		1	I
10/15/25 16:31	9/2/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	4	S.dm	-13,848	106.18	-130		2,752	D
10/15/25 16:30	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Krepp Sarah	NC	O	Chief Hu	2	S	-46	24.03	-2		143	D
10/15/25 13:24	10/15/25	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Adar1 Capital Management, LLC	TX	T		1	S	-95,659	17.75	-5,389	-100	0	I
10/14/25 20:11	10/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	2	S.dm	-2,994	48.45	-62		526	D
10/14/25 19:49	10/13/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	2	S	-75	94.26	-1		76	D
10/14/25 16:31	10/9/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Bunn Paul A.	MA	D		1	S	-75	9.06	-8		8	D
10/14/25 16:01	10/10/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Waddill William D.	CA	D		3	S.d	-1,473	73.67	-20		9	D
10/14/25 12:15	10/13/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Horn Howard	CA	O	CFO	1	S	-250	31.51	-8		98	D
10/10/25 19:17	10/10/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McFarlane Neil F.	FL	DO	P,CEO	1	S.d	-211	10.82	-20		222	D
10/10/25 17:40	9/4/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	3	S.m	-9,836	52.84	-186		5,857	I
10/10/25 17:33	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	12	S.dm	-12,663	47.59	-266		2,212	D
10/10/25 17:23	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Raben David	MA	O	Chief Me	1	S.d	-406	18.45	-22		35	D
10/10/25 17:22	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	2	S.dm	-670	18.21	-37		145	D
10/10/25 16:56	10/8/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	3	S.d	-10,305	325.19	-32		252	D
10/10/25 16:30	10/8/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	D		7	S.dm	-1,584	2.40	-661		124	I
10/10/25 16:21	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Newhall Charles W III	MD	D		4	S	-1,539	49.65	-31		134	D
10/10/25 16:18	10/8/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		3	S.d	-24	40.33	-1		18	D
10/10/25 16:12	10/8/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	MA	D		7	S.dm	-4,394	27.18	-162		177	D
10/10/25 16:01	10/8/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Anderman Todd	MA	O	GC	1	S	-137	12.34	-11		88	D
10/9/25 18:58	9/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	3	S.d	-1,152	45.08	-26		167	D
10/9/25 17:21	10/7/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	2	S	-269	20.17	-13		283	I
10/9/25 16:22	8/19/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peters Malte	NY	DO	CEO	1	S	-21	0.8217	-25		54	D
10/9/25 13:37	10/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Degnan Chris	NJ	O	CFO	1	S.d	-37	16.85	-2		2	D
10/8/25 19:48	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hunter Heather	MI	O	SVP,COO	1	S	-3	1.19	-3		135	D
10/8/25 19:08	10/6/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jarrett Jennifer	CA	O	COO	1	S.dm	-750	14.92	-50		214	D
10/8/25 18:37	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	6	S.dm	-13,812	63.94	-216		57	D
10/8/25 18:36	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	2	S.d	-12,325	60.34	-204		180	D
10/8/25 18:36	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	5	S.d	-3,837	62.27	-62		35	D
10/8/25 17:37	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	1	S.d	-160	14.52	-11		48	D
10/8/25 17:35	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chacko Jacob	CA	DO	P,CEO	3	S.m	-2,865	11.46	-250		656	D
10/8/25 16:16	10/7/25	CARM	Carisma Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klichinsky Michael	PA	O	Chief Sc	2	S.dm	-139	0.2565	-541	-100	0	D
10/8/25 16:10	10/6/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		3	S.m	-42	3.56	-12		1,046	D
10/7/25 16:26	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Allan Jonathan	MA	O	GC,Corp	4	S.dm	-932	19.61	-48		24	D
10/7/25 16:11	10/3/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mosbrooker Eric	CA	O	Chief Co	2	S.d	-607	46.23	-13		55	D
10/6/25 17:13	10/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Kaiser Peter	MA	O	Chief De	2	S	-143	11.27	-13		204	D
10/6/25 17:10	10/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Heier Jeffrey S.	MA	O	Chief Sc	2	S	-153	11.27	-14		260	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Lee Kevin	X0	DO	CEO	1	S.m	-46	8.41	-5		475	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Skynner Michael	X0	O	CTO	1	S.m	-15	8.41	-2		118	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Milnes Alistair	X0	O	COO	1	S.m	-18	8.40	-2		93	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Hannay Michael Charles Ferguson	X0	O	CHIEF PR	1	S.m	-6	8.40	-1		53	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Young Alethia	X0	O	CFO	1	S	-4	8.51	0		45	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Thompson Travis Alvin	X0	O	Chief Ac	1	S.m	-3	8.40	0		31	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Swanton Robert Charles	X0	D		1	S	-1	8.55	0		15	D
10/6/25 15:15	10/2/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Edwards Larry Todd	CA	O	See Rema	1	S	-90	20.04	-5		179	D
10/3/25 21:58	10/2/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	Plassche Douglas	NJ	O	EVP Oper	1	S	-499	0.6240	-800		3,500	D
10/3/25 21:27	9/2/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	Cozadd Bruce C	L2	D		2	S.m	-1,525	132.63	-12		430	D
10/3/25 18:15	10/1/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hamilton James C	CA	O	Chief Me	4	S.m	-1,725	28.75	-60		262	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Poulton Jeffrey V.	MA	O	EVP,CFO	2	S	-2,758	452.50	-6		54	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Greenstreet Yvonne	MA	DO	CEO	2	S	-7,197	452.58	-16		66	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Tanguler Tolga	MA	O	EVP,Chie	3	S	-2,826	450.28	-6		29	D
10/3/25 17:13	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Fitzgerald Kevin Joseph	MA	O	CSO,EVP,	2	S	-1,736	452.49	-4		26	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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