Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
6/18/25 21:28	6/16/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	14	P.d	4,153	3.81	1,090	21	6,267	D
6/18/25 21:16	6/16/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	M.dm	11,513	61.62	187	67	464	D
6/18/25 21:16	6/16/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	S.dm	-11,513	61.62	-187		464	D
6/18/25 21:01	6/16/25	MBRX	Moleculin Biotech, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	0	0.00	3	4	70	D
6/18/25 18:45	6/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S	-50	1.12	-44		2,795	D
6/18/25 18:26	6/16/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	7	38	S.dm	-59,137	55.91	-1,058		4,446	D
6/18/25 18:22	6/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	22	S.dm	-1,890	17.19	-110		2,323	I
6/18/25 18:04	6/17/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-19	7.49	-3		154	D
6/18/25 18:02	6/17/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	9	S.d	-1,797	23.59	-76		131	D
6/18/25 17:18	6/16/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	7	S.d	-1,322	40.99	-32		669	D
6/18/25 17:12	6/16/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	251	7.94	32		0	D
6/18/25 17:12	6/16/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-251	7.94	-32	-100	0	D
6/18/25 17:12	6/16/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	6	18	S.dm	-60,872	13.75	-4,428		67,813	D
6/18/25 17:00	6/16/25	RGLS	Regulus Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.dm	156	8.51	18	20	111	D
6/18/25 16:57	6/16/25	XLO	Xilio Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.m	73	0.6846	106	43	351	D
6/18/25 16:50	6/16/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	6	19	P.d	5,142	5.71	901	14	7,558	I
6/18/25 16:39	6/16/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	12	56	M.dm	19,914	17.90	1,113		586	D
6/18/25 16:39	6/16/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	12	56	S.dm	-19,914	17.90	-1,113		586	D
6/18/25 16:32	5/13/24	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.adm	755	12.35	61	35	238	D
6/18/25 16:31	6/16/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	7	33	M.dm	37,059	6.66	5,561	21	32,537	D
6/18/25 16:31	6/16/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	7	33	S.dm	-37,059	6.66	-5,561		32,537	D
6/18/25 16:16	6/16/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	8	35	S.dm	-54,234	58.20	-932		1,341	M
6/18/25 16:16	6/16/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	8	35	M.dm	54,234	58.20	932	228	1,341	M
6/18/25 16:15	6/16/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S	-256	10.04	-26		461	D
6/18/25 16:11	6/16/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	10	15	S.dm	-2,699	3.76	-718		4,785	D
6/18/25 16:05	6/18/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	9	P.dm	2,180	1.73	1,257	2	59,664	D
6/18/25 09:11	6/17/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	89	2.21	40	999%	43	D
6/18/25 08:49	6/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-142	7.98	-18		1,374	D
6/17/25 21:30	6/13/25	VREO	Vireo Growth Inc.	A1	Health	Drug	Pharmaceutical Preparations	2	13	P.dm	371	0.3591	1,034	0	238,302	I
6/17/25 19:55	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	S	-312	3.40	-92		364	D
6/17/25 18:33	6/15/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	7	7	M.d	0	0.00	44	54	124	D
6/17/25 17:53	6/16/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	3	9	M.d	0	0.00	167	31	710	D
6/17/25 17:45	5/28/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	16	S.m	-1,359	14.62	-93		10,831	D
6/17/25 16:44	6/13/25	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	1	2	P.m	35,871	5.65	6,353	24	32,792	I
6/17/25 16:35	6/13/25	PTN	Palatin Technologies Inc	NJ	Health	Drug	Pharmaceutical Preparations	4	4	P.d	454,010	4,399.3	103	3	3,676	D
6/17/25 16:31	6/16/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	14	M.d	9,179	49.25	186	107	360	D
6/17/25 16:31	6/16/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	14	S.d	-9,179	49.25	-186		360	D
6/17/25 16:27	6/17/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	8	28	M.d	3,865	26.07	148	23	796	D
6/17/25 16:27	6/17/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	8	28	S.d	-3,865	26.07	-148		796	D
6/17/25 16:16	6/13/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	M.d	194	7.09	27	21	157	D
6/17/25 16:11	6/13/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	6	6	P.d	31	2.19	14	2	821	D
6/17/25 16:11	6/13/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.dm	-220	0.7174	-307		1,681	D
6/17/25 16:11	6/13/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.dm	220	0.7174	307	22	1,681	D
6/16/25 21:10	6/13/25	VNDA	Vanda Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-161	4.34	-37		2,423	D
6/16/25 20:06	6/12/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	P.m	15,855	9.83	1,613	15	12,236	I
6/16/25 19:35	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	7	7	S.d	-214	9.40	-23		209	D
6/16/25 19:03	6/14/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	7	M.dm	0	0.00	6	1	502	D
6/16/25 18:05	6/13/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.m	59	3.73	16	30	68	D
6/16/25 17:47	6/13/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-369	36.94	-10		229	D
6/16/25 17:24	6/13/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	6	S	-426	62.75	-7		1,007	D
6/16/25 17:19	6/13/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	2	4	M.d	2,645	13.13	202	2	10,939	D
6/16/25 17:00	6/13/25	IMUX	Immunic, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	P.dm	247	0.7358	336	53	966	D
6/16/25 16:56	6/10/25	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	P.m	4,222	16.76	252	4	6,341	I
6/16/25 16:48	6/12/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	3,588	13.44	267	24	1,402	D
6/16/25 16:48	6/12/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-3,588	13.44	-267		1,402	D
6/16/25 16:42	6/13/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.m	-1,804	10.03	-180		1,085	D
6/16/25 16:26	6/13/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	1	1	P	109	4.38	25	1	1,736	D
6/16/25 16:03	6/12/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	13	14	S.d	-7,155	13.76	-520		4,482	D
6/16/25 16:03	6/12/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	11	M.d	5,223	13.19	396	4	10,100	D
6/16/25 16:03	6/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	11	S.d	-5,223	13.19	-396		10,100	D
6/16/25 15:40	5/28/25	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.m	-3,111	1.13	-2,751		4,742	I
6/16/25 10:22	6/13/25	ACUT	Accustem Sciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	P.m	124	0.5403	230	4	6,502	I
6/16/25 08:48	6/12/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	4	26	M.d	45,375	216.07	210		69	D
6/16/25 08:48	6/12/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	4	26	S.d	-45,375	216.07	-210		69	D
6/13/25 20:00	6/13/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	1	1	S	-209	6.95	-30		283	D
6/13/25 19:57	6/13/25	LTRN	Lantern Pharma Inc.	TX	Health	Drug	Pharmaceutical Preparations	2	6	S.m	-1,001	3.17	-316		2,355	I
6/13/25 19:38	6/12/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.m	-65	10.01	-7		104	D
6/13/25 19:00	6/11/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	6	11	S.dm	-1,562	5.03	-311		1,312	D
6/13/25 17:05	6/11/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	P.m	28	1.77	16	2	1,034	I
6/13/25 16:18	6/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	9	S.dm	-568	11.81	-48		3,780	D
6/13/25 08:00	6/12/25	SLS	Sellas Life Sciences Group, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	P	85	1.69	50	120	92	D
6/12/25 18:34	6/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	27	S.dm	-20,432	40.51	-504		2,442	D
6/12/25 17:51	6/10/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	5	6	S.d	-1,569	90.61	-17		301	D
6/12/25 17:00	6/10/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.dm	-13,725	18.01	-762		4,591	D
6/12/25 16:50	6/10/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	19	M.dm	13,461	34.92	385		381	D
6/12/25 16:50	6/10/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	19	S.dm	-13,461	34.92	-385		381	D
6/11/25 20:34	6/9/25	ERNA	Ernexa Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	P.d	2,616	0.0684	38,262	999%	41,660	D
6/11/25 18:25	6/6/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	1	1	M.d	699	2.16	323	45	1,046	D
6/11/25 17:40	6/9/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	3	4	M.dm	1,379	26.28	52	38	189	D
6/11/25 17:40	6/9/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.dm	-1,379	26.28	-52		189	D
6/11/25 17:13	6/9/25	AKBA	Akebia Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	M.d	132	3.06	43	19	267	D
6/11/25 17:13	6/9/25	AKBA	Akebia Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.d	-132	3.06	-43		267	D
6/11/25 17:04	6/9/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	3	4	M.dm	1,257	25.13	50	15	374	D
6/11/25 17:04	6/9/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	3	4	S.dm	-1,257	25.13	-50		374	D
6/11/25 17:00	6/9/25	VRDN	Viridian Therapeutics, Inc.De	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.dm	166	11.80	14	0	3,460	I
6/11/25 17:00	6/10/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	12	M.dm	14,542	28.77	505	8	6,474	D
6/11/25 17:00	6/10/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	12	S.dm	-14,542	28.77	-505		6,474	D
6/11/25 17:00	6/10/25	PHIO	Phio Pharmaceuticals Corp.	DE	Health	Drug	Pharmaceutical Preparations	2	5	P.m	27	2.13	13	42	43	D
6/11/25 16:33	6/10/25	SIGA	Siga Technologies Inc	DE	Health	Drug	Pharmaceutical Preparations	7	8	M.d	0	0.00	128	31	541	D
6/11/25 16:15	6/9/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	9	S.dm	-1,908	1.32	-1,451		7,805	I
6/11/25 09:14	6/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	1	2	M.d	38	2.51	15	11	153	D
6/11/25 09:14	6/9/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-38	2.51	-15		153	D
6/10/25 20:07	6/10/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	2	5	S.d	-846	4.43	-191		1,898	D
6/10/25 17:26	6/9/25	CNTX	Context Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	P	107	0.6692	160	15	1,242	I
6/10/25 17:25	6/4/25	ASBP	Aspire Biopharma Holdings, Inc.	E9	Health	Drug	Pharmaceutical Preparations	1	2	P.m	16	0.3900	40		20	D
6/10/25 17:00	6/6/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	19	M.d	672	4.89	137	2	5,830	D
6/10/25 17:00	6/9/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	19	S.d	-672	4.89	-137		5,830	D
6/10/25 16:39	6/9/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	9	11	S.dm	-210	2.62	-80		390	D
6/10/25 15:06	6/9/25	AYTU	Aytu Biopharma, Inc	DE	Health	Drug	Pharmaceutical Preparations	3	3	P.d	125	1.50	84	68	206	D
6/10/25 11:22	6/6/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	14	16	M.d	3,536	26.13	135	48	415	D
6/9/25 17:19	6/5/25	RFL	Rafael Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	16,743	1.28	13,080	813	14,689	I
6/9/25 16:20	6/6/25	ACRS	Aclaris Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	8	M.d	0	0.00	48	2	2,774	D
6/9/25 06:03	6/5/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	11	P.dm	152	0.8225	185	14	1,512	D
6/6/25 18:04	6/6/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S	-711	6.24	-114		2,317	D
6/6/25 17:58	6/5/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-65	12.58	-5		7	D
6/6/25 17:49	6/4/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	2	10	S.dm	-50,009	8.09	-6,185		53,995	D
6/6/25 17:44	6/4/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P.m	725	2.88	252	42	846	D
6/6/25 16:47	6/5/25	KRON	Kronos Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-22	0.8678	-25		139	D
6/6/25 16:26	6/4/25	CRVS	Corvus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	2,025	3.50	578	30	2,498	D
6/6/25 16:20	6/2/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.dm	-30,949	10.19	-3,036		3,959	D
6/6/25 16:07	6/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-74	13.35	-6		363	D
6/6/25 08:39	5/1/25	CPIX	Cumberland Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	4	12	P.m	20	4.91	4	0	6,061	D
6/5/25 21:44	6/3/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	6	S	-121	3.74	-32		578	D
6/5/25 20:53	6/3/25	SXTP	60 Degrees Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	14	2.88	5	46	16	D
6/5/25 19:25	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	19	S.adm	-7,856	23.69	-332		16,360	M
6/5/25 19:17	6/3/25	YMAB	Y-Mabs Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	206	2.00	103	31	433	D
6/5/25 18:01	6/4/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	8	21	S.d	-653	5.70	-115		281	D
6/5/25 17:40	6/4/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-523	26.23	-20		221	D
6/5/25 16:42	6/3/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	P.d	180	1.50	120	7	1,893	I
6/5/25 16:22	6/3/25	BPMC	Blueprint Medicines Corp	DE	Health	Drug	Pharmaceutical Preparations	5	9	S.d	-2,351	85.55	-27		453	D
6/5/25 16:20	6/3/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	6	29	M.d	1,811	6.26	289	7	4,334	D
6/5/25 16:20	6/4/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	6	29	S.d	-1,811	6.26	-289		4,334	D
6/5/25 09:11	6/4/25	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	29	2.85	10	2	570	D
6/4/25 18:04	6/2/25	TBPH	Theravance Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	1	2	S	-300	10.71	-28		370	D
6/4/25 17:37	6/3/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	4	4	M.d	206	13.12	16	16	112	D
6/4/25 16:50	6/2/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	2	4	S.m	-10,464	99.07	-106		1,718	D
6/4/25 16:34	6/2/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	6	26	S.dm	-8,455	14.13	-598		673	D
6/4/25 16:31	6/3/25	ZTS	Zoetis Inc.		Health	Drug	Pharmaceutical Preparations	4	4	S.d	-111	5.24	-21		49	D
6/4/25 16:30	4/13/25	CELU	Celularity Inc	DE	Health	Drug	Pharmaceutical Preparations	4	5	M.d	0	0.00	10	0	2,908	D
6/4/25 16:01	6/4/25	MTVA	Metavia Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	3,310	0.7100	4,662	87	10,040	D
6/4/25 15:23	6/4/25	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	S	-9	3.25	-3	0	710	D
6/3/25 21:21	6/3/25	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	P.d	1,275	7.31	174	24	895	D
6/3/25 18:34	5/29/25	CKPT	Checkpoint Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-240	1.88	-127		5,206	D
6/3/25 18:00	5/31/25	ASRT	Assertio Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	M.d	0	0.00	281	72	670	D
6/3/25 16:20	6/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	6	6	S	-390	7.37	-53		4,630	D
6/3/25 16:10	5/30/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	5	10	M.dm	32,175	208.20	155		120	D
6/3/25 16:10	5/30/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	5	10	S.dm	-32,175	208.20	-155		120	D
6/2/25 18:00	5/29/25	LGVN	Longeveron Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.m	-37	1.30	-28		952	D
6/2/25 17:03	5/30/25	PEPG	Pepgen Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	P	72	1.20	60	73	142	D
6/2/25 17:01	5/30/25	SMMT	Summit Therapeutics Inc.		Health	Drug	Pharmaceutical Preparations	2	2	M.d	394	2.64	149	0	1,182,986	I
6/2/25 16:30	5/30/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-31	7.32	-4		11	D
6/2/25 07:59	5/29/25	SVRA	Savara Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	437	2.73	160	6	2,774	D
6/2/25 07:53	5/30/25	IOBT	Io Biotech, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	21	1.39	15		15	D
5/29/25 16:01	5/27/25	GYRE	Gyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	10	S.dm	-835	1.14	-734		3,540	I
5/28/25 20:06	5/23/25	LFCR	Lifecore Biomedical, Inc. De	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.m	-9,871	6.62	-1,491		1,714	I
5/28/25 16:30	5/27/25	SILO	Silo Pharma, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	P	4	0.4329	10	5	198	D
5/28/25 16:08	5/23/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-399	5.88	-68		429	D
5/27/25 18:31	5/27/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	4	13	M.dm	8,105	11.72	691	251	967	D
5/27/25 18:31	5/27/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	4	13	S.dm	-8,105	11.72	-691		967	D
5/27/25 17:56	5/27/25	FBLG	Fibrobiologics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	17	0.8400	20	178	31	D
5/27/25 16:13	5/27/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	2	2	S	-1,653	734.65	-2		34	D
5/23/25 16:46	5/21/25	AEON	Aeon Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.m	85	0.4974	170	176	267	D
5/23/25 16:06	5/21/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	P.m	234	3.20	73	1	6,110	I
5/22/25 18:27	5/21/25	ATOS	Atossa Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	17	0.7951	21	84	46	D
5/22/25 17:00	5/20/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	5,478	8.52	643		316	D
5/22/25 17:00	5/20/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-5,478	8.52	-643		316	D
5/22/25 16:05	5/20/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	14	S	-330	5.30	-62		2,355	D
5/22/25 16:03	5/20/25	MGNX	Macrogenics Inc	DE	Health	Drug	Pharmaceutical Preparations	9	9	M.d	0	0.00	59	80	132	D
5/21/25 20:08	5/19/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-29	0.6700	-44		1,684	D
5/21/25 19:11	5/19/25	XOMA	Xoma Royalty Corp		Health	Drug	Pharmaceutical Preparations	4	9	M.dm	1,877	12.89	146	999%	155	D
5/21/25 19:11	5/20/25	XOMA	Xoma Royalty Corp		Health	Drug	Pharmaceutical Preparations	4	9	S.dm	-1,877	12.89	-146		155	D
5/21/25 16:58	5/21/25	INO	Inovio Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	12	M.d	0	0.00	50	22	284	D
5/21/25 16:01	5/21/25	ZOMDF	Zomedica Corp.	A0	Health	Drug	Pharmaceutical Preparations	4	4	P	129	0.0602	2,143	13	18,209	D
5/21/25 12:57	5/20/25	MDCX	Medicus Pharma Ltd.	A6	Health	Drug	Pharmaceutical Preparations	1	1	S	-579	7.72	-75		3,249	I
5/20/25 19:54	5/20/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.m	-574	8.12	-71		576	D
5/20/25 18:03	5/16/25	RLMD	Relmada Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	4	4	P.m	461	0.4712	979	135	1,703	D
5/20/25 17:58	5/20/25	BMRN	Biomarin Pharmaceutical Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-124	60.05	-2		47	D
5/20/25 17:05	5/17/25	JAGX	Jaguar Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	0	0.00	0	0	1	D
5/20/25 16:35	5/16/25	HCWB	Hcw Biologics Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	9	P.d	3,045	22.83	133	30	582	D
5/20/25 16:14	5/16/25	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-9	0.5800	-16		1,930	D
5/20/25 16:00	5/15/25	INZY	Inozyme Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	162	0.8476	191	70	465	D
5/19/25 18:35	5/15/25	ZYME	Zymeworks Inc.		Health	Drug	Pharmaceutical Preparations	1	6	P.m	10,084	11.82	853	5	17,884	I
5/19/25 18:30	5/19/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S	-344	7.09	-48		153	D
5/19/25 17:54	5/15/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	167	1.71	98	5	2,102	D
5/19/25 17:54	5/16/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-167	1.71	-98		2,102	D
5/19/25 17:33	4/4/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.m	-6,013	1.85	-3,242		4,670	D
5/19/25 17:07	5/15/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	2	2	S	-224	496.52	0		28	D
5/19/25 16:54	5/16/25	JBIO	Jade Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	44	7.40	6		6	D
5/19/25 16:05	5/15/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	3	1.71	2	8	27	D
5/19/25 16:05	5/16/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-3	1.71	-2		27	D
5/19/25 16:04	5/19/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	4	P	242	8.13	30	11	308	D
5/19/25 07:32	5/16/25	SRPT	Sarepta Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	792	24.31	33	1	3,217	D
5/16/25 20:07	5/16/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	5	5	M.d	0	0.00	1,640	50	4,919	D
5/16/25 16:15	5/15/25	THAR	Tharimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	1	1.30	1		1	D
5/16/25 16:05	5/14/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-2	1.12	-2		27	D
5/15/25 18:48	5/13/25	APUS	Apimeds Pharmaceuticals Us, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	P.dm	2,107	3.79	556	9	7,088	D
5/15/25 17:08	5/15/25	TNXP	Tonix Pharmaceuticals Holding Corp.	NV	Health	Drug	Pharmaceutical Preparations	1	1	P	86	21.55	4	999%	4	D
5/15/25 16:43	5/14/25	NGNE	Neurogene Inc.		Health	Drug	Pharmaceutical Preparations	1	1	S	-103	15.15	-7		21	D
5/15/25 16:09	3/31/25	OGN	Organon & Co.		Health	Drug	Pharmaceutical Preparations	11	16	M.d	652	1.72	379	80	851	D
5/14/25 21:55	5/12/25	KTTA	Pasithea Therapeutics Corp.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-1	0.8250	-1		40	D
5/14/25 18:08	5/12/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	P.dm	496	0.9105	545	3	20,919	I
5/14/25 18:00	5/12/25	VTRS	Viatris Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.d	536	5.30	101	43	335	D
5/14/25 17:00	5/12/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S	-17	1.40	-12		238	M
5/14/25 16:15	5/12/25	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.dm	1,572	9.58	164	2	9,686	D
5/14/25 16:11	5/14/25	CRVO	Cervomed Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	36	8.46	4	334	6	D
5/13/25 18:36	5/12/25	NVCT	Nuvectis Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	P.m	655	8.59	76	3	2,943	I
5/13/25 17:52	5/13/25	LXRX	Lexicon Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	M.d	0	0.00	221	0	46,491	D
5/13/25 17:05	5/12/25	GNLX	Genelux Corp	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-78	2.92	-27		374	D
5/13/25 16:20	5/9/25	GERN	Geron Corp	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	16	1.18	13		13	D
5/12/25 16:15	5/9/25	BSPK	Bespoke Extracts, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	P.m	0	0.1050	2	0	2,495	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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