Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
11/7/25 21:00	9/3/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	3	14	S.dm	-109,156	12.21	-8,937		67,807	D
11/7/25 18:03	9/4/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	12	S.dm	-36,931	47.32	-781		7,327	I
11/7/25 17:13	11/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	14	68	S.dm	-108,018	55.78	-1,936		855	D
11/7/25 17:10	11/5/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	7	28	M.dm	22,437	53.79	417	16	2,999	D
11/7/25 17:10	11/5/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	7	28	S.dm	-22,437	53.79	-417		2,999	D
11/7/25 16:58	11/6/25	EVOK	Evoke Pharma Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-96	10.65	-9		154	I
11/7/25 16:46	11/6/25	ZOMDF	Zomedica Corp.	A0	Health	Drug	Pharmaceutical Preparations	1	1	P	20	0.0800	253	5	5,509	D
11/7/25 16:30	8/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	11	34	S.dm	-27,819	25.46	-1,092		10,500	I
11/7/25 16:30	9/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	8	88	S.dm	-278,241	280.66	-991		725	D
11/7/25 16:23	11/6/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	5	9	S.d	-4,501	33.25	-135		3,528	D
11/7/25 16:20	11/7/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-229	7.58	-30		108	D
11/7/25 16:20	8/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	9	S.dm	-83,935	357.12	-235		2,070	D
11/7/25 16:09	10/22/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	3	13	S.dm	-825	4.27	-193		6,722	D
11/7/25 16:01	11/5/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	7	9	S	-1,005	11.47	-88		4,792	D
11/6/25 20:25	11/4/25	MBRX	Moleculin Biotech, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	M.d	2	0.0395	63	6	1,085	D
11/6/25 19:43	11/4/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	9	S.m	-2,995	1.39	-2,150		17,018	I
11/6/25 18:12	11/4/25	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-4	1.14	-4		243	D
11/6/25 17:46	9/9/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	1	7	S.dm	-4,152	40.67	-102		91	I
11/6/25 17:01	11/4/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	3	6	M.dm	13,483	23.81	566	175	890	D
11/6/25 17:01	11/4/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	3	6	S.dm	-13,483	23.81	-566		890	D
11/6/25 16:42	11/4/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	6	9	M.m	410	8.65	47	12	456	D
11/6/25 16:40	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	16	M.dm	474	3.12	152		0	D
11/6/25 16:40	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	16	S.dm	-474	3.12	-152	-100	0	D
11/6/25 16:11	11/5/25	OGN	Organon & Co.		Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	3	31	13	D
11/6/25 16:05	11/4/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	6	12	M.dm	11,052	25.48	434	109	830	D
11/6/25 16:05	11/4/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	6	12	S.dm	-11,052	25.48	-434		830	D
11/6/25 16:00	11/5/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	3	19	S	-1,717,044	847.21	-2,027		95,651	D
11/6/25 12:21	11/3/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	5	6	S.m	-121	9.32	-13		704	D
11/6/25 08:01	11/5/25	NVCT	Nuvectis Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	P.m	1,125	6.12	184	3	6,975	D
11/6/25 07:30	11/5/25	RLMD	Relmada Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	4	5	P.m	2,375	1.88	1,264	74	2,967	D
11/6/25 07:00	9/2/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	20	M.dm	9,339	25.72	363	18	2,419	D
11/6/25 07:00	9/2/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	20	S.dm	-9,339	25.72	-363		2,419	D
11/5/25 21:15	11/3/25	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-1,349	21.27	-63		800	D
11/5/25 19:01	9/2/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	16	S.dm	-58,202	74.60	-780		7,945	D
11/5/25 18:57	11/3/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	15	S.dm	-4,040	18.81	-215		1,735	D
11/5/25 18:17	10/1/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-675	13.51	-50		52	D
11/5/25 18:00	11/5/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	18	S.dm	-5,100	3.12	-1,633		1,679	D
11/5/25 17:22	11/3/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	2	4	S	-1,957	171.64	-11		171	D
11/5/25 17:00	9/2/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	12	M.d	3,360	26.57	126	10	1,417	D
11/5/25 17:00	9/2/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	12	S.d	-3,360	26.57	-126		1,417	D
11/5/25 16:30	11/3/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-13	0.1391	-91		97	D
11/5/25 16:20	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	19	M.dm	4,830	16.26	297		240	D
11/5/25 16:20	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	19	S.dm	-4,830	16.26	-297		240	D
11/5/25 16:20	11/3/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	1	3	S	-42	27.82	-2		77	D
11/5/25 16:08	11/3/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	6	14	M.d	61,460	92.23	666	121	1,218	D
11/5/25 16:08	11/3/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	6	14	S.d	-61,460	92.23	-666		1,218	D
11/5/25 16:05	11/4/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-244	9.51	-26		323	D
11/5/25 09:57	11/3/25	MTSR	Metsera, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-21	46.56	0	0	4,325	I
11/4/25 19:23	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	5	24	M.d	3,881	45.18	86	17	604	D
11/4/25 19:23	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	5	24	S.d	-3,881	45.18	-86		604	D
11/4/25 17:18	10/2/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	6	6	M.d	2,650	34.28	77	28	349	D
11/4/25 16:36	10/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	6	28	M.dm	27,698	22.30	1,242		409	D
11/4/25 16:36	10/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	6	28	S.dm	-27,698	22.30	-1,242		409	D
11/4/25 16:13	10/31/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	4	12	M.d	1,396	2.15	648	167	1,036	D
11/4/25 16:13	11/3/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	4	12	S.d	-1,396	2.15	-648		1,036	D
11/4/25 16:02	11/3/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	1	1	S	-720	83.59	-9		25	D
11/4/25 12:35	10/31/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	0	0.00	80	10	869	D
11/4/25 06:16	10/31/25	GLSI	Greenwich Lifesciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	21	9.26	2	0	5,573	D
11/3/25 20:00	10/31/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	7	M.dm	0	0.00	6	1	541	D
11/3/25 19:14	11/3/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-238	3.85	-62		182	D
11/3/25 17:25	5/14/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.m	1,177	3.09	381	3	12,249	I
11/3/25 17:25	6/9/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-1,177	3.09	-381		12,249	I
11/3/25 16:46	9/29/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	S.dm	-3,066	14.52	-211		1,795	D
11/3/25 16:37	11/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	4	M.d	751	26.81	28	61	74	D
11/3/25 16:37	11/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	4	S.d	-751	26.81	-28		74	D
11/3/25 16:30	10/30/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	10	M.d	6,687	69.70	96		9	D
11/3/25 16:30	10/30/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	10	S.d	-6,687	69.70	-96		9	D
11/3/25 16:10	10/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	13	M.d	726	26.04	28	32	114	D
11/3/25 16:10	10/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	13	S.d	-726	26.04	-28		114	D
10/31/25 17:15	10/31/25	OPK	Opko Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	213	1.42	150	0	248,083	I
10/31/25 16:31	8/29/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	34	M.dm	33,363	56.06	595	41	2,060	D
10/31/25 16:15	10/30/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	P	34	2.77	12	36	46	D
10/31/25 16:09	10/29/25	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	2	3	M.dm	28,492	561.83	51	578	59	D
10/31/25 15:30	10/29/25	SYBX	Synlogic, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	0	1.81	0		13	D
10/31/25 09:13	10/30/25	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	584	2.92	200	49	610	D
10/30/25 20:00	10/28/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	614	18.41	33	68	82	D
10/30/25 20:00	10/28/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-614	18.41	-33		82	D
10/30/25 16:31	10/28/25	MPLT	Maplight Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.d	108,700	17.00	6,394	38	23,384	I
10/29/25 20:43	10/23/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	P	191	4.82	40	3	1,483	I
10/29/25 16:24	10/27/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	676	3.38	200		0	D
10/29/25 16:24	10/27/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-676	3.38	-200	-100	0	D
10/29/25 16:11	10/27/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	2,722	1.58	1,721	32	7,102	D
10/28/25 21:05	9/4/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	21	M.dm	46,664	29.58	1,578	55	4,444	D
10/28/25 21:05	9/4/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	21	S.dm	-46,664	29.58	-1,578		4,444	D
10/28/25 19:51	10/28/25	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-3,932	35.31	-111		3,005	D
10/28/25 18:45	10/24/25	RNTX	Rein Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	1	1	P.m	423	1.38	306	30	1,322	I
10/28/25 17:00	10/24/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	12	S.m	-641	14.03	-46		445	D
10/28/25 16:10	10/25/25	MRSN	Mersana Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.d	15	1.72	9	259	12	D
10/28/25 16:10	10/27/25	MRSN	Mersana Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-15	1.72	-9		12	D
10/28/25 08:03	9/26/25	MBX	Mbx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	P.d	13,132	14.76	890	16	6,372	I
10/27/25 21:30	10/23/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	10	P.dm	3,002	8.20	366	45	1,177	D
10/27/25 19:56	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	3	17	M.dm	4,792	15.03	319	267	438	D
10/27/25 19:56	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	3	17	S.dm	-4,792	15.03	-319		438	D
10/27/25 19:24	10/20/25	RANI	Rani Therapeutics Holdings, Inc.	CA	Health	Drug	Pharmaceutical Preparations	2	2	S.dm	-16,972	2.12	-8,006		27,197	I
10/27/25 16:30	10/23/25	VRDN	Viridian Therapeutics, Inc.De	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	10,000	22.00	455	13	3,914	I
10/27/25 16:23	10/24/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.dm	892	10.70	83	62	218	D
10/27/25 16:23	10/24/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.dm	-892	10.70	-83		218	D
10/27/25 16:15	10/23/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	S.m	-26,351	7.59	-3,473		15,759	D
10/24/25 20:00	10/22/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	S.m	-1,305	1.26	-1,034		671	D
10/24/25 19:19	6/6/25	BOLT	Bolt Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	1	5.50	0	0	66	D
10/24/25 16:56	10/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	30	M.d	12,221	30.49	401	111	761	D
10/24/25 16:56	10/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	30	S.d	-12,221	30.49	-401		761	D
10/24/25 16:30	10/23/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	8	S.dm	-1,584	2.40	-661		124	D
10/24/25 16:01	10/15/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.dm	-76,347	78.54	-972		4,051	I
10/23/25 21:06	10/21/25	SMMT	Summit Therapeutics Inc.		Health	Drug	Pharmaceutical Preparations	3	5	P.m	22,969	18.18	1,264	0	1,244,269	I
10/23/25 19:49	10/21/25	NEUP	Neuphoria Therapeutics Inc.	C3	Health	Drug	Pharmaceutical Preparations	1	1	P	3,283	5.14	639	271	875	I
10/23/25 17:10	10/22/25	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	256	3.17	81	31	339	D
10/23/25 16:20	10/21/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	14	M.dm	11,157	25.84	432	23	2,298	D
10/23/25 16:20	10/21/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	14	S.dm	-11,157	25.84	-432		2,298	D
10/22/25 19:20	10/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	17	S.dm	-1,952	19.27	-101		2,176	I
10/22/25 16:15	10/20/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	19	2.42	8	90	17	D
10/20/25 20:00	9/12/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	1	16	S.m	-816	1.77	-460		4,483	I
10/20/25 19:13	10/17/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	5	9	M.d	64,798	142.98	453	188	694	D
10/20/25 19:13	10/17/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	5	9	S.d	-64,798	142.98	-453		694	D
10/20/25 18:58	10/16/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	2	5	S.m	-11,712	1.45	-8,061		8,198	D
10/20/25 09:11	10/17/25	GOVX	Geovax Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	5	0.5498	10	88	21	D
10/17/25 17:53	10/15/25	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	2	2	S	-180,635	17.75	-10,177	-100	11	I
10/17/25 16:28	10/16/25	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-29	21.07	-1		25	D
10/17/25 16:10	9/24/25	PRAX	Praxis Precision Medicines, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	33,682	103.27	326	8	4,439	D
10/17/25 16:05	10/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	5	5	M.d	0	0.00	1	1	209	D
10/17/25 14:01	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	M.d	1,867	5.31	352	23	1,871	D
10/17/25 14:01	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.d	-1,867	5.31	-352		1,871	D
10/16/25 18:14	10/15/25	AARD	Aardvark Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.dm	389	6.99	56	2	3,125	D
10/16/25 16:41	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	16	M.dm	4,229	11.45	369	114	693	D
10/16/25 16:41	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	16	S.dm	-4,229	11.45	-369		693	D
10/16/25 16:30	9/8/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	10	M.d	4,651	24.69	188	16	1,383	D
10/16/25 16:30	9/8/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	10	S.d	-4,651	24.69	-188		1,383	D
10/16/25 16:21	10/7/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-369	9.79	-38		216	D
10/16/25 16:15	8/14/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	S.m	-482	5.79	-83		2,055	D
10/16/25 16:01	10/14/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.m	-256	3.44	-74		468	D
10/15/25 19:04	10/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	6	S	-46,952	25.91	-1,812		14,617	D
10/15/25 17:15	10/14/25	QNRX	Quoin Pharmaceuticals, Ltd.	L3	Health	Drug	Pharmaceutical Preparations	1	1	P.d	129	8.49	15	999%	15	D
10/14/25 19:49	9/19/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	8	13	S.m	-24,675	89.31	-276		1,148	D
10/14/25 17:16	10/9/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	P.m	18,628	18.97	982	7	15,283	I
10/14/25 16:01	10/10/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	1	4	M.d	1,557	48.66	32		9	D
10/14/25 16:01	10/10/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.d	-1,557	48.66	-32		9	D
10/14/25 12:15	9/12/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S	-331	31.42	-11		222	D
10/10/25 20:06	10/8/25	ACET	Adicet Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	5,000	1.00	5,000	207	7,421	I
10/10/25 19:17	10/10/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	M.d	439	4.50	98	51	291	D
10/10/25 19:17	10/10/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.d	-439	4.50	-98		291	D
10/10/25 17:33	9/25/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	38	M.dm	24,419	31.27	781	47	2,434	D
10/10/25 16:56	10/8/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	6	13	S.dm	-69,483	251.55	-276	0	56,758	D
10/10/25 16:56	10/8/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	6	13	M.dm	69,483	251.55	276	0	56,758	D
10/9/25 16:22	8/19/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-21	0.8217	-25		54	D
10/9/25 13:37	10/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	3	6	M.d	83	5.88	14	8	195	D
10/9/25 13:37	10/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-83	5.88	-14		195	D
10/9/25 09:01	10/8/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	2	2	P.m	46,967	7.21	6,511		2,622	D
10/8/25 19:48	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-16	1.19	-14		717	D
10/8/25 17:37	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.dm	3,128	10.26	305	46	966	D
10/8/25 17:37	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.dm	-3,128	10.26	-305		966	D
10/8/25 16:45	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	14	14	M.d	0	0.00	9,355		0	D
10/8/25 16:16	10/7/25	CARM	Carisma Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	M.dm	145	0.2425	598		0	D
10/8/25 16:16	10/7/25	CARM	Carisma Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.dm	-145	0.2425	-598	-100	0	D
10/8/25 16:10	10/6/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	1	3	S.m	-42	3.56	-12		1,046	D
10/7/25 08:56	10/3/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	4	6	P	153	6.90	22	2	1,197	D
10/7/25 07:05	10/4/25	PRLD	Prelude Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	9	12	87	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	7	7	S.m	-93	8.41	-11		831	D
10/6/25 09:12	10/3/25	PMN	Promis Neurosciences Inc.	Z4	Health	Drug	Pharmaceutical Preparations	1	1	P	15	0.4912	30	203	45	D
10/3/25 21:58	10/2/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-836	0.2201	-3,800		7,800	D
10/3/25 21:27	9/2/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-1,525	132.63	-12		430	D
10/3/25 18:15	10/1/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.m	-1,725	28.75	-60		262	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	8	17	S.dm	-52,450	323.13	-162		222	D
10/3/25 16:56	9/3/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	8	S	-19	6.42	-3		209	D
10/3/25 16:07	10/2/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	2	2	S	-383	399.36	-1		20	D
10/3/25 13:18	10/2/25	SNGX	Soligenix, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	20	1.32	15	999%	16	D
10/2/25 16:51	10/1/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P.d	25	1.30	19	1	1,324	I
10/2/25 16:44	9/30/25	SAVA	Cassava Sciences Inc	DE	Health	Drug	Pharmaceutical Preparations	2	3	P.m	591	2.28	259	55	728	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-1,319	14.44	-91		7,288	D
10/2/25 16:10	10/1/25	FBRX	Forte Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	0	0.00	2	1	114	D
10/2/25 16:05	9/30/25	ALLR	Allarity Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	39		25	D
10/2/25 16:05	9/30/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	787	11.83	67		21	D
10/2/25 15:04	9/30/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	3	3	M.d	35,000	62.14	563	519	672	D
10/1/25 19:17	10/1/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	1	2	M.d	1,196	23.93	50		46	D
10/1/25 19:17	10/1/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-1,196	23.93	-50		46	D
10/1/25 17:16	9/30/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	6	9	S.dm	-25,665	1.05	-24,430		130,226	I
10/1/25 16:43	9/30/25	ZTS	Zoetis Inc.		Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	1		1	D
10/1/25 16:00	9/15/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	309	21.26	15	279	20	D
10/1/25 13:07	9/30/25	PEPG	Pepgen Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	30,640	3.20	9,575	62	25,020	D
9/29/25 19:30	9/8/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	7	P	1,108	8.65	128	10	1,406	D
9/24/25 19:42	9/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-1	2.62	0		16	D
9/23/25 17:32	9/19/25	XOMA	Xoma Royalty Corp	NV	Health	Drug	Pharmaceutical Preparations	4	6	M.d	156	2.21	71	62	185	D
9/22/25 09:35	9/18/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	11	P.dm	167	2.56	65	6	1,125	I
9/18/25 21:30	9/16/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-205	8.19	-25		861	M
9/18/25 16:36	9/16/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	7	7	P.d	54	0.1500	362	30	1,568	D
9/18/25 16:23	9/16/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	3	4	P.m	160	0.9380	170	57	469	D
9/18/25 16:06	9/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-117	2.79	-42		2,387	D
9/17/25 19:39	9/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-251	5.34	-47		1,032	D
9/17/25 17:22	9/8/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	3	8	P.dm	8,552	19.16	446	7	6,932	I
9/17/25 17:20	9/17/25	IMMX	Immix Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	10	1.99	5	0	1,727	D
9/16/25 21:21	9/10/25	BFRI	Biofrontera Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	0	0.00	225	999%	240	D
9/16/25 18:09	9/12/25	LBRX	Lb Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	4	P.d	75,000	15.00	5,000	243	7,060	M
9/16/25 18:00	9/15/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-678	25.03	-27		69	D
9/15/25 20:12	9/11/25	CAMP	Camp4 Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	7	7	P	8,555	1.53	5,589	185	8,605	D
9/12/25 20:00	9/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	2,648	27.60	96		56	D
9/12/25 20:00	9/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-2,648	27.60	-96		56	D
9/12/25 18:00	9/11/25	VTRS	Viatris Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-72	10.25	-7		35	D
9/12/25 17:30	9/11/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	3	6	M.d	705	5.02	140	12	1,321	D
9/12/25 17:30	9/11/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-705	5.02	-140		1,321	D
9/12/25 17:09	9/11/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	3	4	S.d	-1,554	7.32	-212		1,206	D
9/12/25 16:42	9/11/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-672	32.24	-21		94	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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