| 10/30/25 20:00 | 10/28/25 | JANX | Janux Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Meyer Andrew Hollman | CA | O | Chief Bu | 1 | S.d | -501 | 30.06 | 0 | -17 |  | 82 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 19:02 | 10/28/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Watanabe Todd | CA | DO | See Rema | 4 | S.m | -2,229 | 20.89 | 0 | -107 |  | 1,135 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 18:40 | 10/28/25 | VOR | Vor Biopharma Inc. |  | Health | BioPrd | Biological Products, (No Diag | Ra Capital Management, L.P. | MA | DT |  | 5 | S.m | -48,478 | 30.75 | 0 | -1,576 |  | 1,611 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 18:09 | 9/9/25 | PAHC | Phibro Animal Health Corp | DE | Health | Drug | Pharmaceutical Preparations | Bendheim Jack | NJ | DOT | P,CEO | 6 | S.dm | -3,855 | 40.56 | 0 | -95 |  | 91 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 18:06 | 10/30/25 | NRIX | Nurix Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Van Houte Hans | CA | O | CFO | 1 | S.d | -40 | 12.80 | 0 | -3 |  | 44 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 18:02 | 10/30/25 | NRIX | Nurix Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ring Christine | CA | O | GC | 1 | S.d | -47 | 12.80 | 0 | -4 |  | 51 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 18:01 | 10/30/25 | NRIX | Nurix Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hansen Gwenn | CA | O | Chief Sc | 1 | S.d | -52 | 12.80 | 0 | -4 |  | 77 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 18:00 | 10/28/25 | BGMS | Bio Green Med Solution, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Yap Kim Choy | N8 | T |  | 3 | S | -316 | 2.07 | 0 | -153 |  | 385 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:47 | 10/28/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | X0 | Health | Drug | Pharmaceutical Preparations | Ragosa Mark | X0 | O | CFO | 2 | S.d | -625 | 32.93 | 0 | -19 |  | 31 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:45 | 10/28/25 | TVTX | Travere Therapeutics, Inc. | CA | Health | Drug | Pharmaceutical Preparations | Dube Eric M | CA | DO | CEO | 1 | S.dm | -3,638 | 30.32 | 0 | -120 |  | 419 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:45 | 10/28/25 | TVTX | Travere Therapeutics, Inc. | CA | Health | Drug | Pharmaceutical Preparations | Heerma Peter | CA | O | Chief Co | 1 | S | -80 | 30.00 | 0 | -3 |  | 125 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:44 | 10/28/25 | RYTM | Rhythm Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Shulman Joseph | MA | O | Chief Te | 5 | S.d | -4,486 | 106.29 | 0 | -42 |  | 9 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:37 | 8/21/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Mahon Paul A | MD | O | EVP,GC | 7 | S.d | -29,904 | 388.37 | 0 | -77 |  | 37 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:34 | 10/29/25 | MMM | 3M Co | DE | Health | MdEq | Surgical & Medical Instrument | Murphy Mark W. | MN | O | EVP,Chie | 1 | S.d | -3,175 | 166.55 | 0 | -19 |  | 7 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:30 | 10/27/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | 19 | S.dm | -62,670 | 423.44 | 0 | -148 |  | 644 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:30 | 10/28/25 | VIR | Vir Biotechnology, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Svf Endurance (Cayman) Ltd | E9 | T |  | 8 | S.m | -12,580 | 5.96 | 0 | -2,110 |  | 16,160 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:25 | 9/2/25 | CYTK | Cytokinetics Inc |  | Health | Drug | Pharmaceutical Preparations | Blum Robert I | CA | DO | P,CEO | 6 | S | -1,574 | 52.48 | 0 | -30 |  | 387 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:23 | 10/29/25 | UHS | Universal Health Services Inc | DE | Health | Health | General Medical & Surgical Ho | Sussman Elliot J Md Mba | FL | D |  | 1 | S.d | -218 | 225.70 | 0 | -1 |  | 6 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:19 | 10/28/25 | RLAY | Relay Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Rahmer Peter | MA | O | See rema | 1 | S.m | -300 | 7.40 | 0 | -41 |  | 337 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:15 | 10/28/25 | RLAY | Relay Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Catinazzo Thomas | MA | O | CFO | 1 | S | -158 | 7.29 | 0 | -22 |  | 314 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:12 | 10/28/25 | RLAY | Relay Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Bergstrom Donald A | MA | O | P,R,D | 1 | S | -225 | 7.29 | 0 | -31 |  | 522 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 08:49 | 10/28/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Jaen Juan C. | CA | O | P | 1 | S.m | -2,011 | 20.76 | 0 | -97 |  | 1,459 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 21:35 | 10/27/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Chapman Steven Leonard | TX | DO | CEO,P | 5 | S.dm | -6,802 | 163.13 | 0 | -42 |  | 164 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 21:35 | 10/27/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Brophy Michael Burkes | TX | O | CFO | 4 | S.dm | -1,898 | 183.76 | 0 | -10 |  | 70 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 21:05 | 10/27/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Sheena Jonathan | TX | DH | CO-FOUND | 5 | S.dm | -4,389 | 173.60 | 0 | -25 |  | 311 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 21:05 | 10/27/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Rabinowitz Daniel | TX | O | SEC.,GC | 3 | S.dm | -691 | 180.75 | 0 | -4 |  | 204 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 21:05 | 10/27/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Moshkevich Solomon | TX | O | P,CLINIC | 6 | S.m | -1,993 | 161.05 | 0 | -12 |  | 124 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 21:05 | 10/27/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Fesko John | TX | O | P,CHIEF | 3 | S.m | -497 | 182.32 | 0 | -3 |  | 153 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 19:48 | 10/28/25 | ISRG | Intuitive Surgical Inc | DE | Health | Orthop | Orthopedic, Prosthetic & Surg | Curet Myriam | CA | O | EVP,Chie | 1 | S.dm | -4,215 | 548.34 | 0 | -8 |  | 0 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 19:22 | 10/27/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Evnin Luke | MA | D |  | 1 | S.m | -286 | 1.62 | 0 | -177 |  | 4,133 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 19:21 | 10/27/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mpm Bioventures 2014, L.P. | MA | T |  | 1 | S.m | -446 | 1.62 | 0 | -276 |  | 6,443 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 19:21 | 10/27/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gadicke Ansbert | MA | T |  | 1 | S.m | -446 | 1.62 | 0 | -276 |  | 6,443 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 17:19 | 10/29/25 | KYMR | Kymera Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Mainolfi Nello | MA | DO | CEO | 2 | S.d | -3,300 | 55.00 | 0 | -60 |  | 660 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 17:12 | 10/27/25 | MEDP | Medpace Holdings, Inc. | DE | Health | Biolab | Commercial Physical & Biologi | Geiger Jesse J | OH | O | P | 1 | S.dm | -13,863 | 602.00 | 0 | -23 |  | 37 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 17:10 | 10/27/25 | BBIO | Bridgebio Pharma, Inc. | DE | Health | Drug | Pharmaceutical Preparations | McCormick Frank | CA | D |  | 2 | S.d | -4,040 | 53.41 | 0 | -76 |  | 963 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 17:05 | 10/29/25 | AURA | Aura Biosciences, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Elazzouzi Amy | MA | O | SVP,Fina | 2 | S.d | -57 | 6.66 | 0 | -9 |  | 87 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 17:05 | 10/29/25 | AURA | Aura Biosciences, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | De Los Pinos Elisabet | MA | DO | See Rema | 1 | S | -57 | 6.35 | 0 | -9 |  | 602 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 17:04 | 8/18/25 | SER | Serina Therapeutics, Inc. | AL | Health | Drug | Pharmaceutical Preparations | Moreadith Randall | AL | O | Chief Sc | 8 | S.dm | -498 | 6.20 | 0 | -80 | -100 | 0 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:58 | 10/27/25 | MEDP | Medpace Holdings, Inc. | DE | Health | Biolab | Commercial Physical & Biologi | Ewald Stephen P | OH | O | GC,Corp. | 1 | S.d | -9,120 | 598.85 | 0 | -15 |  | 13 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:52 | 10/27/25 | MEDP | Medpace Holdings, Inc. | DE | Health | Biolab | Commercial Physical & Biologi | Burwig Susan E | OH | O | EVP,Oper | 2 | S | -6,010 | 500.84 | 0 | -12 |  | 66 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:31 | 10/27/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Shair Matthew | MA | D |  | 1 | S.m | -6,015 | 100.26 | 0 | -60 |  | 1,586 | M |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:30 | 10/27/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Adair Jason | NC | O | Chief Bu | 3 | S.dm | -841 | 27.23 | 0 | -31 |  | 176 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:30 | 10/27/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Boyle Dana | NC | O | Chief Ac | 3 | S | -62 | 23.85 | 0 | -3 |  | 187 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:29 | 10/22/25 | MLSS | Milestone Scientific Inc. | DE | Health | Orthop | Orthopedic, Prosthetic & Surg | Bp4 S.R.L. | L6 | T |  | 6 | S.m | -174 | 0.4596 | 0 | -378 |  | 9,257 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:24 | 10/27/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hattersley Gary | NY | O | Chief Sc | 1 | S.d | -502 | 5.02 | 0 | -100 | -100 | 0 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:14 | 10/28/25 | GILD | Gilead Sciences, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | O'Day Daniel Patrick | CA | DO | CB,CEO | 3 | S | -3,447 | 114.89 | 0 | -30 |  | 596 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:02 | 10/27/25 | AGIO | Agios Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gheuens Sarah | MA | O | Chief Me | 1 | S.d | -145 | 43.92 | 0 | -3 |  | 62 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 13:13 | 10/27/25 | BEAM | Beam Therapeutics Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Fmr LLC | MA | TH | See Rema | 2 | S | -22 | 30.12 | 0 | -1 | 0 | 6,305 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 09:20 | 10/27/25 | IRMD | Iradimed Corp | DE | Health | MdEq | Surgical & Medical Instrument | Susi Roger E. | FL | DOT | CEO,P,CB | 7 | S | -2,548 | 72.79 | 0 | -35 |  | 4,583 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 08:54 | 10/28/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Goeltz II Robert C. | CA | O | CFO | 1 | S | -100 | 20.00 | 0 | -5 |  | 92 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 19:51 | 10/28/25 | VKTX | Viking Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mancini Marianna | CA | O | COO | 1 | S | -216 | 35.00 | 0 | -6 |  | 382 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 19:49 | 10/27/25 | VKTX | Viking Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Rowland Charles A Jr | CA | D |  | 1 | S.d | -2,134 | 35.57 | 0 | -60 |  | 30 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 19:48 | 10/28/25 | VKTX | Viking Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Lian Brian | CA | DO | P,CEO | 1 | S | -1,365 | 35.01 | 0 | -39 |  | 2,419 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 19:47 | 10/28/25 | VKTX | Viking Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Zante Greg | CA | O | CFO | 1 | S | -216 | 35.00 | 0 | -6 |  | 174 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 18:00 | 10/24/25 | BGMS | Bio Green Med Solution, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ong Yee Lung | N8 | T |  | 2 | S | -854 | 5.49 | 0 | -156 |  | 269 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 17:44 | 10/27/25 | BSX | Boston Scientific Corp | DE | Health | MdEq | Surgical & Medical Instrument | Zane Ellen M | MA | D |  | 1 | S.m | -1,307 | 101.38 | 0 | -13 |  | 24 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 17:14 | 10/24/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | Goswami Joydeep | WA | D |  | 2 | S | -48 | 16.10 | 0 | -3 |  | 47 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 17:00 | 10/24/25 | CVKD | Cadrenal Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Szot Matthew K | FL | O | CFO | 6 | S.m | -328 | 14.03 | 0 | -23 |  | 31 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 17:00 | 10/24/25 | CVKD | Cadrenal Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Pham Quang X | FL | DOT | CEO,CB | 6 | S.m | -312 | 14.04 | 0 | -22 |  | 413 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 16:30 | 10/27/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Benkowitz Michael | MD | O | P,COO | 9 | S.dm | -82,798 | 421.63 | 0 | -196 |  | 3 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 16:23 | 10/27/25 | HIMS | Hims & Hers Health, Inc. | DE | Health | Health | Offices & Clinics of Doctors | Boughton Soleil | CA | O | GC | 6 | S | -811 | 51.69 | 0 | -16 |  | 166 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 16:15 | 10/24/25 | CDRE | Cadre Holdings, Inc. | DE | Health | Orthop | Orthopedic, Prosthetic & Surg | Williams Brad | FL | O | P | 3 | S | -496 | 40.00 | 0 | -12 |  | 114 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 16:15 | 10/24/25 | AVAH | Aveanna Healthcare Holdings, Inc. | DE | Health | Health | Home Health Care Services | Vigano Paul R | CT | T |  | 2 | S | -103,500 | 9.00 | 0 | -11,500 |  | 41,566 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 16:15 | 10/24/25 | AVAH | Aveanna Healthcare Holdings, Inc. | DE | Health | Health | Home Health Care Services | J.H. Whitney Equity Partners Vii, LLC | CT | T |  | 2 | S | -86,382 | 9.00 | 0 | -9,598 |  | 37,495 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 16:15 | 10/24/25 | AVAH | Aveanna Healthcare Holdings, Inc. | DE | Health | Health | Home Health Care Services | Williams Robert M Jr | CT | T |  | 2 | S | -103,500 | 9.00 | 0 | -11,500 |  | 41,566 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 16:10 | 10/27/25 | MRSN | Mersana Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bala Mohan | MA | O | SVP,Chie | 1 | S.d | -1 | 9.90 | 0 | 0 |  | 3 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 15:40 | 10/24/25 | ATEC | Alphatec Holdings, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Sponsel David | CA | O | EVP,Sale | 2 | S.m | -3,246 | 15.46 | 0 | -210 |  | 532 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 11:58 | 10/27/25 | BDX | Becton Dickinson & Co | NJ | Health | MdEq | Surgical & Medical Instrument | Feld Michael | NJ | O | EVP,P,Li | 3 | S | -32 | 188.30 | 0 | 0 |  | 8 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 20:35 | 10/24/25 | EXAS | Exact Sciences Corp |  | Health | Health | Medical Laboratories | Zanotti Katherine S | WI | D |  | 1 | S | -780 | 65.00 | 0 | -12 |  | 61 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 19:56 | 10/27/25 | CNTA | Centessa Pharmaceuticals Plc | X0 | Health | Drug | Pharmaceutical Preparations | Accardi Mario Alberto | X0 | O | P,Orexin | 3 | S.d | -515 | 22.22 | 0 | -23 |  | 206 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 18:19 | 10/24/25 | FDMT | 4D Molecular Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Bizily Scott | CA | O | GC | 4 | S.d | -92 | 10.09 | 0 | -9 |  | 8 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 17:59 | 10/27/25 | CYTK | Cytokinetics Inc |  | Health | Drug | Pharmaceutical Preparations | Wierenga Wendell | CA | D |  | 1 | S.d | -257 | 58.68 | 0 | -4 |  | 32 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 17:19 | 10/23/25 | PMVP | Pmv Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | 2 | S | -2,420 | 1.61 | 0 | -1,500 |  | 5,975 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 16:23 | 10/24/25 | CRBP | Corbus Pharmaceuticals Holdings, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cohen Yuval | MA | DO | CEO | 1 | S.dm | -471 | 17.05 | 0 | -28 |  | 138 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 16:22 | 10/24/25 | CRBP | Corbus Pharmaceuticals Holdings, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Moran Sean F. | MA | O | CFO | 1 | S.d | -221 | 17.02 | 0 | -13 |  | 73 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 16:15 | 10/23/25 | TNGX | Tango Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Third Rock Ventures Iv, L.P. | MA | T |  | 6 | S.m | -26,351 | 7.59 | 0 | -3,473 |  | 15,759 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 16:11 | 10/24/25 | ISRG | Intuitive Surgical Inc | DE | Health | Orthop | Orthopedic, Prosthetic & Surg | Guthart Gary S | CA | DO | Exec Cha | 2 | S.d | -31,171 | 511.34 | 0 | -61 |  | 1,266 | M |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 16:05 | 10/23/25 | TWST | Twist Bioscience Corp | DE | Health | BioPrd | Biological Products, (No Diag | Finn Patrick John | CA | O | P,COO | 5 | S | -978 | 31.32 | 0 | -31 |  | 235 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 15:56 | 10/24/25 | ISRG | Intuitive Surgical Inc | DE | Health | Orthop | Orthopedic, Prosthetic & Surg | Barratt Craig H | CA | D |  | 1 | S.d | -1,202 | 548.01 | 0 | -2 |  | 27 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 15:36 | 10/24/25 | ISRG | Intuitive Surgical Inc | DE | Health | Orthop | Orthopedic, Prosthetic & Surg | Rosa David J. | CA | DO | CEO (CEO | 1 | S.d | -13,415 | 547.55 | 0 | -25 |  | 234 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 21:05 | 10/24/25 | ADMA | Adma Biologics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Grossman Adam S | NJ | DO | P,CEO | 3 | S.d | -1,029 | 16.34 | 0 | -63 |  | 3,756 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 20:18 | 10/22/25 | GALT | Galectin Therapeutics Inc | NV | Health | Drug | Pharmaceutical Preparations | 10X Fund, L.P. | GA | T |  | 1 | S | -247 | 4.94 | 0 | -50 |  | 5,872 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 20:00 | 10/23/25 | KALA | Kala Bio, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Iwicki Mark T | MA | D |  | 1 | S | -125 | 0.8100 | 0 | -155 |  | 104 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 20:00 | 10/22/25 | KALA | Kala Bio, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Reumuth Mary | MA | O | CFO | 1 | S.m | -28 | 0.8297 | 0 | -33 |  | 29 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 20:00 | 10/22/25 | KALA | Kala Bio, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bazemore Todd | MA | D |  | 1 | S | -40 | 0.8300 | 0 | -48 |  | 36 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 20:00 | 10/22/25 | KALA | Kala Bio, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Brazzell Romulus K | MA | O | SEE REMA | 1 | S | -39 | 0.8300 | 0 | -47 |  | 36 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 20:00 | 10/22/25 | KALA | Kala Bio, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kharabi Darius | MA | O | CHIEF BU | 1 | S | -17 | 0.8300 | 0 | -21 |  | 42 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 18:49 | 10/23/25 | RXRX | Recursion Pharmaceuticals, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Gibson Christopher | UT | DO | CEO | 6 | S.d | -5,869 | 5.25 | 0 | -1,118 |  | 995 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 18:10 | 10/22/25 | DGX | Quest Diagnostics Inc | DE | Health | Health | Medical Laboratories | Pfeiffer Gary M | NJ | D |  | 1 | S.d | -270 | 182.40 | 0 | -1 |  | 29 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 17:03 | 10/22/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | De Greef Roderick | WA | DO | P,CEO | 1 | S | -1,032 | 27.30 | 0 | -38 |  | 490 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 16:56 | 10/22/25 | RNA | Avidity Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hughes Steven George | CA | O | Chief Me | 6 | S.d | -3,919 | 43.00 | 0 | -91 |  | 39 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 16:38 | 10/22/25 | IMVT | Immunovant, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Geffner Michael | NY | O | Chief Me | 2 | S | -70 | 18.13 | 0 | -4 |  | 221 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 16:36 | 10/22/25 | IMVT | Immunovant, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Stout Jay S | NY | O | CTO | 2 | S | -74 | 17.98 | 0 | -4 |  | 203 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 16:30 | 10/23/25 | ALZN | Alzamend Neuro, Inc. | DE | Health | Drug | Pharmaceutical Preparations | McGrath Lynne Fahey | GA | D |  | 1 | S | 0 | 2.30 | 0 | 0 |  | 0 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 16:09 | 10/22/25 | AXGN | Axogen, Inc. | MN | Health | ElcMd | Electromedical & Electrothera | Burke William P. Mr. | FL | D |  | 3 | S.m | -624 | 18.14 | 0 | -34 |  | 2 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 16:01 | 10/22/25 | IRON | Disc Medicine, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ai Dmi LLC | NY | T |  | 1 | S | -59,873 | 80.47 | 0 | -744 |  | 2,814 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/23/25 18:20 | 10/21/25 | ALLO | Allogene Therapeutics, Inc. |  | Health | BioPrd | Biological Products, (No Diag | Parker Geoffrey M. | CA | O | CFO | 1 | S | -46 | 1.26 | 0 | -37 |  | 1,277 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/23/25 18:00 | 10/21/25 | BGMS | Bio Green Med Solution, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Fitters Diversified Berhad | N8 | T |  | 5 | S | -1,777 | 4.23 | 0 | -420 |  | 557 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/23/25 16:20 | 10/21/25 | APLS | Apellis Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Sullivan Timothy Eugene | MA | O | CFO | 2 | S.d | -1,470 | 27.89 | 0 | -53 |  | 171 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/23/25 09:30 | 10/20/25 | CSTL | Castle Biosciences Inc | DE | Health | Health | Medical Laboratories | Maetzold Derek J | TX | DO | P,Chief | 6 | S | -988 | 19.87 | 0 | -50 |  | 331 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 21:05 | 10/20/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Rabinowitz Matthew | TX | DO | Exec CB | 3 | S.m | -11,769 | 181.07 | 0 | -65 |  | 2,386 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 19:20 | 10/20/25 | ELVN | Enliven Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Lyssikatos Joseph P | CO | O | CHIEF SC | 5 | S.m | -771 | 20.56 | 0 | -38 |  | 940 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 18:57 | 10/20/25 | RANI | Rani Therapeutics Holdings, Inc. | CA | Health | Drug | Pharmaceutical Preparations | South Cone Investments Limited Partnership | F3 | T |  | 1 | S.m | -15,711 | 2.65 | 0 | -5,923 |  | 2,379 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 17:48 | 10/22/25 | BTSG | Brightspring Health Services, Inc. | DE | Health | Health | Home Health Care Services | Kkr Phoenix Aggregator L.P. | NY | T |  | 1 | S | -424,391 | 28.78 | 0 | -14,745 |  | 61,942 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 17:39 | 8/26/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cloonan Michael | MA | DO | P,CEO | 5 | S.dm | -6,328 | 31.64 | 0 | -200 |  | 547 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 17:09 | 10/20/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | X0 | Health | Drug | Pharmaceutical Preparations | Patel Sanj K | X0 | DO | CB,CEO | 1 | S.dm | -10,024 | 38.86 | 0 | -258 |  | 222 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 17:06 | 10/20/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | X0 | Health | Drug | Pharmaceutical Preparations | Megna Michael R | X0 | O | CHIEF AC | 3 | S.d | -2,896 | 36.90 | 0 | -78 |  | 38 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 17:02 | 9/11/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | Werner Sean | WA | O | CTO | 3 | S | -12 | 27.09 | 0 | 0 |  | 26 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 16:32 | 10/20/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Miller Deborah Ann | MA | O | GC | 2 | S.dm | -3,015 | 91.36 | 0 | -33 |  | 49 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 16:17 | 10/20/25 | HOLX | Hologic Inc | DE | Health | OthMd | X-Ray Apparatus & Tubes & Rel | Stamoulis Christiana | MA | D |  | 1 | S.d | -541 | 73.07 | 0 | -7 |  | 47 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 16:10 | 10/22/25 | BTSG | Brightspring Health Services, Inc. | DE | Health | Health | Home Health Care Services | Rousseau Jon B | KY | DO | See Rema | 1 | S.d | -6,764 | 28.78 | 0 | -235 |  | 1,502 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 16:09 | 10/22/25 | BTSG | Brightspring Health Services, Inc. | DE | Health | Health | Home Health Care Services | Nalley Lisa A | KY | O | See Rema | 1 | S.d | -576 | 28.78 | 0 | -20 |  | 131 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/21/25 21:19 | 10/21/25 | MGTX | Meiragtx Holdings Plc |  | Health | BioPrd | Biological Products, (No Diag | Giroux Richard | NY | O | CFO,COO | 1 | S | -213 | 8.87 | 0 | -24 |  | 920 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/21/25 18:18 | 9/9/25 | CYTK | Cytokinetics Inc |  | Health | Drug | Pharmaceutical Preparations | Malik Fady Ibraham | CA | O | EVP Rese | 6 | S.d | -594 | 49.08 | 0 | -12 |  | 141 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/21/25 18:13 | 10/17/25 | ELVN | Enliven Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kintz Samuel | CO | DO | P,CEO | 6 | S.m | -763 | 20.35 | 0 | -38 |  | 929 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/21/25 17:45 | 10/17/25 | VOR | Vor Biopharma Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Reprogrammed Interchange LLC | CA | T |  | 12 | S.m | -27,680 | 4.15 | 0 | -6,665 |  | 38,303 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/21/25 17:12 | 10/21/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Booth Bruce | MA | D |  | 5 | S.m | -22,086 | 31.62 | 0 | -698 |  | 3,615 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/21/25 16:56 | 10/17/25 | DNA | Ginkgo Bioworks Holdings, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Coen Steven P. | MA | O | See rema | 3 | S.d | -106 | 14.64 | 0 | -7 |  | 11 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/21/25 16:54 | 10/20/25 | CRBP | Corbus Pharmaceuticals Holdings, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Altmeyer Anne | MA | D |  | 1 | S.d | -22 | 20.50 | 0 | -1 |  | 6 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/21/25 16:05 | 10/20/25 | SLDB | Solid Biosciences Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Brooks Gabriel | MA | O | Chief Me | 1 | S.d | -17 | 5.96 | 0 | -3 |  | 34 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 20:00 | 9/12/25 | BYSI | Beyondspring Inc. |  | Health | Drug | Pharmaceutical Preparations | Decheng Capital China Life Sciences Usd Fund Iii, L.P. | CA | T |  | 17 | S.m | -2,020 | 2.36 | 0 | -855 |  | 4,488 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 19:49 | 10/17/25 | GH | Guardant Health, Inc. | DE | Health | Health | Medical Laboratories | Tariq Musa | CA | D |  | 3 | S.d | -21 | 60.53 | 0 | 0 |  | 8 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 19:48 | 8/19/25 | GH | Guardant Health, Inc. | DE | Health | Health | Medical Laboratories | Potter Myrtle S | CA | D |  | 3 | S.d | -5 | 60.54 | 0 | 0 | 0 | 18 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 19:13 | 10/17/25 | JNJ | Johnson & Johnson | NJ | Health | Drug | Pharmaceutical Preparations | Reed John C | NJ | O | EVP,Inno | 1 | S.d | -4,186 | 192.71 | 0 | -22 |  | 11 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 18:58 | 10/16/25 | LVTX | Lava Therapeutics Nv | P7 | Health | Drug | Pharmaceutical Preparations | Cooperatieve Gilde Healthcare IV U.A. | P7 | T |  | 3 | S.m | -5,141 | 1.48 | 0 | -3,473 |  | 5,294 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 18:00 | 10/15/25 | BGMS | Bio Green Med Solution, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kua Khai Loon | N8 | T |  | 3 | S.m | -815 | 5.03 | 0 | -162 |  | 385 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 17:35 | 8/18/25 | CRSP | Crispr Therapeutics AG | V8 | Health | BioPrd | Biological Products, (No Diag | Kulkarni Samarth | MA | DO | CEO | 3 | S.d | -4,499 | 65.96 | 0 | -68 |  | 340 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 17:20 | 10/16/25 | XGN | Exagen Inc. | DE | Health | Health | Medical Laboratories | Aballi John | CA | DO | P,CEO | 1 | S | -376 | 11.82 | 0 | -32 |  | 755 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 16:42 | 10/17/25 | HIMS | Hims & Hers Health, Inc. | DE | Health | Health | Offices & Clinics of Doctors | Okupe Oluyemi | CA | O | CFO | 7 | S.d | -16,899 | 56.34 | 0 | -300 |  | 137 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 21:00 | 10/15/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Venker Eric | X0 | O | P,Immuno | 5 | S.dm | -53,993 | 15.64 | 0 | -3,453 |  | 1,654 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 20:44 | 10/17/25 | ARTV | Artiva Biotherapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Aslan Fred | CA | DO | P,CEO | 2 | S | -223 | 4.36 | 0 | -51 |  | 382 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 19:55 | 10/15/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | Casdin Partners Master Fund, L.P. | NY | T |  | 3 | S | -44,910 | 25.66 | 0 | -1,750 |  | 7,207 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 19:29 | 10/17/25 | LXEO | Lexeo Therapeutics, Inc. |  | Health | BioPrd | Biological Products, (No Diag | See Tai Sandi | NY | O | Chief De | 2 | S | -37 | 8.56 | 0 | -4 |  | 66 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 19:28 | 10/17/25 | LXEO | Lexeo Therapeutics, Inc. |  | Health | BioPrd | Biological Products, (No Diag | Robertson Jenny | NY | O | GC | 2 | S | -34 | 8.37 | 0 | -4 |  | 69 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 19:28 | 10/17/25 | LXEO | Lexeo Therapeutics, Inc. |  | Health | BioPrd | Biological Products, (No Diag | Otero Jose Manuel | NY | O | Chief Te | 2 | S | -32 | 6.49 | 0 | -5 |  | 64 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 19:26 | 10/17/25 | LXEO | Lexeo Therapeutics, Inc. |  | Health | BioPrd | Biological Products, (No Diag | Adler Eric | NY | O | Chief Me | 2 | S | -33 | 8.29 | 0 | -4 |  | 73 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 19:26 | 10/17/25 | LXEO | Lexeo Therapeutics, Inc. |  | Health | BioPrd | Biological Products, (No Diag | Townsend Richard Nolan | NY | DO | CEO | 3 | S | -135 | 7.97 | 0 | -17 |  | 242 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 17:53 | 10/15/25 | KROS | Keros Therapeutics, Inc. |  | Health | Drug | Pharmaceutical Preparations | Pontifax Management 4 G.P. (2015) Ltd. | L3 | T |  | 1 | S | -84,975 | 17.75 | 0 | -4,787 | -100 | 11 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:41 | 10/15/25 | IRON | Disc Medicine, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bitterman Kevin | MA | D |  | 5 | S.m | -16,488 | 75.48 | 0 | -218 |  | 1,097 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:32 | 8/15/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Porter James Richard | MA | DO | P,CEO | 3 | S.d | -6,618 | 81.71 | 0 | -81 |  | 249 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:31 | 8/7/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Pelish Henry E. | MA | O | Chief Sc | 4 | S.dm | -2,879 | 85.94 | 0 | -34 |  | 66 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:31 | 10/15/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Balcom Alexandra | MA | O | CFO | 4 | S.dm | -7,694 | 86.19 | 0 | -89 |  | 62 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:28 | 10/16/25 | SDGR | Schrodinger, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dugan Margaret | NY | O | Chief Me | 1 | S | -29 | 21.07 | 0 | -1 |  | 25 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:27 | 10/15/25 | RNA | Avidity Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | McCarthy Teresa | CA | O | CHRO | 3 | S.d | -2,090 | 46.44 | 0 | -45 |  | 97 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:15 | 10/16/25 | APLS | Apellis Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Watson David O. | MA | O | GC | 4 | S | -910 | 26.01 | 0 | -35 |  | 204 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:10 | 10/16/25 | PRAX | Praxis Precision Medicines, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Adage Capital Management, L.P. | MA | T |  | 1 | S | -33,198 | 105.76 | 0 | -314 |  | 4,422 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:01 | 10/15/25 | INCY | Incyte Corp | DE | Health | Biolab | Commercial Physical & Biologi | Denton Sheila A. | DE | O | EVP,GC | 6 | S.dm | -519 | 84.67 | 0 | -6 |  | 33 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 15:08 | 8/13/25 | MRAI | Marpai, Inc. | DE | Health | Health | Misc Health & Allied Services | Intelligent Fanatics Capital Management LLC | PA | T |  | 1 | S.m | -271 | 1.44 | 0 | -188 |  | 3,541 | M |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 14:01 | 10/15/25 | AQST | Aquestive Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Jung Cassie | NJ | O | COO | 2 | S.d | -785 | 6.05 | 0 | -130 |  | 285 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 14:01 | 10/15/25 | AQST | Aquestive Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kraus Carl N | NJ | O | Chief Me | 1 | S | -142 | 7.00 | 0 | -20 |  | 282 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 14:00 | 10/15/25 | AQST | Aquestive Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Boyd Peter E. | NJ | O | See Rema | 3 | S | -213 | 6.07 | 0 | -35 |  | 288 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 21:35 | 10/15/25 | GILD | Gilead Sciences, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Dickinson Andrew D | CA | O | CFO | 3 | S | -875 | 116.73 | 0 | -8 |  | 160 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 21:28 | 10/15/25 | GILD | Gilead Sciences, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Mercier Johanna | CA | O | Chief Co | 3 | S.d | -4,014 | 118.06 | 0 | -34 |  | 114 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 20:16 | 10/16/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Swayze Eric | CA | O | EVP Rese | 4 | S.dm | -2,823 | 62.54 | 0 | -45 |  | 37 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 20:16 | 10/15/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Parshall B Lynne | CA | D |  | 3 | S | -1,587 | 52.89 | 0 | -30 |  | 86 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 20:16 | 10/15/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Devers Shannon L. | CA | O | EVP,Chie | 2 | S.dm | -724 | 69.41 | 0 | -10 |  | 17 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 20:15 | 10/14/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Birchler Brian | CA | O | EVP,Corp | 1 | S.dm | -1,724 | 72.13 | 0 | -24 |  | 57 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 18:18 | 10/15/25 | GRAL | Grail, Inc. |  | Health | Health | Medical Laboratories | Ragusa Robert P | CA | DO | CEO | 1 | S | -499 | 68.88 | 0 | -7 |  | 727 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 18:17 | 8/19/25 | GRAL | Grail, Inc. |  | Health | Health | Medical Laboratories | Ofman Joshua J. | CA | O | P | 4 | S.m | -7,017 | 63.64 | 0 | -110 |  | 488 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 17:44 | 10/16/25 | AURA | Aura Biosciences, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Plavsic Mark | MA | O | CTO | 1 | S | -77 | 6.35 | 0 | -12 |  | 197 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 16:41 | 10/15/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cohlhepp Ryan | MA | DO | P,COO | 2 | S.dm | -1,139 | 18.08 | 0 | -63 |  | 203 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 16:35 | 10/14/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | X0 | Health | Drug | Pharmaceutical Preparations | Tessari Eben | X0 | O | COO | 7 | S.dm | -11,865 | 34.97 | 0 | -339 |  | 50 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 16:30 | 10/15/25 | RAPP | Rapport Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bredt David | MA | O | Chief Sc | 3 | S | -552 | 21.66 | 0 | -26 |  | 427 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 16:30 | 9/4/25 | RAPP | Rapport Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ceesay Abraham | MA | DO | CEO | 3 | S | -2,357 | 26.28 | 0 | -90 |  | 722 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 16:21 | 10/7/25 | EBS | Emergent Biosolutions Inc. | DE | Health | Drug | Pharmaceutical Preparations | Glessner Coleen | MD | O | EVP,Qual | 1 | S | -306 | 10.00 | 0 | -31 |  | 144 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 16:15 | 10/16/25 | ABEO | Abeona Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Seshadri Vishwas | OH | DO | CEO | 2 | S.m | -236 | 5.31 | 0 | -45 |  | 1,190 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 16:13 | 8/15/25 | CNTA | Centessa Pharmaceuticals Plc | X0 | Health | Drug | Pharmaceutical Preparations | Hussain Iqbal J | X0 | O | GC | 4 | S.dm | -1,209 | 20.85 | 0 | -58 |  | 111 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 16:01 | 10/14/25 | RCKT | Rocket Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Militello John | NJ | O | See Rema | 3 | S.m | -139 | 3.76 | 0 | -37 |  | 67 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 20:12 | 10/10/25 | APLS | Apellis Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dunlop A. Sinclair | MA | D |  | 3 | S | -2,153 | 23.08 | 0 | -93 |  | 223 | M |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 19:28 | 10/15/25 | ACLX | Arcellx, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Gilson Michelle | CA | O | CFO | 2 | S.m | -1,000 | 88.41 | 0 | -11 |  | 14 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 19:04 | 10/13/25 | MLYS | Mineralys Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Levy Adam Scott | PA | O | CFO,Secr | 1 | S | -452 | 42.01 | 0 | -11 |  | 117 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 19:04 | 10/13/25 | MLYS | Mineralys Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Congleton Jon | PA | DO | CEO | 1 | S | -644 | 42.67 | 0 | -15 |  | 831 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 19:04 | 10/15/25 | MLYS | Mineralys Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Rodman David Malcom | PA | O | Chief Me | 3 | S.d | -1,002 | 30.28 | 0 | -33 |  | 93 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 18:47 | 10/15/25 | ALKS | Alkermes Plc. |  | Health | Drug | Pharmaceutical Preparations | Hopkinson Craig C. | MA | O | EVP R,D, | 1 | S.d | -284 | 31.53 | 0 | -9 |  | 74 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 18:31 | 10/10/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Swisher Daniel N Jr | CA | D |  | 3 | S.d | -511 | 77.43 | 0 | -7 | -100 | 0 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 18:00 | 10/13/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mazumdar Claire | MA | DO | CEO | 1 | S.dm | -467 | 18.88 | 0 | -25 |  | 310 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 17:35 | 10/14/25 | CRSP | Crispr Therapeutics AG | V8 | Health | BioPrd | Biological Products, (No Diag | Kasinger James R. | MA | O | GC,Secre | 1 | S.d | -72 | 66.60 | 0 | -1 |  | 83 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 17:28 | 10/15/25 | KYMR | Kymera Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Gollob Jared | MA | O | Chief Me | 2 | S.d | -3,846 | 61.35 | 0 | -63 |  | 118 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 17:09 | 10/13/25 | RVMD | Revolution Medicines, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Kelsey Stephen Michael | CA | O | See Rema | 3 | S.dm | -7,017 | 45.17 | 0 | -155 |  | 289 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 16:36 | 10/13/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Schundler Russell | NC | O | GC | 2 | S.d | -214 | 24.08 | 0 | -9 |  | 595 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 16:34 | 10/13/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Kaseta Michael | NC | O | CFO,COO | 4 | S.d | -1,429 | 22.77 | 0 | -63 |  | 376 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 16:34 | 10/13/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Moomaw Scott | NC | O | Chief Co | 2 | S.d | -2,138 | 28.29 | 0 | -76 |  | 155 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 16:33 | 10/13/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Saggar Rajeev | NC | O | Chief Me | 2 | S.d | -682 | 26.92 | 0 | -25 |  | 250 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 16:32 | 10/6/25 | SPRB | Spruce Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Parkman Healthcare Partners LLC | CT | T |  | 2 | S | -10 | 19.14 | 0 | -1 |  | 1 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 16:31 | 9/2/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Jeffs Roger | NC | DO | CEO | 4 | S.dm | -13,848 | 106.18 | 0 | -130 |  | 2,752 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 16:30 | 10/13/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Krepp Sarah | NC | O | Chief Hu | 2 | S | -46 | 24.03 | 0 | -2 |  | 143 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 16:15 | 9/3/25 | CGON | Cg Oncology, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Post Leonard E | CA | D |  | 4 | S.d | -307 | 38.35 | 0 | -8 | -100 | 0 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 13:24 | 10/15/25 | KROS | Keros Therapeutics, Inc. |  | Health | Drug | Pharmaceutical Preparations | Adar1 Capital Management, LLC | TX | T |  | 1 | S | -95,659 | 17.75 | 0 | -5,389 | -100 | 0 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 20:11 | 10/10/25 | AKRO | Akero Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cheng Andrew | CA | DO | P,CEO | 3 | S.dm | -4,452 | 48.49 | 0 | -92 |  | 526 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 19:49 | 10/13/25 | ANIP | Ani Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Cook Meredith | MN | O | SVP,GC,S | 3 | S | -111 | 92.46 | 0 | -1 |  | 76 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 17:30 | 9/11/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | Wichterman Troy | WA | O | CFO | 3 | S | -65 | 26.68 | 0 | -2 |  | 185 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 17:30 | 9/11/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | Berard Todd | WA | O | CMO | 4 | S | -282 | 25.62 | 0 | -11 |  | 134 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 17:30 | 10/9/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | Mathew Aby J. | WA | O | EVP,Chie | 3 | S | -44 | 26.55 | 0 | -2 | 0 | 352 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 17:30 | 9/15/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | Aebersold Sarah | WA | O | CHRO | 4 | S | -35 | 26.04 | 0 | -1 |  | 78 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 17:30 | 9/11/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | Foster Karen A. | WA | O | Chief Qu | 3 | S | -36 | 26.57 | 0 | -1 |  | 194 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 16:33 | 10/10/25 | CLPT | Clearpoint Neuro, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Burnett Joseph | CA | DO | CEO,P | 1 | S | -714 | 26.98 | 0 | -26 |  | 228 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 16:31 | 10/9/25 | VSTM | Verastem, Inc. | MA | Health | Drug | Pharmaceutical Preparations | Bunn Paul A. | MA | D |  | 1 | S | -75 | 9.06 | 0 | -8 |  | 8 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 16:17 | 10/10/25 | HIMS | Hims & Hers Health, Inc. | DE | Health | Health | Offices & Clinics of Doctors | Chi Michael | CA | O | Chief Co | 6 | S.dm | -2,893 | 60.60 | 0 | -48 |  | 311 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 16:10 | 10/10/25 | FENC | Fennec Pharmaceuticals Inc. | A1 | Health | BioPrd | Biological Products, (No Diag | Rallis Chris A | NC | D |  | 1 | S.d | -16 | 9.24 | 0 | -2 |  | 57 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 16:01 | 10/10/25 | PTGX | Protagonist Therapeutics, Inc | DE | Health | Drug | Pharmaceutical Preparations | Waddill William D. | CA | D |  | 3 | S.d | -1,473 | 73.67 | 0 | -20 |  | 9 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  |