Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
12/23/25 21:42	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Clark Ian T	CA	D		4	M.d	13,185	22.47	587		10	D
12/23/25 21:42	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Clark Ian T	CA	D		4	S.d	-13,185	22.47	-587		10	D
12/23/25 21:41	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Myles David C.	CA	O	CH. DISC	1	S	-1,554	30.46	-51		711	D
12/23/25 21:40	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zojwalla Naseem	CA	O	Chief Me	2	M.dm	9,195	22.45	410		4	D
12/23/25 21:40	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zojwalla Naseem	CA	O	Chief Me	2	S.dm	-9,195	22.45	-410		4	D
12/23/25 21:05	12/20/25	FDMT	4D Molecular Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Gupta Ashoo	CA	O	VP,Finan	2	M.d	3	2.29	1	3	46	D
12/23/25 21:05	12/20/25	FDMT	4D Molecular Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Gupta Ashoo	CA	O	VP,Finan	2	S.d	-3	2.29	-1		46	D
12/23/25 20:48	12/23/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Firestone Karen	MA	D		1	P	101	12.45	8	15	63	D
12/23/25 20:09	12/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saccomano Nicholas A	CO	DO	P,CEO	1	S	0	2.97	0		7	D
12/23/25 20:08	12/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leverone Jason A.	CO	O	CFO	1	S	-1	2.97	0		16	D
12/23/25 20:00	12/19/25	APGE	Apogee Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Henderson Jane	MA	O	CFO	5	S	-528	70.33	-8		200	D
12/23/25 20:00	10/22/25	ONMD	Onemednet Corp	DE	Health	Biolab	Commercial Physical & Biologi	Green Aaron	MN	DO	CEO	1	S.m	-219	1.73	-126		1,804	D
12/23/25 19:53	12/19/25	LFST	Lifestance Health Group, Inc.	DE	Health	Health	Health Services	Bessler Robert	AZ	D		3	S.m	-1,546	7.03	-220		2,969	I
12/23/25 19:25	12/21/25	GH	Guardant Health, Inc.	DE	Health	Health	Medical Laboratories	Mignone Roberto	CA	D		6	M.d	8,464	25.56	331	121	604	D
12/23/25 18:52	12/22/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ramasastry Saira	CA	D		4	M.d	704	50.29	14		0	D
12/23/25 18:52	12/22/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ramasastry Saira	CA	D		4	S.d	-704	50.29	-14	-100	0	D
12/23/25 18:50	12/19/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Grey Michael G	CA	D		6	M.d	11,540	38.47	300		280	D
12/23/25 18:50	12/19/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Grey Michael G	CA	D		6	S.d	-11,540	38.47	-300		280	D
12/23/25 18:47	12/22/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	3	M.d	107	5.47	20	118	36	D
12/23/25 18:45	12/19/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	4	S	-720	21.19	-34		928	I
12/23/25 18:17	12/19/25	CGEM	Cullinan Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Lynx1 Capital Management LP	PR	T		5	P.m	16,751	6.26	2,675	8	34,194	I
12/23/25 18:01	12/19/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Waddill William D.	CA	D		3	S.d	-1,629	50.34	-32		62	D
12/23/25 18:01	12/19/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vakiener Victoria	CA	D		1	S	-679	67.68	-10		36	D
12/23/25 18:01	12/19/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Anzalone Christopher Richard	CA	DO	CEO	3	S.m	-19,563	66.24	-295		3,917	D
12/23/25 18:01	12/19/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Olukotun Adeoye Y	CA	D		1	S	-677	67.66	-10		34	D
12/23/25 17:33	12/22/25	CRSP	Crispr Therapeutics AG	V8	Health	BioPrd	Biological Products, (No Diag	Prasad Raju	MA	O	CFO	1	S	-560	55.95	-10		7	D
12/23/25 17:00	12/19/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parikh Asit	NJ	D		1	M.d	90	10.30	9	8	122	D
12/23/25 16:58	12/19/25	ULS	Ul Solutions Inc.	DE	Health	Biolab	Testing Laboratories	Ulse Inc.	IL	T		2	S.d	-1,121,250	78.00	-14,375	-100	0	D
12/23/25 16:41	12/22/25	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	Barchas Isaac	WA	D		1	S	-8,330	21.74	-383		4,166	I
12/23/25 16:37	12/19/25	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ugwumba Chidozie	AR	T		2	S.m	-1,790	6.69	-268		393	I
12/23/25 16:35	12/19/25	ENSG	Ensign Group, Inc		Health	Health	Skilled Nursing Care Faciliti	Wittekind Beverly B.	CA	O	VP,GC	4	M.d	2,113	141.84	15	83	33	D
12/23/25 16:35	12/19/25	ENSG	Ensign Group, Inc		Health	Health	Skilled Nursing Care Faciliti	Wittekind Beverly B.	CA	O	VP,GC	4	S.d	-2,113	141.84	-15		33	D
12/23/25 16:33	12/23/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Malcolm Jan	MD	D		2	S	-50	497.55	0		0	D
12/23/25 16:33	12/22/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Sullivan Louis W	MD	D		2	M.d	4,267	358.53	12		3	I
12/23/25 16:33	12/22/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Sullivan Louis W	MD	D		2	S.d	-4,267	358.53	-12		3	I
12/23/25 16:31	12/22/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	5	M.dm	3,018	56.26	54	308	71	D
12/23/25 16:30	12/22/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	12	M.dm	12,700	48.55	262		89	D
12/23/25 16:30	12/23/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Ware J. Anthony	CA	D		1	S	-193	49.58	-4		10	D
12/23/25 16:30	12/19/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	3	M.d	2,995	26.98	111	57	306	D
12/23/25 16:30	12/19/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Horne William B.	GA	D		1	S	-7	2.12	-3	-100	0	D
12/23/25 16:28	12/22/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Lizzul Paul F.	CA	O	Chief Me	2	M.d	103	34.25	3	13	27	D
12/23/25 16:28	12/22/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Lizzul Paul F.	CA	O	Chief Me	2	S.d	-103	34.25	-3		27	D
12/23/25 16:28	12/22/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Mulroy Dennis	CA	O	CFO	4	M.d	1,609	35.18	46		9	D
12/23/25 16:28	12/22/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Mulroy Dennis	CA	O	CFO	4	S.d	-1,609	35.18	-46		9	D
12/23/25 16:27	12/22/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Loumeau Eric J	CA	O	GC	6	M.dm	2,348	29.96	78		9	D
12/23/25 16:27	12/22/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Loumeau Eric J	CA	O	GC	6	S.dm	-2,348	29.96	-78		9	D
12/23/25 16:26	12/22/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	4	M.d	1,365	15.83	86	28	395	D
12/23/25 16:24	12/23/25	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zedelmayer Christine	CA	O	SVP,COO	4	M.dm	284	1.16	244		127	D
12/23/25 16:24	12/23/25	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zedelmayer Christine	CA	O	SVP,COO	4	S.dm	-284	1.16	-244		127	D
12/23/25 16:16	12/19/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Clark David Michael	NJ	O	Chief Pe	4	S	-1,148	11.19	-103		323	D
12/23/25 16:15	12/22/25	HIMS	Hims & Hers Health, Inc.	DE	Health	Health	Offices & Clinics of Doctors	Okupe Oluyemi	CA	O	CFO	10	S.d	-8,708	24.47	-356		125	D
12/23/25 16:13	12/22/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Wierenga Wendell	CA	D		4	M.d	1,775	36.42	49		32	D
12/23/25 16:13	12/22/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Wierenga Wendell	CA	D		4	S.d	-1,775	36.42	-49		32	D
12/23/25 16:11	12/22/25	BCRX	Biocryst Pharmaceuticals Inc	DE	Health	BioPrd	Biological Products, (No Diag	Barnes Alane P	NC	O	GC	4	S.dm	-1,787	6.04	-296		399	D
12/23/25 16:10	12/23/25	ALT	Altimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gill John	MD	D		1	P	51	4.10	13		13	D
12/23/25 16:08	12/22/25	BCRX	Biocryst Pharmaceuticals Inc	DE	Health	BioPrd	Biological Products, (No Diag	Gayer Charles K	NC	O	P,CCO	1	M.d	372	5.01	74	8	953	D
12/23/25 16:08	12/22/25	COO	Cooper Companies, Inc.	DE	Health	OthMd	Ophthalmic Goods	Lucchese Cynthia L	CA	D		1	P	150	84.06	2	23	9	D
12/23/25 16:05	12/22/25	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Green Paula	CA	O	SVP of H	7	S	-624	31.79	-20		168	D
12/23/25 16:05	12/22/25	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Cho Dennis	CA	O	See Rema	7	S	-410	31.53	-13		145	D
12/23/25 16:05	12/22/25	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Leproust Emily M.	CA	DO	CEO	7	S.d	-2,367	31.72	-75		878	D
12/23/25 16:02	12/22/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	8	M.dm	1,424	11.05	129	778	145	D
12/23/25 16:02	12/22/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	8	S.dm	-1,424	11.05	-129		145	D
12/23/25 16:02	12/19/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Desjarlais John R	CA	O	SVP,CSO	2	M.dm	2,150	14.05	153	170	243	D
12/23/25 16:02	12/19/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Desjarlais John R	CA	O	SVP,CSO	2	S.dm	-2,150	14.05	-153		243	D
12/23/25 16:01	12/19/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Dahiyat Bassil I	CA	DO	P,CEO	2	M.dm	3,361	14.04	239	101	477	D
12/23/25 16:01	12/19/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Dahiyat Bassil I	CA	DO	P,CEO	2	S.dm	-3,361	14.04	-239		477	D
12/23/25 14:55	12/19/25	CAPR	Capricor Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunbar George W Jr	CA	D		1	M.d	4	1.39	3	27	14	D
12/23/25 14:04	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	32	M.dm	265	2.04	130		6	D
12/23/25 14:04	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	32	S.dm	-265	2.04	-130		6	D
12/23/25 13:21	12/23/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Freeman Kevin D	GA	D		3	P	59	3.55	17	12	153	D
12/23/25 13:17	12/23/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Eldred Kary	GA	D		2	P	5	3.73	1	2	70	D
12/23/25 10:48	12/22/25	LAKE	Lakeland Industries Inc	DE	Health	Orthop	Orthopedic, Prosthetic & Surg	Yartz Laurel A.	AL	O	CHRO	1	P	11	8.15	1	9	16	D
12/23/25 08:18	12/22/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Stan	IL	D		5	P.dm	152	1.16	130	10	1,435	I
12/23/25 08:16	12/22/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chaouki Steven M	IL	D		1	P.d	50	1.22	41	37	152	D
12/23/25 08:14	12/22/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Louie Ngar Yee	IL	D		1	P.d	100	1.22	82	7	1,249	D
12/23/25 07:25	12/19/25	PLX	Protalix Biotherapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Bashan Dror	L3	DO	P,CEO	1	P	101	1.81	56	2	2,533	D
12/22/25 21:57	12/18/25	MDLN	Medline Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Hellman & Friedman Capital Partners X (Parallel), L.P.	CA	T		1	S.d	-172,717	28.37	-6,088		215,303	I
12/22/25 20:48	12/22/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Kirk Randal J	VA	DT		3	S.m	-26,405	3.96	-6,676		126,913	I
12/22/25 20:46	12/18/25	INCY	Incyte Corp	DE	Health	Biolab	Commercial Physical & Biologi	Tray Thomas	DE	O	Principa	3	S.dm	-681	98.46	-7		24	D
12/22/25 20:46	12/19/25	INCY	Incyte Corp	DE	Health	Biolab	Commercial Physical & Biologi	Tray Thomas	DE	O	Principa	3	M.dm	681	98.46	7	42	24	D
12/22/25 20:45	12/18/25	TIVC	Tivic Health Systems, Inc.	DE	Health	ElcMd	Electromedical & Electrothera	Wolf Lisa G	CA	O	CFO	1	M.d	0	0.00	1		0	D
12/22/25 20:44	12/18/25	TIVC	Tivic Health Systems, Inc.	DE	Health	ElcMd	Electromedical & Electrothera	Ernst Jennifer	CA	DO	CEO	1	M.d	0	0.00	15	82	33	D
12/22/25 20:05	12/19/25	NTRA	Natera, Inc.	DE	Health	Health	Medical Laboratories	Sheena Jonathan	TX	DH	CO-FOUND	10	S.dm	-6,868	186.08	-37		292	I
12/22/25 19:45	12/18/25	BNTC	Benitec Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Suvretta Capital Management, LLC	NY	DT		2	P.m	20,539	13.45	1,528	511	1,827	I
12/22/25 18:57	12/18/25	ALLO	Allogene Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Kazam Joshua A	CA	D		1	M.d	0	0.00	48	16	351	D
12/22/25 18:55	12/19/25	ICU	Seastar Medical Holding Corp	CO	Health	MdEq	Surgical & Medical Instrument	Baird Jennifer A	C0	D		1	P	1	0.2350	4	13	36	D
12/22/25 17:52	12/22/25	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	Galbraith Kenneth	DE	DO	Chair,CE	2	M.d	1,284	8.71	148		133	D
12/22/25 17:52	12/22/25	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	Galbraith Kenneth	DE	DO	Chair,CE	2	S.d	-1,284	8.71	-148		133	D
12/22/25 17:44	12/17/25	ZIVO	Zivo Bioscience, Inc.	NV	Health	BioPrd	Biological Products, (No Diag	Strome Mark E	FL	T		2	S.d	-1,145	4.24	-270		3,353	I
12/22/25 17:26	12/18/25	MDLN	Medline Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Gic Private Ltd	U0	T		2	S	-654,480	28.72	-22,791		118,797	M
12/22/25 17:26	12/18/25	MDLN	Medline Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Gic Private Ltd	U0	T		2	P	654,480	28.72	22,791	24	118,797	M
12/22/25 17:15	12/18/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Genmab A/S	G7	T		2	P.m	53,349	97.00	550	1	72,013	I
12/22/25 17:00	12/19/25	CGEM	Cullinan Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Michaelson Jennifer	MA	O	Chief Sc	4	S.m	-129	11.34	-11		138	D
12/22/25 16:30	12/18/25	MDLN	Medline Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Tc Group VII S1, L.L.C.	DC	T		1	S.d	-554,954	29.00	-19,136		215,303	I
12/22/25 16:30	12/18/25	MDLN	Medline Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Carlyle Mozart Coinvestment Holdings, L.P.	DC	T		1	S.d	-554,954	29.00	-19,136		215,303	I
12/22/25 16:30	12/18/25	MDLN	Medline Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Mills Andrew J.	IL	D		1	P.d	75,000	29.00	2,586	999%	2,617	I
12/22/25 16:30	12/18/25	MDLN	Medline Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Mills Charles N.	IL	D		1	P.d	74,800	29.00	2,579	999%	2,643	I
12/22/25 16:15	12/19/25	TDOC	Teladoc Health, Inc.	DE	Health	Health	Offices & Clinics of Doctors	Evans Jason Eric	NY	D		1	M.d	0	0.00	1	12	9	D
12/22/25 16:15	12/18/25	LITS	Lite Strategy, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schornstein Alexander	2M	T		1	S	-946	1.37	-691		3,675	D
12/22/25 16:10	12/22/25	ALT	Altimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Durso Jerome Benedict	MD	D		1	P	52	4.13	13		13	D
12/22/25 16:10	12/22/25	IRMD	Iradimed Corp	DE	Health	MdEq	Surgical & Medical Instrument	Susi Roger E.	FL	DOT	CEO,P,CB	13	S	-5,463	84.04	-65		4,573	I
12/22/25 16:09	12/19/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Urist Marshall	NY	O	EVP,Rese	4	S	-4,821	39.15	-123		228	I
12/22/25 16:04	12/19/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mottola Frank	MD	O	SVP,Chie	2	M.d	1,585	39.62	40		15	D
12/22/25 16:04	12/19/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mottola Frank	MD	O	SVP,Chie	2	S.d	-1,585	39.62	-40		15	D
12/22/25 16:00	12/19/25	LITS	Lite Strategy, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flynn James P	CA	D		2	P	120	1.47	82	459	100	D
12/22/25 11:53	12/17/25	AURX	Nuo Therapeutics, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Winzer C Eric	TX	D		1	M.d	28	0.4000	69	66	173	D
12/22/25 11:43	12/18/25	KYTX	Kyverna Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Seidenberg Beth C	CA	D		1	P	1,000	7.50	133	3	4,674	I
12/22/25 11:42	12/18/25	KYTX	Kyverna Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Westlake Biopartners Opportunity Fund I, L.P.	CA	T		1	P	1,000	7.50	133	3	4,657	I
12/22/25 08:15	12/18/25	HYPD	Hyperion Defi, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Strahlman Ellen R	CA	D		1	P	121	3.14	38	29	171	M
12/22/25 07:38	12/19/25	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	Siegall Clay B	WA	DO	P,CEO	2	P	1,149	21.36	54	7	853	D
12/22/25 07:32	12/19/25	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tsai Philip	WA	O	Chief Te	1	P	205	20.49	10	30	43	D
12/22/25 07:07	12/19/25	EVMN	Evommune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hopfner Robert Lorne	CA	DT		1	P	17	17.35	1	0	3,372	I
12/22/25 07:00	12/18/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bagai Shaun	CA	DO	CEO	2	P	9	0.8769	10	3	340	D
12/19/25 21:30	12/18/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Todisco Joseph	NJ	DO	CEO	2	M.d	493	8.22	60	13	509	D
12/19/25 21:30	12/18/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Todisco Joseph	NJ	DO	CEO	2	S.d	-493	8.22	-60		509	D
12/19/25 21:04	12/17/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Sukhatme Mayukh	X0	DO	P,CIO	2	M.d	1,374	15.91	86	0	18,837	D
12/19/25 21:04	12/17/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Sukhatme Mayukh	X0	DO	P,CIO	2	S.d	-1,374	15.91	-86	0	18,837	D
12/19/25 21:00	12/19/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	More Robert J	CA	D		2	S	-5,250	20.44	-257		3,833	I
12/19/25 20:00	12/17/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Castagna Michael	CT	DO	CEO	6	M.dm	2,231	5.17	432	21	2,505	D
12/19/25 20:00	12/17/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Castagna Michael	CT	DO	CEO	6	S.dm	-2,231	5.17	-432		2,505	D
12/19/25 19:29	12/17/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		4	S.m	-11,418	1.87	-6,110		15,993	I
12/19/25 19:24	12/17/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Thompson Peter A.	MA	D		2	S.m	-4,898	44.55	-110		3,597	I
12/19/25 19:21	12/17/25	HYPD	Hyperion Defi, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Walters Happy David	CA	D		1	P	187	3.02	62	124	112	D
12/19/25 19:17	12/18/25	STME	Stimcell Energetics Inc.	NV	Health	MdEq	Surgical & Medical Instrument	Vahabzadeh Amir	A1	DT		1	S	-6	0.3400	-17	0	4,165	D
12/19/25 18:16	12/19/25	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	Quisel John D	MA	DO	CEO	3	M.d	4,129	44.73	92	101	184	D
12/19/25 17:58	12/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kunkel Lori Anne	CO	D		3	M.d	118	3.74	31	27	146	D
12/19/25 17:39	11/1/25	HALO	Halozyme Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Caudill Cortney	CA	O	SVP,COO	2	M.d	278	20.45	14		13	D
12/19/25 17:39	11/1/25	HALO	Halozyme Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Caudill Cortney	CA	O	SVP,COO	2	S.d	-278	20.45	-14		13	D
12/19/25 17:38	9/3/25	TNON	Tenon Medical, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Williamson Kevin	CA	DO	CFO	1	M.d	0	0.00	2		2	D
12/19/25 17:38	12/19/25	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goncalves Joana	CA	O	Chief Me	2	M.d	266	18.97	14		2	D
12/19/25 17:38	12/19/25	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goncalves Joana	CA	O	Chief Me	2	S.d	-266	18.97	-14		2	D
12/19/25 17:25	12/18/25	SIBN	Si-Bone, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Pisetsky Michael A.	CA	O	SVP,Ops,	4	S	-505	19.11	-26		255	D
12/19/25 17:24	12/17/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Lloyd George W.	NY	O	EVP,Inve	3	S.m	-13,808	38.85	-355		1,000	I
12/19/25 17:24	12/18/25	SIBN	Si-Bone, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Maheshwari Anshul	CA	O	CFO	5	S.m	-555	18.98	-29		211	D
12/19/25 17:17	12/19/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Johnson John	IL	D		3	S.dm	-2,496	12.41	-201		698	D
12/19/25 17:10	12/17/25	BEAT	Heartbeam, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	De Urioste George	CA	D		1	S.m	-182	3.19	-57	-100	0	D
12/19/25 17:04	12/19/25	RXRX	Recursion Pharmaceuticals, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Gibson Christopher	UT	DO	CEO	6	S.d	-1,914	5.32	-360		954	D
12/19/25 17:00	12/18/25	IQV	Iqvia Holdings Inc.	DE	Health	Biolab	Commercial Physical & Biologi	Bousbib Ari	NC	DO	See Rema	4	M.d	28,237	127.93	221	20	1,350	D
12/19/25 17:00	12/18/25	IQV	Iqvia Holdings Inc.	DE	Health	Biolab	Commercial Physical & Biologi	Bousbib Ari	NC	DO	See Rema	4	S.d	-28,237	127.93	-221		1,350	D
12/19/25 17:00	12/19/25	SVRA	Savara Inc	DE	Health	Drug	Pharmaceutical Preparations	Ramsay David A	PA	D		1	S	-121	6.06	-20		2,534	D
12/19/25 17:00	12/18/25	CGEM	Cullinan Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Sumer Jacquelyn L	MA	O	GC	1	S	-34	9.67	-3		135	D
12/19/25 17:00	12/18/25	CGEM	Cullinan Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Jones Jeffrey Alan	MA	O	Chief Me	1	S	-45	9.67	-5		170	D
12/19/25 17:00	12/17/25	ADTX	Aditxt, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brady Brian Michael	CA	D		1	S	0	2.00	0		0	D
12/19/25 16:59	12/17/25	ELUT	Elutia Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Rakin Kevin	CT	DT		1	P	26	0.5199	50	1	5,155	I
12/19/25 16:49	12/17/25	LFST	Lifestance Health Group, Inc.	DE	Health	Health	Health Services	Varanakis Ann	AZ	O	Chief Pe	1	S	-345	6.90	-50		316	D
12/19/25 16:47	12/18/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Davis Krista	MN	O	SVP,CHRO	1	S	-134	82.40	-2		59	D
12/19/25 16:31	12/18/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Thompson Tommy G	MD	D		2	M.d	548	301.19	2	9	22	D
12/19/25 16:31	12/18/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Thompson Tommy G	MD	D		2	S.d	-548	301.19	-2		22	D
12/19/25 16:30	12/17/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	60	M.edm	138,795	286.77	484	302	644	D
12/19/25 16:30	12/17/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	60	S.edm	-138,795	286.77	-484		644	D
12/19/25 16:30	12/18/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burrows Francis	CA	O	Chief Sc	2	M.d	400	6.81	59		34	D
12/19/25 16:30	12/18/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burrows Francis	CA	O	Chief Sc	2	S.d	-400	6.81	-59		34	D
12/19/25 16:18	12/18/25	COO	Cooper Companies, Inc.	DE	Health	OthMd	Ophthalmic Goods	Rivas Maria	CA	D		1	P	82	82.13	1	10	11	I
12/19/25 16:15	12/17/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mohan Raju	CA	DO	CEO,P	2	M.d	365	2.23	164	7	2,373	D
12/19/25 16:15	12/18/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mohan Raju	CA	DO	CEO,P	2	S.d	-365	2.23	-164		2,373	D
12/19/25 16:15	12/17/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nuss John	CA	O	Chief Sc	2	M.d	98	2.06	48	11	489	D
12/19/25 16:15	12/18/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nuss John	CA	O	Chief Sc	2	S.d	-98	2.06	-48		489	D
12/19/25 16:12	12/18/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	4	M.d	4,520	105.62	43	8	588	D
12/19/25 16:12	12/18/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	4	S.d	-4,520	105.62	-43		588	D
12/19/25 16:10	12/16/25	FDMT	4D Molecular Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Bizily Scott	CA	O	GC	9	M.d	135	8.47	16		5	D
12/19/25 16:10	12/16/25	FDMT	4D Molecular Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Bizily Scott	CA	O	GC	9	S.d	-135	8.47	-16		5	D
12/19/25 16:08	12/17/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Lewis Joel	GA	DO	P,CEO	10	M.dm	418	4.35	96	13	835	D
12/19/25 16:08	12/17/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Lewis Joel	GA	DO	P,CEO	10	S.dm	-418	4.35	-96		835	D
12/19/25 16:06	12/17/25	CSTL	Castle Biosciences Inc	DE	Health	Health	Medical Laboratories	Maetzold Derek J	TX	DO	P,Chief	11	S.dm	-2,246	20.44	-110		329	D
12/19/25 16:06	12/17/25	CSTL	Castle Biosciences Inc	DE	Health	Health	Medical Laboratories	Oelschlager Kristen M	TX	O	COO	5	S.adm	-1,958	22.60	-87		154	D
12/19/25 16:06	12/17/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Jamil Khurram	GA	O	Chief Me	4	S.d	-1,050	4.12	-255		4	D
12/19/25 16:06	12/17/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Jamil Khurram	GA	O	Chief Me	4	M.d	1,050	4.12	255		4	D
12/19/25 16:06	12/18/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	T		5	P.m	235,171	42.36	5,552	21	31,431	I
12/19/25 16:05	12/18/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bhatt Padmanabh P.	MD	O	SVP of I	2	M.d	32	14.28	2	18	15	D
12/19/25 16:05	12/18/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bhatt Padmanabh P.	MD	O	SVP of I	2	S.d	-32	14.28	-2		15	D
12/19/25 16:05	12/18/25	IMVT	Immunovant, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Van Tuyl Christopher	NY	O	GC	1	S	-291	26.91	-11		150	D
12/19/25 16:05	12/17/25	SLGL	Sol-Gel Technologies Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		7	P.m	685	37.14	18	1	1,366	I
12/19/25 16:05	12/17/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Goin Kathleen	PA	O	COO	4	M.d	856	49.73	17		0	D
12/19/25 16:05	12/17/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Goin Kathleen	PA	O	COO	4	S.d	-856	49.73	-17	-100	0	D
12/19/25 16:05	12/17/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Shlevin Harold H.	GA	D		6	M.dm	1,953	4.35	448		31	D
12/19/25 16:05	12/17/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Shlevin Harold H.	GA	D		6	S.dm	-1,953	4.35	-448		31	D
12/19/25 16:04	12/17/25	DBVT	Dbv Technologies S.A.	I0	Health	BioPrd	Biological Products, (No Diag	Epic Bpifrance	I0	H	Member o	1	S.m	-15,484	4.60	-3,369		7,530	I
12/19/25 15:43	12/18/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Klausner Arthur J	IL	D		1	S	-344	67.15	-5		9	D
12/19/25 15:29	12/19/25	LAKE	Lakeland Industries Inc	DE	Health	Orthop	Orthopedic, Prosthetic & Surg	Jenkins James M.	AL	DO	P,CEO,Ex	1	P	10	7.92	1	1	94	D
12/19/25 11:53	12/17/25	LUCY	Innovative Eyewear Inc	FL	Health	OthMd	Ophthalmic Goods	Galkin Vladimir	FL	T		3	P.m	110	1.48	74	8	997	D
12/19/25 11:00	12/17/25	HYPD	Hyperion Defi, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Geltzeiler Michael S	CA	D		1	P	90	3.01	30	52	88	D
12/19/25 06:05	12/18/25	GLSI	Greenwich Lifesciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Snehal	TX	DOT	CEO,CFO	4	P	201	9.30	22	0	5,592	D
12/18/25 20:05	12/16/25	SRPT	Sarepta Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Estepan Ian Michael	MA	O	COO	1	S	-294	22.31	-13		193	D
12/18/25 19:54	12/16/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Gold Daniel Allen	X0	D		2	S.m	-65,370	21.83	-2,995		18,048	I
12/18/25 19:52	12/16/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Manchester Keith S	X0	D		2	S.m	-65,370	21.83	-2,995		18,048	I
12/18/25 19:41	12/16/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Qvt Financial LP	NY	H	Director	2	S.m	-65,370	21.83	-2,995		18,048	I
12/18/25 19:30	12/16/25	ATEC	Alphatec Holdings, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Lish Scott	CA	O	COO	5	S.d	-1,255	13.32	-94		672	D
12/18/25 19:28	12/16/25	ATEC	Alphatec Holdings, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Pelizzon David R	CA	D		4	S.m	-20,565	20.57	-1,000		11,492	I
12/18/25 18:54	9/26/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Struthers Richard Scott	CA	DO	P,CEO	2	S.d	-766	15.71	-49		1,343	I
12/18/25 18:34	12/17/25	GH	Guardant Health, Inc.	DE	Health	Health	Medical Laboratories	Hidalgo Medina Manuel	CA	D		7	M.d	339	62.27	5		1	D
12/18/25 18:33	12/17/25	GH	Guardant Health, Inc.	DE	Health	Health	Medical Laboratories	Tariq Musa	CA	D		6	S.d	-31	27.96	-1		8	D
12/18/25 18:30	12/16/25	AVR	Anteris Technologies Global Corp.	DE	Health	Orthop	Orthopedic, Prosthetic & Surg	St Denis David	C3	DO	COO	1	M.d	0	0.00	167		101	D
12/18/25 18:30	12/16/25	AVR	Anteris Technologies Global Corp.	DE	Health	Orthop	Orthopedic, Prosthetic & Surg	McDonnell Matthew	C3	O	CFO	1	M.d	0	0.00	28		28	I
12/18/25 18:30	12/16/25	AVR	Anteris Technologies Global Corp.	DE	Health	Orthop	Orthopedic, Prosthetic & Surg	Paterson Wayne	C3	DO	CEO	1	M.d	0	0.00	333		203	I
12/18/25 18:30	12/16/25	AVR	Anteris Technologies Global Corp.	DE	Health	Orthop	Orthopedic, Prosthetic & Surg	Seaberg John D	C3	D		1	M.d	0	0.00	28	141	47	D
12/18/25 18:14	12/17/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		5	S.dm	-31,380	83.58	-375		972	I
12/18/25 18:10	12/16/25	SGHT	Sight Sciences, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Encrantz Staffan	CA	DT		1	P	116	8.31	14	0	7,111	D
12/18/25 18:08	12/18/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ring Christine	CA	O	GC	6	M.d	833	8.59	97		51	D
12/18/25 18:08	12/18/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ring Christine	CA	O	GC	6	S.d	-833	8.59	-97		51	D
12/18/25 18:02	12/16/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazumdar Claire	MA	DO	CEO	7	M.dm	2,199	10.50	210	161	339	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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