Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
8/19/25 20:00	8/15/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Tan Aik Na	MA	D		S.d	-194	9.25	-21	-34	40	D
8/19/25 19:40	8/18/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Trimarchi Thomas	CA	O	P,CFO	S	-872	50.23	-17	-4	463	D
8/19/25 19:40	8/18/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	York Charles N II	CA	O	COO,CFO	S.d	-28	6.77	-4	-1	278	D
8/19/25 19:38	8/18/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dubow Adam	CA	O	GC,Secre	S.d	-30	6.77	-4	-7	55	D
8/19/25 19:37	8/18/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bender Jeremy	CA	DO	CEO	S.d	-109	6.77	-16	-1	1,770	D
8/19/25 19:36	8/18/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Merendino Lauren	CA	O	Chief Co	S.d	-25	6.77	-4	-8	42	D
8/19/25 19:07	8/15/25	ADAP	Adaptimmune Therapeutics Plc	X0	Health	BioPrd	Biological Products, (No Diag	Behbahani Ali	CA	D		S.m	-229	0.0118	-19,500	-100	0	I
8/19/25 18:22	8/18/25	RXRX	Recursion Pharmaceuticals, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Khan Najat	UT	DO	Chief R,	S	-202	5.52	-37	-5	668	D
8/19/25 18:00	8/18/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Schneyer Mark C.	CA	O	EVP,CFO	S	-554	25.18	-22	-35	40	D
8/19/25 17:28	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Garg Pushkal	MA	O	EVP Chie	S.m	-1,300	455.89	-3	-12	21	D
8/19/25 17:28	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Tanguler Tolga	MA	O	EVP,Chie	S	-633	453.27	-1	-5	29	D
8/19/25 17:27	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Poulton Jeffrey V.	MA	O	EVP,CFO	S	-1,031	453.27	-2	-4	50	D
8/19/25 17:27	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Greenstreet Yvonne	MA	DO	CEO	S	-3,163	453.27	-7	-11	57	D
8/19/25 17:26	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Fitzgerald Kevin Joseph	MA	O	CSO,EVP,	S	-633	453.27	-1	-6	23	D
8/19/25 17:26	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Bonney Michael W	MA	D		S.d	-5,063	450.00	-11	-35	21	D
8/19/25 17:10	8/15/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Santini Gino	MA	D		S.d	-201	37.19	-5	-5	95	D
8/19/25 16:51	8/15/25	LENZ	Lenz Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Versant Venture Capital Vi, L.P.	CA	T		S.m	-10,255	39.34	-261	-8	3,205	M
8/19/25 16:47	8/15/25	DGX	Quest Diagnostics Inc	DE	Health	Health	Medical Laboratories	Plewman Patrick	NJ	O	SVP for	S	-356	180.00	-2	-10	17	D
8/19/25 16:40	8/18/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	S	-139	27.80	-5	-2	204	D
8/19/25 16:40	8/18/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Smiley Joshua L	MA	O	See Rema	S.d	-241	36.24	-7	-8	77	D
8/19/25 16:40	8/18/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Edmondson Frazor Titus III	MA	O	GC	S.d	-68	36.24	-2	-4	42	D
8/19/25 16:37	8/19/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	S.d	-77	38.31	-2	-1	141	D
8/19/25 16:30	8/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	S.d	-2,036	75.42	-27	-10	249	D
8/19/25 16:30	8/15/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	S	-524	26.18	-20	-5	356	D
8/19/25 16:30	8/18/25	SRRK	Scholar Rock Holding Corp	DE	Health	BioPrd	Biological Products, (No Diag	Parlavecchio Caryn	MA	O	CHRO	S	-68	31.17	-2	-1	155	D
8/19/25 16:30	8/18/25	CRSP	Crispr Therapeutics AG	V8	Health	BioPrd	Biological Products, (No Diag	Kulkarni Samarth	MA	DO	CEO	S.d	-761	58.15	-13	-4	293	D
8/19/25 16:27	8/18/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yea Christopher	MA	O	Chief De	S.d	-35	13.19	-3	-2	129	D
8/19/25 16:26	8/18/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Audhya Paul K.	MA	O	Chief Me	S.d	-39	13.19	-3	-2	117	D
8/19/25 16:26	8/18/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	S.d	-58	13.19	-4	-1	375	D
8/19/25 16:24	8/15/25	ENSG	Ensign Group, Inc		Health	Health	Skilled Nursing Care Faciliti	Shaw Daren	CA	D		S	-166	166.17	-1	-4	25	D
8/19/25 16:15	8/15/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kapadia Sandip	PA	O	CFO	S	-787	36.50	-22	-100	0	D
8/19/25 16:13	8/15/25	INCY	Incyte Corp	DE	Health	Biolab	Commercial Physical & Biologi	Denton Sheila A.	DE	O	EVP,GC	S.d	-24	86.81	0	-1	33	D
8/19/25 16:12	8/15/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	Pinto Shelly	CA	O	SVP,Fina	S	0	0.6404	-1	-1	89	D
8/19/25 16:09	8/15/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	Lettmann Jason	CA	DO	CEO	S	-2	0.6404	-2	-1	213	D
8/19/25 16:08	8/18/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shaff Eric D.	MA	D		S.d	-4	16.65	0	-2	11	D
8/19/25 16:07	8/18/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Desrosier Thomas	MA	O	See Rema	S.d	-1	16.65	0	-1	7	D
8/19/25 16:07	8/18/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Henn Matthew R	MA	O	See Rema	S.d	-1	16.65	0	-2	5	D
8/19/25 16:06	8/18/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Teresa L.	MA	O	See Rema	S.d	-1	16.65	0	-1	5	D
8/19/25 16:04	8/15/25	CSTL	Castle Biosciences Inc	DE	Health	Health	Medical Laboratories	Maetzold Derek J	TX	DO	P,Chief	S	-27	20.04	-1	0	330	D
8/19/25 13:10	8/18/25	RMD	Resmed Inc	DE	Health	MdEq	Surgical & Medical Instrument	Hernandez John	CA	D		S.d	-739	287.10	-3	-39	4	D
8/19/25 11:28	8/15/25	AORT	Artivion, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Mackin James P	GA	O	P,CEO	S	-529	42.32	-13	-1	853	D
8/18/25 21:00	8/18/25	TNYA	Tenaya Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Higa Tomohiro	CA	O	SVP,Fina	S	-4	1.25	-3	-3	95	D
8/18/25 20:59	8/18/25	TNYA	Tenaya Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Tingley Whittemore	CA	O	Chief Me	S	-6	1.25	-5	-3	173	D
8/18/25 20:58	8/18/25	TNYA	Tenaya Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Ali Faraz	CA	DO	CEO	S	-18	1.25	-15	-5	303	D
8/18/25 20:56	8/15/25	GILD	Gilead Sciences, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Mercier Johanna	CA	O	Chief Co	S.d	-3,319	118.53	-28	-20	114	D
8/18/25 20:15	8/15/25	ARTV	Artiva Biotherapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Aslan Fred	CA	DO	P,CEO	S	-70	2.73	-26	-6	382	D
8/18/25 19:34	8/15/25	GILD	Gilead Sciences, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Dickinson Andrew D	CA	O	CFO	S	-296	118.53	-3	-2	160	D
8/18/25 18:19	8/15/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Wolk Joseph J	NJ	O	EVP,CFO	S.d	-2,976	176.91	-17	-17	85	D
8/18/25 18:11	8/18/25	EW	Edwards Lifesciences Corp	DE	Health	Orthop	Orthopedic, Prosthetic & Surg	Wood Larry L	CA	O	Global P	S.d	-699	78.06	-9	-4	207	D
8/18/25 17:56	8/15/25	DXCM	Dexcom Inc	DE	Health	MdEq	Surgical & Medical Instrument	Brown Michael Jon	CA	O	EVP,GC	S	-40	80.29	-1	-1	94	D
8/18/25 17:53	8/15/25	DXCM	Dexcom Inc	DE	Health	MdEq	Surgical & Medical Instrument	Foletta Mark G	CA	D		S	-223	81.06	-3	-5	57	I
8/18/25 17:33	8/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kelley Shannon T	PA	O	GC	S	-480	367.81	-1	-12	9	D
8/18/25 17:23	8/18/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Leonard Matthew J	MN	D		S	-612	88.17	-7	-42	9	D
8/18/25 17:14	8/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	S	-127	15.00	-9	-2	427	D
8/18/25 17:02	8/15/25	SOLV	Solventum Corp	DE	Health	MdEq	Surgical & Medical Instrument	3M Co	MN	T		S	-646,360	73.45	-8,800	-26	25,569	D
8/18/25 17:02	8/14/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Podlesak Dennis	NY	D		S.dm	-875	15.19	-58	-23	192	D
8/18/25 16:35	8/14/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schwartz Jonathan David	NJ	O	See Rema	S	-34	3.02	-11	-5	224	D
8/18/25 16:35	8/14/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Militello John	NJ	O	See Rema	S	-21	3.02	-7	-11	57	D
8/18/25 16:35	8/14/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Martin	NJ	O	GC	S	-37	3.02	-12	-8	137	D
8/18/25 16:34	8/15/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Walsh Patrick D	MN	D		S	-801	89.05	-9	-11	70	D
8/18/25 16:34	8/18/25	AURA	Aura Biosciences, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Elazzouzi Amy	MA	O	SVP,Fina	S.d	-52	6.70	-8	-8	87	D
8/18/25 16:33	8/15/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zoon Kathryn C	MD	D		S	-63	8.87	-7	-9	72	D
8/18/25 16:32	8/14/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Shanmugam Muthusamy	MN	DO	HEAD OF	S.m	-8,825	88.25	-100	-14	630	I
8/18/25 16:31	8/14/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sensenig Bethany	MD	D		S	-227	42.25	-5	-100	0	D
8/18/25 16:29	8/15/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	S.d	-51	35.42	-1	-8	17	D
8/18/25 16:29	8/15/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Gassert Chad	MN	O	SVP - CO	S	-1,739	86.97	-20	-7	247	I
8/18/25 16:28	8/14/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hudson Frederick M.	MD	D		S	-315	42.26	-7	-14	46	D
8/18/25 16:19	8/14/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Schaeffer Orlov S Nicole	NJ	O	Chief Pe	S	-1,273	127.34	-10	-11	80	D
8/18/25 16:10	8/18/25	HYPR	Hyperfine, Inc.	DE	Health	ElcMd	Electromedical & Electrothera	Teisseyre Thomas	CT	O	COO	S	-2	1.33	-1	0	381	D
8/18/25 16:05	8/15/25	OM	Outset Medical, Inc.	DE	Health	ElcMd	Electromedical & Electrothera	Trigg Leslie	CA	DO	Chair,CE	S	-12	12.88	-1	-1	165	D
8/18/25 16:01	8/15/25	OM	Outset Medical, Inc.	DE	Health	ElcMd	Electromedical & Electrothera	Nash Marc	CA	O	SVP Oper	S	-3	12.88	0	-1	43	D
8/18/25 16:00	8/15/25	OM	Outset Medical, Inc.	DE	Health	ElcMd	Electromedical & Electrothera	Brottem John L.	CA	O	GC	S	-5	12.88	0	-1	47	D
8/15/25 21:35	8/14/25	NTRA	Natera, Inc.	DE	Health	Health	Medical Laboratories	Moshkevich Solomon	TX	O	P,CLINIC	S	-136	155.46	-1	-1	124	D
8/15/25 21:35	8/14/25	NTRA	Natera, Inc.	DE	Health	Health	Medical Laboratories	Fesko John	TX	O	P,CHIEF	S	-105	155.46	-1	0	153	D
8/15/25 21:00	8/15/25	ADMA	Adma Biologics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Grossman Adam S	NJ	DO	P,CEO	S.d	-354	16.88	-21	-1	3,756	D
8/15/25 19:49	8/13/25	PEN	Penumbra Inc	DE	Health	MdEq	Surgical & Medical Instrument	Yuen Maggie	CA	O	CFO	S.d	-500	250.00	-2	-13	14	D
8/15/25 19:44	8/13/25	PEN	Penumbra Inc	DE	Health	MdEq	Surgical & Medical Instrument	Bose Arani	CA	D		S	-3,008	250.65	-12	-4	291	D
8/15/25 19:23	8/13/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		S.m	-1,966	61.11	-32	-3	1,064	I
8/15/25 19:11	8/14/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		S.m	-10	2.00	-5	0	4,483	I
8/15/25 18:31	8/11/25	SGRY	Surgery Partners, Inc.	DE	Health	Health	General Medical & Surgical Ho	Maryland Patricia Anne	TN	D		S.a	0	0.00	0	0	25	D
8/15/25 18:31	8/11/25	SGRY	Surgery Partners, Inc.	DE	Health	Health	General Medical & Surgical Ho	Deluca Teresa	TN	D		S	-455	22.74	-20	-31	45	D
8/15/25 18:13	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	S.d	-103	17.23	-6	-5	111	D
8/15/25 18:04	8/15/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bate Kenneth	PA	D		S.d	-3,652	365.20	-10	-79	3	D
8/15/25 17:59	8/13/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hamilton James C	CA	O	Chief Me	S.m	-200	20.00	-10	-4	262	D
8/15/25 17:50	8/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Teresa	CA	O	CHRO	S.d	-466	46.56	-10	-9	97	D
8/15/25 17:42	8/13/25	ATEC	Alphatec Holdings, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Lish Scott	CA	O	COO	S	-149	16.00	-9	-1	665	D
8/15/25 17:08	8/13/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Dreyer Scott	MA	O	EVP,Chie	S.d	-185	38.03	-5	-4	104	D
8/15/25 16:57	8/13/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Johnson John	IL	D		S	-786	7.32	-108	-11	833	D
8/15/25 16:40	8/13/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wu Xiaobin	V8	O	P,COO	S.dm	-27,348	304.56	-90	-7	1,245	D
8/15/25 16:38	8/13/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	S.d	-3,309	300.45	-11	-4	252	D
8/15/25 16:33	8/13/25	LNTH	Lantheus Holdings, Inc.	DE	Health	Diagn	In Vitro & In Vivo Diagnostic	Blanchfield Paul	MA	O	P	S	-164	53.57	-3	-3	108	D
8/15/25 16:31	8/14/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Shah Nikita	NJ	O	EVP	S	-666	9.29	-72	-21	267	D
8/15/25 16:31	8/13/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Allan Jonathan	MA	O	GC,Corp	S	-206	15.00	-14	-41	20	D
8/15/25 16:30	8/13/25	ADUS	Addus Homecare Corp	DE	Health	Health	Home Health Care Services	Bickham W Bradley	TX	O	P,COO	S	-1,038	115.34	-9	-18	42	D
8/15/25 16:30	8/14/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Crombez Eric	OH	D		S	-33	6.93	-5	-10	42	D
8/15/25 16:30	8/15/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vazzano Joseph Walter	OH	O	CFO	S	-110	7.36	-15	-3	463	D
8/15/25 16:30	8/13/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Konidaris Tasos	NJ	O	EVP,CFO	S.m	-4,663	9.33	-500	-80	122	D
8/15/25 16:23	8/15/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	S	-192	38.42	-5	-1	387	D
8/15/25 16:18	8/13/25	HIMS	Hims & Hers Health, Inc.	DE	Health	Health	Offices & Clinics of Doctors	Okupe Oluyemi	CA	O	CFO	S.d	-556	48.05	-12	-9	125	D
8/15/25 16:14	8/13/25	CSTL	Castle Biosciences Inc	DE	Health	Health	Medical Laboratories	Maetzold Derek J	TX	DO	P,Chief	S	-839	19.50	-43	-12	331	D
8/15/25 16:12	8/13/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Rubric Capital Management LP	NY	T		S	-946	37.85	-25	-1	3,133	I
8/15/25 16:09	8/6/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Maclean Michael F	CA	O	CFO	S	-1,321	42.73	-31	-32	66	D
8/15/25 16:07	8/13/25	CLDX	Celldex Therapeutics, Inc.	DE	Health	Diagn	In Vitro & In Vivo Diagnostic	Jimenez Freddy A.	NJ	O	SVP,GC	S	-19	24.77	-1	-2	35	D
8/15/25 16:07	8/13/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	S.d	-72	46.66	-2	-4	39	D
8/15/25 16:05	8/14/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Ausiello Dennis A	MA	D		S.d	-13,730	436.58	-31	-88	4	D
8/15/25 12:45	8/13/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	Lanoy Jonathan David	UT	O	SVP,Chie	S	-83	16.51	-5	-9	50	D
8/15/25 12:12	8/13/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	Brower Nathan G	UT	O	EVP,GC	S	-165	16.54	-10	-17	48	D
8/15/25 10:55	8/13/25	LH	Labcorp Holdings Inc.		Health	Health	Medical Laboratories	Van Der Vaart Sandra D	NC	O	EVP,GC	S.d	-1,059	271.43	-4	-63	2	D
8/15/25 08:24	8/13/25	BCRX	Biocryst Pharmaceuticals Inc	DE	Health	BioPrd	Biological Products, (No Diag	Heggie Theresa	NC	D		S.d	-596	8.51	-70	-52	65	D
8/15/25 08:00	8/13/25	RDNT	Radnet, Inc.	DE	Health	Health	Medical Laboratories	Katz David Jeffrey	CA	O	EVP,GC	S	-1,161	68.31	-17	-16	87	D
8/14/25 20:33	8/12/25	DNLI	Denali Therapeutics Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Schuth Alexander O.	CA	O	COFO,Sec	S	-40	13.58	-3	0	766	D
8/14/25 20:33	8/12/25	DNLI	Denali Therapeutics Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Ho Carole	CA	O	Chief Me	S.m	-52	13.81	-4	-1	425	D
8/14/25 19:43	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moore John R	CO	O	GC	S.d	-28	13.39	-2	-17	10	D
8/14/25 19:43	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Derakhshan Behrad	CO	O	Chief Bu	S.d	-33	13.39	-2	-10	24	D
8/14/25 19:43	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Carruthers R Michael	CO	O	CFO	S.d	-19	13.39	-1	-2	86	D
8/14/25 19:42	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Russell Alan J	CO	DO	Chief Sc	S.d	-26	13.39	-2	-8	23	D
8/14/25 19:42	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Koch Kevin	CO	DO	P,CEO	S.d	-107	13.39	-8	-2	369	D
8/14/25 19:41	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Donovan Joanne M.	CO	O	CMO	S.d	-38	13.39	-3	-10	25	D
8/14/25 18:48	8/12/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	S.dm	-2,705	96.29	-28	-19	117	D
8/14/25 18:47	8/12/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	German Christopher Paul	MA	O	Corporat	S.d	-143	95.00	-2	-62	1	D
8/14/25 18:02	8/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	S.d	-147	12.93	-11	-11	93	D
8/14/25 18:01	8/12/25	IDXX	Idexx Laboratories Inc /De	DE	Health	Diagn	In Vitro & In Vivo Diagnostic	Erickson Michael G	ME	O	EVP	S	-264	649.96	0	-3	11	D
8/14/25 17:53	8/12/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Rowland Thomas Andrew	MN	O	SVP,HEAD	S	-426	85.71	-5	-11	41	D
8/14/25 17:48	8/12/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Lalwani Nikhil	MN	DO	P,CEO	S	-4,895	85.93	-57	-12	411	D
8/14/25 17:46	8/12/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Gutwerg Ori	MN	O	SVP,GENE	S	-508	86.53	-6	-7	84	D
8/14/25 17:43	8/13/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	S	-36	88.87	0	-1	76	D
8/14/25 17:40	8/12/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Carey Stephen P.	MN	O	SVP,CFO	S.d	-4,304	86.07	-50	-22	181	D
8/14/25 17:38	8/12/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Haughey Thomas	MN	D		S	-1,662	85.93	-19	-35	37	D
8/14/25 17:25	8/13/25	BDSX	Biodesix Inc	DE	Health	Health	Medical Laboratories	Cowie Robin Harper	CO	O	CFO,Sec'	S.d	0	0.4163	-1	0	251	D
8/14/25 17:25	8/13/25	BDSX	Biodesix Inc	DE	Health	Health	Medical Laboratories	Hutton Scott	CO	DO	P,CEO	S.d	-2	0.4163	-4	-1	729	D
8/14/25 17:24	8/13/25	BDSX	Biodesix Inc	DE	Health	Health	Medical Laboratories	O'Kane Kieran	CO	O	Chief Co	S.d	0	0.4163	0	0	140	D
8/14/25 17:24	8/13/25	BDSX	Biodesix Inc	DE	Health	Health	Medical Laboratories	Pestano Gary Anthony	CO	O	Chief De	S.d	0	0.4163	0	0	158	D
8/14/25 17:24	8/13/25	BDSX	Biodesix Inc	DE	Health	Health	Medical Laboratories	Vazquez Chris	CO	O	Chief Ac	S.d	0	0.4163	0	-1	18	D
8/14/25 17:22	8/12/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Du Ying	MA	DO	Chairper	S.dm	-3,358	34.84	-96	-15	537	D
8/14/25 17:00	8/12/25	ABBV	Abbvie Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saleki-Gerhardt Azita	IL	O	EVP,CHIE	S.d	-8,407	198.42	-42	-19	184	D
8/14/25 16:59	8/12/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Malley Thomas	X0	D		S.dm	-5,860	32.96	-178	-68	85	D
8/14/25 16:56	8/13/25	VMD	Viemed Healthcare, Inc.	A1	Health	Health	Misc Health & Allied Services	Cambre Jerome	LA	O	VP of Sa	S	-36	7.32	-5	-5	84	D
8/14/25 16:30	8/13/25	EXAS	Exact Sciences Corp	DE	Health	Health	Medical Laboratories	Doyle James Edward	WI	D		S	-62	42.02	-1	-2	60	D
8/14/25 16:30	8/12/25	LMAT	Lemaitre Vascular Inc		Health	MdEq	Surgical & Medical Instrument	Jasinski Lawrence J	MA	D		S	-91	92.78	-1	-17	5	D
8/14/25 16:27	8/12/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	S.d	-29	5.25	-6	-100	0	D
8/14/25 16:21	8/12/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Sharoky Melvin Md	NJ	D		S	-1,216	121.58	-10	-3	334	M
8/14/25 16:20	8/12/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazzariello Gina	MA	O	GC	S.m	-246	8.20	-30	-16	157	D
8/14/25 16:15	8/13/25	DSGN	Design Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	William Arsani	CA	D		S	-2,954	5.25	-563	-13	3,655	I
8/14/25 09:58	8/12/25	AORT	Artivion, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Holloway Jean F	GA	O	SVP,GC	S.d	-1,005	43.01	-23	-12	172	D
8/14/25 09:56	8/12/25	AORT	Artivion, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Davis John E	GA	O	Chief Co	S.d	-472	43.67	-11	-5	209	D
8/13/25 21:10	8/11/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seely Lynn	CA	DO	P,CEO	S.m	-8	10.43	-1	-2	35	D
8/13/25 21:09	8/11/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hill Stephen J.	CA	O	COO	S.m	-2	10.43	0	-2	9	D
8/13/25 21:08	8/11/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lee Gary K.	CA	O	Chief Sc	S.m	-3	10.43	0	-3	9	D
8/13/25 21:06	8/11/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Newton Charles W.	CA	O	CFO	S.m	-3	10.43	0	-1	19	D
8/13/25 21:03	8/11/25	RXRX	Recursion Pharmaceuticals, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Gibson Christopher	UT	DO	CEO	S.d	-3,264	5.28	-618	-38	995	M
8/13/25 20:22	8/11/25	WRBY	Warby Parker Inc.	DE	Health	OthMd	Ophthalmic Goods	Briggs Teresa	NY	D		S	-141	23.56	-6	-9	61	D
8/13/25 20:19	8/13/25	WRBY	Warby Parker Inc.	DE	Health	OthMd	Ophthalmic Goods	Blumenthal Neil Harris	NY	DO	Co-CEO	S.d	-1,256	25.11	-50	-10	428	D
8/13/25 20:00	8/13/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Henry Christian O	MA	D		S.d	-85	8.81	-10	-25	30	D
8/13/25 19:44	8/12/25	PEN	Penumbra Inc	DE	Health	MdEq	Surgical & Medical Instrument	Wilder Thomas	CA	D		S	-89	240.16	0	-7	5	D
8/13/25 19:40	8/11/25	PEN	Penumbra Inc	DE	Health	MdEq	Surgical & Medical Instrument	Roberts Johanna	CA	O	EVP,Gen.	S	-143	238.94	-1	-1	65	D
8/13/25 18:43	8/11/25	BLFS	Biolife Solutions Inc	DE	Health	ElcMd	Electromedical & Electrothera	Casdin Partners Master Fund, L.P.	NY	T		S	-11,300	22.60	-500	-6	7,207	I
8/13/25 18:37	8/12/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	S.d	-597	47.79	-13	-5	257	D
8/13/25 18:37	8/11/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	S	-1,458	48.59	-30	-6	491	D
8/13/25 18:32	8/11/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	S.d	-359	90.08	-4	-32	9	D
8/13/25 18:22	8/11/25	HALO	Halozyme Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Torley Helen	CA	DO	P,CEO	S.dm	-3,817	63.62	-60	-8	734	D
8/13/25 18:18	8/13/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedman Paul A	PA	D		S.d	-47,825	370.24	-129	-13	843	D
8/13/25 18:12	8/11/25	PGNY	Progyny, Inc.	DE	Health	Health	Misc Health & Allied Services	Gordon Kevin K	NY	D		S	-55	22.04	-3	-11	21	I
8/13/25 18:03	8/11/25	ALDX	Aldeyra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Machatha Stephen	MA	O	Chief De	S	-114	5.15	-22	-9	222	D
8/13/25 17:45	8/11/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedman Paul A	PA	D		S.dm	-16,631	355.31	-47	-5	843	D
8/13/25 17:33	8/11/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taub Rebecca	PA	D		S.dm	-16,509	355.32	-46	-4	1,117	D
8/13/25 17:17	8/11/25	IDXX	Idexx Laboratories Inc /De	DE	Health	Diagn	In Vitro & In Vivo Diagnostic	Hunt Nimrata	ME	O	EVP	S.d	-788	656.53	-1	-6	18	D
8/13/25 17:08	8/11/25	LMAT	Lemaitre Vascular Inc		Health	MdEq	Surgical & Medical Instrument	Roberts David B	MA	DO	P,Dir	S.d	-999	92.39	-11	-38	18	D
8/13/25 16:59	8/12/25	VMD	Viemed Healthcare, Inc.	A1	Health	Health	Misc Health & Allied Services	Moore Michael	LA	O	P	S	-367	7.33	-50	-3	1,849	D
8/13/25 16:47	8/12/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Halkuff Dawn	IL	D		S	-309	7.28	-43	-26	120	D
8/13/25 16:40	8/12/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Shah Nikita	NJ	O	EVP	S	-452	9.04	-50	-13	339	D
8/13/25 16:39	8/12/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Daly Jason B.	NJ	O	EVP,GC	S	-199	9.05	-22	-67	11	D
8/13/25 16:38	8/12/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Boyer Andrew S	NJ	O	EVP	S	-303	9.05	-33	-12	257	D
8/13/25 16:32	8/11/25	TARS	Tarsus Pharmaceuticals, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Azamian Bobak R.	CA	DO	P,CEO,Bo	S	-300	50.00	-6	-1	872	I
8/13/25 16:22	8/12/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	Degolyer Donald W	MD	D		S	-68	8.65	-8	-5	138	D
8/13/25 16:16	8/11/25	SGRY	Surgery Partners, Inc.	DE	Health	Health	General Medical & Surgical Ho	Maryland Patricia Anne	TN	D		S	-455	22.74	-20	-81	5	D
8/13/25 16:05	8/11/25	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Gaskins Tammi L	MA	O	Chief Co	S	-1	0.8400	-1	-1	241	D
8/13/25 16:05	8/11/25	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	John Minardo	MA	O	GC	S	-7	0.8400	-8	-2	400	D
8/13/25 16:05	8/11/25	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Martini Gregory S.	MA	O	CFO	S	-1	0.8400	-1	-1	183	D
8/13/25 16:05	8/11/25	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Silver Ronald	MA	O	Principa	S	-2	0.8400	-3	-1	277	D
8/13/25 12:29	8/11/25	LH	Labcorp Holdings Inc.		Health	Health	Medical Laboratories	Schechter Adam H	NC	DO	P,CEO	S	-1,505	266.78	-6	-6	93	D
8/13/25 09:58	8/11/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Schoenberg Mark	NJ	O	Chief Me	S	-177	17.69	-10	-6	148	D
8/13/25 08:55	8/8/25	LMAT	Lemaitre Vascular Inc		Health	MdEq	Surgical & Medical Instrument	Ross Bridget A	MA	D		S.d	-235	94.00	-3	-46	3	D
8/13/25 08:54	8/8/25	LMAT	Lemaitre Vascular Inc		Health	MdEq	Surgical & Medical Instrument	Roush John A	MA	D		S.dm	-695	92.67	-8	-72	3	D
8/12/25 21:05	8/8/25	NTRA	Natera, Inc.	DE	Health	Health	Medical Laboratories	Sheena Jonathan	TX	DH	CO-FOUND	S.m	-958	157.84	-6	-2	311	M
8/12/25 21:00	8/11/25	USPH	U S Physical Therapy Inc /Nv	NV	Health	Health	Health Services	Reeve Graham D.	TX	O	COO	S	-155	86.57	-2	-7	24	D
8/12/25 20:32	8/12/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Henderson Jane	CA	D		S.d	-142	47.46	-3	-24	9	D
8/12/25 20:00	8/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bjerkholt Eric	CA	O	CFO	S.d	0	0.00	-8	-20	31	D
8/12/25 19:57	8/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peetz Christopher	CA	DO	CEO	S.d	-2,480	62.00	-40	-10	347	D
8/12/25 19:22	8/11/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		S.d	-159	72.30	-2	-100	0	D
8/12/25 19:19	8/8/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	S.d	-2,512	71.77	-35	-86	5	D
8/12/25 19:06	8/8/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Homcy Charles J	CA	D		S.m	-13,912	46.37	-300	-25	917	D
8/12/25 18:03	8/8/25	TCMD	Tactile Systems Technology Inc	DE	Health	MdEq	Surgical & Medical Instrument	Dodd Sheri Louise	MN	DO	CEO	S	-96	12.36	-8	-4	173	D
8/12/25 17:28	8/11/25	STE	Steris Plc	L2	Health	Orthop	Orthopedic, Prosthetic & Surg	Sohi Mohsen	L2	D		S.d	-994	241.96	-4	-16	22	D
8/12/25 17:25	8/11/25	STE	Steris Plc	L2	Health	Orthop	Orthopedic, Prosthetic & Surg	Feldmann Cynthia L	L2	D		S.d	-844	241.56	-3	-27	9	D
8/12/25 17:20	8/11/25	STE	Steris Plc	L2	Health	Orthop	Orthopedic, Prosthetic & Surg	Burton Karen L	L2	O	VP,CAO	S.d	-1,910	241.73	-8	-57	6	D
8/12/25 17:18	8/8/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Freund John Gordon	MA	D		S	-401	34.36	-12	-10	102	I
8/12/25 17:04	8/8/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	S	-54	14.03	-4	-3	109	D
8/12/25 17:00	8/8/25	IDXX	Idexx Laboratories Inc /De	DE	Health	Diagn	In Vitro & In Vivo Diagnostic	Underberg Sharon E.	ME	O	EVP,GC,C	S.d	-3,551	651.60	-5	-46	6	D
8/12/25 16:45	8/8/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Amado Rafael	MA	O	See Rema	S	-105	35.00	-3	-7	42	D
8/12/25 16:45	8/8/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	S	-139	34.01	-4	-20	17	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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