10/8/25 21:08 | 10/6/25 | AXSM | Axsome Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Tabuteau Herriot | NY | DOT | CEO | S.dm | -5,418 | 119.38 | 0 | -45 | -1 | 7,352 | D | | | | | | | | | | | | | | |
10/8/25 21:00 | 10/6/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Venker Eric | X0 | O | P,Immuno | S.dm | -10,782 | 16.21 | 0 | -665 | -31 | 1,505 | D | | | | | | | | | | | | | | |
10/8/25 20:55 | 10/6/25 | SPRB | Spruce Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Parkman Healthcare Partners LLC | CT | T | | S | -5 | 19.14 | 0 | 0 | -20 | 1 | I | | | | | | | | | | | | | | |
10/8/25 20:12 | 10/6/25 | SGHT | Sight Sciences, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Taylor Brenton | CA | O | EVP,Oper | S | -2 | 3.37 | 0 | -1 | 0 | 185 | D | | | | | | | | | | | | | | |
10/8/25 19:48 | 10/1/25 | RMTI | Rockwell Medical, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hunter Heather | MI | O | SVP,COO | S | -3 | 1.19 | 0 | -3 | -2 | 135 | D | | | | | | | | | | | | | | |
10/8/25 19:08 | 10/6/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Jarrett Jennifer | CA | O | COO | S.dm | -750 | 14.92 | 0 | -50 | -19 | 214 | D | | | | | | | | | | | | | | |
10/8/25 18:37 | 10/6/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Swayze Eric | CA | O | EVP Rese | S | -473 | 69.02 | 0 | -7 | -18 | 31 | D | | | | | | | | | | | | | | |
10/8/25 18:37 | 10/6/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | O'Neil Patrick R. | CA | O | EVP CLO, | S.d | -937 | 69.74 | 0 | -13 | -20 | 54 | D | | | | | | | | | | | | | | |
10/8/25 18:36 | 10/6/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Monia Brett P | CA | DO | CEO | S | -30 | 69.26 | 0 | 0 | 0 | 180 | D | | | | | | | | | | | | | | |
10/8/25 18:36 | 10/6/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Baroldi Joseph | CA | O | EVP,Chie | S | -113 | 69.37 | 0 | -2 | -5 | 33 | D | | | | | | | | | | | | | | |
10/8/25 17:37 | 10/6/25 | ORIC | Oric Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Piscitelli Dominic | CA | O | CFO | S.d | -160 | 14.52 | 0 | -11 | -19 | 48 | D | | | | | | | | | | | | | | |
10/8/25 17:35 | 10/6/25 | ORIC | Oric Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Chacko Jacob | CA | DO | P,CEO | S | -462 | 12.32 | 0 | -37 | -7 | 531 | D | | | | | | | | | | | | | | |
10/8/25 17:33 | 10/6/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hyep Ivan | MA | O | CFO | S.dm | -553 | 18.21 | 0 | -30 | -17 | 145 | D | | | | | | | | | | | | | | |
10/8/25 17:33 | 10/6/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cohlhepp Ryan | MA | DO | P,COO | S.dm | -912 | 18.06 | 0 | -51 | -20 | 203 | D | | | | | | | | | | | | | | |
10/8/25 17:20 | 10/6/25 | VOR | Vor Biopharma Inc. | | Health | BioPrd | Biological Products, (No Diag | Reprogrammed Interchange LLC | CA | T | | S.m | -3,553 | 36.12 | 0 | -98 | -6 | 1,499 | D | | | | | | | | | | | | | | |
10/8/25 16:35 | 10/7/25 | SERA | Sera Prognostics, Inc. | DE | Health | Health | Medical Laboratories | Harrison Robert Gardner | UT | O | CIO | S | -6 | 3.18 | 0 | -2 | -2 | 98 | D | | | | | | | | | | | | | | |
10/8/25 16:34 | 10/6/25 | STE | Steris Plc | L2 | Health | Orthop | Orthopedic, Prosthetic & Surg | Carestio Daniel A | L2 | DO | P,CEO | S | -38 | 241.82 | 0 | 0 | 0 | 51 | D | | | | | | | | | | | | | | |
10/8/25 16:31 | 10/7/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | S.dm | -3,611 | 451.35 | 0 | -8 | -1 | 644 | D | | | | | | | | | | | | | | |
10/8/25 16:16 | 10/7/25 | CARM | Carisma Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Klichinsky Michael | PA | O | Chief Sc | S.d | -14 | 0.2542 | 0 | -57 | -100 | 0 | D | | | | | | | | | | | | | | |
10/8/25 16:14 | 10/6/25 | GRAL | Grail, Inc. | | Health | Health | Medical Laboratories | Ofman Joshua J. | CA | O | P | S | -5,087 | 62.50 | 0 | -81 | -17 | 397 | D | | | | | | | | | | | | | | |
10/8/25 16:10 | 10/6/25 | AIMD | Ainos, Inc. | TX | Health | Drug | Pharmaceutical Preparations | Taiwan Carbon Nano Technology Corp | F5 | T | | S | -25 | 3.59 | 0 | -7 | -1 | 1,037 | D | | | | | | | | | | | | | | |
10/8/25 16:05 | 10/6/25 | TWST | Twist Bioscience Corp | DE | Health | BioPrd | Biological Products, (No Diag | Laponis Adam | CA | O | CFO | S | -189 | 32.19 | 0 | -6 | -6 | 97 | D | | | | | | | | | | | | | | |
10/8/25 16:05 | 10/6/25 | TWST | Twist Bioscience Corp | DE | Health | BioPrd | Biological Products, (No Diag | Leproust Emily M. | CA | DO | CEO | S.d | -1,009 | 32.19 | 0 | -31 | -5 | 601 | D | | | | | | | | | | | | | | |
10/8/25 16:05 | 10/6/25 | TWST | Twist Bioscience Corp | DE | Health | BioPrd | Biological Products, (No Diag | Werner Robert F. | CA | O | Chief Ac | S | -66 | 32.19 | 0 | -2 | -4 | 46 | D | | | | | | | | | | | | | | |
10/8/25 16:05 | 10/6/25 | TWST | Twist Bioscience Corp | DE | Health | BioPrd | Biological Products, (No Diag | Green Paula | CA | O | SVP of H | S | -313 | 32.19 | 0 | -10 | -8 | 115 | D | | | | | | | | | | | | | | |
10/8/25 16:05 | 10/6/25 | TWST | Twist Bioscience Corp | DE | Health | BioPrd | Biological Products, (No Diag | Finn Patrick John | CA | O | P,COO | S | -764 | 32.19 | 0 | -24 | -10 | 209 | D | | | | | | | | | | | | | | |
10/8/25 16:05 | 10/6/25 | TWST | Twist Bioscience Corp | DE | Health | BioPrd | Biological Products, (No Diag | Cho Dennis | CA | O | See Rema | S | -125 | 32.19 | 0 | -4 | -4 | 99 | D | | | | | | | | | | | | | | |
10/8/25 16:00 | 10/7/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S | -22,722 | 848.01 | 0 | -27 | 0 | 94,649 | D | | | | | | | | | | | | | | |
10/8/25 06:50 | 10/6/25 | ALZN | Alzamend Neuro, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ault Milton C III | NV | D | | S.dm | -344 | 2.47 | 0 | -139 | -63 | 82 | I | | | | | | | | | | | | | | |
10/7/25 21:49 | 10/7/25 | MGTX | Meiragtx Holdings Plc | | Health | BioPrd | Biological Products, (No Diag | Forbes Alexandria | NY | DO | P,CEO | S | -399 | 8.39 | 0 | -48 | -3 | 1,314 | D | | | | | | | | | | | | | | |
10/7/25 20:22 | 10/6/25 | CVKD | Cadrenal Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Szot Matthew K | FL | O | CFO | S | -1 | 13.99 | 0 | 0 | -1 | 17 | D | | | | | | | | | | | | | | |
10/7/25 19:18 | 10/2/25 | PLSE | Pulse Biosciences, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Danahy Kevin Patrick | CA | O | Chief Co | S.d | -85 | 18.53 | 0 | -5 | -10 | 43 | D | | | | | | | | | | | | | | |
10/7/25 18:29 | 10/3/25 | CBLL | Ceribell, Inc. | DE | Health | ElcMd | Electromedical & Electrothera | Woo Raymond | CA | O | CTO | S.d | -139 | 12.54 | 0 | -11 | -6 | 168 | D | | | | | | | | | | | | | | |
10/7/25 18:14 | 10/3/25 | BYSI | Beyondspring Inc. | | Health | Drug | Pharmaceutical Preparations | Decheng Capital China Life Sciences Usd Fund Iii, L.P. | CA | T | | S.m | -36 | 1.78 | 0 | -20 | 0 | 4,327 | I | | | | | | | | | | | | | | |
10/7/25 17:18 | 10/6/25 | AXGN | Axogen, Inc. | MN | Health | ElcMd | Electromedical & Electrothera | Burke William P. Mr. | FL | D | | S | -13 | 18.00 | 0 | -1 | -32 | 2 | D | | | | | | | | | | | | | | |
10/7/25 17:08 | 10/7/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Malik Fady Ibraham | CA | O | EVP Rese | S.d | -121 | 60.56 | 0 | -2 | -1 | 141 | D | | | | | | | | | | | | | | |
10/7/25 17:00 | 10/3/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Booth Bruce | MA | D | | S.m | -1,486 | 29.99 | 0 | -50 | -1 | 3,566 | I | | | | | | | | | | | | | | |
10/7/25 17:00 | 10/6/25 | IRMD | Iradimed Corp | DE | Health | MdEq | Surgical & Medical Instrument | Susi Roger E. | FL | DOT | CEO,P,CB | S | -359 | 71.72 | 0 | -5 | 0 | 4,568 | I | | | | | | | | | | | | | | |
10/7/25 16:47 | 10/3/25 | HIMS | Hims & Hers Health, Inc. | DE | Health | Health | Offices & Clinics of Doctors | Okupe Oluyemi | CA | O | CFO | S.d | -669 | 57.72 | 0 | -12 | -13 | 78 | D | | | | | | | | | | | | | | |
10/7/25 16:32 | 10/6/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Benkowitz Michael | MD | O | P,COO | S.d | -10,130 | 450.24 | 0 | -23 | -89 | 3 | I | | | | | | | | | | | | | | |
10/7/25 16:30 | 10/3/25 | VYGR | Voyager Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Jorgensen Nathan D. | MA | O | CFO | S | -37 | 4.78 | 0 | -8 | -6 | 124 | D | | | | | | | | | | | | | | |
10/7/25 16:30 | 10/3/25 | VIR | Vir Biotechnology, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Svf Endurance (Cayman) Ltd | E9 | T | | S.m | -2,922 | 5.57 | 0 | -524 | -3 | 16,160 | I | | | | | | | | | | | | | | |
10/7/25 16:27 | 10/6/25 | VCYT | Veracyte, Inc. | DE | Health | Health | Medical Laboratories | Febbo Phillip G. | CA | O | Chief Sc | S | -301 | 36.02 | 0 | -8 | -8 | 92 | D | | | | | | | | | | | | | | |
10/7/25 16:26 | 10/3/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kaye Edward M. Md | MA | D | | S | -1,065 | 25.09 | 0 | -42 | -46 | 49 | D | | | | | | | | | | | | | | |
10/7/25 16:26 | 10/3/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Allan Jonathan | MA | O | GC,Corp | S.d | -251 | 25.07 | 0 | -10 | -46 | 12 | D | | | | | | | | | | | | | | |
10/7/25 16:15 | 10/3/25 | BBNX | Beta Bionics, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Feider Stephen | CA | O | CFO | S.d | -108 | 21.69 | 0 | -5 | -10 | 44 | D | | | | | | | | | | | | | | |
10/7/25 16:11 | 10/3/25 | RNA | Avidity Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mosbrooker Eric | CA | O | Chief Co | S.d | -298 | 45.38 | 0 | -7 | -11 | 55 | D | | | | | | | | | | | | | | |
10/7/25 16:00 | 10/6/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S | -137,042 | 850.22 | 0 | -161 | 0 | 94,676 | D | | | | | | | | | | | | | | |
10/6/25 20:00 | 10/2/25 | NXGL | Nexgel, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Henry Scott Robert | PA | D | | S.m | -20 | 2.55 | 0 | -8 | -7 | 113 | D | | | | | | | | | | | | | | |
10/6/25 20:00 | 10/2/25 | NXGL | Nexgel, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Levy Adam R. | PA | DO | CEO | S.m | -10 | 2.53 | 0 | -4 | -1 | 372 | D | | | | | | | | | | | | | | |
10/6/25 19:21 | 10/3/25 | ACLX | Arcellx, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Gilson Michelle | CA | O | CFO | S.m | -512 | 86.04 | 0 | -6 | -30 | 14 | D | | | | | | | | | | | | | | |
10/6/25 18:22 | 10/6/25 | FENC | Fennec Pharmaceuticals Inc. | A1 | Health | BioPrd | Biological Products, (No Diag | Raykov Rosty | NC | D | | S | -98 | 9.78 | 0 | -10 | -11 | 83 | D | | | | | | | | | | | | | | |
10/6/25 18:10 | 10/2/25 | SIBN | Si-Bone, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Pisetsky Michael A. | CA | O | SVP,Ops, | S | -45 | 14.25 | 0 | -3 | -1 | 255 | D | | | | | | | | | | | | | | |
10/6/25 18:10 | 10/2/25 | SIBN | Si-Bone, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Maheshwari Anshul | CA | O | CFO | S | -47 | 14.20 | 0 | -3 | -2 | 211 | D | | | | | | | | | | | | | | |
10/6/25 18:09 | 10/2/25 | SIBN | Si-Bone, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Recupero Anthony J | CA | O | P,Commer | S | -47 | 14.25 | 0 | -3 | -1 | 272 | D | | | | | | | | | | | | | | |
10/6/25 17:54 | 10/2/25 | AIMD | Ainos, Inc. | TX | Health | Drug | Pharmaceutical Preparations | Taiwan Carbon Nano Technology Corp | F5 | T | | S | -7 | 3.59 | 0 | -2 | 0 | 1,044 | D | | | | | | | | | | | | | | |
10/6/25 17:35 | 10/3/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | S.dm | -3,584 | 447.95 | 0 | -8 | -1 | 644 | D | | | | | | | | | | | | | | |
10/6/25 17:13 | 10/2/25 | OCUL | Ocular Therapeutix, Inc | DE | Health | Drug | Pharmaceutical Preparations | Kaiser Peter | MA | O | Chief De | S | -106 | 11.03 | 0 | -10 | -5 | 194 | D | | | | | | | | | | | | | | |
10/6/25 17:10 | 10/2/25 | OCUL | Ocular Therapeutix, Inc | DE | Health | Drug | Pharmaceutical Preparations | Heier Jeffrey S. | MA | O | Chief Sc | S | -116 | 11.04 | 0 | -11 | -4 | 249 | D | | | | | | | | | | | | | | |
10/6/25 16:54 | 10/2/25 | AXGN | Axogen, Inc. | MN | Health | ElcMd | Electromedical & Electrothera | Burke William P. Mr. | FL | D | | S.m | -584 | 18.14 | 0 | -32 | -93 | 2 | M | | | | | | | | | | | | | | |
10/6/25 16:45 | 10/2/25 | BCYC | Bicycle Therapeutics Plc | X0 | Health | Drug | Pharmaceutical Preparations | Lee Kevin | X0 | DO | CEO | S.m | -46 | 8.41 | 0 | -5 | -1 | 475 | D | | | | | | | | | | | | | | |
10/6/25 16:45 | 10/2/25 | BCYC | Bicycle Therapeutics Plc | X0 | Health | Drug | Pharmaceutical Preparations | Skynner Michael | X0 | O | CTO | S.m | -15 | 8.41 | 0 | -2 | -2 | 118 | D | | | | | | | | | | | | | | |
10/6/25 16:45 | 10/2/25 | BCYC | Bicycle Therapeutics Plc | X0 | Health | Drug | Pharmaceutical Preparations | Milnes Alistair | X0 | O | COO | S.m | -18 | 8.40 | 0 | -2 | -2 | 93 | D | | | | | | | | | | | | | | |
10/6/25 16:45 | 10/2/25 | BCYC | Bicycle Therapeutics Plc | X0 | Health | Drug | Pharmaceutical Preparations | Hannay Michael Charles Ferguson | X0 | O | CHIEF PR | S.m | -6 | 8.40 | 0 | -1 | -1 | 53 | D | | | | | | | | | | | | | | |
10/6/25 16:45 | 10/2/25 | BCYC | Bicycle Therapeutics Plc | X0 | Health | Drug | Pharmaceutical Preparations | Young Alethia | X0 | O | CFO | S | -4 | 8.51 | 0 | 0 | -1 | 45 | D | | | | | | | | | | | | | | |
10/6/25 16:45 | 10/2/25 | BCYC | Bicycle Therapeutics Plc | X0 | Health | Drug | Pharmaceutical Preparations | Thompson Travis Alvin | X0 | O | Chief Ac | S.m | -3 | 8.40 | 0 | 0 | -1 | 31 | D | | | | | | | | | | | | | | |
10/6/25 16:45 | 10/2/25 | BCYC | Bicycle Therapeutics Plc | X0 | Health | Drug | Pharmaceutical Preparations | Swanton Robert Charles | X0 | D | | S | -1 | 8.55 | 0 | 0 | -1 | 15 | D | | | | | | | | | | | | | | |
10/6/25 16:27 | 10/6/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Kaye Edward M. Md | CA | D | | S | -405 | 60.00 | 0 | -7 | -41 | 10 | D | | | | | | | | | | | | | | |
10/6/25 16:15 | 10/6/25 | SERA | Sera Prognostics, Inc. | DE | Health | Health | Medical Laboratories | Mirza Mansoor Raza | UT | D | | S | -1 | 3.16 | 0 | 0 | 0 | 58 | D | | | | | | | | | | | | | | |
10/6/25 16:11 | 10/2/25 | CSTL | Castle Biosciences Inc | DE | Health | Health | Medical Laboratories | Maetzold Derek J | TX | DO | P,Chief | S | -30 | 22.58 | 0 | -1 | 0 | 326 | D | | | | | | | | | | | | | | |
10/6/25 16:05 | 10/2/25 | TWST | Twist Bioscience Corp | DE | Health | BioPrd | Biological Products, (No Diag | Cho Dennis | CA | O | See Rema | S | -4 | 29.16 | 0 | 0 | 0 | 103 | D | | | | | | | | | | | | | | |
10/6/25 16:05 | 10/2/25 | TWST | Twist Bioscience Corp | DE | Health | BioPrd | Biological Products, (No Diag | Green Paula | CA | O | SVP of H | S | -4 | 29.16 | 0 | 0 | 0 | 124 | D | | | | | | | | | | | | | | |
10/6/25 16:05 | 10/2/25 | TWST | Twist Bioscience Corp | DE | Health | BioPrd | Biological Products, (No Diag | Leproust Emily M. | CA | DO | CEO | S.d | -14 | 29.16 | 0 | 0 | 0 | 633 | D | | | | | | | | | | | | | | |
10/6/25 16:05 | 10/2/25 | TWST | Twist Bioscience Corp | DE | Health | BioPrd | Biological Products, (No Diag | Finn Patrick John | CA | O | P,COO | S | -6 | 29.16 | 0 | 0 | 0 | 232 | D | | | | | | | | | | | | | | |
10/6/25 16:02 | 10/2/25 | INCY | Incyte Corp | DE | Health | Biolab | Commercial Physical & Biologi | Denton Sheila A. | DE | O | EVP,GC | S.dm | -352 | 85.85 | 0 | -4 | -13 | 27 | D | | | | | | | | | | | | | | |
10/6/25 16:00 | 10/3/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S | -161,220 | 837.93 | 0 | -192 | 0 | 94,837 | D | | | | | | | | | | | | | | |
10/6/25 15:15 | 10/2/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Edwards Larry Todd | CA | O | See Rema | S | -90 | 20.04 | 0 | -5 | -2 | 179 | D | | | | | | | | | | | | | | |
10/3/25 21:58 | 10/2/25 | ELTP | Elite Pharmaceuticals Inc /Nv/ | NJ | Health | Drug | Pharmaceutical Preparations | Plassche Douglas | NJ | O | EVP Oper | S | -499 | 0.6240 | 0 | -800 | -19 | 3,500 | D | | | | | | | | | | | | | | |
10/3/25 21:35 | 10/1/25 | ALZN | Alzamend Neuro, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ault Milton C III | NV | D | | S.dm | -297 | 2.41 | 0 | -123 | -85 | 21 | I | | | | | | | | | | | | | | |
10/3/25 21:27 | 10/1/25 | JAZZ | Jazz Pharmaceuticals Plc | L2 | Health | Drug | Pharmaceutical Preparations | Cozadd Bruce C | L2 | D | | S.m | -754 | 137.01 | 0 | -6 | -1 | 409 | D | | | | | | | | | | | | | | |
10/3/25 21:12 | 10/1/25 | VOR | Vor Biopharma Inc. | | Health | BioPrd | Biological Products, (No Diag | Reprogrammed Interchange LLC | CA | T | | S.m | -1,646 | 39.43 | 0 | -42 | -3 | 1,597 | D | | | | | | | | | | | | | | |
10/3/25 20:24 | 10/2/25 | CVKD | Cadrenal Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Pham Quang X | FL | DOT | CEO,CB | S | -7 | 14.13 | 0 | -1 | 0 | 402 | D | | | | | | | | | | | | | | |
10/3/25 20:00 | 10/1/25 | APGE | Apogee Therapeutics, Inc. | | Health | BioPrd | Biological Products, (No Diag | Dambkowski Carl | MA | O | Chief Me | S.d | -203 | 39.80 | 0 | -5 | -2 | 285 | D | | | | | | | | | | | | | | |
10/3/25 19:32 | 10/2/25 | PEN | Penumbra Inc | DE | Health | MdEq | Surgical & Medical Instrument | Grewal Harpreet | CA | D | | S | -46 | 248.61 | 0 | 0 | -2 | 9 | D | | | | | | | | | | | | | | |
10/3/25 19:31 | 10/1/25 | PEN | Penumbra Inc | DE | Health | MdEq | Surgical & Medical Instrument | Roberts Johanna | CA | O | EVP,Gen. | S | -150 | 249.70 | 0 | -1 | -1 | 64 | D | | | | | | | | | | | | | | |
10/3/25 19:30 | 10/1/25 | PEN | Penumbra Inc | DE | Health | MdEq | Surgical & Medical Instrument | Wilder Thomas | CA | D | | S | -47 | 253.93 | 0 | 0 | -4 | 5 | D | | | | | | | | | | | | | | |
10/3/25 19:01 | 10/2/25 | GRAL | Grail, Inc. | | Health | Health | Medical Laboratories | Ofman Joshua J. | CA | O | P | S | -620 | 64.00 | 0 | -10 | -2 | 478 | D | | | | | | | | | | | | | | |
10/3/25 19:00 | 10/1/25 | ATEC | Alphatec Holdings, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Miles Patrick | CA | DO | CEO | S | -1,396 | 13.96 | 0 | -100 | -2 | 5,725 | D | | | | | | | | | | | | | | |
10/3/25 18:15 | 10/1/25 | ARWR | Arrowhead Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hamilton James C | CA | O | Chief Me | S | -700 | 35.00 | 0 | -20 | -9 | 212 | D | | | | | | | | | | | | | | |
10/3/25 18:00 | 10/1/25 | HALO | Halozyme Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Torley Helen | CA | DO | P,CEO | S.dm | -4,312 | 71.86 | 0 | -60 | -8 | 734 | D | | | | | | | | | | | | | | |
10/3/25 17:53 | 10/2/25 | SGHT | Sight Sciences, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Bauerlein Alison | CA | O | CFO | S | -66 | 3.30 | 0 | -20 | -3 | 598 | D | | | | | | | | | | | | | | |
10/3/25 17:53 | 10/1/25 | SGHT | Sight Sciences, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Badawi Paul | CA | DOT | P,CEO | S | -82 | 3.34 | 0 | -24 | 0 | 5,963 | D | | | | | | | | | | | | | | |
10/3/25 17:53 | 10/3/25 | SGHT | Sight Sciences, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Badawi David | CA | DO | CTO | S | -20 | 3.27 | 0 | -6 | 0 | 1,865 | D | | | | | | | | | | | | | | |
10/3/25 17:52 | 10/3/25 | SGHT | Sight Sciences, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Hayden Jeremy B. | CA | O | GC | S | -32 | 3.27 | 0 | -10 | -4 | 257 | D | | | | | | | | | | | | | | |
10/3/25 17:50 | 10/1/25 | WRBY | Warby Parker Inc. | DE | Health | OthMd | Ophthalmic Goods | Gilboa David Abraham | NY | DO | Co-CEO | S.d | -3,413 | 27.30 | 0 | -125 | -79 | 33 | D | | | | | | | | | | | | | | |
10/3/25 17:25 | 10/1/25 | CARM | Carisma Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Klichinsky Michael | PA | O | Chief Sc | S.m | -124 | 0.2567 | 0 | -484 | -100 | 0 | D | | | | | | | | | | | | | | |
10/3/25 17:24 | 10/1/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Belanoff Joseph K | CA | DO | CEO | S | -3,403 | 85.08 | 0 | -40 | -1 | 2,781 | I | | | | | | | | | | | | | | |
10/3/25 17:17 | 10/1/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Lyon Joseph Douglas | CA | O | See Rema | S.d | -424 | 84.75 | 0 | -5 | -33 | 10 | D | | | | | | | | | | | | | | |
10/3/25 17:15 | 10/1/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Maduck Sean | CA | O | See Rema | S.d | -1,701 | 85.06 | 0 | -20 | -15 | 118 | D | | | | | | | | | | | | | | |
10/3/25 17:14 | 10/2/25 | ALNY | Alnylam Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Poulton Jeffrey V. | MA | O | EVP,CFO | S | -1,727 | 452.05 | 0 | -4 | -7 | 54 | D | | | | | | | | | | | | | | |
10/3/25 17:14 | 10/2/25 | ALNY | Alnylam Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Greenstreet Yvonne | MA | DO | CEO | S | -4,034 | 452.05 | 0 | -9 | -12 | 66 | D | | | | | | | | | | | | | | |
10/3/25 17:14 | 10/2/25 | ALNY | Alnylam Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Tanguler Tolga | MA | O | EVP,Chie | S | -635 | 452.05 | 0 | -1 | -5 | 27 | D | | | | | | | | | | | | | | |
10/3/25 17:13 | 10/1/25 | NTLA | Intellia Therapeutics, Inc. | DE | Health | Diagn | In Vitro & In Vivo Diagnostic | Schultes Birgit C | MA | O | EVP,Chie | S | -1 | 17.38 | 0 | 0 | 0 | 105 | D | | | | | | | | | | | | | | |
10/3/25 17:13 | 10/2/25 | ALNY | Alnylam Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Fitzgerald Kevin Joseph | MA | O | CSO,EVP, | S | -1,103 | 452.05 | 0 | -2 | -9 | 26 | D | | | | | | | | | | | | | | |
10/3/25 17:13 | 10/1/25 | NTLA | Intellia Therapeutics, Inc. | DE | Health | Diagn | In Vitro & In Vivo Diagnostic | Dube Michael P | MA | O | VP,Chief | S | -33 | 17.38 | 0 | -2 | -3 | 55 | D | | | | | | | | | | | | | | |
10/3/25 17:12 | 10/2/25 | ALNY | Alnylam Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Garg Pushkal | MA | O | EVP Chie | S.m | -2,692 | 451.76 | 0 | -6 | -22 | 21 | D | | | | | | | | | | | | | | |
10/3/25 17:02 | 10/1/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Watanabe Todd | CA | DO | See Rema | S.m | -885 | 19.66 | 0 | -45 | -4 | 1,080 | D | | | | | | | | | | | | | | |
10/3/25 17:01 | 10/1/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Welgus Howard G. | CA | D | | S.d | -189 | 18.92 | 0 | -10 | -9 | 100 | D | | | | | | | | | | | | | | |
10/3/25 17:01 | 10/1/25 | DNA | Ginkgo Bioworks Holdings, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Coen Steven P. | MA | O | See rema | S | -84 | 15.00 | 0 | -6 | -50 | 6 | D | | | | | | | | | | | | | | |
10/3/25 16:56 | 10/1/25 | KPTI | Karyopharm Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Abate Kristin | MA | O | Chief Ac | S | -2 | 6.30 | 0 | 0 | -3 | 10 | D | | | | | | | | | | | | | | |
10/3/25 16:45 | 10/1/25 | LGND | Ligand Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Kozarich John W | FL | D | | S | -84 | 179.44 | 0 | 0 | -1 | 45 | D | | | | | | | | | | | | | | |
10/3/25 16:41 | 10/1/25 | CRNX | Crinetics Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Pizzuti Dana | CA | O | Chief Me | S.d | -209 | 41.81 | 0 | -5 | -7 | 66 | D | | | | | | | | | | | | | | |
10/3/25 16:31 | 10/1/25 | BBNX | Beta Bionics, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Feider Stephen | CA | O | CFO | S.d | -312 | 20.76 | 0 | -15 | -25 | 44 | D | | | | | | | | | | | | | | |
10/3/25 16:30 | 10/1/25 | AKRO | Akero Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Young Jonathan | CA | O | COO | S.d | -597 | 47.76 | 0 | -13 | -5 | 257 | D | | | | | | | | | | | | | | |
10/3/25 16:28 | 10/1/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Balcom Alexandra | MA | O | CFO | S.d | -1,710 | 85.48 | 0 | -20 | -24 | 62 | D | | | | | | | | | | | | | | |
10/3/25 16:25 | 10/1/25 | NOTV | Inotiv, Inc. | IN | Health | Biolab | Commercial Physical & Biologi | Neff R Matthew | IN | D | | S | -3 | 1.43 | 0 | -2 | -1 | 145 | D | | | | | | | | | | | | | | |
10/3/25 16:25 | 10/1/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ticho Barry | MA | O | Chief Me | S | -126 | 23.64 | 0 | -5 | -29 | 13 | D | | | | | | | | | | | | | | |
10/3/25 16:25 | 10/1/25 | ENSG | Ensign Group, Inc | | Health | Health | Skilled Nursing Care Faciliti | Smith Barry M | CA | D | | S | -120 | 172.00 | 0 | -1 | -3 | 25 | D | | | | | | | | | | | | | | |
10/3/25 16:20 | 10/2/25 | ZLAB | Zai Lab Ltd | E9 | Health | Drug | Pharmaceutical Preparations | Chen Yajing | MA | O | CFO | S.d | -16 | 34.25 | 0 | 0 | -3 | 17 | D | | | | | | | | | | | | | | |
10/3/25 16:18 | 10/2/25 | SUPN | Supernus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Khattar Jack A. | MD | DO | P,CEO | S.d | -92 | 48.06 | 0 | -2 | 0 | 2,167 | D | | | | | | | | | | | | | | |
10/3/25 16:16 | 10/1/25 | VCYT | Veracyte, Inc. | DE | Health | Health | Medical Laboratories | Leite John | CA | O | Chief Co | S | -89 | 35.00 | 0 | -3 | -3 | 89 | D | | | | | | | | | | | | | | |
10/3/25 16:16 | 10/1/25 | VCYT | Veracyte, Inc. | DE | Health | Health | Medical Laboratories | Epstein Robert S | CA | D | | S.d | -753 | 35.08 | 0 | -21 | -26 | 62 | D | | | | | | | | | | | | | | |
10/3/25 16:16 | 10/1/25 | VCYT | Veracyte, Inc. | DE | Health | Health | Medical Laboratories | McGuire Annie | CA | O | SVP,GC | S | -76 | 35.00 | 0 | -2 | -2 | 89 | D | | | | | | | | | | | | | | |
10/3/25 16:15 | 10/1/25 | BEAM | Beam Therapeutics Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Cavanagh Bethany J | MA | O | SVP,Fina | S | -11 | 24.53 | 0 | 0 | -1 | 44 | D | | | | | | | | | | | | | | |
10/3/25 16:10 | 10/1/25 | BEAM | Beam Therapeutics Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Bellon Christine | MA | O | GC | S | -9 | 24.53 | 0 | 0 | 0 | 117 | D | | | | | | | | | | | | | | |
10/3/25 16:07 | 10/2/25 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Biller Jonathan | MA | O | EVP,GC | S | -281 | 404.21 | 0 | -1 | -4 | 16 | D | | | | | | | | | | | | | | |
10/3/25 16:05 | 10/2/25 | TDOC | Teladoc Health, Inc. | DE | Health | Health | Offices & Clinics of Doctors | Catapano Joseph Ronald | NY | O | Chief Ac | S.d | -23 | 7.89 | 0 | -3 | -36 | 5 | D | | | | | | | | | | | | | | |
10/3/25 16:05 | 10/1/25 | BEAM | Beam Therapeutics Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Evans John M. | MA | DO | CEO | S.dm | -1,228 | 24.57 | 0 | -50 | -4 | 1,090 | D | | | | | | | | | | | | | | |
10/3/25 16:00 | 10/2/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S | -92,503 | 821.55 | 0 | -113 | 0 | 95,029 | D | | | | | | | | | | | | | | |
10/3/25 12:56 | 10/1/25 | RMD | Resmed Inc | DE | Health | MdEq | Surgical & Medical Instrument | Sandercock Brett | CA | O | CFO | S.d | -823 | 274.36 | 0 | -3 | -3 | 87 | D | | | | | | | | | | | | | | |
10/2/25 20:51 | 9/30/25 | BYSI | Beyondspring Inc. | | Health | Drug | Pharmaceutical Preparations | Decheng Capital China Life Sciences Usd Fund Iii, L.P. | CA | T | | S.m | -14 | 1.80 | 0 | -8 | 0 | 4,347 | I | | | | | | | | | | | | | | |
10/2/25 19:36 | 10/1/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Wender Joseph H | CA | D | | S | -1,100 | 65.50 | 0 | -17 | -15 | 92 | I | | | | | | | | | | | | | | |
10/2/25 19:36 | 10/1/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Swayze Eric | CA | O | EVP Rese | S.dm | -1,794 | 66.16 | 0 | -27 | -42 | 37 | D | | | | | | | | | | | | | | |
10/2/25 19:35 | 10/2/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | O'Neil Patrick R. | CA | O | EVP CLO, | S.d | -4,377 | 67.69 | 0 | -65 | -53 | 57 | D | | | | | | | | | | | | | | |
10/2/25 19:35 | 10/2/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Baroldi Joseph | CA | O | EVP,Chie | S.d | -1,020 | 68.01 | 0 | -15 | -30 | 35 | D | | | | | | | | | | | | | | |
10/2/25 19:24 | 10/1/25 | TERN | Terns Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kuriakose Emil | CA | O | Chief Me | S | -7 | 7.85 | 0 | -1 | -2 | 52 | D | | | | | | | | | | | | | | |
10/2/25 19:18 | 9/30/25 | ORIC | Oric Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Chacko Jacob | CA | DO | P,CEO | S.m | -1,054 | 12.04 | 0 | -88 | -13 | 569 | D | | | | | | | | | | | | | | |
10/2/25 17:04 | 10/1/25 | AMPH | Amphastar Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Petersen Floyd F. | CA | D | | S | -14 | 27.20 | 0 | -1 | -1 | 76 | D | | | | | | | | | | | | | | |
10/2/25 17:00 | 10/1/25 | IRMD | Iradimed Corp | DE | Health | MdEq | Surgical & Medical Instrument | Susi Roger E. | FL | DOT | CEO,P,CB | S | -351 | 70.19 | 0 | -5 | 0 | 4,573 | I | | | | | | | | | | | | | | |
10/2/25 16:56 | 10/1/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S | -177,290 | 821.47 | 0 | -216 | 0 | 95,142 | D | | | | | | | | | | | | | | |
10/2/25 16:55 | 10/1/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S | -107,363 | 794.15 | 0 | -135 | 0 | 95,358 | D | | | | | | | | | | | | | | |
10/2/25 16:47 | 9/30/25 | KALA | Kala Bio, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Baker Bros. Advisors LP | NY | H | Former 1 | S.m | -1,057 | 1.45 | 0 | -730 | -63 | 425 | I | | | | | | | | | | | | | | |
10/2/25 16:40 | 9/30/25 | LENZ | Lenz Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Versant Venture Capital Vi, L.P. | CA | T | | S | -10,352 | 46.01 | 0 | -225 | -8 | 2,657 | M | | | | | | | | | | | | | | |
10/2/25 16:32 | 10/1/25 | RMD | Resmed Inc | DE | Health | MdEq | Surgical & Medical Instrument | Rider Michael J | CA | O | Global G | S | -27 | 274.36 | 0 | 0 | -1 | 11 | D | | | | | | | | | | | | | | |
10/2/25 16:30 | 10/1/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | S.dm | -3,441 | 430.17 | 0 | -8 | -1 | 644 | D | | | | | | | | | | | | | | |
10/2/25 16:30 | 10/2/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Mahon Paul A | MD | O | EVP,GC | S.d | -4,803 | 436.60 | 0 | -11 | -23 | 37 | D | | | | | | | | | | | | | | |
10/2/25 16:15 | 9/30/25 | AMLX | Amylyx Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Klee Justin B. | MA | DO | Co-CEO | S | -431 | 14.38 | 0 | -30 | -1 | 3,325 | D | | | | | | | | | | | | | | |
10/2/25 16:15 | 9/30/25 | AMLX | Amylyx Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mazzariello Gina | MA | O | GC | S | -129 | 14.58 | 0 | -9 | -6 | 148 | D | | | | | | | | | | | | | | |
10/2/25 16:15 | 9/30/25 | AMLX | Amylyx Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Frates James M | MA | O | CFO | S | -155 | 14.65 | 0 | -11 | -3 | 307 | D | | | | | | | | | | | | | | |
10/2/25 16:15 | 9/30/25 | AMLX | Amylyx Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cohen Joshua B | MA | DO | Co-CEO | S | -429 | 14.35 | 0 | -30 | -1 | 3,325 | D | | | | | | | | | | | | | | |
10/2/25 16:15 | 9/30/25 | AMLX | Amylyx Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bedrosian Camille L | MA | O | Chief Me | S | -176 | 14.58 | 0 | -12 | -6 | 182 | D | | | | | | | | | | | | | | |
10/2/25 16:10 | 9/30/25 | AIMD | Ainos, Inc. | TX | Health | Drug | Pharmaceutical Preparations | Taiwan Carbon Nano Technology Corp | F5 | T | | S.m | -9 | 3.48 | 0 | -3 | 0 | 1,046 | D | | | | | | | | | | | | | | |
10/2/25 16:10 | 10/1/25 | HIMS | Hims & Hers Health, Inc. | DE | Health | Health | Offices & Clinics of Doctors | Chi Michael | CA | O | Chief Co | S.d | -14 | 56.00 | 0 | 0 | 0 | 291 | D | | | | | | | | | | | | | | |
10/2/25 16:10 | 9/30/25 | IMCR | Immunocore Holdings Plc | X0 | Health | BioPrd | Biological Products, (No Diag | Berman David M | X0 | O | HEAD OF | S.d | -2,179 | 35.23 | 0 | -62 | -100 | 0 | D | | | | | | | | | | | | | | |
10/2/25 16:03 | 9/30/25 | AGIO | Agios Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Scadden David | MA | D | | S.d | -8 | 40.00 | 0 | 0 | -1 | 18 | D | | | | | | | | | | | | | | |
10/2/25 16:02 | 10/1/25 | SUPN | Supernus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Khattar Jack A. | MD | DO | P,CEO | S.d | -1,931 | 48.07 | 0 | -40 | -2 | 2,166 | D | | | | | | | | | | | | | | |
10/2/25 16:02 | 9/30/25 | APLS | Apellis Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dunlop A. Sinclair | MA | D | | S | -702 | 22.58 | 0 | -31 | -14 | 189 | I | | | | | | | | | | | | | | |
10/2/25 11:53 | 10/1/25 | VIR | Vir Biotechnology, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Sato Vicki L | CA | D | | S | -128 | 5.84 | 0 | -22 | -2 | 1,232 | D | | | | | | | | | | | | | | |
10/1/25 21:35 | 10/1/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Moshkevich Solomon | TX | O | P,CLINIC | S | -480 | 159.99 | 0 | -3 | -2 | 118 | D | | | | | | | | | | | | | | |
10/1/25 21:35 | 9/30/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Rabinowitz Daniel | TX | O | SEC.,GC | S.d | -221 | 162.05 | 0 | -1 | -1 | 203 | D | | | | | | | | | | | | | | |
10/1/25 21:35 | 9/30/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Chapman Steven Leonard | TX | DO | CEO,P | S.dm | -3,729 | 160.80 | 0 | -23 | -13 | 154 | D | | | | | | | | | | | | | | |
10/1/25 21:35 | 9/30/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Brophy Michael Burkes | TX | O | CFO | S.d | -404 | 162.05 | 0 | -2 | -3 | 69 | D | | | | | | | | | | | | | | |
10/1/25 20:17 | 9/29/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Balcom Alexandra | MA | O | CFO | S.dm | -2,346 | 85.05 | 0 | -28 | -31 | 62 | D | | | | | | | | | | | | | | |
10/1/25 20:14 | 9/29/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Noci Darlene | MA | O | Chief De | S.d | -332 | 83.07 | 0 | -4 | -8 | 48 | D | | | | | | | | | | | | | | |
10/1/25 19:17 | 10/1/25 | XENE | Xenon Pharmaceuticals Inc. | A1 | Health | Drug | Pharmaceutical Preparations | Mortimer Ian | A1 | DO | P,CEO,IN | S.d | -1,004 | 40.16 | 0 | -25 | -35 | 46 | D | | | | | | | | | | | | | | |
10/1/25 18:29 | 10/1/25 | HALO | Halozyme Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Connaughton Bernadette | CA | D | | S | -150 | 75.24 | 0 | -2 | -4 | 45 | D | | | | | | | | | | | | | | |
10/1/25 18:04 | 9/29/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Booth Bruce | MA | D | | S.m | -2,367 | 30.08 | 0 | -79 | -2 | 3,615 | I | | | | | | | | | | | | | | |
10/1/25 17:47 | 9/29/25 | CVKD | Cadrenal Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Szot Matthew K | FL | O | CFO | S.m | -25 | 13.99 | 0 | -2 | -10 | 17 | D | | | | | | | | | | | | | | |
10/1/25 17:46 | 9/29/25 | CVKD | Cadrenal Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Pham Quang X | FL | DOT | CEO,CB | S.m | -18 | 14.01 | 0 | -1 | 0 | 403 | D | | | | | | | | | | | | | | |
10/1/25 17:22 | 9/29/25 | MLTX | Moonlake Immunotherapeutics | E9 | Health | Drug | Pharmaceutical Preparations | Chen Bihua | MA | H | Former 1 | S.m | -46,868 | 7.21 | 0 | -6,500 | -77 | 1,994 | I | | | | | | | | | | | | | | |
10/1/25 17:16 | 9/29/25 | PGEN | Precigen, Inc. | VA | Health | Drug | Pharmaceutical Preparations | Kindler Jeffrey B | MD | D | | S.m | -604 | 3.47 | 0 | -174 | -34 | 346 | D | | | | | | | | | | | | | | |
10/1/25 17:07 | 9/30/25 | CGON | Cg Oncology, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Post Leonard E | CA | D | | S.d | -200 | 40.09 | 0 | -5 | -100 | 0 | D | | | | | | | | | | | | | | |
10/1/25 17:02 | 9/29/25 | RGNX | Regenxbio Inc. | | Health | BioPrd | Biological Products, (No Diag | Simpson Curran | MD | DO | CEO | S | -76 | 10.03 | 0 | -8 | -3 | 237 | D | | | | | | | | | | | | | | |
10/1/25 16:57 | 9/29/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Meisner Lara | MA | O | GC | S.d | -499 | 14.75 | 0 | -34 | -100 | 0 | D | | | | | | | | | | | | | | |
10/1/25 16:55 | 9/29/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | O'Neil Patrick R. | CA | O | EVP CLO, | S.dm | -1,635 | 64.62 | 0 | -25 | -31 | 57 | D | | | | | | | | | | | | | | |
10/1/25 16:55 | 9/30/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Geary Richard S | CA | O | EVP,Chie | S.d | -3,778 | 65.24 | 0 | -58 | -42 | 80 | D | | | | | | | | | | | | | | |
10/1/25 16:55 | 9/30/25 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Diagn | In Vitro & In Vivo Diagnostic | Hougen Elizabeth L | CA | O | EVP,Fina | S.d | -3,250 | 65.26 | 0 | -50 | -31 | 111 | D | | | | | | | | | | | | | | |
10/1/25 16:46 | 9/29/25 | ELVN | Enliven Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hohl Benjamin | CO | O | CFO | S.d | -66 | 20.40 | 0 | -3 | -12 | 23 | D | | | | | | | | | | | | | | |
10/1/25 16:44 | 9/29/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | X0 | Health | Drug | Pharmaceutical Preparations | Tessari Eben | X0 | O | COO | S.d | -1,610 | 38.33 | 0 | -42 | -55 | 35 | D | | | | | | | | | | | | | | |
10/1/25 16:31 | 9/29/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Benkowitz Michael | MD | O | P,COO | S.d | -9,491 | 421.80 | 0 | -23 | -89 | 3 | I | | | | | | | | | | | | | | |
10/1/25 16:30 | 9/29/25 | ABEO | Abeona Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | O'Malley Brendan M. | OH | O | SVP,GC | S | -51 | 5.39 | 0 | -9 | -3 | 351 | D | | | | | | | | | | | | | | |
10/1/25 16:30 | 9/29/25 | ABEO | Abeona Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Seshadri Vishwas | OH | DO | CEO | S.m | -235 | 5.31 | 0 | -44 | -4 | 1,190 | D | | | | | | | | | | | | | | |
10/1/25 16:30 | 9/29/25 | ABEO | Abeona Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Vazzano Joseph Walter | OH | O | CFO | S | -49 | 5.39 | 0 | -9 | -2 | 454 | D | | | | | | | | | | | | | | |
10/1/25 16:26 | 10/1/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Blum Robert I | CA | DO | P,CEO | S | -275 | 55.05 | 0 | -5 | -1 | 372 | D | | | | | | | | | | | | | | |
10/1/25 16:24 | 10/1/25 | RMTI | Rockwell Medical, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Chole Timothy | MI | O | SVP,CCO | S | -3 | 1.19 | 0 | -3 | -2 | 125 | D | | | | | | | | | | | | | | |
10/1/25 16:23 | 10/1/25 | RMTI | Rockwell Medical, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Neri Jesse | MI | O | SVP,CFO | S | -1 | 1.19 | 0 | -1 | -1 | 126 | D | | | | | | | | | | | | | | |
10/1/25 16:22 | 10/1/25 | BSX | Boston Scientific Corp | DE | Health | MdEq | Surgical & Medical Instrument | Fitzgerald Joseph Michael | MA | O | EVP,Grou | S.d | -4,923 | 98.47 | 0 | -50 | -21 | 184 | D | | | | | | | | | | | | | | |
10/1/25 16:22 | 10/1/25 | RMTI | Rockwell Medical, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Strobeck Mark | MI | DO | P,CEO | S | -8 | 1.19 | 0 | -7 | -2 | 331 | D | | | | | | | | | | | | | | |
10/1/25 16:21 | 9/30/25 | WGS | Genedx Holdings Corp. | DE | Health | Health | Health Services | Stueland Katherine | CT | DO | CEO | S | -1,391 | 108.18 | 0 | -13 | -88 | 2 | D | | | | | | | | | | | | | | |
10/1/25 16:20 | 9/30/25 | SUPN | Supernus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Khattar Jack A. | MD | DO | P,CEO | S.d | -414 | 48.25 | 0 | -9 | 0 | 2,153 | D | | | | | | | | | | | | | | |
10/1/25 16:18 | 9/30/25 | WGS | Genedx Holdings Corp. | DE | Health | Health | Health Services | Feeley Kevin | CT | O | CFO | S.d | -716 | 108.38 | 0 | -7 | -66 | 3 | D | | | | | | | | | | | | | | |
10/1/25 16:10 | 9/30/25 | PAHC | Phibro Animal Health Corp | DE | Health | Drug | Pharmaceutical Preparations | Bendheim Jack | NJ | DOT | P,CEO | S | -834 | 40.38 | 0 | -21 | -26 | 58 | I | | | | | | | | | | | | | | |
10/1/25 16:00 | 9/30/25 | ANAB | Anaptysbio, Inc | DE | Health | Drug | Pharmaceutical Preparations | Loumeau Eric J | CA | O | GC | S.d | -239 | 29.00 | 0 | -8 | -48 | 9 | D | | | | | | | | | | | | | | |
10/1/25 16:00 | 9/30/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S | -86,793 | 763.39 | 0 | -114 | 0 | 95,493 | D | | | | | | | | | | | | | | |
10/1/25 08:00 | 9/29/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | S.dm | -3,394 | 424.24 | 0 | -8 | -1 | 644 | D | | | | | | | | | | | | | | |
9/30/25 20:16 | 9/30/25 | ACLX | Arcellx, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Heery Christopher | CA | O | CHIEF ME | S | -1,710 | 81.28 | 0 | -21 | -97 | 1 | D | | | | | | | | | | | | | | |
9/30/25 19:15 | 9/26/25 | ALZN | Alzamend Neuro, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ault Milton C III | NV | DT | | S.m | -184 | 2.31 | 0 | -80 | -64 | 45 | I | | | | | | | | | | | | | | |
9/30/25 18:59 | 9/29/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Azoy Alexander | CA | O | Chief Ac | S | -37 | 13.00 | 0 | -3 | -9 | 27 | D | | | | | | | | | | | | | | |
9/30/25 17:56 | 9/26/25 | AGIO | Agios Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Jones Cecilia | MA | O | CFO | S.d | -134 | 36.77 | 0 | -4 | -10 | 34 | D | | | | | | | | | | | | | | |
9/30/25 17:53 | 9/26/25 | ELVN | Enliven Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Lyssikatos Joseph P | CO | O | CHIEF SC | S | -81 | 20.25 | 0 | -4 | 0 | 928 | I | | | | | | | | | | | | | | |