Pharmaceutical Preparations Industry - Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
10/30/25 20:00	10/28/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meyer Andrew Hollman	CA	O	Chief Bu	2	M.d	614	18.41	33	68	82	D
10/30/25 20:00	10/28/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meyer Andrew Hollman	CA	O	Chief Bu	2	S.d	-614	18.41	-33		82	D
10/30/25 19:02	10/28/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watanabe Todd	CA	DO	See Rema	4	S.m	-2,229	20.89	-107		1,135	D
10/30/25 18:09	9/9/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	Bendheim Jack	NJ	DOT	P,CEO	6	S.dm	-3,855	40.56	-95		91	I
10/30/25 18:06	10/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Van Houte Hans	CA	O	CFO	2	M.d	40	2.74	15	50	44	D
10/30/25 18:06	10/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Van Houte Hans	CA	O	CFO	2	S.d	-40	2.74	-15		44	D
10/30/25 18:02	10/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ring Christine	CA	O	GC	2	M.d	47	3.29	14	39	51	D
10/30/25 18:02	10/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ring Christine	CA	O	GC	2	S.d	-47	3.29	-14		51	D
10/30/25 18:01	10/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hansen Gwenn	CA	O	Chief Sc	2	M.d	52	3.29	16	26	77	D
10/30/25 18:01	10/30/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hansen Gwenn	CA	O	Chief Sc	2	S.d	-52	3.29	-16		77	D
10/30/25 18:00	10/28/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yap Kim Choy	N8	T		3	S	-316	2.07	-153		385	D
10/30/25 16:47	10/28/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Ragosa Mark	X0	O	CFO	5	M.dm	1,061	23.12	46		31	D
10/30/25 16:47	10/28/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Ragosa Mark	X0	O	CFO	5	S.dm	-1,061	23.12	-46		31	D
10/30/25 16:45	10/28/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Dube Eric M	CA	DO	CEO	2	M.dm	5,494	22.89	240	134	419	D
10/30/25 16:45	10/28/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Dube Eric M	CA	DO	CEO	2	S.dm	-5,494	22.89	-240		419	D
10/30/25 16:45	10/28/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Heerma Peter	CA	O	Chief Co	1	S	-80	30.00	-3		125	D
10/30/25 16:44	10/28/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	10	M.d	5,650	66.94	84		9	D
10/30/25 16:44	10/28/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	10	S.d	-5,650	66.94	-84		9	D
10/30/25 16:37	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	14	M.d	40,332	261.89	154		37	D
10/30/25 16:37	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	14	S.d	-40,332	261.89	-154		37	D
10/30/25 16:31	10/28/25	MPLT	Maplight Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Novo Holdings A/S	G7	T		1	P.d	16,200	17.00	953	35	3,687	D
10/30/25 16:30	10/27/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	38	M.dm	80,468	271.85	296	85	644	D
10/30/25 16:30	10/27/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	38	S.dm	-80,468	271.85	-296		644	D
10/30/25 16:25	9/2/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	6	S	-1,574	52.48	-30		387	D
10/30/25 08:49	10/28/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jaen Juan C.	CA	O	P	1	S.m	-2,011	20.76	-97		1,459	I
10/29/25 20:43	10/23/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chesed Abraham	CA	H	Board Ob	1	P	66	4.60	14	1	1,447	I
10/29/25 19:22	10/27/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Evnin Luke	MA	D		1	S.m	-286	1.62	-177		4,133	I
10/29/25 19:21	10/27/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mpm Bioventures 2014, L.P.	MA	T		1	S.m	-446	1.62	-276		6,443	I
10/29/25 19:21	10/27/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gadicke Ansbert	MA	T		1	S.m	-446	1.62	-276		6,443	I
10/29/25 17:10	10/27/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCormick Frank	CA	D		3	S.d	-4,922	32.89	-150		963	I
10/29/25 17:04	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	16	M.dm	503	3.13	161		0	D
10/29/25 17:04	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	16	S.dm	-503	3.13	-161	-100	0	D
10/29/25 16:31	10/27/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shair Matthew	MA	D		1	S.m	-6,015	100.26	-60		1,586	M
10/29/25 16:30	10/27/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	5	S.dm	-841	19.68	-43		176	D
10/29/25 16:30	10/27/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Boyle Dana	NC	O	Chief Ac	3	S	-62	23.85	-3		187	D
10/29/25 16:24	10/27/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hattersley Gary	NY	O	Chief Sc	2	M.d	676	3.38	200		0	D
10/29/25 16:24	10/27/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hattersley Gary	NY	O	Chief Sc	2	S.d	-676	3.38	-200	-100	0	D
10/29/25 16:16	10/28/25	MLPT	Maplight Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Catalyst4, Inc.	CA	T		1	P.d	92,500	17.00	5,441	38	19,697	I
10/29/25 16:11	10/27/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mack David Henry	NJ	DO	P,CEO	1	M.d	302	1.37	221	24	1,127	D
10/29/25 16:02	10/27/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gheuens Sarah	MA	O	Chief Me	2	M.d	228	34.47	7	12	62	D
10/29/25 16:02	10/27/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gheuens Sarah	MA	O	Chief Me	2	S.d	-228	34.47	-7		62	D
10/29/25 08:54	10/28/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goeltz II Robert C.	CA	O	CFO	1	S	-100	20.00	-5		92	D
10/29/25 08:00	10/23/25	NVCT	Nuvectis Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mosseri Marlio Charles	N1	T		1	P.m	957	6.18	155	5	3,246	I
10/28/25 21:05	9/4/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ra Capital Management, L.P.	MA	DT		3	P.m	74,763	6.84	10,925	66	27,598	I
10/28/25 19:51	10/28/25	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mancini Marianna	CA	O	COO	1	S	-216	35.00	-6		382	D
10/28/25 19:49	10/27/25	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rowland Charles A Jr	CA	D		1	S.d	-2,134	35.57	-60		30	D
10/28/25 19:48	10/28/25	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lian Brian	CA	DO	P,CEO	1	S	-1,365	35.01	-39		2,419	D
10/28/25 19:47	10/28/25	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zante Greg	CA	O	CFO	1	S	-216	35.00	-6		174	D
10/28/25 18:45	10/24/25	RNTX	Rein Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Voss Capital, LP	TX	T		1	P.m	423	1.38	306	30	1,322	I
10/28/25 18:00	10/24/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ong Yee Lung	N8	T		2	S	-854	5.49	-156		269	D
10/28/25 17:00	10/24/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szot Matthew K	FL	O	CFO	6	S.m	-328	14.03	-23		31	D
10/28/25 17:00	10/24/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pham Quang X	FL	DOT	CEO,CB	6	S.m	-312	14.04	-22		413	D
10/28/25 16:30	10/27/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	18	M.dm	113,059	287.86	393		3	I
10/28/25 16:30	10/27/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	18	S.dm	-113,059	287.86	-393		3	I
10/28/25 16:10	10/25/25	MRSN	Mersana Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bala Mohan	MA	O	SVP,Chie	2	M.d	1	2.33	0	13	3	D
10/28/25 16:10	10/27/25	MRSN	Mersana Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bala Mohan	MA	O	SVP,Chie	2	S.d	-1	2.33	0		3	D
10/28/25 08:03	10/24/25	MBX	Mbx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hawryluk P. Kent	IN	DO	P,CEO	2	M.d	867	4.27	203	22	1,133	D
10/27/25 21:30	10/23/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaplan Myron	NJ	D		1	P	276	11.02	25	12	231	D
10/27/25 19:56	10/27/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	5	M.d	595	17.94	33	19	206	D
10/27/25 19:56	10/27/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	5	S.d	-595	17.94	-33		206	D
10/27/25 19:24	10/23/25	RANI	Rani Therapeutics Holdings, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Imran Mir A	CA	DT		1	P.d	1,260	0.6050	2,083	9	24,818	D
10/27/25 17:59	10/27/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Wierenga Wendell	CA	D		2	M.d	300	34.34	9	37	32	D
10/27/25 17:59	10/27/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Wierenga Wendell	CA	D		2	S.d	-300	34.34	-9		32	D
10/27/25 17:19	10/23/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		4	S.d	-12,892	1.01	-12,806		14,447	I
10/27/25 16:30	10/23/25	VRDN	Viridian Therapeutics, Inc.De	DE	Health	Drug	Pharmaceutical Preparations	Fairmount Funds Management LLC	PA	DT		2	P	16,008	20.77	771	14	6,123	I
10/27/25 16:23	10/24/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohen Yuval	MA	DO	CEO	2	M.dm	589	10.66	55	67	138	D
10/27/25 16:23	10/24/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohen Yuval	MA	DO	CEO	2	S.dm	-589	10.66	-55		138	D
10/27/25 16:22	10/24/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moran Sean F.	MA	O	CFO	2	M.d	276	10.64	26	55	73	D
10/27/25 16:22	10/24/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moran Sean F.	MA	O	CFO	2	S.d	-276	10.64	-26		73	D
10/27/25 16:15	10/23/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Third Rock Ventures Iv, L.P.	MA	T		6	S.m	-26,351	7.59	-3,473		15,759	D
10/24/25 20:18	10/22/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	10X Fund, L.P.	GA	T		1	S	-247	4.94	-50		5,872	D
10/24/25 20:00	10/23/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Iwicki Mark T	MA	D		1	S	-125	0.8100	-155		104	D
10/24/25 20:00	10/22/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Reumuth Mary	MA	O	CFO	1	S.m	-28	0.8297	-33		29	D
10/24/25 20:00	10/22/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bazemore Todd	MA	D		1	S	-40	0.8300	-48		36	D
10/24/25 20:00	10/22/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brazzell Romulus K	MA	O	SEE REMA	1	S	-39	0.8300	-47		36	D
10/24/25 20:00	10/22/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kharabi Darius	MA	O	CHIEF BU	1	S	-17	0.8300	-21		42	D
10/24/25 19:19	6/6/25	BOLT	Bolt Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nemec Sarah	CA	O	SVP,Fina	1	P	1	5.50	0	1	24	D
10/24/25 19:18	6/6/25	BOLT	Bolt Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quinn William P.	CA	DO	P,CEO,CF	1	P	1	5.50	0	0	42	D
10/24/25 16:56	10/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	12	M.d	4,586	30.92	148		39	D
10/24/25 16:56	10/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	12	S.d	-4,586	30.92	-148		39	D
10/24/25 16:30	10/23/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McGrath Lynne Fahey	GA	D		1	S	0	2.30	0		0	D
10/24/25 16:01	10/22/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ai Dmi LLC	NY	T		1	S	-59,873	80.47	-744		2,814	D
10/23/25 21:06	10/21/25	SMMT	Summit Therapeutics Inc.		Health	Drug	Pharmaceutical Preparations	Xia Yu	FL	D		1	P	10,000	18.74	534	2	32,057	I
10/23/25 21:03	10/23/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chaudhary Zuraiz	CA	O	See Rema	1	P	25	4.95	5		5	D
10/23/25 21:01	10/23/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Golden Arthur F	CA	D		1	P	100	4.95	20	202	30	D
10/23/25 19:49	10/21/25	NEUP	Neuphoria Therapeutics Inc.	C3	Health	Drug	Pharmaceutical Preparations	Lynx1 Capital Management LP	PR	T		1	P	3,283	5.14	639	271	875	I
10/23/25 18:00	10/21/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fitters Diversified Berhad	N8	T		5	S	-1,777	4.23	-420		557	D
10/23/25 17:10	10/22/25	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Martins Ryan	CA	O	CFO	1	M.d	256	3.17	81	31	339	D
10/23/25 16:20	10/21/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sullivan Timothy Eugene	MA	O	CFO	4	M.d	1,721	22.14	78	83	171	D
10/23/25 16:20	10/21/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sullivan Timothy Eugene	MA	O	CFO	4	S.d	-1,721	22.14	-78		171	D
10/23/25 16:08	9/10/25	SMMT	Summit Therapeutics Inc.		Health	Drug	Pharmaceutical Preparations	Duggan Robert W	FL	DOT	Co-CEO	2	P.m	6,485	17.76	365	0	606,106	D
10/23/25 16:06	9/10/25	SMMT	Summit Therapeutics Inc.		Health	Drug	Pharmaceutical Preparations	Zanganeh Mahkam	FL	DOT	Co-CEO	2	P.m	6,485	17.76	365	0	606,106	I
10/22/25 19:20	10/20/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	5	S.m	-771	20.56	-38		940	I
10/22/25 18:57	10/20/25	RANI	Rani Therapeutics Holdings, Inc.	CA	Health	Drug	Pharmaceutical Preparations	South Cone Investments Limited Partnership	F3	T		1	S.m	-15,711	2.65	-5,923		2,379	I
10/22/25 17:39	8/26/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cloonan Michael	MA	DO	P,CEO	10	M.dm	7,550	18.87	400	271	547	D
10/22/25 17:39	8/26/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cloonan Michael	MA	DO	P,CEO	10	S.dm	-7,550	18.87	-400		547	D
10/22/25 17:09	10/20/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Patel Sanj K	X0	DO	CB,CEO	3	M.dm	11,004	20.18	545		222	D
10/22/25 17:09	10/20/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Patel Sanj K	X0	DO	CB,CEO	3	S.dm	-11,004	20.18	-545		222	D
10/22/25 17:06	10/20/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Megna Michael R	X0	O	CHIEF AC	7	M.dm	3,814	24.49	156		38	D
10/22/25 17:06	10/20/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Megna Michael R	X0	O	CHIEF AC	7	S.dm	-3,814	24.49	-156		38	D
10/22/25 16:32	10/20/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Miller Deborah Ann	MA	O	GC	4	M.dm	3,242	49.12	66		49	D
10/22/25 16:32	10/20/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Miller Deborah Ann	MA	O	GC	4	S.dm	-3,242	49.12	-66		49	D
10/22/25 16:15	10/20/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gharib Samir M.	CA	O	P,CFO	1	M.d	0	0.00	2	51	6	D
10/22/25 16:15	10/20/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szwarcberg Javier B.	CA	DO	CEO	1	M.d	0	0.00	5	102	9	D
10/21/25 18:18	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	12	M.d	722	29.84	24	21	141	D
10/21/25 18:18	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	12	S.d	-722	29.84	-24		141	D
10/21/25 18:13	10/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	6	S.m	-763	20.35	-38		929	I
10/21/25 17:12	10/21/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Booth Bruce	MA	D		5	S.m	-22,086	31.62	-698		3,615	I
10/21/25 16:54	10/20/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Altmeyer Anne	MA	D		2	M.d	27	12.65	2	52	6	D
10/21/25 16:54	10/20/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Altmeyer Anne	MA	D		2	S.d	-27	12.65	-2		6	D
10/21/25 11:56	10/19/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Forbes William P	NC	O	EVP,Chie	2	M.d	0	0.00	16	11	155	D
10/21/25 11:42	10/19/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Duarte IRA	NC	O	EVP,CFO	2	M.d	0	0.00	16	10	168	D
10/21/25 11:23	10/19/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Collard Craig A	NC	DO	CEO	2	M.d	0	0.00	49	11	488	D
10/20/25 20:00	9/12/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		17	S.m	-2,020	2.36	-855		4,488	I
10/20/25 19:13	10/17/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Reed John C	NJ	O	EVP,Inno	2	M.d	7,616	175.31	43		11	D
10/20/25 19:13	10/17/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Reed John C	NJ	O	EVP,Inno	2	S.d	-7,616	175.31	-43		11	D
10/20/25 18:58	10/16/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	Cooperatieve Gilde Healthcare IV U.A.	P7	T		3	S.m	-5,141	1.48	-3,473		5,294	D
10/20/25 18:00	10/15/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kua Khai Loon	N8	T		3	S.m	-815	5.03	-162		385	D
10/20/25 16:44	10/17/25	MBX	Mbx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hoerter Steven L.	IN	D		1	P	265	13.25	20		20	I
10/20/25 09:11	10/17/25	GOVX	Geovax Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Spencer John N Jr	GA	D		1	P	5	0.5498	10	88	21	D
10/17/25 21:00	10/15/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	10	M.dm	81,836	12.11	6,758		1,654	D
10/17/25 21:00	10/15/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	10	S.dm	-81,836	12.11	-6,758		1,654	D
10/17/25 17:53	9/12/25	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Pontifax Management 4 G.P. (2015) Ltd.	L3	T		2	P.d	99,975	17.27	5,787		1,422	I
10/17/25 16:41	10/15/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		5	S.m	-16,488	75.48	-218		1,097	I
10/17/25 16:32	8/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	6	M.d	8,152	50.32	162	186	249	D
10/17/25 16:32	8/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	6	S.d	-8,152	50.32	-162		249	D
10/17/25 16:31	8/29/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	9	M.dm	3,975	55.21	72		66	D
10/17/25 16:31	10/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	8	M.dm	8,767	49.10	179		62	D
10/17/25 16:31	10/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	8	S.dm	-8,767	49.10	-179		62	D
10/17/25 16:28	10/16/25	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dugan Margaret	NY	O	Chief Me	1	S	-29	21.07	-1		25	D
10/17/25 16:27	10/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Teresa	CA	O	CHRO	6	M.d	3,095	34.39	90	999%	97	D
10/17/25 16:27	10/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Teresa	CA	O	CHRO	6	S.d	-3,095	34.39	-90		97	D
10/17/25 16:15	10/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	4	S	-910	26.01	-35		204	D
10/17/25 16:10	10/16/25	PRAX	Praxis Precision Medicines, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Adage Capital Management, L.P.	MA	T		1	S	-33,198	105.76	-314		4,422	I
10/17/25 16:05	10/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	Samayoa Phillip	MA	O	CHIEF SC	1	M.d	0	0.00	0	1	14	D
10/17/25 16:05	10/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	McDonough Geoff	MA	DO	P,CEO	1	M.d	0	0.00	1	0	187	D
10/17/25 16:05	10/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	Howze Yalonda	MA	O	GC	1	M.d	0	0.00	0	17	2	D
10/17/25 16:05	10/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	Paone Antoinette	MA	O	COO	1	M.d	0	0.00	0	5	4	D
10/17/25 16:05	10/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	Conway Kevin John	MA	O	CFO	1	M.d	0	0.00	0	3	2	D
10/17/25 14:01	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jung Cassie	NJ	O	COO	4	M.d	959	4.68	205	254	285	D
10/17/25 14:01	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jung Cassie	NJ	O	COO	4	S.d	-959	4.68	-205		285	D
10/17/25 14:01	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kraus Carl N	NJ	O	Chief Me	1	S	-142	7.00	-20		282	D
10/17/25 14:00	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Boyd Peter E.	NJ	O	See Rema	3	S	-213	6.07	-35		288	D
10/16/25 20:16	10/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	6	M.dm	4,281	59.14	72		37	I
10/16/25 20:16	10/16/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	6	S.dm	-4,281	59.14	-72		37	I
10/16/25 20:16	10/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Parshall B Lynne	CA	D		3	S	-1,587	52.89	-30		86	D
10/16/25 20:16	10/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	4	M.dm	1,129	50.38	22		17	D
10/16/25 20:16	10/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	4	S.dm	-1,129	50.38	-22		17	D
10/16/25 20:15	10/14/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Birchler Brian	CA	O	EVP,Corp	2	M.dm	3,009	62.95	48	530	57	D
10/16/25 20:15	10/14/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Birchler Brian	CA	O	EVP,Corp	2	S.dm	-3,009	62.95	-48		57	D
10/16/25 18:14	10/15/25	AARD	Aardvark Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lee Tien-Li	CA	DOT	CEO	4	M.dm	335	6.93	48	2	3,019	D
10/16/25 18:12	10/15/25	AARD	Aardvark Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jones Bryan	CA	O	COO	1	M.d	5	4.24	1		1	D
10/16/25 16:41	10/15/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	4	M.dm	1,290	12.53	103	103	203	D
10/16/25 16:41	10/15/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	4	S.dm	-1,290	12.53	-103		203	D
10/16/25 16:35	10/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	14	M.dm	16,140	24.40	661		50	D
10/16/25 16:35	10/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	14	S.dm	-16,140	24.40	-661		50	D
10/16/25 16:30	10/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	3	S	-552	21.66	-26		427	D
10/16/25 16:30	9/4/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ceesay Abraham	MA	DO	CEO	3	S	-2,357	26.28	-90		722	D
10/16/25 16:21	10/7/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	Glessner Coleen	MD	O	EVP,Qual	1	S	-306	10.00	-31		144	D
10/16/25 16:15	10/16/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seshadri Vishwas	OH	DO	CEO	2	S.m	-236	5.31	-45		1,190	D
10/16/25 16:13	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	8	M.dm	1,548	13.34	116		111	D
10/16/25 16:13	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	8	S.dm	-1,548	13.34	-116		111	D
10/16/25 16:01	10/14/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Militello John	NJ	O	See Rema	3	S.m	-139	3.76	-37		67	D
10/15/25 20:12	10/10/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunlop A. Sinclair	MA	D		3	S	-2,153	23.08	-93		223	M
10/15/25 19:04	10/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levy Adam Scott	PA	O	CFO,Secr	1	S	-452	42.01	-11		117	D
10/15/25 19:04	10/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Congleton Jon	PA	DO	CEO	1	S	-644	42.67	-15		831	D
10/15/25 19:04	10/15/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	4	S.d	-1,009	25.58	-39		93	D
10/15/25 18:47	10/15/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Hopkinson Craig C.	MA	O	EVP R,D,	2	M.d	380	27.18	14	23	74	D
10/15/25 18:47	10/15/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Hopkinson Craig C.	MA	O	EVP R,D,	2	S.d	-380	27.18	-14		74	D
10/15/25 18:31	10/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		6	M.d	604	45.76	13		0	D
10/15/25 18:31	10/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		6	S.d	-604	45.76	-13	-100	0	D
10/15/25 18:00	10/13/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazumdar Claire	MA	DO	CEO	2	M.dm	561	11.33	49	19	310	D
10/15/25 18:00	10/13/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazumdar Claire	MA	DO	CEO	2	S.dm	-561	11.33	-49		310	D
10/15/25 17:15	10/14/25	QNRX	Quoin Pharmaceuticals, Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Langer Dennis	VA	D		1	P.d	129	8.49	15	999%	15	D
10/15/25 16:36	10/10/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	4	M.d	214	14.29	15	3	595	D
10/15/25 16:36	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	4	S.d	-214	14.29	-15		595	D
10/15/25 16:34	10/10/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	6	M.d	1,429	20.15	71	23	376	D
10/15/25 16:34	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	6	S.d	-1,429	20.15	-71		376	D
10/15/25 16:34	10/10/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	4	M.d	2,138	26.54	81	108	155	D
10/15/25 16:34	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	4	S.d	-2,138	26.54	-81		155	D
10/15/25 16:33	10/10/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	3	M.d	682	23.63	29	13	250	D
10/15/25 16:33	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	3	S.d	-682	23.63	-29		250	D
10/15/25 16:32	10/6/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parkman Healthcare Partners LLC	CT	T		4	P	19	18.53	1	999%	1	I
10/15/25 16:32	10/6/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parkman Healthcare Partners LLC	CT	T		4	S	-19	18.53	-1		1	I
10/15/25 16:31	9/2/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	5	S.dm	-13,848	96.00	-144		2,752	D
10/15/25 16:30	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Krepp Sarah	NC	O	Chief Hu	2	S	-46	24.03	-2		143	D
10/15/25 13:24	10/15/25	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Adar1 Capital Management, LLC	TX	T		1	S	-95,659	17.75	-5,389	-100	0	I
10/14/25 20:11	10/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	6	M.dm	5,201	27.53	189	56	526	D
10/14/25 20:11	10/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	6	S.dm	-5,201	27.53	-189		526	D
10/14/25 19:49	10/13/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	3	S	-111	92.46	-1		76	D
10/14/25 17:16	10/9/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nunn Jason Raleigh	PA	D		1	P	1,200	19.00	63	2	3,120	I
10/14/25 17:14	10/9/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sr One Capital Management, LLC	PA	T		1	P	2,400	19.00	126	3	5,038	I
10/14/25 16:31	10/9/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Bunn Paul A.	MA	D		1	S	-75	9.06	-8		8	D
10/14/25 16:01	10/10/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Waddill William D.	CA	D		4	M.d	1,557	48.66	32		9	D
10/14/25 16:01	10/10/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Waddill William D.	CA	D		4	S.d	-1,557	48.66	-32		9	D
10/14/25 16:00	10/10/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		12	S	-982,956	816.64	-1,204		95,630	D
10/14/25 12:15	10/13/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Horn Howard	CA	O	CFO	1	S	-250	31.51	-8		98	D
10/14/25 08:59	10/9/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Enright Patrick G	MA	D		1	P	2,250	19.19	117	5	2,619	M
10/10/25 19:48	10/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Graham G. Walmsley	CA	D		1	M.d	1,866	20.55	91	8	1,293	D
10/10/25 19:17	10/10/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McFarlane Neil F.	FL	DO	P,CEO	2	M.d	211	3.03	70	46	222	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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