Pharmaceutical Preparations Industry - Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
12/16/25 18:59	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	28	M.dm	240	2.14	112		6	D
12/16/25 18:59	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	28	S.dm	-240	2.14	-112		6	D
12/16/25 18:36	12/12/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Espinoza Octavio	FL	O	CFO	1	S	-340	188.31	-2		26	D
12/16/25 18:34	12/15/25	SILO	Silo Pharma, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Weisblum Eric	FL	DO	CEO	3	P.m	8	0.4030	19	10	217	D
12/16/25 18:27	12/12/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	7	M.dm	19,237	45.60	422	8	5,697	D
12/16/25 18:27	12/15/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	7	S.dm	-19,237	45.60	-422		5,697	D
12/16/25 18:00	12/12/25	CLRB	Cellectar Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Neis John	NJ	D		1	S	-1	3.70	0		0	I
12/16/25 17:41	12/15/25	SXTP	60 Degrees Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dow Geoffrey S	DC	DO	P,CEO	2	P.m	20	0.8820	23	61	60	D
12/16/25 17:09	12/15/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Edgemond James	MD	O	CFO,TREA	14	M.d	79,261	305.99	259		8	D
12/16/25 17:09	12/15/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Edgemond James	MD	O	CFO,TREA	14	S.d	-79,261	305.99	-259		8	D
12/16/25 17:08	12/15/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	64	M.edm	145,366	283.92	512	386	644	D
12/16/25 17:08	12/15/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	64	S.edm	-145,366	283.92	-512		644	D
12/16/25 17:07	12/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	3	S	-688	27.00	-26		410	D
12/16/25 17:00	12/12/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harper Molly	FL	D		4	M.d	738	15.02	49		9	D
12/16/25 17:00	12/12/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harper Molly	FL	D		4	S.d	-738	15.02	-49		9	D
12/16/25 16:52	12/15/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	8	M.dm	1,810	12.57	144	246	203	D
12/16/25 16:52	12/15/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	8	S.dm	-1,810	12.57	-144		203	D
12/16/25 16:42	12/12/25	ELAN	Elanco Animal Health Inc		Health	Drug	Pharmaceutical Preparations	Kurzius Lawrence Erik	IN	D		1	P	213	21.30	10	8	132	D
12/16/25 16:33	12/15/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	26	M.d	176,825	302.26	585		3	I
12/16/25 16:33	12/15/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	26	S.d	-176,825	302.26	-585	-100	3	I
12/16/25 16:30	12/15/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Patusky Christopher	MD	D		2	M.d	598	298.88	2	339	3	D
12/16/25 16:30	12/15/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Patusky Christopher	MD	D		2	S.d	-598	298.88	-2		3	D
12/16/25 16:30	12/12/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bensen Daniel	CA	O	Chief Di	3	S.m	-4,320	16.30	-265		297	D
12/16/25 16:29	12/16/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	14	M.d	1,059	35.31	30	27	141	D
12/16/25 16:29	12/16/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	14	S.d	-1,059	35.31	-30		141	D
12/16/25 16:23	12/15/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Calvin Sandra	CA	O	SVP,Chie	3	S.d	-3,992	30.41	-131		49	D
12/16/25 16:22	12/12/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Shlevin Harold H.	GA	D		4	M.dm	1,741	4.31	404		31	D
12/16/25 16:22	12/12/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Shlevin Harold H.	GA	D		4	S.dm	-1,741	4.31	-404		31	D
12/16/25 16:16	12/12/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Kindler Jeffrey B	MD	D		2	S.m	-1,460	3.56	-410		346	D
12/16/25 16:05	12/12/25	SLGL	Sol-Gel Technologies Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		5	P.m	536	37.13	14	4	382	I
12/16/25 14:59	12/12/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	Yates Bryant J	UT	O	EVP,P,Eu	2	S	-38	6.72	-6		100	D
12/16/25 13:14	12/15/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Anzalone Christopher Richard	CA	DO	CEO	1	S.m	-12,349	67.00	-184		3,917	D
12/16/25 09:30	12/15/25	RLMD	Relmada Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Traversa Sergio	FL	DO	CEO	2	P.d	713	2.38	300	30	1,300	D
12/16/25 09:30	12/15/25	RLMD	Relmada Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Shenouda Maged	FL	O	CFO	2	P.d	1,148	2.24	512	177	800	D
12/16/25 08:56	12/15/25	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	Titterton Lewis H Jr	CA	D		1	M.d	47	2.92	16	2	969	D
12/15/25 21:34	12/11/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Ramaswamy Vivek	DC	T		3	M.dm	199,395	16.17	12,333	36	47,012	D
12/15/25 21:34	12/11/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Ramaswamy Vivek	DC	T		3	S.dm	-199,395	16.17	-12,333		47,012	D
12/15/25 20:07	12/11/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Enright Patrick G	CA	D		2	P	2,500	20.30	123	2	8,019	D
12/15/25 20:02	12/14/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mehta Vimal	CT	DO	CEO,P	1	M.dm	0	0.00	0	0	501	D
12/15/25 20:01	12/14/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Steinhart Richard I	CT	O	CFO	1	M.dm	0	0.00	0	1	7	D
12/15/25 20:01	12/14/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodriguez Javier	CT	O	See Rema	1	M.dm	0	0.00	0	1	7	D
12/15/25 20:00	12/14/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yocca Frank	CT	O	Chief Sc	1	M.dm	0	0.00	0	1	6	D
12/15/25 19:55	11/7/25	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ra Capital Management, L.P.	MA	DT		8	P.dm	130,602	8.34	15,656	38	56,638	I
12/15/25 19:35	12/15/25	RZLT	Rezolute, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Evans Daron	CA	O	CFO	1	P	80	1.77	45	10	513	M
12/15/25 19:35	12/2/25	RZLT	Rezolute, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Elam Nevan C	CA	DO	CEO	2	M.d	59	1.57	38	6	708	D
12/15/25 19:34	12/15/25	RZLT	Rezolute, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Karnawat Sunil Ratilal	CA	O	Chief Co	1	P	20	1.62	12	17	81	D
12/15/25 17:49	12/11/25	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	Quisel John D	MA	DO	CEO	2	M.d	4,116	51.45	80	87	172	D
12/15/25 17:49	12/11/25	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	Quisel John D	MA	DO	CEO	2	S.d	-4,116	51.45	-80		172	D
12/15/25 17:39	12/12/25	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zedelmayer Christine	CA	O	SVP,COO	2	S.m	-55	1.26	-44		127	D
12/15/25 17:24	12/12/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Bormann-Kennedy Barbara-Jean Anne	IL	D		1	S	-106	7.09	-15		143	D
12/15/25 17:24	12/15/25	ZNTL	Zentalis Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Matrix Capital Management Company, LP	MA	T		1	S	-9,975	1.33	-7,500		6,460	I
12/15/25 17:17	12/11/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Petersen Floyd F.	CA	D		5	S.dm	-854	22.17	-39		76	D
12/15/25 16:51	12/11/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	Bendheim Jack	NJ	DOT	P,CEO	15	S.dm	-8,714	42.68	-204		91	I
12/15/25 16:43	12/11/25	ELAN	Elanco Animal Health Inc		Health	Drug	Pharmaceutical Preparations	Modi Rajeev A.	IN	O	SEE REMA	1	P	96	21.33	5	4	123	D
12/15/25 16:42	12/11/25	ELAN	Elanco Animal Health Inc		Health	Drug	Pharmaceutical Preparations	Vanhimbergen Robert M	IN	O	EVP,CFO	1	P	150	21.64	7	6	124	D
12/15/25 16:41	12/11/25	ELAN	Elanco Animal Health Inc		Health	Drug	Pharmaceutical Preparations	Simmons Jeffrey N	IN	DO	P,CEO,Di	1	P	478	21.75	22	1	1,969	I
12/15/25 16:38	12/12/25	OGEN	Oragenics Inc	FL	Health	Drug	Pharmaceutical Preparations	Telling Fred	FL	D		1	S.d	0	0.9429	0		35	D
12/15/25 16:32	12/11/25	WVE	Wave Life Sciences Ltd.	X0	Health	Drug	Pharmaceutical Preparations	Gsk Plc	X0	T		1	P	27,930	19.00	1,470	9	18,246	I
12/15/25 16:30	12/11/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	6	M.dm	3,434	58.07	59		21	D
12/15/25 16:30	12/11/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	6	S.dm	-3,434	58.07	-59		21	D
12/15/25 16:18	12/11/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cormorant Asset Management, LP	MA	T		1	S	-344	11.46	-30		2,345	I
12/15/25 16:15	12/11/25	BMEA	Biomea Fusion, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Erdtmann Rainer M	CA	DO	See Rema	2	P.m	98	1.22	80	3	2,573	D
12/12/25 20:30	12/11/25	AARD	Aardvark Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sun Nelson	CA	O	CFO	1	P	43	14.40	3	3	108	D
12/12/25 20:30	12/11/25	AARD	Aardvark Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lee Tien-Li	CA	DOT	CEO	2	P.d	107	12.95	8	0	3,026	D
12/12/25 19:05	12/10/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gharib Samir M.	CA	O	P,CFO	2	M.dm	0	0.00	4	142	8	D
12/12/25 19:03	12/10/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szwarcberg Javier B.	CA	DO	CEO	2	M.dm	0	0.00	11	529	13	D
12/12/25 18:00	12/12/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chaudhary Zuraiz	CA	O	See Rema	4	P.m	50	3.99	13		13	D
12/12/25 17:32	10/27/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Evnin Luke	MA	D		11	S.m	-1,610	1.13	-1,420		4,133	I
12/12/25 17:30	12/10/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Mandalam Ramkumar	TN	D		1	S	-116	9.99	-12		81	D
12/12/25 17:17	12/12/25	IMVT	Immunovant, Inc.	D0	Health	Drug	Pharmaceutical Preparations	Roivant Sciences Ltd.	X0	DT		1	P	350,000	21.00	16,667	17	113,317	D
12/12/25 17:06	12/10/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Paterson Dan	MA	DO	P,CEO	7	S.m	-323	10.18	-32		442	D
12/12/25 16:56	12/10/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	6	M.dm	6,636	281.77	24	12	223	D
12/12/25 16:56	12/10/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	6	S.dm	-6,636	281.77	-24		223	D
12/12/25 16:40	12/10/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedman Paul A	PA	D		2	M.d	14,086	283.99	50	6	843	D
12/12/25 16:40	12/10/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedman Paul A	PA	D		2	S.d	-14,086	283.99	-50		843	D
12/12/25 16:35	12/10/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taub Rebecca	PA	D		2	M.d	10,592	283.97	37	3	1,111	D
12/12/25 16:35	12/10/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taub Rebecca	PA	D		2	S.d	-10,592	283.97	-37		1,111	D
12/12/25 16:32	12/11/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Malcolm Jan	MD	D		1	S	-24	482.98	0		0	D
12/12/25 16:32	12/11/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	14	M.d	45,305	294.19	154		37	D
12/12/25 16:32	12/11/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	14	S.d	-45,305	294.19	-154		37	D
12/12/25 07:16	12/11/25	FBLG	Fibrobiologics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Garcia Ruben A	TX	O	GC	1	P	48	0.3400	140		140	D
12/11/25 21:47	12/9/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cross Shawn	CA	O	CFO	3	M.dm	1,304	21.02	62		56	D
12/11/25 21:47	12/9/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cross Shawn	CA	O	CFO	3	S.dm	-1,304	21.02	-62		56	D
12/11/25 21:00	12/9/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	12	M.dm	90,033	12.24	7,358		1,505	D
12/11/25 21:00	12/9/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	12	S.dm	-90,033	12.24	-7,358		1,505	D
12/11/25 20:50	8/21/25	GNLX	Genelux Corp	DE	Health	Drug	Pharmaceutical Preparations	Yu Yong	CA	O	SVP,Clin	1	S.m	-16	3.82	-4		146	D
12/11/25 20:50	8/21/25	GNLX	Genelux Corp	DE	Health	Drug	Pharmaceutical Preparations	Zindrick Thomas	CA	O	P,CEO	1	S.m	-66	3.86	-17		538	D
12/11/25 20:49	8/21/25	GNLX	Genelux Corp	DE	Health	Drug	Pharmaceutical Preparations	Cappello Joseph	CA	O	Chief Te	1	S.m	-14	3.88	-4		156	D
12/11/25 17:35	12/9/25	IRD	Opus Genetics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Foundation Fighting Blindness Retinal Degeneration Fund	NC	DH	See Rema	1	S	-8,600	2.15	-4,000		5,492	D
12/11/25 17:19	12/9/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	Henderson Mary Elizabeth	L2	O	SVP,Tech	1	S	-379	169.51	-2		20	D
12/11/25 16:27	12/9/25	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	Yancopoulos George	NY	DO	Bd. Co-C	1	M.d	81,581	555.67	147	15	1,126	D
12/11/25 16:23	12/9/25	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	Schleifer Leonard S	NY	DO	Bd. Co-C	1	M.d	95,977	555.67	173	34	688	D
12/11/25 16:21	12/9/25	BIOA	Bioage Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rubin Paul D	CA	O	Chief Me	4	M.d	1,319	7.59	174		0	D
12/11/25 16:21	12/9/25	BIOA	Bioage Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rubin Paul D	CA	O	Chief Me	4	S.d	-1,319	7.59	-174	-100	0	D
12/11/25 16:09	12/9/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Daniell Richard	L3	O	EVP,Euro	2	M.d	5,436	23.54	231		48	D
12/11/25 16:09	12/9/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Daniell Richard	L3	O	EVP,Euro	2	S.d	-5,436	23.54	-231		48	D
12/11/25 16:06	12/9/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Sabag Mark	L3	O	See "Rem	2	M.d	8,440	25.15	336		53	D
12/11/25 16:06	12/9/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Sabag Mark	L3	O	See "Rem	2	S.d	-8,440	25.15	-336		53	D
12/11/25 12:10	12/10/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Horn Howard	CA	O	CFO	2	S	-362	32.87	-11		98	D
12/11/25 08:38	12/9/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dillione Janet	NJ	D		7	M.d	2,025	8.30	244		48	D
12/11/25 08:38	12/9/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dillione Janet	NJ	D		7	S.d	-2,025	8.30	-244		48	D
12/11/25 08:31	12/10/25	APRE	Aprea Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Duey Marc	PA	D		1	P.d	25	1.17	21	9	257	D
12/11/25 08:31	12/10/25	APRE	Aprea Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hamill John P.	PA	O	SrVP,CFO	1	P.d	6	1.17	5	22	28	D
12/10/25 21:45	12/8/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Rawcliffe Adrian	MA	D		3	M.d	990	9.89	100		13	D
12/10/25 21:45	12/8/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Rawcliffe Adrian	MA	D		3	S.d	-990	9.89	-100		13	D
12/10/25 21:45	12/8/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Wagner Heidi L	MA	D		2	M.d	273	9.74	28	165	45	D
12/10/25 21:45	12/8/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Wagner Heidi L	MA	D		2	S.d	-273	9.74	-28		45	D
12/10/25 21:45	12/8/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Henry Christian O	MA	D		2	S.d	-1,810	10.03	-180		13	D
12/10/25 21:45	12/8/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Henry Christian O	MA	D		2	M.d	1,810	10.03	180		13	D
12/10/25 21:45	12/8/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Tan Aik Na	MA	D		2	S.d	-2,401	9.48	-253		25	D
12/10/25 21:45	12/8/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Tan Aik Na	MA	D		2	M.d	2,401	9.48	253		25	D
12/10/25 21:45	12/8/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Verdine Gregory L.	MA	D		1	S	-269	13.47	-20		275	D
12/10/25 21:45	12/8/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Francis Chris	MA	O	See Rema	2	M.d	8,534	9.68	882		25	D
12/10/25 21:45	12/8/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Francis Chris	MA	O	See Rema	2	S.d	-8,534	9.68	-882		25	D
12/10/25 21:45	12/8/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Moran Kyle	MA	O	CFO	2	M.dm	5,643	10.15	556		90	D
12/10/25 21:45	12/8/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Moran Kyle	MA	O	CFO	2	S.dm	-5,643	10.15	-556		90	D
12/10/25 21:45	12/8/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Corrigan Mark	MA	D		1	S	-217	13.48	-16		29	D
12/10/25 21:38	12/9/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lefkowitz Steven W	NJ	D		1	S	-475	11.88	-40		113	D
12/10/25 20:51	12/8/25	XCUR	Exicure, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sangsangin Investment & Securities Co., Ltd.	M5	T		1	S	-3,774	8.71	-433	-100	0	D
12/10/25 18:49	12/10/25	IMMX	Immix Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rachman Ilya M	CA	DO	CEO,CB	1	P	5	6.67	1	0	1,142	D
12/10/25 18:48	12/8/25	TENX	Tenax Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rich Stuart	NC	DO	Chief Me	2	P.dm	96	9.64	10	377	13	M
12/10/25 18:47	12/10/25	IMMX	Immix Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Morris Gabriel S	CA	DO	CFO	1	P.d	5	6.58	1	0	742	M
12/10/25 17:45	11/26/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Shuman Harry	P7	O	VP Contr	4	M.d	996	49.82	20		11	D
12/10/25 17:45	11/26/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Shuman Harry	P7	O	VP Contr	4	S.d	-996	49.82	-20		11	D
12/10/25 17:13	12/8/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	3	S	-390	19.51	-20		277	I
12/10/25 17:06	12/8/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Ragosa Mark	X0	O	CFO	6	M.d	3,701	29.45	126		31	D
12/10/25 17:06	12/8/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Ragosa Mark	X0	O	CFO	6	S.d	-3,701	29.45	-126		31	D
12/10/25 17:05	12/9/25	ELTX	Elicio Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Demuth Peter	MA	O	Chief Sc	1	M.d	2	4.41	0	95	1	D
12/10/25 17:00	12/8/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Elsbernd Brian	FL	O	Chief Co	3	M.d	908	17.39	52	28	238	D
12/10/25 17:00	12/8/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Miller Steve	FL	O	Chief Op	2	M.d	0	0.00	20	2	1,080	D
12/10/25 17:00	12/8/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tierney David S	FL	D		2	M.d	0	0.00	2	1	382	D
12/10/25 17:00	12/8/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Thompson Tamar	FL	D		2	M.d	0	0.00	2	167	4	D
12/10/25 17:00	12/8/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Del Carmen Jeffrey	FL	O	Chief Co	4	M.d	302	8.49	36		10	D
12/10/25 17:00	12/8/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McEnany Patrick J	FL	DH	Chairman	2	M.d	0	0.00	5	0	4,283	D
12/10/25 17:00	12/8/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Denkhaus Donald A	FL	D		2	M.d	0	0.00	2	0	497	D
12/10/25 17:00	12/8/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sundaram Preethi	FL	O	Chief St	2	M.d	0	0.00	12	33	51	D
12/10/25 16:56	12/9/25	SNSE	Sensei Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cambrian Biopharma Inc	NY	T		3	S.dm	-290	10.24	-28		161	D
12/10/25 16:56	12/9/25	SNSE	Sensei Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cambrian Biopharma Inc	NY	T		3	M.dm	290	10.24	28	21	161	D
12/10/25 16:54	12/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mesa Nilda	MD	D		1	S	-90	481.63	0		5	D
12/10/25 16:52	12/8/25	SNSE	Sensei Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peyer James	NY	TH	See rema	3	S.dm	-290	10.24	-28		161	I
12/10/25 16:52	12/9/25	SNSE	Sensei Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peyer James	NY	TH	See rema	3	M.dm	290	10.24	28	21	161	I
12/10/25 16:32	12/8/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Dreyer Scott	MA	O	EVP,Chie	2	M.d	1,128	32.04	35	51	104	D
12/10/25 16:32	12/8/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Dreyer Scott	MA	O	EVP,Chie	2	S.d	-1,128	32.04	-35		104	D
12/10/25 16:30	12/8/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	11	S.dm	-12,663	55.76	-227		62	D
12/10/25 16:29	12/8/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	Santos Da Silva Jorge	V8	DO	CEO	1	S.m	-2,975	14.87	-200		2,879	D
12/10/25 16:29	12/8/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	Reich Kristian	V8	O	Chief Sc	1	S.m	-3,012	14.85	-203		2,975	D
12/10/25 16:24	12/8/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Allan Jonathan	MA	O	GC,Corp	7	S.dm	-915	16.14	-57		20	D
12/10/25 16:23	12/8/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	MA	D		14	S.dm	-6,213	26.61	-234		79	D
12/10/25 16:05	12/8/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Turner William D.	CA	O	Chief Re	4	M.d	1,164	29.09	40		23	D
12/10/25 16:05	12/8/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Turner William D.	CA	O	Chief Re	4	S.d	-1,164	29.09	-40		23	D
12/10/25 16:05	12/9/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hasnain Faheem	CA	D		2	M	141	7.05	20	502	24	D
12/10/25 16:05	12/9/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hasnain Faheem	CA	D		2	S	-141	7.05	-20		24	D
12/10/25 07:53	12/8/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Apuli Maricel	CA	O	Chief Ac	1	S	-149	74.26	-2		130	D
12/9/25 20:00	8/21/25	GNLX	Genelux Corp	DE	Health	Drug	Pharmaceutical Preparations	Smalling Ralph	CA	O	Head of	1	S.m	-9	3.75	-2		69	D
12/9/25 19:40	12/5/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	Mortimer Ian	A1	DO	P,CEO,IN	4	S.dm	-2,343	31.12	-75		46	D
12/9/25 19:13	12/5/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	Akkaraju Srinivas	CA	D		6	P.m	9,069	7.17	1,265	28	5,757	I
12/9/25 19:07	12/9/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	5	S.d	-876	23.05	-38		194	D
12/9/25 18:16	12/6/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	8	M.d	371	4.55	81	24	425	D
12/9/25 18:16	12/8/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	8	S.d	-371	4.55	-81		425	D
12/9/25 18:09	12/5/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Tannenbaum Renee P	MN	D		1	S	-146	81.15	-2		25	D
12/9/25 18:04	12/5/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Perry Michael S	CA	D		1	S	-992	61.03	-16		115	D
12/9/25 18:01	12/5/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	Richard Ronald	MD	D		2	S.d	-392	8.22	-48		98	D
12/9/25 18:01	12/5/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	Richard Ronald	MD	D		2	M.d	392	8.22	48	94	98	D
12/9/25 17:35	12/8/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kunkel Lori Anne	CA	D		2	M.d	100	6.42	16	23	84	D
12/9/25 17:25	12/5/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	Carr Patricia	L2	O	SVP,Chie	4	S.d	-3,114	157.85	-20		7	D
12/9/25 17:25	12/5/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	Carr Patricia	L2	O	SVP,Chie	4	M.d	3,114	157.85	20		7	D
12/9/25 17:00	12/5/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Urist Marshall	NY	O	EVP,Rese	2	S	-3,287	39.53	-83		228	M
12/9/25 16:57	12/5/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fitzpatrick Jennifer	MA	O	GC	2	M.d	478	23.32	21		0	D
12/9/25 16:57	12/5/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fitzpatrick Jennifer	MA	O	GC	2	S.d	-478	23.32	-21	-100	0	D
12/9/25 16:51	12/5/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Stan	IL	D		4	P.dm	82	1.12	73	6	1,369	I
12/9/25 16:36	12/5/25	MRVI	Maravai Lifesciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lucier Gregory T	CA	D		1	P.m	369	3.69	100	61	265	D
12/9/25 16:22	12/5/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Balice-Gordon Rita J.	MA	D		1	S	-172	47.03	-4		53	D
12/9/25 16:10	12/5/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kapadia Sandip	PA	O	CFO	4	M.d	1,491	16.87	88		21	D
12/9/25 16:10	12/5/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kapadia Sandip	PA	O	CFO	4	S.d	-1,491	16.87	-88		21	D
12/9/25 16:05	12/5/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Sharoky Melvin Md	NJ	D		1	S	-4,100	205.01	-20		270	D
12/8/25 20:05	12/8/25	ANVS	Annovis Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hoffman Michael B	PA	D		6	P	2,615	2.31	1,134	68	2,798	D
12/8/25 19:38	12/8/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Aryeh Jason	FL	D		2	M.d	1,849	153.69	12	10	128	D
12/8/25 17:28	12/8/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Callos Andrew	CA	O	EVP,Chie	4	M.d	5,347	49.95	107		51	D
12/8/25 17:28	12/8/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Callos Andrew	CA	O	EVP,Chie	4	S.d	-5,347	49.95	-107		51	D
12/8/25 17:15	11/17/25	DMAC	Diamedica Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Stahlberg Jan	V7	T		1	P.m	7,631	7.19	1,061	14	8,826	I
12/8/25 16:30	12/4/25	XOMA	Xoma Royalty Corp	NV	Health	Drug	Pharmaceutical Preparations	Hughes Owen	CA	DO	CEO	2	P.d	2,505	18.48	136	209	201	D
12/8/25 16:30	12/4/25	CBIO	Crescent Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	Fairmount Funds Management LLC	PA	DT		3	P.d	34,246	16.07	2,131	32	8,871	I
12/8/25 16:07	12/4/25	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Barabe Timothy C	MD	D		1	P	206	6.86	30	123	54	D
12/8/25 13:21	12/2/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	10X Fund, L.P.	GA	T		4	S.m	-2,229	5.54	-402		5,872	D
12/8/25 07:00	12/5/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Agah Ramtin	CA	DO	Chief Me	2	P.m	27	0.8500	32	4	766	D
12/5/25 20:51	12/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticho Barry	MA	O	Chief Me	6	M.dm	567	13.31	43		20	D
12/5/25 20:51	12/4/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticho Barry	MA	O	Chief Me	6	S.dm	-567	13.31	-43		20	D
12/5/25 20:00	12/4/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Savitz Ryan	NY	O	CFO,CBO	2	M.d	1,072	26.81	40		0	D
12/5/25 20:00	12/4/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Savitz Ryan	NY	O	CFO,CBO	2	S.d	-1,072	26.81	-40	-100	0	D
12/5/25 18:53	12/5/25	ENTA	Enanta Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	Capps Kathleen S.	MA	O	See Rema	2	S	-7	14.12	-1		9	D
12/5/25 18:47	12/5/25	ENTA	Enanta Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	Trout Harry R. III	MA	O	See Rema	2	S	-13	14.12	-1		17	D
12/5/25 18:46	12/5/25	ENTA	Enanta Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	Rottinghaus Scott T.	MA	O	Chief Me	1	S	-11	14.23	-1		22	D
12/5/25 18:45	12/5/25	ENTA	Enanta Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	Luu Brendan	MA	O	Chief Bu	1	S	-20	14.23	-1		38	D
12/5/25 18:44	12/5/25	ENTA	Enanta Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	Kieffer Tara Lynn	MA	O	Chief Pr	1	S	-30	14.23	-2		31	D
12/5/25 18:43	12/5/25	ENTA	Enanta Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	Or Yat Sun	MA	O	Chief Sc	1	S	-34	14.23	-2		371	D
12/5/25 18:41	12/5/25	ENTA	Enanta Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	Luly Jay R.	MA	DO	P,CEO	1	S	-67	14.23	-5		858	D
12/5/25 18:02	12/3/25	TBPH	Theravance Biopharma, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Farnum Rhonda	CA	O	SVP,COMM	1	S	-583	18.75	-31		278	D
12/5/25 17:01	12/3/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Lloyd George W.	NY	O	EVP,Inve	2	S	-9,568	38.98	-245		1,000	I
12/5/25 16:21	12/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Hopkinson Craig C.	MA	O	EVP R,D,	7	M.d	1,053	26.65	39	115	74	D
12/5/25 16:21	12/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Hopkinson Craig C.	MA	O	EVP R,D,	7	S.d	-1,053	26.65	-39		74	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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