Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
8/1/25 17:09	8/1/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	41	S.d	-3,850	19.83	-194		185	D
8/1/25 16:32	7/30/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	10	41	S.dm	-53,667	55.29	-971		1,984	I
8/1/25 16:30	7/30/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.dm	-634	2.59	-245		96	I
8/1/25 16:30	10/22/24	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	10	78	S.dm	-447,065	87.21	-5,126		23,153	I
8/1/25 16:06	7/30/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	15	44	S.adm	-10,903	38.24	-285		951	D
7/31/25 17:05	7/29/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	9	60	S.dm	-2,744,529	133.72	-20,524		202,510	I
7/31/25 16:38	7/29/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	10	92	S.d	-31,499	49.40	-638		849	D
7/30/25 20:12	7/28/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	24	S.dm	-14,712	13.26	-1,109		10,017	D
7/30/25 17:57	7/28/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	103	S.dm	-65,880	22.51	-2,926		18,360	D
7/30/25 17:00	7/29/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	7	48	S.dm	-22,910	15.67	-1,462		1,877	D
7/30/25 16:56	7/29/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	31	S.m	-1,898	1.04	-1,824		2,920	D
7/30/25 16:31	7/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	9	85	S.d	-7,419	12.94	-573		18,674	D
7/30/25 16:03	7/28/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	2	9	S.d	-681	13.81	-49		200	D
7/30/25 13:47	7/29/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	6	S.d	-207	5.65	-37	-100	0	D
7/29/25 18:56	7/29/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	61	S.dm	-46,222	55.74	-829		449	D
7/29/25 16:52	7/25/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-4	3.65	-1		13	M
7/28/25 18:08	7/25/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	5	21	S.dm	-23,613	46.08	-512		977	D
7/25/25 19:06	7/23/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	32	S.d	-537	5.43	-99		1,500	D
7/25/25 18:56	7/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	13	140	S.dm	-374,458	305.43	-1,226		783	D
7/25/25 16:00	7/24/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	5	43	S.ed	-2,762,863	868.95	-3,180		98,989	D
7/24/25 17:00	7/22/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	7	34	S.dm	-6,384	7.62	-838		1,521	D
7/23/25 21:00	6/18/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	8	24	S.dm	-182,742	11.53	-15,844		186,108	D
7/23/25 18:09	7/22/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-39	0.9200	-43		136	D
7/23/25 17:00	7/22/25	MURA	Mural Oncology Plc	L2	Health	Drug	Pharmaceutical Preparations	4	12	S.dm	-221	3.16	-70		519	D
7/23/25 16:35	7/21/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	8	83	S.dm	-178,609	73.12	-2,443		1,669	D
7/23/25 16:16	7/21/25	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	S	-950	6.72	-141		1,123	D
7/22/25 19:51	7/18/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	28	S.m	-1,464	3.39	-432		8,082	D
7/22/25 17:08	7/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	37	S.dm	-123,032	279.47	-440		2,554	D
7/22/25 16:15	7/22/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	18	S	-1,900	5.77	-330		2,722	D
7/21/25 19:14	7/17/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	7	71	S.dm	-69,584	69.94	-995		4,464	D
7/21/25 16:15	6/25/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	3	5	S.m	-63	0.7047	-89		8,301	D
7/18/25 18:00	7/16/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	94	S.dm	-55,416	38.19	-1,451		1,717	D
7/18/25 16:30	7/16/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-536	13.98	-38		478	D
7/18/25 16:12	8/30/24	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	4	5	S.d	-7,287	161.25	-45		118	D
7/18/25 16:07	7/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	27	S	-176	1.64	-108		3,099	D
7/18/25 16:05	7/17/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	2	9	S.dm	-9,947	55.95	-178		11	D
7/18/25 16:05	7/16/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	12	S	-1,038	9.38	-111		1,599	D
7/18/25 16:02	7/17/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	12	59	S.dm	-18,272	34.60	-528		4,430	D
7/17/25 20:51	7/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	4	21	S.d	-4,055	5.58	-727		5,348	D
7/17/25 18:20	7/15/25	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	S.d	-1,080	9.20	-117		802	D
7/17/25 17:19	7/15/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	6	23	S.dm	-41,905	17.10	-2,450		12,308	D
7/16/25 21:06	7/14/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-2,867	37.80	-76		1,745	D
7/16/25 18:01	7/14/25	TBPH	Theravance Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	1	6	S	-522	10.44	-50		370	D
7/16/25 16:30	7/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	7	40	S.dm	-30,858	25.55	-1,208		478	D
7/16/25 16:20	7/14/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	20	S.d	-322	4.27	-75		826	D
7/16/25 16:14	7/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	5	S	-467	10.99	-43		469	D
7/15/25 16:05	7/10/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	27	S.dm	-6,860	41.12	-167		442	D
7/14/25 16:11	3/19/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	9	44	S.dm	-23,763	63.03	-377		2,096	D
7/14/25 16:02	5/28/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	54	S.dm	-7,667	11.58	-662		2,357	D
7/11/25 18:17	7/10/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	6	17	S.dm	-10,920	97.33	-112		227	D
7/11/25 17:27	3/17/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	24	S.dm	-6,055	11.80	-513		18,096	D
7/10/25 20:56	7/9/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	34	S.d	-3,271	12.35	-265		683	D
7/10/25 16:17	7/8/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-678	0.5084	-1,334		2,300	D
7/8/25 17:55	7/7/25	BRFG	Bullfrog Ai Holdings, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	11	S.m	-620	2.07	-300		2,542	D
7/8/25 16:37	2/19/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	4	21	S.d	-1,909	10.31	-185		1,223	D
7/8/25 16:20	7/3/25	BPMC	Blueprint Medicines Corp	DE	Health	Drug	Pharmaceutical Preparations	12	55	S.dm	-45,104	97.12	-464		832	D
7/8/25 16:05	7/3/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	41	S.dm	-19,639	25.56	-768		3,531	D
7/8/25 16:00	7/3/25	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-15	4.81	-3		6	D
7/7/25 17:20	7/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	9	41	S.dm	-1,327	15.20	-87		1,038	D
7/7/25 16:03	7/3/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-10,333	53.12	-195		172	D
7/3/25 19:51	7/1/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S	-167	1.09	-153		1,212	D
7/3/25 19:39	7/1/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	4	4	S.d	-401	19.07	-21		408	D
7/3/25 18:48	7/2/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	28	S.dm	-10,844	42.52	-255		600	D
7/3/25 17:30	7/2/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	5	22	S.dm	-4,549	44.49	-102		512	D
7/3/25 16:30	7/1/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	25	S.dm	-313,490	39.13	-8,012		30,357	I
7/3/25 16:21	7/1/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	12	68	S.dm	-110,557	13.44	-8,225		55,783	D
7/3/25 16:15	7/2/25	KZR	Kezar Life Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-7	0.9863	-8		36	D
7/3/25 16:07	7/2/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	10	53	S.dm	-20,606	29.78	-692		1,547	D
7/3/25 15:31	5/3/24	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	22	S.d	-88,009	63.96	-1,376		3,010	D
7/3/25 14:56	2/3/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	5	19	S.dm	-6,247	130.60	-48		622	D
7/3/25 14:55	7/1/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	S.dm	-4,681	7.45	-628		7,925	D
7/3/25 13:34	7/2/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	6	15	S.dm	-5,967	25.58	-233		435	D
7/3/25 13:28	7/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	14	S	-118	1.72	-68		716	D
7/2/25 17:28	7/1/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	10	42	S.dm	-7,579	19.01	-399		1,158	D
7/2/25 16:15	6/30/25	PMN	Promis Neurosciences Inc.	Z4	Health	Drug	Pharmaceutical Preparations	1	1	S	0	0.00	-93		2,124	D
7/2/25 16:09	7/1/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	36	S.dm	-127,746	11.67	-10,946		11,111	D
7/2/25 16:07	7/1/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	S.dm	-968	9.46	-102		932	D
7/1/25 21:23	6/27/25	CRVS	Corvus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-9,784	4.16	-2,353		14,330	I
7/1/25 17:01	6/30/25	AKBA	Akebia Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	12	S.d	-1,036	2.17	-478		6,290	D
7/1/25 16:49	6/27/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	13	30	S.dm	-3,049	11.95	-255		1,522	D
7/1/25 16:37	7/19/24	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	13	S.dm	-3,496	6.88	-508		530	D
6/30/25 17:02	6/26/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S.m	-1,141	8.13	-140		331	D
6/27/25 16:27	6/6/24	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	2	4	S.m	-32,936	11.47	-2,871		3,020	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	26	S.d	-597	4.77	-125		597	D
6/25/25 18:52	6/23/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.m	-3,424	1.86	-1,842		1,830	D
6/24/25 16:39	6/20/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	41	S.dm	-800	6.90	-116		721	D
6/24/25 16:08	6/24/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	8	S.m	-913	14.44	-63		1,764	D
6/23/25 19:42	6/20/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	12	S.dm	-22,009	96.10	-229		517	D
6/23/25 13:50	6/20/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	22	S.dm	-10,915	44.57	-245		3,588	D
6/20/25 17:42	6/17/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	15	S.m	-9,029	18.79	-480		10,040	D
6/20/25 16:08	6/18/25	NKTX	Nkarta, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	S	-158	2.74	-58		1,036	D
6/18/25 18:02	6/17/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	60	S.dm	-60,266	37.53	-1,606		1,077	D
6/18/25 17:12	6/16/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-1,186	12.49	-95	-100	0	D
6/18/25 16:31	6/16/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	6	39	S.dm	-61,888	6.40	-9,675		33,938	D
6/18/25 16:11	6/16/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	9	22	S.dm	-52,450	8.34	-6,289		52,475	D
6/17/25 16:11	6/13/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	18	S.dm	-403	1.69	-238		2,075	D
6/16/25 21:10	6/13/25	VNDA	Vanda Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-71	5.00	-14		326	D
6/16/25 19:35	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	11	23	S.dm	-5,082	20.16	-252		989	D
6/16/25 17:47	6/13/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.m	-2,828	26.36	-107		1,202	D
6/16/25 16:56	6/12/25	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.m	-4,097	16.79	-244		3,486	D
6/16/25 16:48	3/28/24	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	37	S.d	-30,685	45.27	-678		1,654	D
6/16/25 16:42	6/13/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	26	S.dm	-12,765	12.56	-1,016		1,658	D
6/16/25 16:03	6/12/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	12	24	S.dm	-37,564	17.58	-2,137		2,193	D
6/16/25 15:40	8/9/24	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	7	S.m	-6,921	1.10	-6,275		3,731	I
6/13/25 20:00	6/13/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	5	11	S.d	-8,731	12.01	-727		692	D
6/13/25 19:57	6/13/25	LTRN	Lantern Pharma Inc.	TX	Health	Drug	Pharmaceutical Preparations	2	7	S.m	-1,190	3.44	-346		2,411	I
6/12/25 17:00	6/10/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	25	S.dm	-49,359	22.15	-2,228		6,066	D
6/11/25 17:04	6/9/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	6	18	S.dm	-13,210	31.93	-414		678	D
6/11/25 16:15	6/9/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	9	S.m	-2,908	30.61	-95		3,960	I
6/10/25 16:39	6/9/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	4	14	S.dm	-20,846	32.75	-636		216	D
6/6/25 17:58	6/5/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	4	4	S.dm	-3,186	40.53	-79		81	D
6/6/25 16:47	6/5/25	KRON	Kronos Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-22	0.8678	-25		139	D
6/6/25 16:07	11/14/24	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	67	S.dm	-120,223	39.70	-3,029		9,645	I
6/5/25 19:25	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	10	S.ad	-7,648	24.85	-308		15,023	M
6/5/25 18:01	6/4/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	6	30	S.d	-3,418	17.28	-198		368	D
6/5/25 17:40	6/4/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	12	S.d	-1,177	26.79	-44		449	D
6/4/25 16:31	6/3/25	ZTS	Zoetis Inc.		Health	Drug	Pharmaceutical Preparations	4	8	S.d	-1,399	170.27	-8		127	D
6/4/25 15:23	6/4/25	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	10	S.m	-44	0.6848	-64	0	15,428	D
6/3/25 18:34	5/29/25	CKPT	Checkpoint Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	9	S.dm	-4,804	3.56	-1,350		5,234	D
6/3/25 16:20	6/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	6	18	S.m	-1,257	7.63	-165		4,686	D
6/3/25 16:10	5/30/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	11	40	S.dm	-88,718	261.70	-339		543	D
6/2/25 18:00	5/29/25	LGVN	Longeveron Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.m	-39	1.33	-30		976	D
6/2/25 16:30	5/30/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	7	S.dm	-3,975	39.01	-102		293	D
5/29/25 16:01	5/27/25	GYRE	Gyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	43	S.dm	-2,549	12.70	-201		2,941	I
5/28/25 20:06	5/23/25	LFCR	Lifecore Biomedical, Inc. De	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.m	-9,871	6.62	-1,491		1,714	I
5/28/25 16:08	5/23/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	8	S	-830	7.90	-105		417	D
5/22/25 21:55	5/20/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	10	67	S.dm	-12,461	6.92	-1,801		4,929	D
5/21/25 20:08	5/19/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	5	20	S.m	-541	1.11	-486		20,379	D
5/21/25 19:11	5/20/25	XOMA	Xoma Royalty Corp		Health	Drug	Pharmaceutical Preparations	2	4	S.d	-1,865	27.51	-68		98	D
5/21/25 12:57	5/20/25	MDCX	Medicus Pharma Ltd.	A6	Health	Drug	Pharmaceutical Preparations	1	1	S	-579	7.72	-75		3,249	I
5/20/25 17:58	5/20/25	BMRN	Biomarin Pharmaceutical Inc	DE	Health	Drug	Pharmaceutical Preparations	7	15	S.dm	-14,495	81.75	-177		1,055	D
5/20/25 16:14	5/16/25	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	10	17	S.m	-2,020	3.92	-515		4,141	D
5/19/25 18:30	5/19/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	11	S	-446	8.63	-52		412	D
5/19/25 17:54	5/16/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	32	S.dm	-6,467	15.01	-431		4,327	D
5/19/25 17:07	5/15/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	13	52	S.dm	-76,752	482.18	-159		541	D
5/19/25 16:05	5/16/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	32	S.d	-86	0.8726	-98		634	D
5/15/25 16:43	5/14/25	NGNE	Neurogene Inc.		Health	Drug	Pharmaceutical Preparations	2	2	S	-179	15.87	-11		93	D
5/14/25 21:55	5/12/25	KTTA	Pasithea Therapeutics Corp.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-1	0.8250	-1		40	D
5/13/25 19:03	5/9/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-43	53.49	-1		21	I
5/13/25 17:05	5/12/25	GNLX	Genelux Corp	DE	Health	Drug	Pharmaceutical Preparations	9	24	S.m	-2,211	2.61	-846		4,592	D
5/9/25 21:30	5/7/25	OSTX	Os Therapies Inc	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.m	-642	2.48	-259		2,770	I
5/9/25 16:15	5/8/25	FULC	Fulcrum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-4	5.93	-1		14	D
5/7/25 21:10	5/2/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	25	S.dm	-14,830	27.76	-534		541	D
5/6/25 19:06	5/2/25	PRTA	Prothena Corp Public Ltd Co	L2	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-50,840	8.10	-6,280		5,305	I
5/6/25 16:05	5/2/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-213	2.79	-76		6,125	D
5/5/25 17:34	5/2/25	DERM	Journey Medical Corp	DE	Health	Drug	Pharmaceutical Preparations	3	9	S.m	-960	5.19	-185		3,057	D
5/2/25 20:00	5/1/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	21	S.dm	-342,935	51.17	-6,702		21,664	D
5/2/25 17:04	4/30/25	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	11	16	S.dm	-116,687	125.25	-932		1,406	D
5/1/25 19:07	4/30/25	ACRV	Acrivon Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	1	2	S.m	-3,763	1.67	-2,257		3,841	I
4/30/25 16:17	3/27/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-9	1.05	-9	0	14,237	I
4/29/25 16:04	4/25/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-1,789	84.70	-21		70	D
4/15/25 17:30	3/31/25	ASMB	Assembly Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	20	S.d	-154	13.26	-12		55	D
4/15/25 16:31	4/14/25	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	9	S.d	-787	24.42	-32		144	D
4/11/25 18:20	4/9/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	17	S.dm	-11,902	16.97	-701		5,676	D
4/7/25 18:43	4/3/25	ALDX	Aldeyra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	S	-5,037	1.46	-3,452		6,259	I
4/7/25 17:18	4/3/25	IBO	Impact Biomedical Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	S	-174	0.4950	-352	-100	0	I
4/3/25 17:00	4/2/25	VERV	Verve Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	8	S.d	-115	4.42	-26		1,099	D
4/3/25 16:30	4/2/25	SYBX	Synlogic, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	S	-4	1.40	-3		49	D
4/3/25 16:27	4/2/25	INZY	Inozyme Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-60	3.68	-16		41	D
4/3/25 16:21	4/2/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	S.d	-130	2.88	-45		2,373	D
4/3/25 16:17	4/2/25	UBX	Unity Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	17	S.d	-151	1.05	-143		319	D
4/3/25 16:15	4/1/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	16	S.dm	-286,082	30.46	-9,391		12,669	D
4/2/25 17:22	3/31/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	20	S	-697	3.39	-206		7,410	D
4/2/25 17:00	3/31/25	ABBV	Abbvie Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	13	S.dm	-134,198	188.99	-710		721	D
3/26/25 17:04	3/24/25	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-845	13.99	-60		59	D
3/26/25 16:30	3/25/25	TRVI	Trevi Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	12	S.dm	-1,171	4.04	-290		917	D
3/24/25 21:00	3/21/25	ATAI	Atai Life Sciences N.V.	P7	Health	Drug	Pharmaceutical Preparations	6	9	S	-768	1.67	-458		854	D
3/21/25 17:31	3/20/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	1	1	S	-217	5.43	-40		1,354	D
3/19/25 18:11	3/17/25	SLRN	Acelyrin, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-135	3.85	-35		4,370	D
3/19/25 16:49	3/17/25	TSVT	2Seventy Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	18	S.m	-80,541	4.91	-16,393		3,133	D
3/19/25 15:31	3/18/25	NIKA	Nika Pharmaceuticals, Inc	CO	Health	Drug	Pharmaceutical Preparations	1	1	S	-500	0.2500	-2,000	0	455,590	D
3/19/25 14:48	3/18/25	OPTN	Optinose, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	19	S	-356	1.39	-256		2,283	D
3/18/25 18:45	3/17/25	VRCA	Verrica Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	10	S.dm	-1,080	4.33	-249		686	D
3/14/25 16:30	3/12/25	RPTX	Repare Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	4	12	S.m	-144	2.43	-59		599	D
3/13/25 20:00	3/12/25	SRPT	Sarepta Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	7	S.dm	-11,309	150.87	-75		143	D
3/12/25 16:01	3/10/25	PBH	Prestige Consumer Healthcare Inc.		Health	Drug	Pharmaceutical Preparations	5	9	S.d	-13,650	82.83	-165		408	D
3/11/25 20:17	3/7/25	YMAB	Y-Mabs Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	9	S.dm	-4,152	12.67	-328		913	D
3/10/25 20:07	3/10/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	4	5	S.d	-2,307	28.02	-82		126	D
3/7/25 17:25	3/7/25	AUPH	Aurinia Pharmaceuticals Inc.		Health	Drug	Pharmaceutical Preparations	13	14	S.dm	-6,252	7.85	-796		4,322	D
3/6/25 21:30	3/4/25	INVA	Innoviva, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-28,395	17.55	-1,618		5,659	I
3/6/25 21:08	3/4/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-1,486	3.67	-405		3,527	D
3/6/25 20:30	3/14/24	APLT	Applied Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	16	S.m	-8,186	5.17	-1,583		10,590	D
3/6/25 13:57	3/4/25	PFE	Pfizer Inc	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-213	27.77	-8		12	D
3/4/25 18:09	3/3/25	AADI	Aadi Bioscience, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.dm	-466	1.79	-260		2,271	D
3/4/25 16:59	2/28/25	CARA	Cara Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	S	-15	0.8347	-18		318	D
2/28/25 18:54	11/15/24	SKYE	Skye Bioscience, Inc.	NV	Health	Drug	Pharmaceutical Preparations	6	7	S.m	-4,877	6.03	-808		20,675	D
2/28/25 16:48	2/26/25	CYCC	Cyclacel Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-5,508	0.0283	-194,629	-100	0	D
2/28/25 16:15	2/26/25	OVID	Ovid Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-5	0.5600	-9		141	D
2/27/25 16:05	2/21/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	19	S.dm	-52,348	40.98	-1,277		3,496	D
2/26/25 20:24	2/26/25	PEPG	Pepgen Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.dm	-1,045	16.59	-63		3	D
2/24/25 20:20	2/21/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	15	S.dm	-14,020	36.35	-386		2,150	D
2/21/25 19:27	2/19/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	12	S.d	-822	10.84	-76		1,151	D
2/19/25 16:23	2/15/25	MGNX	Macrogenics Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-800	15.44	-52		10	D
2/14/25 17:50	2/13/25	CMRX	Chimerix Inc	DE	Health	Drug	Pharmaceutical Preparations	5	9	S	-92	4.18	-22		1,308	D
2/6/25 20:27	2/4/25	RIGL	Rigel Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.m	-424	21.39	-20		387	D
2/6/25 20:21	2/4/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	23	S.dm	-56,911	5.54	-10,267		46,194	D
2/5/25 21:04	2/5/25	SPRO	Spero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	9	S.m	-346	0.8964	-386		3,962	D
2/5/25 18:33	2/3/25	ZNTL	Zentalis Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	5	7	S.d	-228	4.63	-49		2,781	D
2/5/25 16:02	2/4/25	ABUS	Arbutus Biopharma Corp	A1	Health	Drug	Pharmaceutical Preparations	5	5	S.d	-284	3.33	-86		1,879	D
1/31/25 18:20	1/31/25	MRVI	Maravai Lifesciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-97,696	9.80	-9,966		131,002	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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