Orbimed Advisors LLC - Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	T	TVal	Price	Qty	oc	Own	H
4/4/25 19:33	4/3/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	10,000	20.13	497		444	I
2/19/25 17:52	2/14/25	MBX	Mbx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.m	2,021	10.60	191	34	748	I
2/10/25 16:28	2/10/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	P.d	9,900	18.00	550	17	3,705	I
10/17/24 16:17	10/15/24	UPB	Upstream Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.d	14,025	17.00	825	22	4,555	I
9/17/24 20:13	9/16/24	MBX	Mbx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.d	12,000	16.00	750	24	3,812	I
8/15/24 16:51	8/13/24	SCPH	Scpharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	P	2,000	4.00	500		253	I
6/20/24 17:19	6/17/24	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	P	3,000	36.00	83	55	235	I
1/31/24 16:12	1/30/24	AVBP	Arrivent Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.d	8,000	18.00	444	42	1,514	I
1/26/24 19:14	1/25/24	ACET	Adicet Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	7,500	2.40	3,125		2,931	I
1/25/24 16:28	1/23/24	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	5,000	11.00	455	3	14,756	I
8/31/23 17:26	8/29/23	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	P	3,100	6.20	500	6	9,241	I
7/24/23 16:38	7/20/23	TSBX	Turnstone Biologics Corp.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT	P.d	5,000	12.00	417	16	3,099	I
7/19/23 16:15	7/17/23	THRX	Theseus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	1,464	3.05	480	281	651	I
6/29/23 16:46	6/27/23	ACET	Adicet Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	1,829	2.09	875	999%	962	I
6/29/23 16:42	6/27/23	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	P.m	1,002	0.8400	1,193	17	8,034	I
5/24/23 17:09	5/22/23	PRLD	Prelude Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	5,000	5.75	870	9	10,646	I
5/8/23 17:22	5/4/23	KNTE	Kinnate Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.m	4,086	2.80	1,461	331	1,903	I
5/2/23 21:34	4/28/23	KNTE	Kinnate Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.m	3,674	2.61	1,405		1,329	I
2/17/23 16:43	2/15/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	2,500	23.00	109	57	299	I
12/28/22 17:57	12/23/22	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	1,000	7.25	138	2	7,619	I
11/29/22 16:36	11/25/22	SCPH	Scpharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	P	4,002	5.25	762	16	5,560	I
11/10/22 16:44	11/8/22	CMPX	Compass Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT	P	1,290	3.21	402	2	18,791	I
11/9/22 16:25	11/7/22	THRX	Theseus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	1,000	5.21	192	1	17,234	I
9/21/22 18:00	9/19/22	THRD	Third Harmonic Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.d	5,100	17.00	300	5	5,779	I
9/16/22 16:31	9/16/22	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	5,000	10.32	484	4	14,302	I
8/18/22 17:00	8/16/22	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.d	8,930	2.42	3,690		762	I

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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