Orbimed Advisors LLC - Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	T	TVal	Price	Qty	oc	Own	H
10/27/25 17:19	10/23/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-1,520	1.52	-1,000	-17	4,975	I
9/12/25 17:09	9/10/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-900	1.80	-500	-8	5,975	I
7/1/25 21:23	6/27/25	CRVS	Corvus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	S.d	-4,892	4.16	-1,176	-14	7,165	I
6/26/25 17:10	6/24/25	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S.m	-197	0.3379	-584	-9	6,066	I
5/16/25 17:26	5/14/25	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S	-2,665	15.85	-168	-5	3,238	I
4/24/25 17:38	4/22/25	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S.m	-79	0.3342	-236	-3	6,650	I
4/17/25 18:10	4/15/25	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S.m	-50	0.3335	-149	-2	6,886	I
4/14/25 19:14	4/10/25	XTNT	Xtant Medical Holdings, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S	-30,708	0.4200	-73,115	-100	0	I
4/11/25 19:24	4/9/25	CMPX	Compass Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT	S	-5,679	1.59	-3,571	-19	15,220	I
3/26/25 19:00	3/24/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S	-310	54.11	-6	-3	187	I
3/21/25 20:00	3/19/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-2,832	54.02	-52	-22	187	I
3/12/25 21:34	3/10/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-16,966	54.31	-312	-62	194	I
1/14/25 17:17	1/10/25	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S.m	-142	0.6371	-223	-3	7,035	I
1/8/25 18:09	1/6/25	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S.m	-103	0.7026	-147	-2	7,258	I
12/26/24 16:34	12/20/24	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S	-138	0.6000	-230	-3	7,405	I
12/11/24 17:32	12/9/24	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S.m	-52	0.8348	-62	-1	7,635	I
12/6/24 19:07	12/4/24	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S.m	-77	0.7965	-97	-1	7,697	I
9/23/24 16:51	9/19/24	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S	-28	0.7100	-39	-1	7,795	I
9/18/24 18:38	9/16/24	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S.m	-147	0.7332	-200	-2	7,834	I
8/28/24 16:26	8/26/24	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S	-1,088	13.00	-84	-1	8,289	I
8/23/24 18:38	8/21/24	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-11,498	13.24	-869	-9	8,372	I
8/15/24 17:01	8/13/24	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S	-11,003	44.01	-250	-68	120	I
7/17/24 20:48	7/15/24	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	S.m	-562	10.00	-56	-7	756	I
7/2/24 16:54	6/28/24	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-2,022	4.72	-428	-15	2,407	I
5/20/24 17:00	5/16/24	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	S	-22,877	22.14	-1,033	-12	7,663	I
5/3/24 17:16	5/1/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-409	14.02	-29	-1	3,406	I
4/26/24 17:01	4/24/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S	-25	14.06	-2	0	3,436	I
4/23/24 18:38	4/19/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-913	14.12	-65	-2	3,437	I
4/18/24 17:10	4/16/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-238	14.02	-17	0	3,502	I
4/15/24 17:25	4/11/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-7,026	14.49	-485	-12	3,519	I
12/29/23 16:18	12/27/23	ALPN	Alpine Immune Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-28,672	18.54	-1,546	-85	264	I
12/20/23 18:28	12/18/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.d	-102	59.24	-2	0	1,702	D
12/15/23 18:04	12/14/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S	-24,584	56.75	-433	-66	224	I
12/14/23 17:44	12/12/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-7,902	58.88	-134	-16	728	I
11/24/23 16:38	11/22/23	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-196	2.23	-88	-1	6,475	I
10/4/23 17:36	10/2/23	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-75	9.07	-8	0	4,004	I
8/17/23 16:40	8/15/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-617	0.7500	-823	-35	1,510	I
8/2/23 17:05	7/31/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-628	3.00	-209	-9	2,106	I
7/27/23 16:28	7/25/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-114	2.92	-39	-2	2,259	I
7/17/23 16:13	7/13/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-467	2.40	-195	-8	2,286	I
5/15/23 18:07	5/11/23	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-9,938	20.58	-483	-11	3,778	I
4/21/23 17:08	4/19/23	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-1,792	9.34	-192	-6	2,836	I
4/17/23 17:28	4/13/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S.m	-128	1.87	-68	-3	2,418	I
4/12/23 18:44	4/10/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S.m	-121	1.80	-68	-3	2,464	I
4/7/23 16:42	4/5/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S.m	-222	2.16	-103	-4	2,510	I

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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