10/27/25 17:19  | 10/23/25  | PMVP | Pmv Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S | -1,520 | 1.52 | 0 | -1,000 | -17 | 4,975 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
9/12/25 17:09  | 9/10/25  | PMVP | Pmv Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S | -900 | 1.80 | 0 | -500 | -8 | 5,975 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
7/1/25 21:23  | 6/27/25  | CRVS | Corvus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S.d | -4,892 | 4.16 | 0 | -1,176 | -14 | 7,165 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/26/25 17:10  | 6/24/25  | PASG | Passage Bio, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.m | -197 | 0.3379 | 0 | -584 | -9 | 6,066 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
5/16/25 17:26  | 5/14/25  | NPCE | Neuropace Inc | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | T |  | S | -2,665 | 15.85 | 0 | -168 | -5 | 3,238 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/24/25 17:38  | 4/22/25  | PASG | Passage Bio, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.m | -79 | 0.3342 | 0 | -236 | -3 | 6,650 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/17/25 18:10  | 4/15/25  | PASG | Passage Bio, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.m | -50 | 0.3335 | 0 | -149 | -2 | 6,886 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/14/25 19:14  | 4/10/25  | XTNT | Xtant Medical Holdings, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S | -30,708 | 0.4200 | 0 | -73,115 | -100 | 0 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/11/25 19:24  | 4/9/25  | CMPX | Compass Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | DT |  | S | -5,679 | 1.59 | 0 | -3,571 | -19 | 15,220 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/26/25 19:00  | 3/24/25  | IRON | Disc Medicine, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -310 | 54.11 | 0 | -6 | -3 | 187 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/21/25 20:00  | 3/19/25  | IRON | Disc Medicine, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -2,832 | 54.02 | 0 | -52 | -22 | 187 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/12/25 21:34  | 3/10/25  | IRON | Disc Medicine, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -16,966 | 54.31 | 0 | -312 | -62 | 194 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
1/14/25 17:17  | 1/10/25  | PASG | Passage Bio, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.m | -142 | 0.6371 | 0 | -223 | -3 | 7,035 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
1/8/25 18:09  | 1/6/25  | PASG | Passage Bio, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.m | -103 | 0.7026 | 0 | -147 | -2 | 7,258 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/26/24 16:34  | 12/20/24  | PASG | Passage Bio, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S | -138 | 0.6000 | 0 | -230 | -3 | 7,405 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/11/24 17:32  | 12/9/24  | PASG | Passage Bio, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.m | -52 | 0.8348 | 0 | -62 | -1 | 7,635 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/6/24 19:07  | 12/4/24  | PASG | Passage Bio, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.m | -77 | 0.7965 | 0 | -97 | -1 | 7,697 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
9/23/24 16:51  | 9/19/24  | PASG | Passage Bio, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S | -28 | 0.7100 | 0 | -39 | -1 | 7,795 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
9/18/24 18:38  | 9/16/24  | PASG | Passage Bio, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.m | -147 | 0.7332 | 0 | -200 | -2 | 7,834 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/28/24 16:26  | 8/26/24  | SPRY | Ars Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -1,088 | 13.00 | 0 | -84 | -1 | 8,289 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/23/24 18:38  | 8/21/24  | SPRY | Ars Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -11,498 | 13.24 | 0 | -869 | -9 | 8,372 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/15/24 17:01  | 8/13/24  | KROS | Keros Therapeutics, Inc. |  | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -11,003 | 44.01 | 0 | -250 | -68 | 120 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
7/17/24 20:48  | 7/15/24  | TERN | Terns Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S.m | -562 | 10.00 | 0 | -56 | -7 | 756 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
7/2/24 16:54  | 6/28/24  | TELA | Tela Bio, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | T |  | S.m | -2,022 | 4.72 | 0 | -428 | -15 | 2,407 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
5/20/24 17:00  | 5/16/24  | ELVN | Enliven Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S | -22,877 | 22.14 | 0 | -1,033 | -12 | 7,663 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
5/3/24 17:16  | 5/1/24  | NPCE | Neuropace Inc | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | T |  | S.m | -409 | 14.02 | 0 | -29 | -1 | 3,406 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/26/24 17:01  | 4/24/24  | NPCE | Neuropace Inc | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | T |  | S | -25 | 14.06 | 0 | -2 | 0 | 3,436 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/23/24 18:38  | 4/19/24  | NPCE | Neuropace Inc | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | T |  | S.m | -913 | 14.12 | 0 | -65 | -2 | 3,437 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/18/24 17:10  | 4/16/24  | NPCE | Neuropace Inc | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | T |  | S.m | -238 | 14.02 | 0 | -17 | 0 | 3,502 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/15/24 17:25  | 4/11/24  | NPCE | Neuropace Inc | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | T |  | S.m | -7,026 | 14.49 | 0 | -485 | -12 | 3,519 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/29/23 16:18  | 12/27/23  | ALPN | Alpine Immune Sciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -28,672 | 18.54 | 0 | -1,546 | -85 | 264 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/20/23 18:28  | 12/18/23  | IRON | Disc Medicine, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.d | -102 | 59.24 | 0 | -2 | 0 | 1,702 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/15/23 18:04  | 12/14/23  | IRON | Disc Medicine, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -24,584 | 56.75 | 0 | -433 | -66 | 224 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/14/23 17:44  | 12/12/23  | IRON | Disc Medicine, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -7,902 | 58.88 | 0 | -134 | -16 | 728 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
11/24/23 16:38  | 11/22/23  | PMVP | Pmv Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S | -196 | 2.23 | 0 | -88 | -1 | 6,475 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
10/4/23 17:36  | 10/2/23  | NPCE | Neuropace Inc | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | T |  | S.m | -75 | 9.07 | 0 | -8 | 0 | 4,004 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/17/23 16:40  | 8/15/23  | GLTO | Galecto, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S | -617 | 0.7500 | 0 | -823 | -35 | 1,510 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/2/23 17:05  | 7/31/23  | GLTO | Galecto, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S | -628 | 3.00 | 0 | -209 | -9 | 2,106 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
7/27/23 16:28  | 7/25/23  | GLTO | Galecto, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S | -114 | 2.92 | 0 | -39 | -2 | 2,259 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
7/17/23 16:13  | 7/13/23  | GLTO | Galecto, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S | -467 | 2.40 | 0 | -195 | -8 | 2,286 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
5/15/23 18:07  | 5/11/23  | VRNA | Verona Pharma Plc | X0 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -9,938 | 20.58 | 0 | -483 | -11 | 3,778 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/21/23 17:08  | 4/19/23  | TELA | Tela Bio, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | T |  | S.m | -1,792 | 9.34 | 0 | -192 | -6 | 2,836 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/17/23 17:28  | 4/13/23  | GLTO | Galecto, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.m | -128 | 1.87 | 0 | -68 | -3 | 2,418 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/12/23 18:44  | 4/10/23  | GLTO | Galecto, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.m | -121 | 1.80 | 0 | -68 | -3 | 2,464 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/7/23 16:42  | 4/5/23  | GLTO | Galecto, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.m | -222 | 2.16 | 0 | -103 | -4 | 2,510 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/27/22 17:38  | 12/22/22  | VRNA | Verona Pharma Plc | X0 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -136,001 | 22.15 | 0 | -6,140 | -15 | 34,086 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
11/25/22 20:13  | 11/22/22  | TCDA | Tricida, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S.m | -2,206 | 0.2145 | 0 | -10,281 | -100 | 0 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
9/14/22 16:24  | 9/12/22  | SWTX | Springworks Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S | -4,919 | 31.96 | 0 | -154 | -3 | 5,600 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/10/22 16:22  | 8/8/22  | SWTX | Springworks Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.m | -10,464 | 38.11 | 0 | -275 | -5 | 5,754 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/28/22 16:29  | 6/24/22  | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S | -7,287 | 21.31 | 0 | -342 | -45 | 415 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
5/31/22 16:36  | 5/26/22  | PMVP | Pmv Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S | -418 | 15.93 | 0 | -26 | 0 | 6,563 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/8/22 18:06  | 4/6/22  | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.m | -18,164 | 20.68 | 0 | -878 | -66 | 451 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/31/22 17:30  | 3/29/22  | PMVP | Pmv Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.m | -10,264 | 21.63 | 0 | -475 | -7 | 6,589 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
1/27/22 17:22  | 1/25/22  | ETNB | 89Bio, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.m | -592 | 8.39 | 0 | -71 | -4 | 1,829 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/30/21 21:00  | 12/29/21  | JANX | Janux Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -820 | 20.30 | 0 | -40 | -15 | 231 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/23/21 16:13  | 12/21/21  | JANX | Janux Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -2,269 | 19.00 | 0 | -119 | -34 | 235 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/17/21 17:13  | 12/16/21  | JANX | Janux Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -7,500 | 19.07 | 0 | -393 | -62 | 246 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
9/22/21 17:27  | 9/20/21  | CRVS | Corvus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S | -6,758 | 6.09 | 0 | -1,110 | -14 | 6,944 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
9/8/21 18:18  | 9/3/21  | RPTX | Repare Therapeutics Inc. | Z4 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -275 | 33.99 | 0 | -8 | -8 | 96 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
9/2/21 20:27  | 8/31/21  | RPTX | Repare Therapeutics Inc. | Z4 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -1,291 | 34.08 | 0 | -38 | -28 | 96 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/30/21 18:37  | 8/26/21  | RPTX | Repare Therapeutics Inc. | Z4 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -616 | 34.07 | 0 | -18 | -16 | 98 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/25/21 20:43  | 8/23/21  | RPTX | Repare Therapeutics Inc. | Z4 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -622 | 34.17 | 0 | -18 | -16 | 98 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/19/21 20:55  | 8/17/21  | RPTX | Repare Therapeutics Inc. | Z4 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -693 | 34.10 | 0 | -20 | -17 | 99 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
7/6/21 16:42  | 7/1/21  | SWTX | Springworks Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S | -1,357 | 85.01 | 0 | -16 | 0 | 6,028 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/30/21 21:01  | 6/28/21  | SWTX | Springworks Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S | -554 | 85.17 | 0 | -7 | 0 | 6,044 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/25/21 19:11  | 6/23/21  | SWTX | Springworks Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.m | -4,825 | 85.19 | 0 | -57 | -1 | 6,051 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/14/21 17:58  | 6/10/21  | SWTX | Springworks Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S | -2,625 | 85.09 | 0 | -31 | -1 | 6,107 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/9/21 18:26  | 6/7/21  | SWTX | Springworks Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.m | -4,102 | 85.36 | 0 | -48 | -1 | 6,138 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/31/21 17:08  | 3/29/21  | ORIC | Oric Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -2,428 | 23.48 | 0 | -103 | -4 | 2,213 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/26/21 17:51  | 3/24/21  | ORIC | Oric Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -2,754 | 24.53 | 0 | -112 | -5 | 2,316 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/23/21 17:22  | 3/19/21  | ORIC | Oric Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -863 | 26.21 | 0 | -33 | -1 | 2,428 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/18/21 21:07  | 3/16/21  | ORIC | Oric Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -1,850 | 27.95 | 0 | -66 | -3 | 2,461 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/15/21 20:55  | 3/11/21  | ORIC | Oric Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -7,276 | 30.54 | 0 | -238 | -9 | 2,527 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/3/21 18:55  | 3/1/21  | SWTX | Springworks Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S | -101,492 | 83.19 | 0 | -1,220 | -16 | 6,186 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
1/11/21 16:46  | 1/7/21  | CTIC | Cti Biopharma Corp | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S | -7,000 | 3.50 | 0 | -2,000 | -21 | 7,521 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/30/20 16:44  | 12/28/20  | ALPN | Alpine Immune Sciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S | -8,550 | 14.25 | 0 | -600 | -16 | 3,071 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/10/20 17:04  | 12/8/20  | ARPO | Aerpio Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.d | -42 | 1.96 | 0 | -21 | 0 | 5,194 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
9/23/20 17:09  | 9/21/20  | ETNB | 89Bio, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S | -7,700 | 28.00 | 0 | -275 | -13 | 1,865 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/19/20 17:24  | 8/17/20  | INSP | Inspire Medical Systems, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | D |  | S.m | -14,927 | 107.82 | 0 | -138 | -99 | 2 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/14/20 17:19  | 8/12/20  | INSP | Inspire Medical Systems, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | D |  | S.m | -10,010 | 108.58 | 0 | -92 | -40 | 140 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/11/20 18:23  | 8/7/20  | INSP | Inspire Medical Systems, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | D |  | S.m | -12,316 | 105.65 | 0 | -117 | -33 | 232 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/16/20 20:23  | 4/14/20  | ALEC | Alector, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.m | -2,010 | 23.53 | 0 | -85 | -4 | 1,907 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/9/20 17:30  | 4/7/20  | ALEC | Alector, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.m | -9,020 | 23.74 | 0 | -380 | -16 | 1,927 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
4/2/20 17:06  | 3/31/20  | ALEC | Alector, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S | -6,125 | 24.50 | 0 | -250 | -11 | 2,020 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/25/20 17:54  | 3/23/20  | ALEC | Alector, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.m | -3,425 | 24.70 | 0 | -139 | -6 | 2,080 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/10/20 17:06  | 3/6/20  | INSP | Inspire Medical Systems, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | D |  | S | -41,760 | 83.52 | 0 | -500 | -59 | 348 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/5/20 18:34  | 3/3/20  | INSP | Inspire Medical Systems, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | D |  | S | -42,123 | 84.25 | 0 | -500 | -37 | 848 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/4/20 16:17  | 3/2/20  | ALEC | Alector, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S | -48,729 | 26.00 | 0 | -1,874 | -100 | 0 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
1/13/20 16:48  | 1/9/20  | ALEC | Alector, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S | -7,410 | 19.50 | 0 | -380 | -91 | 39 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/26/19 16:54  | 12/20/19  | ALEC | Alector, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.m | -10,210 | 19.66 | 0 | -519 | -93 | 40 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/19/19 16:33  | 12/17/19  | ALEC | Alector, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S | -17,670 | 18.52 | 0 | -954 | -91 | 98 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/12/19 17:20  | 12/11/19  | TCDA | Tricida, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S | -60,000 | 40.00 | 0 | -1,500 | -13 | 9,620 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
11/29/19 11:56  | 11/26/19  | INSP | Inspire Medical Systems, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | D |  | S.m | -8,766 | 70.69 | 0 | -124 | -8 | 1,348 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/9/19 18:41  | 8/7/19  | ALEC | Alector, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S | -11,635 | 17.90 | 0 | -650 | -17 | 3,172 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
5/22/19 12:43  | 5/21/19  | PRNB | Principia Biopharma Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S | -30,250 | 30.25 | 0 | -1,000 | -38 | 1,606 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/11/19 21:30  | 3/7/19  | INSP | Inspire Medical Systems, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | D |  | S.m | -20,514 | 57.23 | 0 | -358 | -20 | 1,472 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/13/18 16:35  | 12/11/18  | INSP | Inspire Medical Systems, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | D |  | S | -23,115 | 37.60 | 0 | -615 | -100 | 0 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
9/7/18 17:05  | 8/30/18  | STDY | Steadymed Ltd. | L3 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.d | -18,938 | 4.46 | 0 | -4,246 | -100 | 0 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/21/18 19:44  | 8/13/18  | VRAY | Viewray, Inc. | DE | Health | ElcMd | Electromedical & Electrothera | Orbimed Advisors LLC | NY | T |  | S.am | -1,851 | 9.95 | 0 | -186 | -72 | 74 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/21/18 19:36  | 8/16/18  | VRAY | Viewray, Inc. | DE | Health | ElcMd | Electromedical & Electrothera | Orbimed Advisors LLC | NY | T |  | S.am | -6,712 | 9.96 | 0 | -674 | -91 | 69 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/20/18 19:19  | 8/16/18  | VRAY | Viewray, Inc. | DE | Health | ElcMd | Electromedical & Electrothera | Orbimed Advisors LLC | NY | T |  | S.m | -5,191 | 9.95 | 0 | -522 | -88 | 70 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/15/18 19:49  | 8/13/18  | VRAY | Viewray, Inc. | DE | Health | ElcMd | Electromedical & Electrothera | Orbimed Advisors LLC | NY | T |  | S.m | -1,851 | 9.95 | 0 | -186 | -71 | 75 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/10/18 19:36  | 8/8/18  | VRAY | Viewray, Inc. | DE | Health | ElcMd | Electromedical & Electrothera | Orbimed Advisors LLC | NY | T |  | S.dm | -13,646 | 9.97 | 0 | -1,369 | -95 | 76 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/7/18 18:12  | 8/3/18  | VRAY | Viewray, Inc. | DE | Health | ElcMd | Electromedical & Electrothera | Orbimed Advisors LLC | NY | T |  | S.m | -1,904 | 11.20 | 0 | -170 | -66 | 88 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/6/18 18:10  | 6/4/18  | ADAP | Adaptimmune Therapeutics Plc | X0 | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | D |  | S.m | -254 | 13.56 | 0 | -19 | 0 | 4,901 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
6/1/18 17:25  | 5/30/18  | ADAP | Adaptimmune Therapeutics Plc | X0 | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | D |  | S.m | -2,310 | 13.51 | 0 | -171 | -3 | 4,920 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
5/24/18 16:13  | 5/22/18  | RYTM | Rhythm Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | TH | See Rema | S | -596 | 30.43 | 0 | -20 | -1 | 2,750 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
5/21/18 18:15  | 5/18/18  | RYTM | Rhythm Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.m | -4,065 | 30.88 | 0 | -132 | -5 | 2,770 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
5/16/18 17:22  | 5/14/18  | ADAP | Adaptimmune Therapeutics Plc | X0 | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | D |  | S | -139 | 13.50 | 0 | -10 | 0 | 5,091 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
5/2/18 17:13  | 4/30/18  | PIRS | Pieris Pharmaceuticals, Inc. | NV | Health | Biolab | Commercial Physical & Biologi | Orbimed Advisors LLC | NY | TH | See Rema | S | -6,350 | 6.35 | 0 | -1,000 | -96 | 39 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/29/18 18:54  | 3/27/18  | ADAP | Adaptimmune Therapeutics Plc | X0 | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | D |  | S.m | -12,054 | 11.50 | 0 | -1,048 | -17 | 5,101 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/12/18 18:16  | 3/8/18  | BOLD | Audentes Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.m | -5,470 | 34.97 | 0 | -156 | -4 | 3,540 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/6/18 19:36  | 3/2/18  | GKOS | Glaukos Corp | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | D |  | S.m | -26,787 | 32.02 | 0 | -837 | -100 | 0 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/6/18 17:53  | 3/2/18  | BOLD | Audentes Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.m | -15,211 | 35.11 | 0 | -433 | -10 | 3,696 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
2/15/18 16:57  | 2/13/18  | PIRS | Pieris Pharmaceuticals, Inc. | NV | Health | Biolab | Commercial Physical & Biologi | Orbimed Advisors LLC | NY | T |  | S.d | -71 | 8.98 | 0 | -8 | -14 | 49 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
1/4/18 15:23  | 1/3/18  | PIRS | Pieris Pharmaceuticals, Inc. | NV | Health | Biolab | Commercial Physical & Biologi | Orbimed Advisors LLC | NY | T |  | S | -12,566 | 7.35 | 0 | -1,710 | -97 | 49 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/20/17 17:12  | 12/18/17  | PIRS | Pieris Pharmaceuticals, Inc. | NV | Health | Biolab | Commercial Physical & Biologi | Orbimed Advisors LLC | NY | T |  | S.d | -842 | 5.70 | 0 | -148 | -69 | 65 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
12/12/17 14:02  | 12/8/17  | LOXO | Loxo Oncology, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -20,625 | 82.50 | 0 | -250 | -21 | 941 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
11/27/17 15:30  | 11/22/17  | LOXO | Loxo Oncology, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -20,025 | 75.00 | 0 | -267 | -18 | 1,191 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
11/20/17 19:31  | 11/16/17  | LOXO | Loxo Oncology, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -20,051 | 74.26 | 0 | -270 | -16 | 1,458 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
10/5/17 15:52  | 10/3/17  | ROKA | Roka Bioscience, Inc. | DE | Electr | LabEq | Laboratory Analytical Instrum | Orbimed Advisors LLC | NY | T |  | S | -137 | 0.6800 | 0 | -202 | -100 | 0 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
10/2/17 16:07  | 9/28/17  | ROKA | Roka Bioscience, Inc. | DE | Electr | LabEq | Laboratory Analytical Instrum | Orbimed Advisors LLC | NY | T |  | S.m | -344 | 0.7240 | 0 | -475 | -100 | 2 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
9/29/17 18:06  | 9/29/17  | BOLD | Audentes Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S | -18,984 | 28.25 | 0 | -672 | -14 | 4,130 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
9/28/17 17:31  | 9/26/17  | ROKA | Roka Bioscience, Inc. | DE | Electr | LabEq | Laboratory Analytical Instrum | Orbimed Advisors LLC | NY | T |  | S.m | -126 | 0.9845 | 0 | -128 | -95 | 6 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
9/11/17 14:16  | 9/7/17  | BOLD | Audentes Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Orbimed Advisors LLC | NY | T |  | S.d | -112 | 22.35 | 0 | -5 | 0 | 4,802 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
9/5/17 21:27  | 8/31/17  | GKOS | Glaukos Corp | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | D |  | S.m | -22,473 | 38.73 | 0 | -580 | -99 | 8 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/25/17 15:30  | 8/23/17  | ROKA | Roka Bioscience, Inc. | DE | Electr | LabEq | Laboratory Analytical Instrum | Orbimed Advisors LLC | NY | T |  | S.m | -21 | 1.50 | 0 | -14 | -65 | 8 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/22/17 20:27  | 8/18/17  | ROKA | Roka Bioscience, Inc. | DE | Electr | LabEq | Laboratory Analytical Instrum | Orbimed Advisors LLC | NY | T |  | S.m | -114 | 1.52 | 0 | -75 | -91 | 8 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/17/17 17:20  | 8/15/17  | GKOS | Glaukos Corp | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | D |  | S.m | -12,326 | 37.93 | 0 | -325 | -96 | 13 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
3/14/17 19:39  | 3/10/17  | GKOS | Glaukos Corp | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | D |  | S.m | -17,339 | 45.33 | 27 | -383 | -96 | 16 | I |  | 163 | 40 | 34 | 18 | -1 | -6 | 6 | 3 | 9 | 10 |  |  |  | 
3/7/17 18:48  | 3/3/17  | GKOS | Glaukos Corp | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | D |  | S | -2,624 | 47.05 | 25 | -56 | -74 | 20 | I |  | 174 | 49 | 47 | 18 | 0 | 0 | -2 | -4 | 2 | 18 |  |  |  | 
8/12/16 20:35  | 8/10/16  | GKOS | Glaukos Corp | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | D |  | S.m | -9,869 | 33.69 | 18 | -293 | -93 | 21 | I |  | 5 | 116 | 39 | 15 | -2 | -2 | -1 | 0 | -6 | 0 | 4 | 33 |  | 
8/12/16 16:36  | 8/10/16  | LOXO | Loxo Oncology, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -12,074 | 26.96 | 3 | -448 | -21 | 1,728 | I | 99 | 22 | 50 | 11 | 13 | 4 | 2 | -4 | 3 | -2 | 3 | -13 | 64 |  | 
8/5/16 16:05  | 8/3/16  | GKOS | Glaukos Corp | DE | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | D |  | S | -13,001 | 30.59 | 18 | -425 | -95 | 23 | I |  | 3 | 98 | 41 | 16 | 6 | -5 | -2 | 2 | 1 | -7 | 0 | 32 |  | 
7/26/16 18:04  | 7/22/16  | RLYP | Relypsa Inc |  | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.m | -129,388 | 32.00 | 33 | -4,044 | -55 | 3,356 | I | 36 | -6 | 63 | 71 | 62 | 70 | 60 | 59 | 0 | 0 | 0 |  |  |  | 
12/23/15 17:06  | 12/21/15  | RLYP | Relypsa Inc |  | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.m | -13,588 | 27.18 | 33 | -500 | -6 | 7,400 | I | 8 | -17 | -20 | 22 | 30 | 11 | -1 | -3 | 3 | 3 | -31 | -55 | -37 |  | 
11/30/15 18:55  | 11/25/15  | OTIC | Otonomy, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -1,941 | 28.93 | 6 | -67 | -4 | 1,850 | I |  | 18 | 20 | 23 | 29 | 25 | 1 | 2 | 1 | 1 | 6 | -41 | -41 | -30 | 
11/24/15 20:31  | 11/20/15  | OTIC | Otonomy, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -5,735 | 28.56 | 6 | -201 | -9 | 1,917 | I |  | 21 | 16 | 30 | 48 | 24 | -2 | -2 | 1 | -7 | -1 | -53 | -50 | -38 | 
11/19/15 20:39  | 11/17/15  | OTIC | Otonomy, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -3,960 | 28.62 | 5 | -138 | -6 | 2,118 | I |  | 26 | -7 | 37 | 55 | 33 | 21 | -1 | -2 | 1 | 2 | -48 | -51 | -36 | 
10/13/15 16:01  | 10/12/15  | SIEN | Sientra, Inc. | DE | Health | Orthop | Orthopedic, Prosthetic & Surg | Orbimed Advisors LLC | NY | T |  | S | -1,722 | 5.98 | 10 | -288 | -94 | 17 | I |  |  | -64 | -76 | -74 | -70 | -41 | -16 | 2 | -11 | -41 | 31 | 28 | 42 | 
10/9/15 19:49  | 10/7/15  | SIEN | Sientra, Inc. | DE | Health | Orthop | Orthopedic, Prosthetic & Surg | Orbimed Advisors LLC | NY | T |  | S.m | -4,788 | 7.18 | 9 | -667 | -97 | 20 | I |  |  | -58 | -72 | -70 | -64 | -29 | -12 | -13 | -16 | -31 | -6 | 3 | 31 | 
10/6/15 19:34  | 10/2/15  | SIEN | Sientra, Inc. | DE | Health | Orthop | Orthopedic, Prosthetic & Surg | Orbimed Advisors LLC | NY | T |  | S.m | -1,681 | 8.71 | 8 | -193 | -88 | 26 | I |  |  | -54 | -67 | -63 | -65 | -16 | -19 | -6 | -20 | -42 | -12 | -8 | 18 | 
10/1/15 17:55  | 9/29/15  | SIEN | Sientra, Inc. | DE | Health | Orthop | Orthopedic, Prosthetic & Surg | Orbimed Advisors LLC | NY | T |  | S.m | -1,043 | 10.24 | 7 | -102 | -79 | 28 | I |  |  | -43 | -59 | -58 | -57 | -50 | 1 | 0 | -30 | -63 | -46 | -34 | -14 | 
9/28/15 21:14  | 9/24/15  | SIEN | Sientra, Inc. | DE | Health | Orthop | Orthopedic, Prosthetic & Surg | Orbimed Advisors LLC | NY | T |  | S.m | -1,597 | 10.58 | 7 | -151 | -84 | 29 | I |  |  | -45 | -60 | -60 | -56 | -58 | -50 | 0 | 3 | -59 | -41 | -31 | -18 | 
5/20/15 20:30  | 5/18/15  | RLYP | Relypsa Inc |  | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S | -49,746 | 34.13 | 14 | -1,458 | -16 | 7,400 | I |  | 58 | 74 | -2 | -2 | 10 | -1 | -5 | -2 | 3 | 1 | -29 | -47 | -59 | 
3/30/15 15:58  | 3/26/15  | ICPT | Intercept Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -45,076 | 286.75 | 33 | -157 | -12 | 1,120 | I | 687 | -11 | 19 | 94 | 41 | 11 | 3 | 10 | 1 | -7 | -9 | -13 | -42 | -58 | 
3/25/15 19:28  | 3/23/15  | ICPT | Intercept Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -57,023 | 274.41 | 33 | -208 | -14 | 1,278 | I | 621 | -27 | 8 | 71 | 35 | 0 | -5 | -7 | 8 | 8 | 9 | 2 | -30 | -52 | 
9/18/14 17:20  | 9/16/14  | RLYP | Relypsa Inc |  | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.m | -2,375 | 25.27 | 6 | -94 | -1 | 8,858 | I |  |  | -43 | 4 | 5 | -4 | 7 | -4 | -10 | -12 | -22 | 27 | 61 | -4 | 
8/27/14 21:05  | 8/25/14  | ICPT | Intercept Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -33,161 | 298.06 | 33 | -111 | -7 | 1,485 | I |  | 571 | -26 | 28 | 38 | 34 | 5 | 7 | -2 | -2 | -16 | -47 | -25 | -37 | 
8/19/14 20:22  | 8/15/14  | RLYP | Relypsa Inc |  | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S | -26,087 | 26.35 | 6 | -990 | -10 | 8,952 | I |  |  | -34 | 25 | 10 | 16 | 12 | 1 | 0 | -1 | -7 | -26 | 31 | -8 | 
8/18/14 21:07  | 8/14/14  | ICPT | Intercept Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -17,989 | 299.82 | 33 | -60 | -4 | 1,597 | I |  | 536 | -18 | 2 | 20 | 27 | 27 | 3 | 0 | 1 | -5 | -44 | -25 | -25 | 
7/1/14 18:42  | 6/27/14  | MRTX | Mirati Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.m | -2,325 | 21.66 | 2 | -107 | -8 | 1,167 | I |  |  | 19 | 5 | 18 | -4 | -4 | -10 | -4 | -15 | -6 | -8 | -4 | 58 | 
4/11/14 17:27  | 4/9/14  | ICPT | Intercept Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -26,018 | 320.00 | 33 | -81 | -5 | 1,655 | I |  | 663 | 342 | -4 | -36 | -32 | -21 | -10 | -4 | -10 | -6 | -17 | -14 | 5 | 
10/23/13 21:32  | 10/21/13  | ICPT | Intercept Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -2,506 | 62.50 | 15 | -40 | -2 | 1,735 | I |  | 164 | 52 | 12 | 5 | -27 | -12 | -12 | 8 | 4 | -8 | 514 | 410 | 321 | 
10/17/13 21:28  | 10/15/13  | ICPT | Intercept Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S | -23,537 | 62.50 | 15 | -377 | -17 | 1,775 | I |  | 216 | 90 | 19 | 28 | -12 | -13 | 0 | -7 | -8 | -18 | 362 | 300 | 261 | 
2/14/13 17:20  | 2/12/13  | SUPN | Supernus Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.m | -2,281 | 7.55 | 1 | -302 | -27 | 817 | I |  |  | -40 | -41 | 3 | 1 | -4 | 1 | -1 | -2 | -27 | -28 | -9 | 22 | 
12/19/12 21:42  | 12/17/12  | SUPN | Supernus Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.m | -2,062 | 6.92 | 4 | -298 | -8 | 3,302 | I |  |  | 44 | -35 | -41 | -33 | -5 | 3 | 1 | -1 | 2 | -22 | -10 | -4 | 
9/5/12 17:33  | 9/4/12  | AMRN | Amarin Corp Plcuk | X0 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -3,373 | 14.43 | 33 | -234 | -98 | 6 | I | 380 | 35 | 99 | 31 | -1 | 20 | 20 | 12 | 3 | -4 | -16 | -14 | -39 | -47 | 
7/30/12 19:26  | 7/27/12  | AMRN | Amarin Corp Plcuk | X0 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -5,351 | 14.61 | 33 | -366 | -31 | 834 | I | 495 | 0 | 70 | 12 | 14 | -11 | -8 | -9 | -8 | -6 | 1 | -3 | -35 | -54 | 
7/13/12 19:50  | 7/11/12  | GNOM | Complete Genomics Inc | DE | Health | Biolab | Commercial Physical & Biologi | Orbimed Advisors LLC | NY | T |  | S.m | -3,305 | 2.74 | 0 | -1,208 | -98 | 28 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
7/3/12 15:19  | 6/29/12  | ANTH | Anthera Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -942 | 0.7341 | 0 | -1,283 | -100 | 0 | I | -87 | -91 | -89 | -68 | -63 | -67 | -74 | -75 | 6 | 1 | 56 | 43 | -1 | -30 | 
6/19/12 19:31  | 6/19/12  | AMRN | Amarin Corp Plcuk | X0 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -7,968 | 12.91 | 33 | -617 | -34 | 1,200 | I | 384 | -9 | 107 | 17 | 5 | 2 | 8 | 7 | 0 | 5 | 15 | 10 | -33 | -52 | 
3/22/12 18:15  | 3/20/12  | ANTH | Anthera Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -3,837 | 2.48 | 0 | -1,549 | -55 | 1,283 | I | -60 | -55 | -38 | -54 | -64 | -56 | -20 | -10 | -6 | -6 | -19 | 1 | -48 | -65 | 
3/13/12 18:43  | 3/9/12  | PCRX | Pacira Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.m | -1,112 | 11.11 | 1 | -100 | -4 | 2,446 | I |  | 60 | 32 | 35 | 1 | 9 | 2 | 5 | 2 | 1 | -10 | 15 | 61 | 171 | 
2/29/12 21:52  | 2/27/12  | PCRX | Pacira Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.m | -465 | 11.05 | 1 | -42 | -2 | 2,546 | I |  | 58 | 26 | 53 | 33 | 9 | 7 | 3 | 0 | -2 | 5 | 2 | 66 | 117 | 
2/3/12 21:30  | 2/1/12  | PCRX | Pacira Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.m | -1,563 | 10.91 | 2 | -143 | -5 | 2,588 | I |  |  | 6 | 18 | 33 | 37 | 25 | 1 | -3 | -3 | -1 | 1 | 41 | 87 | 
12/13/11 18:37  | 12/9/11  | ANTH | Anthera Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -375 | 6.68 | 0 | -56 | -2 | 2,832 | I |  | 38 | -22 | 44 | 4 | 9 | 14 | -2 | 0 | -4 | 7 | -48 | -65 | -86 | 
11/18/11 17:57  | 11/16/11  | ANTH | Anthera Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S.m | -351 | 6.76 | 0 | -52 | -2 | 2,888 | I |  | 17 | -20 | 20 | 35 | -4 | -5 | -6 | -7 | -16 | -5 | 14 | -70 | -89 | 
11/15/11 18:29  | 11/11/11  | ANTH | Anthera Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S.m | -417 | 6.95 | 0 | -60 | -2 | 2,940 | I |  | 14 | -11 | 30 | 40 | 0 | 1 | 7 | -1 | -12 | -7 | 12 | -70 | -91 | 
11/2/11 20:04  | 10/31/11  | PCRX | Pacira Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S | -1,026 | 10.53 | 3 | -97 | -3 | 2,732 | I |  |  | -13 | -11 | -12 | -7 | -5 | -12 | -14 | -8 | -3 | 29 | 29 | 82 | 
6/10/11 18:28  | 6/8/11  | ANTH | Anthera Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S.m | -810 | 8.10 | 0 | -100 | -3 | 3,000 | I |  | 28 | 62 | 31 | 14 | 1 | 0 | 1 | 5 | 4 | -1 | -43 | -17 | -73 | 
6/6/11 06:19  | 5/16/11  | ANTH | Anthera Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S.m | -1,475 | 8.14 | 0 | -181 | -5 | 3,139 | I |  | 43 | 53 | 42 | 18 | 11 | -5 | 0 | -1 | 0 | 0 | -33 | -29 | -75 | 
6/6/11 06:16  | 5/9/11  | ANTH | Anthera Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S.m | -936 | 7.23 | 0 | -129 | -4 | 3,320 | I |  | 43 | 53 | 42 | 18 | 11 | -5 | 0 | -1 | 0 | 0 | -33 | -29 | -75 | 
5/27/11 18:58  | 5/25/11  | ANTH | Anthera Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S.m | -333 | 8.54 | 0 | -39 | -100 | 0 | I |  | 41 | 44 | 55 | 53 | 21 | 9 | 3 | -4 | -5 | 0 | -35 | -30 | -78 | 
5/18/11 19:12  | 5/16/11  | ANTH | Anthera Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S.m | -1,475 | 8.14 | 0 | -181 | -5 | 3,139 | S |  |  |  |  |  |  |  |  | 1 | 6 | 6 | -34 | -13 | -77 | 
5/11/11 20:21  | 5/9/11  | ANTH | Anthera Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S.m | -936 | 7.23 | 0 | -129 | -4 | 3,320 | S |  |  |  |  |  |  |  |  | 0 | 9 | 14 | -9 | -9 | -74 | 
5/3/11 19:26  | 4/29/11  | AMRN | Amarin Corp Plcuk | X0 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -2,137 | 16.08 | 33 | -133 | -7 | 1,817 | I | 999 | 560 | 429 | 82 | 129 | 90 | 1 | 6 | -1 | 4 | 18 | -16 | -36 | -22 | 
4/29/11 21:14  | 4/11/11  | ATHX | Athersys, Inc / New | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.m | -552 | 2.91 | 0 | -189 | -5 | 3,325 | I | 249 | -17 | 0 | -4 | 16 | -2 | -1 | -2 | 6 | 3 | 4 | -5 | -51 | -51 | 
4/26/11 20:21  | 4/20/11  | AMRN | Amarin Corp Plcuk | X0 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.a | -12,632 | 15.79 | 33 | -800 | -23 | 2,700 | I | 999 | 876 | 413 | 78 | 120 | 118 | 90 | 2 | -4 | 2 | 19 | -11 | -42 | -38 | 
4/25/11 21:46  | 4/21/11  | AMRN | Amarin Corp Plcuk | X0 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -12,500 | 16.67 | 33 | -750 | -28 | 1,950 | I | 999 | 919 | 437 | 91 | 131 | 128 | 99 | -1 | -2 | -1 | 16 | -10 | -42 | -36 | 
4/20/11 21:39  | 4/18/11  | AMRN | Amarin Corp Plcuk | X0 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -58,182 | 15.31 | 33 | -3,800 | -98 | 59 | I | 999 | 836 | 402 | 95 | 123 | 119 | 87 | 85 | 6 | -5 | 12 | -12 | -43 | -41 | 
3/28/11 21:41  | 3/24/11  | AMRN | Amarin Corp Plcuk | X0 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -1,282 | 7.41 | 16 | -173 | -3 | 6,500 | I | 993 | 412 | 155 | -6 | -9 | -3 | 3 | 6 | 0 | 2 | 115 | 96 | 45 | 56 | 
3/23/11 18:27  | 3/21/11  | AMRN | Amarin Corp Plcuk | X0 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -543 | 7.05 | 16 | -77 | -1 | 6,673 | I | 919 | 409 | 147 | -10 | -18 | -8 | -4 | -1 | 5 | 3 | 127 | 105 | 53 | 69 | 
3/15/11 21:29  | 3/11/11  | AMRN | Amarin Corp Plcuk | X0 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -1,655 | 7.35 | 16 | -225 | -3 | 6,750 | I | 999 | 500 | 144 | 31 | -18 | -14 | -3 | 3 | 1 | -1 | 19 | 110 | 47 | 0 | 
3/7/11 21:45  | 3/3/11  | AMRN | Amarin Corp Plcuk | X0 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -574 | 7.65 | 14 | -75 | -1 | 6,975 | I | 999 | 660 | 152 | 38 | -14 | -7 | -6 | 0 | -4 | -4 | -3 | 143 | 44 | -1 | 
3/2/11 20:40  | 2/28/11  | AMRN | Amarin Corp Plcuk | X0 | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -1,884 | 7.69 | 14 | -245 | -3 | 7,050 | I | 984 | 667 | 143 | 30 | -13 | -12 | -14 | -7 | -2 | -4 | -6 | 150 | 47 | 1 | 
12/13/10 18:45  | 12/9/10  | NXTM | Nxstage Medical, Inc. | DE | Health | ElcMd | Electromedical & Electrothera | Orbimed Advisors LLC | NY | D |  | S | -53 | 22.60 | 11 | -2 | 0 | 2,690 | D | 749 | 218 | 68 | 38 | 15 | 12 | 3 | 0 | 2 | 3 | 8 | -13 | -17 | -23 | 
9/17/10 16:12  | 9/15/10  | NXTM | Nxstage Medical, Inc. | DE | Health | ElcMd | Electromedical & Electrothera | Orbimed Advisors LLC | NY | DT |  | S | -876 | 16.23 | 4 | -54 | -1 | 3,700 | I | 361 | 143 | 55 | 17 | 0 | 7 | -1 | -3 | 6 | 11 | 30 | 44 | 18 | 21 | 
9/14/10 21:45  | 9/10/10  | NXTM | Nxstage Medical, Inc. | DE | Health | ElcMd | Electromedical & Electrothera | Orbimed Advisors LLC | NY | DT |  | S.m | -6,456 | 16.56 | 5 | -390 | -9 | 3,754 | I | 377 | 149 | 52 | 21 | 3 | 8 | 3 | 3 | -1 | 6 | 26 | 40 | 22 | 9 | 
9/9/10 21:37  | 9/7/10  | NXTM | Nxstage Medical, Inc. | DE | Health | ElcMd | Electromedical & Electrothera | Orbimed Advisors LLC | NY | DT |  | S.m | -933 | 16.69 | 6 | -56 | -1 | 4,144 | I | 340 | 160 | 57 | 21 | 0 | -4 | 2 | -2 | 2 | -1 | 25 | 41 | 32 | 12 | 
8/18/10 18:19  | 8/16/10  | NXTM | Nxstage Medical, Inc. | DE | Health | ElcMd | Electromedical & Electrothera | Orbimed Advisors LLC | NY | DT |  | S.m | -8,527 | 17.05 | 10 | -500 | -11 | 4,200 | I | 378 | 207 | 100 | 30 | 21 | 5 | 5 | 5 | -2 | -10 | -3 | 30 | 30 | 12 | 
8/4/10 19:04  | 8/2/10  | NXTM | Nxstage Medical, Inc. | DE | Health | ElcMd | Electromedical & Electrothera | Orbimed Advisors LLC | NY | DT |  | S.m | -5,203 | 16.38 | 8 | -318 | -6 | 4,700 | I | 282 | 182 | 104 | 27 | 21 | 16 | -4 | 5 | 0 | -2 | 0 | 26 | 49 | 4 | 
7/29/10 18:40  | 7/27/10  | NXTM | Nxstage Medical, Inc. | DE | Health | ElcMd | Electromedical & Electrothera | Orbimed Advisors LLC | NY | DT |  | S.m | -11,823 | 16.88 | 7 | -701 | -12 | 5,018 | I | 297 | 194 | 89 | 36 | 16 | 12 | 15 | -5 | 1 | 4 | -2 | 34 | 55 | 15 | 
6/11/09 21:34  | 6/10/09  | BIOD | Biodel Inc |  | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.d | -141 | 5.24 | 0 | -27 | -2 | 1,486 | I | -70 | -65 | 124 | 31 | 6 | 18 | 17 | 8 | 5 | -8 | -20 | -9 | -31 | -27 | 
5/26/09 16:56  | 5/22/09  | ARYX | Aryx Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | T |  | S.d | -8,000 | 4.00 | 0 | -2,000 | -60 | 1,340 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
2/14/08 18:59  | 2/12/08  | BIOD | Biodel Inc |  | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | DT |  | S.d | -2,230 | 14.48 | 1 | -154 | -8 | 1,813 | I |  |  | -1 | 0 | -31 | -12 | -14 | 0 | -4 | -14 | -34 | 8 | 22 | -67 | 
6/2/06 17:23  | 5/31/06  | AVN | Avanir Pharmaceuticals | CA | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -6,159 | 9.79 | 0 | -629 | -27 | 1,706 | F |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
5/26/06 16:43  | 5/24/06  | GIVN | Given Imaging Ltd |  | Health | MdEq | Surgical & Medical Instrument | Orbimed Advisors LLC | NY | DT |  | S.d | -408 | 18.14 | 4 | -23 | -1 | 3,610 | F |  |  |  |  |  |  |  |  | -3 | -2 | -16 | 4 | 25 | 47 | 
5/18/06 11:02  | 5/16/06  | DOVP | Dov Pharmaceutical Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S | -2,658 | 3.25 | 0 | -818 | -76 | 258 | F |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
8/16/05 17:12  | 8/12/05  | DOVP | Dov Pharmaceutical Inc | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | S.m | -4,094 | 18.33 | 0 | -223 | -10 | 2,028 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  |