| 10/30/25 20:00 | 10/28/25 | JANX | Janux Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Meyer Andrew Hollman | CA | O | Chief Bu | 7 | S.d | -3,985 | 42.70 | 0 | -93 |  | 82 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 19:02 | 10/28/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Watanabe Todd | CA | DO | See Rema | 12 | S.dm | -3,539 | 16.80 | 0 | -211 |  | 1,161 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 18:40 | 8/9/24 | ANTX | An2 Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ra Capital Management, L.P. | MA | T |  | 6 | S.m | -52,285 | 10.25 | 0 | -5,101 |  | 1,911 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 18:09 | 9/9/25 | PAHC | Phibro Animal Health Corp | DE | Health | Drug | Pharmaceutical Preparations | Bendheim Jack | NJ | DOT | P,CEO | 6 | S.dm | -3,855 | 40.56 | 0 | -95 |  | 91 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 18:06 | 10/30/25 | NRIX | Nurix Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Van Houte Hans | CA | O | CFO | 13 | S.d | -1,564 | 19.08 | 0 | -82 |  | 54 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 18:02 | 10/30/25 | NRIX | Nurix Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ring Christine | CA | O | GC | 17 | S.d | -1,853 | 21.41 | 0 | -87 |  | 51 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 18:01 | 10/30/25 | NRIX | Nurix Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hansen Gwenn | CA | O | Chief Sc | 6 | S.d | -370 | 16.59 | 0 | -22 |  | 77 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 18:00 | 10/28/25 | BGMS | Bio Green Med Solution, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Yap Kim Choy | N8 | T |  | 3 | S | -316 | 2.07 | 0 | -153 |  | 385 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:47 | 10/28/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | X0 | Health | Drug | Pharmaceutical Preparations | Ragosa Mark | X0 | O | CFO | 10 | S.dm | -6,665 | 25.10 | 0 | -266 |  | 31 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:45 | 10/28/25 | TVTX | Travere Therapeutics, Inc. | CA | Health | Drug | Pharmaceutical Preparations | Dube Eric M | CA | DO | CEO | 6 | S.dm | -5,787 | 24.85 | 0 | -233 |  | 431 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:45 | 10/28/25 | TVTX | Travere Therapeutics, Inc. | CA | Health | Drug | Pharmaceutical Preparations | Heerma Peter | CA | O | Chief Co | 6 | S.dm | -414 | 21.75 | 0 | -19 |  | 128 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:44 | 10/28/25 | RYTM | Rhythm Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Shulman Joseph | MA | O | Chief Te | 13 | S.d | -7,027 | 84.66 | 0 | -83 |  | 9 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:37 | 8/21/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Mahon Paul A | MD | O | EVP,GC | 18 | S.d | -65,009 | 339.65 | 0 | -191 |  | 37 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:34 | 10/29/25 | MMM | 3M Co | DE | Health | MdEq | Surgical & Medical Instrument | Murphy Mark W. | MN | O | EVP,Chie | 1 | S.d | -3,175 | 166.55 | 0 | -19 |  | 7 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:30 | 8/26/24 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | 47 | S.dm | -121,179 | 369.15 | 0 | -328 |  | 647 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:30 | 10/28/25 | VIR | Vir Biotechnology, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Svf Endurance (Cayman) Ltd | E9 | T |  | 8 | S.m | -12,580 | 5.96 | 0 | -2,110 |  | 16,160 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:25 | 9/2/25 | CYTK | Cytokinetics Inc |  | Health | Drug | Pharmaceutical Preparations | Blum Robert I | CA | DO | P,CEO | 32 | S.d | -13,082 | 47.25 | 0 | -277 |  | 432 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:23 | 8/13/24 | UHS | Universal Health Services Inc | DE | Health | Health | General Medical & Surgical Ho | Sussman Elliot J Md Mba | FL | D |  | 3 | S.d | -1,127 | 215.56 | 0 | -5 |  | 6 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:19 | 10/28/25 | RLAY | Relay Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Rahmer Peter | MA | O | See rema | 11 | S.m | -1,318 | 5.47 | 0 | -241 |  | 434 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:15 | 10/28/25 | RLAY | Relay Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Catinazzo Thomas | MA | O | CFO | 10 | S.m | -848 | 5.13 | 0 | -165 |  | 379 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 16:12 | 10/28/25 | RLAY | Relay Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Bergstrom Donald A | MA | O | P,R,D | 10 | S.m | -851 | 4.68 | 0 | -182 |  | 616 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/30/25 08:49 | 10/28/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Jaen Juan C. | CA | O | P | 1 | S.m | -2,011 | 20.76 | 0 | -97 |  | 1,459 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 21:35 | 10/27/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Chapman Steven Leonard | TX | DO | CEO,P | 28 | S.dm | -53,661 | 145.18 | 0 | -370 |  | 372 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 21:35 | 10/27/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Brophy Michael Burkes | TX | O | CFO | 26 | S.dm | -20,333 | 159.71 | 0 | -127 |  | 110 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 21:05 | 10/27/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Sheena Jonathan | TX | DH | CO-FOUND | 28 | S.dm | -24,526 | 148.08 | 0 | -166 |  | 442 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 21:05 | 10/27/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Rabinowitz Daniel | TX | O | SEC.,GC | 17 | S.dm | -11,361 | 161.18 | 0 | -70 |  | 226 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 21:05 | 10/27/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Moshkevich Solomon | TX | O | P,CLINIC | 25 | S.dm | -12,671 | 157.37 | 0 | -81 |  | 150 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 21:05 | 10/27/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Fesko John | TX | O | P,CHIEF | 17 | S.dm | -6,620 | 155.56 | 0 | -43 |  | 157 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 19:48 | 10/28/25 | ISRG | Intuitive Surgical Inc | DE | Health | Orthop | Orthopedic, Prosthetic & Surg | Curet Myriam | CA | O | EVP,Chie | 8 | S.dm | -20,378 | 531.90 | 0 | -38 |  | 0 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 19:22 | 3/27/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Evnin Luke | MA | D |  | 2 | S.dm | -289 | 1.61 | 0 | -180 |  | 4,310 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 19:21 | 5/13/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mpm Bioventures 2014, L.P. | MA | T |  | 4 | S.dm | -6,445 | 6.76 | 0 | -953 |  | 12,932 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 19:21 | 5/13/25 | ITOS | Iteos Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Gadicke Ansbert | MA | H | Former 1 | 3 | S.dm | -8,768 | 6.68 | 0 | -1,312 |  | 10,171 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 17:19 | 10/29/25 | KYMR | Kymera Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Mainolfi Nello | MA | DO | CEO | 3 | S.d | -4,770 | 53.00 | 0 | -90 |  | 660 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 17:12 | 10/27/25 | MEDP | Medpace Holdings, Inc. | DE | Health | Biolab | Commercial Physical & Biologi | Geiger Jesse J | OH | O | P | 2 | S.dm | -32,803 | 506.00 | 0 | -65 |  | 37 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 17:10 | 10/27/25 | BBIO | Bridgebio Pharma, Inc. | DE | Health | Drug | Pharmaceutical Preparations | McCormick Frank | CA | D |  | 3 | S.d | -8,463 | 48.18 | 0 | -176 |  | 963 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 17:05 | 10/29/25 | AURA | Aura Biosciences, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Elazzouzi Amy | MA | O | SVP,Fina | 6 | S.d | -87 | 6.96 | 0 | -12 |  | 87 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 17:05 | 10/29/25 | AURA | Aura Biosciences, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | De Los Pinos Elisabet | MA | DO | See Rema | 5 | S.d | -736 | 9.27 | 0 | -79 |  | 610 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 17:04 | 8/18/25 | SER | Serina Therapeutics, Inc. | AL | Health | Drug | Pharmaceutical Preparations | Moreadith Randall | AL | O | Chief Sc | 14 | S.dm | -706 | 6.03 | 0 | -117 | -100 | 0 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:58 | 10/27/25 | MEDP | Medpace Holdings, Inc. | DE | Health | Biolab | Commercial Physical & Biologi | Ewald Stephen P | OH | O | GC,Corp. | 2 | S.d | -10,470 | 574.35 | 0 | -18 |  | 13 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:52 | 10/27/25 | MEDP | Medpace Holdings, Inc. | DE | Health | Biolab | Commercial Physical & Biologi | Burwig Susan E | OH | O | EVP,Oper | 3 | S | -9,386 | 481.34 | 0 | -20 |  | 66 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:31 | 10/27/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Shair Matthew | MA | D |  | 10 | S.m | -7,575 | 97.12 | 0 | -78 |  | 1,660 | M |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:30 | 10/27/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Adair Jason | NC | O | Chief Bu | 19 | S.dm | -1,125 | 21.66 | 0 | -52 |  | 194 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:30 | 10/27/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Boyle Dana | NC | O | Chief Ac | 5 | S | -100 | 20.56 | 0 | -5 |  | 187 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:29 | 10/22/25 | MLSS | Milestone Scientific Inc. | DE | Health | Orthop | Orthopedic, Prosthetic & Surg | Bp4 S.R.L. | L6 | T |  | 16 | S.m | -472 | 0.6415 | 0 | -735 |  | 9,655 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:24 | 10/27/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hattersley Gary | NY | O | Chief Sc | 1 | S.d | -502 | 5.02 | 0 | -100 | -100 | 0 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:14 | 10/28/25 | GILD | Gilead Sciences, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | O'Day Daniel Patrick | CA | DO | CB,CEO | 6 | S | -6,795 | 113.25 | 0 | -60 |  | 620 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 16:02 | 10/27/25 | AGIO | Agios Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gheuens Sarah | MA | O | Chief Me | 6 | S.d | -1,140 | 38.09 | 0 | -30 |  | 62 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 13:13 | 10/27/25 | BEAM | Beam Therapeutics Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Fmr LLC | MA | TH | See Rema | 4 | S | -2,901 | 8.53 | 0 | -340 |  | 12,080 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 09:20 | 10/27/25 | IRMD | Iradimed Corp | DE | Health | MdEq | Surgical & Medical Instrument | Susi Roger E. | FL | DOT | CEO,P,CB | 7 | S | -2,548 | 72.79 | 0 | -35 |  | 4,583 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/29/25 08:54 | 12/31/24 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Goeltz II Robert C. | CA | O | CFO | 2 | S | -154 | 17.91 | 0 | -9 |  | 92 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 19:51 | 10/28/25 | VKTX | Viking Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mancini Marianna | CA | O | COO | 4 | S.d | -3,682 | 44.53 | 0 | -83 |  | 382 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 19:49 | 10/27/25 | VKTX | Viking Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Rowland Charles A Jr | CA | D |  | 1 | S.d | -2,134 | 35.57 | 0 | -60 |  | 30 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 19:48 | 10/28/25 | VKTX | Viking Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Lian Brian | CA | DO | P,CEO | 7 | S.d | -39,902 | 56.50 | 0 | -706 |  | 2,419 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 19:47 | 10/28/25 | VKTX | Viking Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Zante Greg | CA | O | CFO | 5 | S.d | -13,497 | 64.71 | 0 | -209 |  | 187 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 18:00 | 10/24/25 | BGMS | Bio Green Med Solution, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ong Yee Lung | N8 | T |  | 2 | S | -854 | 5.49 | 0 | -156 |  | 269 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 17:44 | 10/27/25 | BSX | Boston Scientific Corp | DE | Health | MdEq | Surgical & Medical Instrument | Zane Ellen M | MA | D |  | 2 | S.m | -2,723 | 102.85 | 0 | -26 |  | 35 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 17:14 | 10/24/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | Goswami Joydeep | WA | D |  | 2 | S | -48 | 16.10 | 0 | -3 |  | 47 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 17:00 | 10/24/25 | CVKD | Cadrenal Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Szot Matthew K | FL | O | CFO | 6 | S.m | -328 | 14.03 | 0 | -23 |  | 31 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 17:00 | 10/24/25 | CVKD | Cadrenal Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Pham Quang X | FL | DOT | CEO,CB | 6 | S.m | -312 | 14.04 | 0 | -22 |  | 413 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 16:30 | 10/27/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Benkowitz Michael | MD | O | P,COO | 30 | S.dm | -170,607 | 389.73 | 0 | -438 |  | 3 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 16:23 | 10/27/25 | HIMS | Hims & Hers Health, Inc. | DE | Health | Health | Offices & Clinics of Doctors | Boughton Soleil | CA | O | GC | 32 | S.dm | -12,676 | 30.59 | 0 | -414 |  | 177 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 16:15 | 10/24/25 | CDRE | Cadre Holdings, Inc. | DE | Health | Orthop | Orthopedic, Prosthetic & Surg | Williams Brad | FL | O | P | 4 | S | -1,352 | 36.15 | 0 | -37 |  | 114 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 16:15 | 10/24/25 | AVAH | Aveanna Healthcare Holdings, Inc. | DE | Health | Health | Home Health Care Services | Vigano Paul R | CT | T |  | 10 | S.m | -118,467 | 8.29 | 0 | -14,284 |  | 54,281 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 16:15 | 10/24/25 | AVAH | Aveanna Healthcare Holdings, Inc. | DE | Health | Health | Home Health Care Services | J.H. Whitney Equity Partners Vii, LLC | CT | T |  | 10 | S.m | -101,061 | 8.20 | 0 | -12,331 |  | 49,976 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 16:15 | 10/24/25 | AVAH | Aveanna Healthcare Holdings, Inc. | DE | Health | Health | Home Health Care Services | Williams Robert M Jr | CT | T |  | 10 | S.m | -118,467 | 8.29 | 0 | -14,284 |  | 54,281 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 16:10 | 10/27/25 | MRSN | Mersana Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bala Mohan | MA | O | SVP,Chie | 5 | S.dm | -37 | 1.49 | 0 | -25 |  | 69 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 15:40 | 10/24/25 | ATEC | Alphatec Holdings, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Sponsel David | CA | O | EVP,Sale | 7 | S.m | -5,594 | 12.92 | 0 | -433 |  | 735 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/28/25 11:58 | 10/27/25 | BDX | Becton Dickinson & Co | NJ | Health | MdEq | Surgical & Medical Instrument | Feld Michael | NJ | O | EVP,P,Li | 3 | S | -32 | 188.30 | 0 | 0 |  | 8 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 20:35 | 10/24/25 | EXAS | Exact Sciences Corp | DE | Health | Health | Medical Laboratories | Zanotti Katherine S | WI | D |  | 2 | S | -951 | 62.51 | 0 | -15 |  | 73 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 19:56 | 7/29/25 | CNTA | Centessa Pharmaceuticals Plc | X0 | Health | Drug | Pharmaceutical Preparations | Accardi Mario Alberto | X0 | O | P,Orexin | 5 | S.d | -852 | 18.32 | 0 | -46 |  | 216 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 18:19 | 10/24/25 | FDMT | 4D Molecular Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Bizily Scott | CA | O | GC | 10 | S.d | -337 | 16.98 | 0 | -20 |  | 8 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 17:59 | 10/27/25 | CYTK | Cytokinetics Inc |  | Health | Drug | Pharmaceutical Preparations | Wierenga Wendell | CA | D |  | 1 | S.d | -257 | 58.68 | 0 | -4 |  | 32 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 17:19 | 10/23/25 | SPRY | Ars Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D |  | 24 | S.dm | -93,657 | 1.12 | 0 | -83,556 |  | 51,281 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 16:23 | 10/24/25 | CRBP | Corbus Pharmaceuticals Holdings, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cohen Yuval | MA | DO | CEO | 3 | S.dm | -3,484 | 35.51 | 0 | -98 |  | 138 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 16:22 | 10/24/25 | CRBP | Corbus Pharmaceuticals Holdings, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Moran Sean F. | MA | O | CFO | 3 | S.dm | -1,109 | 32.80 | 0 | -34 |  | 73 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 16:15 | 10/23/25 | TNGX | Tango Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Third Rock Ventures Iv, L.P. | MA | T |  | 17 | S.m | -49,905 | 8.58 | 0 | -5,815 |  | 18,651 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 16:11 | 10/24/25 | ISRG | Intuitive Surgical Inc | DE | Health | Orthop | Orthopedic, Prosthetic & Surg | Guthart Gary S | CA | DO | Exec Cha | 5 | S.d | -63,254 | 493.89 | 0 | -128 |  | 1,266 | M |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 16:05 | 10/23/25 | TWST | Twist Bioscience Corp | DE | Health | BioPrd | Biological Products, (No Diag | Finn Patrick John | CA | O | P,COO | 25 | S | -4,138 | 38.27 | 0 | -108 |  | 274 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 15:56 | 10/24/25 | ISRG | Intuitive Surgical Inc | DE | Health | Orthop | Orthopedic, Prosthetic & Surg | Barratt Craig H | CA | D |  | 2 | S.d | -1,843 | 512.99 | 0 | -4 |  | 27 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/27/25 15:36 | 10/24/25 | ISRG | Intuitive Surgical Inc | DE | Health | Orthop | Orthopedic, Prosthetic & Surg | Rosa David J. | CA | DO | CEO (CEO | 2 | S.d | -22,619 | 551.56 | 0 | -41 |  | 234 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 21:05 | 10/24/25 | ADMA | Adma Biologics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Grossman Adam S | NJ | DO | P,CEO,,I | 11 | S.dm | -16,144 | 17.12 | 0 | -943 |  | 3,806 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 20:18 | 10/22/25 | GALT | Galectin Therapeutics Inc | NV | Health | Drug | Pharmaceutical Preparations | 10X Fund, L.P. | GA | T |  | 1 | S | -247 | 4.94 | 0 | -50 |  | 5,872 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 20:00 | 6/24/25 | KALA | Kala Bio, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Iwicki Mark T | MA | D |  | 6 | S.d | -376 | 1.78 | 0 | -211 |  | 280 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 20:00 | 10/22/25 | KALA | Kala Bio, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Reumuth Mary | MA | O | CFO | 5 | S.dm | -86 | 1.88 | 0 | -46 |  | 69 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 20:00 | 10/22/25 | KALA | Kala Bio, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bazemore Todd | MA | D |  | 5 | S.d | -106 | 1.71 | 0 | -62 |  | 88 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 20:00 | 6/24/25 | KALA | Kala Bio, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Brazzell Romulus K | MA | O | SEE REMA | 5 | S.d | -118 | 1.86 | 0 | -64 |  | 92 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 20:00 | 10/22/25 | KALA | Kala Bio, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kharabi Darius | MA | O | CHIEF BU | 5 | S.d | -78 | 2.35 | 0 | -33 |  | 68 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 18:49 | 10/23/25 | RXRX | Recursion Pharmaceuticals, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Gibson Christopher | UT | DO | CEO | 16 | S.dm | -9,734 | 5.77 | 0 | -1,687 |  | 1,273 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 18:10 | 10/22/25 | DGX | Quest Diagnostics Inc | DE | Health | Health | Medical Laboratories | Pfeiffer Gary M | NJ | D |  | 1 | S.d | -270 | 182.40 | 0 | -1 |  | 29 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 17:03 | 10/22/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | De Greef Roderick | WA | DO | P,CEO | 2 | S | -2,131 | 25.16 | 0 | -85 |  | 490 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 16:56 | 10/22/25 | RNA | Avidity Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hughes Steven George | CA | O | Chief Me | 8 | S.d | -4,330 | 41.37 | 0 | -105 |  | 82 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 16:38 | 10/22/25 | IMVT | Immunovant, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Geffner Michael | NY | O | Chief Me | 8 | S | -421 | 22.08 | 0 | -19 |  | 225 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 16:36 | 10/22/25 | IMVT | Immunovant, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Stout Jay S | NY | O | CTO | 8 | S | -390 | 21.55 | 0 | -18 |  | 209 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 16:30 | 10/23/25 | ALZN | Alzamend Neuro, Inc. | DE | Health | Drug | Pharmaceutical Preparations | McGrath Lynne Fahey | GA | D |  | 1 | S | 0 | 2.30 | 0 | 0 |  | 0 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 16:09 | 10/22/25 | AXGN | Axogen, Inc. | MN | Health | ElcMd | Electromedical & Electrothera | Burke William P. Mr. | FL | D |  | 4 | S.m | -667 | 17.34 | 0 | -38 |  | 24 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/24/25 16:01 | 10/22/25 | IRON | Disc Medicine, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ai Dmi LLC | NY | T |  | 1 | S | -59,873 | 80.47 | 0 | -744 |  | 2,814 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/23/25 18:20 | 10/21/25 | ALLO | Allogene Therapeutics, Inc. |  | Health | BioPrd | Biological Products, (No Diag | Parker Geoffrey M. | CA | O | CFO | 2 | S | -54 | 1.31 | 0 | -41 |  | 1,302 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/23/25 18:00 | 10/21/25 | BGMS | Bio Green Med Solution, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Fitters Diversified Berhad | N8 | T |  | 5 | S | -1,777 | 4.23 | 0 | -420 |  | 557 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/23/25 16:20 | 10/21/25 | APLS | Apellis Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Sullivan Timothy Eugene | MA | O | CFO | 6 | S.d | -1,695 | 28.12 | 0 | -60 |  | 203 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/23/25 09:30 | 10/20/25 | CSTL | Castle Biosciences Inc | DE | Health | Health | Medical Laboratories | Maetzold Derek J | TX | DO | P,Chief | 28 | S.dm | -5,230 | 24.31 | 0 | -215 |  | 437 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 21:05 | 10/20/25 | NTRA | Natera, Inc. | DE | Health | Health | Medical Laboratories | Rabinowitz Matthew | TX | DO | Exec CB | 11 | S.m | -56,385 | 164.12 | 0 | -344 |  | 2,565 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 19:20 | 10/20/25 | ELVN | Enliven Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Lyssikatos Joseph P | CO | O | CHIEF SC | 20 | S.m | -4,747 | 23.52 | 0 | -202 |  | 1,105 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 18:57 | 10/20/25 | RANI | Rani Therapeutics Holdings, Inc. | DE | Health | Drug | Pharmaceutical Preparations | South Cone Investments Limited Partnership | F3 | T |  | 2 | S.m | -25,853 | 2.65 | 0 | -9,752 |  | 8,302 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 17:48 | 10/22/25 | BTSG | Brightspring Health Services, Inc. | DE | Health | Health | Home Health Care Services | Kkr Phoenix Aggregator L.P. | NY | T |  | 3 | S | -749,878 | 24.89 | 0 | -30,133 |  | 79,196 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 17:39 | 8/26/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cloonan Michael | MA | DO | P,CEO | 5 | S.dm | -6,328 | 31.64 | 0 | -200 |  | 547 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 17:09 | 10/20/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | X0 | Health | Drug | Pharmaceutical Preparations | Patel Sanj K | X0 | DO | CB,CEO | 7 | S.dm | -18,285 | 31.35 | 0 | -583 |  | 222 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 17:06 | 10/20/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | X0 | Health | Drug | Pharmaceutical Preparations | Megna Michael R | X0 | O | CHIEF AC | 7 | S.dm | -4,202 | 32.56 | 0 | -129 |  | 38 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 17:02 | 9/11/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | Werner Sean | WA | O | CTO | 7 | S.m | -46 | 23.15 | 0 | -2 |  | 28 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 16:32 | 10/20/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Miller Deborah Ann | MA | O | GC | 9 | S.dm | -6,130 | 87.61 | 0 | -70 |  | 49 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 16:17 | 7/17/24 | HOLX | Hologic Inc | DE | Health | OthMd | X-Ray Apparatus & Tubes & Rel | Stamoulis Christiana | MA | D |  | 2 | S.d | -1,259 | 76.61 | 0 | -16 |  | 47 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 16:10 | 10/22/25 | BTSG | Brightspring Health Services, Inc. | DE | Health | Health | Home Health Care Services | Rousseau Jon B | KY | DO | See Rema | 2 | S.d | -18,331 | 23.91 | 0 | -767 |  | 1,554 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/22/25 16:09 | 10/22/25 | BTSG | Brightspring Health Services, Inc. | DE | Health | Health | Home Health Care Services | Nalley Lisa A | KY | O | See Rema | 2 | S.d | -889 | 25.84 | 0 | -34 |  | 131 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/21/25 21:19 | 10/21/25 | MGTX | Meiragtx Holdings Plc |  | Health | BioPrd | Biological Products, (No Diag | Giroux Richard | NY | O | CFO,COO | 4 | S | -712 | 7.42 | 0 | -96 |  | 973 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/21/25 18:18 | 9/9/25 | CYTK | Cytokinetics Inc |  | Health | Drug | Pharmaceutical Preparations | Malik Fady Ibraham | CA | O | EVP Rese | 36 | S.d | -7,471 | 50.08 | 0 | -149 |  | 141 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/21/25 18:13 | 10/17/25 | ELVN | Enliven Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kintz Samuel | CO | DO | P,CEO | 21 | S.m | -4,238 | 22.95 | 0 | -185 |  | 1,253 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/21/25 17:45 | 10/17/25 | VOR | Vor Biopharma Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Reprogrammed Interchange LLC | CA | T |  | 12 | S.m | -27,680 | 4.15 | 0 | -6,665 |  | 38,303 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/21/25 17:12 | 10/21/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Booth Bruce | MA | D |  | 7 | S.m | -40,383 | 34.24 | 0 | -1,179 |  | 4,417 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/21/25 16:56 | 10/17/25 | DNA | Ginkgo Bioworks Holdings, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Coen Steven P. | MA | O | See rema | 15 | S.d | -158 | 3.67 | 0 | -43 |  | 207 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/21/25 16:54 | 10/20/25 | CRBP | Corbus Pharmaceuticals Holdings, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Altmeyer Anne | MA | D |  | 2 | S.d | -32 | 12.98 | 0 | -2 |  | 6 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/21/25 16:05 | 10/20/25 | SLDB | Solid Biosciences Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Brooks Gabriel | MA | O | Chief Me | 3 | S.d | -49 | 5.42 | 0 | -9 |  | 34 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 20:00 | 9/12/25 | BYSI | Beyondspring Inc. |  | Health | Drug | Pharmaceutical Preparations | Decheng Capital China Life Sciences Usd Fund Iii, L.P. | CA | T |  | 17 | S.m | -2,020 | 2.36 | 0 | -855 |  | 4,488 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 19:49 | 10/17/25 | GH | Guardant Health, Inc. | DE | Health | Health | Medical Laboratories | Tariq Musa | CA | D |  | 12 | S.d | -296 | 44.18 | 0 | -7 |  | 8 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 19:48 | 8/19/25 | GH | Guardant Health, Inc. | DE | Health | Health | Medical Laboratories | Potter Myrtle S | CA | D |  | 6 | S.d | -138 | 49.99 | 0 | -3 |  | 18 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 19:13 | 10/17/25 | JNJ | Johnson & Johnson | NJ | Health | Drug | Pharmaceutical Preparations | Reed John C | NJ | O | EVP,Inno | 2 | S.d | -7,316 | 179.05 | 0 | -41 |  | 11 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 18:58 | 10/16/25 | LVTX | Lava Therapeutics Nv | P7 | Health | Drug | Pharmaceutical Preparations | Cooperatieve Gilde Healthcare IV U.A. | P7 | T |  | 3 | S.m | -5,141 | 1.48 | 0 | -3,473 |  | 5,294 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 18:00 | 10/15/25 | BGMS | Bio Green Med Solution, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kua Khai Loon | N8 | T |  | 3 | S.m | -815 | 5.03 | 0 | -162 |  | 385 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 17:35 | 8/18/25 | CRSP | Crispr Therapeutics AG | V8 | Health | BioPrd | Biological Products, (No Diag | Kulkarni Samarth | MA | DO | CEO | 10 | S.dm | -10,243 | 57.26 | 0 | -179 |  | 340 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 17:20 | 10/16/25 | XGN | Exagen Inc. | DE | Health | Health | Medical Laboratories | Aballi John | CA | DO | P,CEO | 1 | S | -376 | 11.82 | 0 | -32 |  | 755 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/20/25 16:42 | 10/17/25 | HIMS | Hims & Hers Health, Inc. | DE | Health | Health | Offices & Clinics of Doctors | Okupe Oluyemi | CA | O | CFO | 29 | S.d | -37,776 | 35.74 | 0 | -1,057 |  | 211 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 21:00 | 10/15/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Venker Eric | X0 | O | P,Immuno | 18 | S.dm | -92,095 | 13.36 | 0 | -6,893 |  | 1,654 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 20:44 | 10/17/25 | ARTV | Artiva Biotherapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Aslan Fred | CA | DO | P,CEO | 2 | S | -223 | 4.36 | 0 | -51 |  | 382 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 19:55 | 10/15/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | Casdin Partners Master Fund, L.P. | NY | T |  | 4 | S | -68,710 | 24.99 | 0 | -2,750 |  | 7,707 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 19:29 | 10/17/25 | LXEO | Lexeo Therapeutics, Inc. |  | Health | BioPrd | Biological Products, (No Diag | See Tai Sandi | NY | O | Chief De | 4 | S | -44 | 7.21 | 0 | -6 |  | 66 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 19:28 | 10/17/25 | LXEO | Lexeo Therapeutics, Inc. |  | Health | BioPrd | Biological Products, (No Diag | Robertson Jenny | NY | O | GC | 4 | S | -45 | 6.69 | 0 | -7 |  | 69 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 19:28 | 10/17/25 | LXEO | Lexeo Therapeutics, Inc. |  | Health | BioPrd | Biological Products, (No Diag | Otero Jose Manuel | NY | O | Chief Te | 2 | S | -32 | 6.49 | 0 | -5 |  | 64 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 19:26 | 10/17/25 | LXEO | Lexeo Therapeutics, Inc. |  | Health | BioPrd | Biological Products, (No Diag | Adler Eric | NY | O | Chief Me | 4 | S | -45 | 6.51 | 0 | -7 |  | 73 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 19:26 | 10/17/25 | LXEO | Lexeo Therapeutics, Inc. |  | Health | BioPrd | Biological Products, (No Diag | Townsend Richard Nolan | NY | DO | CEO | 11 | S.dm | -1,272 | 13.07 | 0 | -97 |  | 242 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 17:53 | 10/15/25 | KROS | Keros Therapeutics, Inc. |  | Health | Drug | Pharmaceutical Preparations | Pontifax Management 4 G.P. (2015) Ltd. | L3 | T |  | 1 | S | -84,975 | 17.75 | 0 | -4,787 | -100 | 11 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:41 | 10/15/25 | IRON | Disc Medicine, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bitterman Kevin | MA | D |  | 8 | S.m | -19,663 | 72.70 | 0 | -270 |  | 1,148 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:32 | 8/15/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Porter James Richard | MA | DO | P,CEO | 14 | S.d | -29,729 | 80.72 | 0 | -368 |  | 249 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:31 | 8/7/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Pelish Henry E. | MA | O | Chief Sc | 10 | S.dm | -8,707 | 88.92 | 0 | -98 |  | 66 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:31 | 10/15/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Balcom Alexandra | MA | O | CFO | 13 | S.dm | -16,560 | 85.68 | 0 | -193 |  | 62 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:28 | 10/16/25 | SDGR | Schrodinger, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dugan Margaret | NY | O | Chief Me | 2 | S | -57 | 19.35 | 0 | -3 |  | 25 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:27 | 10/15/25 | RNA | Avidity Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | McCarthy Teresa | CA | O | CHRO | 12 | S.d | -7,828 | 41.22 | 0 | -190 |  | 105 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:15 | 10/16/25 | APLS | Apellis Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Watson David O. | MA | O | GC | 12 | S | -1,743 | 26.11 | 0 | -67 |  | 228 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:10 | 10/16/25 | PRAX | Praxis Precision Medicines, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Adage Capital Management, L.P. | MA | T |  | 1 | S | -33,198 | 105.76 | 0 | -314 |  | 4,422 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 16:01 | 10/15/25 | INCY | Incyte Corp | DE | Health | Biolab | Commercial Physical & Biologi | Denton Sheila A. | DE | O | EVP,GC | 11 | S.dm | -2,052 | 75.16 | 0 | -27 |  | 33 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 15:08 | 8/13/25 | MRAI | Marpai, Inc. | DE | Health | Health | Misc Health & Allied Services | Intelligent Fanatics Capital Management LLC | PA | T |  | 1 | S.m | -271 | 1.44 | 0 | -188 |  | 3,541 | M |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 14:01 | 10/15/25 | AQST | Aquestive Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Jung Cassie | NJ | O | COO | 3 | S.d | -785 | 6.05 | 0 | -130 |  | 285 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 14:01 | 10/15/25 | AQST | Aquestive Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kraus Carl N | NJ | O | Chief Me | 1 | S | -142 | 7.00 | 0 | -20 |  | 282 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/17/25 14:00 | 10/15/25 | AQST | Aquestive Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Boyd Peter E. | NJ | O | See Rema | 3 | S | -213 | 6.07 | 0 | -35 |  | 288 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 21:35 | 10/15/25 | GILD | Gilead Sciences, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Dickinson Andrew D | CA | O | CFO | 15 | S.d | -56,571 | 97.55 | 0 | -580 |  | 173 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 21:28 | 10/15/25 | GILD | Gilead Sciences, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Mercier Johanna | CA | O | Chief Co | 10 | S.d | -11,752 | 100.14 | 0 | -117 |  | 121 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 20:16 | 10/16/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Swayze Eric | CA | O | EVP Rese | 9 | S.adm | -3,247 | 57.08 | 0 | -57 |  | 48 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 20:16 | 9/9/24 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Parshall B Lynne | CA | D |  | 10 | S.d | -3,536 | 54.40 | 0 | -65 |  | 107 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 20:16 | 10/15/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Devers Shannon L. | CA | O | EVP,Chie | 3 | S.dm | -863 | 58.77 | 0 | -15 |  | 17 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 20:15 | 10/14/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Birchler Brian | CA | O | EVP,Corp | 3 | S.dm | -1,920 | 64.04 | 0 | -30 |  | 57 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 18:18 | 5/2/25 | GRAL | Grail, Inc. |  | Health | Health | Medical Laboratories | Ragusa Robert P | CA | DO | CEO | 6 | S | -5,937 | 24.64 | 0 | -241 |  | 836 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 18:17 | 8/19/25 | GRAL | Grail, Inc. |  | Health | Health | Medical Laboratories | Ofman Joshua J. | CA | O | P | 11 | S.m | -10,924 | 42.56 | 0 | -257 |  | 562 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 17:44 | 10/16/25 | AURA | Aura Biosciences, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Plavsic Mark | MA | O | CTO | 3 | S | -167 | 7.68 | 0 | -22 |  | 209 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 16:41 | 10/15/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cohlhepp Ryan | MA | DO | P,COO | 2 | S.dm | -1,139 | 18.08 | 0 | -63 |  | 203 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 16:35 | 10/14/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | X0 | Health | Drug | Pharmaceutical Preparations | Tessari Eben | X0 | O | COO | 20 | S.dm | -18,604 | 30.86 | 0 | -603 |  | 120 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 16:30 | 10/15/25 | RAPP | Rapport Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bredt David | MA | O | Chief Sc | 8 | S | -1,020 | 14.99 | 0 | -68 |  | 469 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 16:30 | 9/4/25 | RAPP | Rapport Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ceesay Abraham | MA | DO | CEO | 3 | S | -2,357 | 26.28 | 0 | -90 |  | 722 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 16:21 | 10/7/25 | EBS | Emergent Biosolutions Inc. | DE | Health | Drug | Pharmaceutical Preparations | Glessner Coleen | MD | O | EVP,Qual | 1 | S | -306 | 10.00 | 0 | -31 |  | 144 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 16:15 | 7/9/25 | ABEO | Abeona Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Seshadri Vishwas | OH | DO | CEO | 5 | S.m | -1,105 | 5.83 | 0 | -190 |  | 1,355 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 16:13 | 8/15/25 | CNTA | Centessa Pharmaceuticals Plc | X0 | Health | Drug | Pharmaceutical Preparations | Hussain Iqbal J | X0 | O | GC | 12 | S.dm | -3,112 | 17.51 | 0 | -178 |  | 131 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/16/25 16:01 | 10/14/25 | RCKT | Rocket Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Militello John | NJ | O | See Rema | 12 | S.m | -259 | 5.57 | 0 | -46 |  | 67 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 20:12 | 10/10/25 | APLS | Apellis Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dunlop A. Sinclair | MA | D |  | 5 | S | -4,946 | 29.57 | 0 | -167 |  | 302 | M |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 19:28 | 1/7/25 | ACLX | Arcellx, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Gilson Michelle | CA | O | CFO | 10 | S.dm | -8,108 | 76.93 | 0 | -105 |  | 28 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 19:04 | 10/13/25 | MLYS | Mineralys Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Levy Adam Scott | PA | O | CFO,Secr | 7 | S.m | -2,200 | 15.92 | 0 | -138 |  | 248 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 19:04 | 10/13/25 | MLYS | Mineralys Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Congleton Jon | PA | DO | CEO | 8 | S.m | -3,160 | 14.51 | 0 | -218 |  | 976 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 19:04 | 10/15/25 | MLYS | Mineralys Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Rodman David Malcom | PA | O | Chief Me | 11 | S.d | -3,018 | 18.25 | 0 | -165 |  | 141 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 18:47 | 10/15/25 | ALKS | Alkermes Plc. |  | Health | Drug | Pharmaceutical Preparations | Hopkinson Craig C. | MA | O | EVP R,D, | 8 | S.dm | -20,144 | 32.84 | 0 | -613 |  | 99 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 18:31 | 10/10/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Swisher Daniel N Jr | CA | D |  | 14 | S.d | -1,855 | 64.53 | 0 | -29 | -100 | 0 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 18:00 | 10/13/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mazumdar Claire | MA | DO | CEO | 1 | S.dm | -467 | 18.88 | 0 | -25 |  | 310 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 17:35 | 10/14/25 | CRSP | Crispr Therapeutics AG | V8 | Health | BioPrd | Biological Products, (No Diag | Kasinger James R. | MA | O | GC,Secre | 5 | S.dm | -1,042 | 49.96 | 0 | -21 |  | 83 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 17:28 | 10/15/25 | KYMR | Kymera Therapeutics, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Gollob Jared | MA | O | Chief Me | 4 | S.dm | -5,824 | 53.91 | 0 | -108 |  | 120 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 17:09 | 10/13/25 | RVMD | Revolution Medicines, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Kelsey Stephen Michael | CA | O | See Rema | 14 | S.dm | -12,526 | 45.45 | 0 | -276 |  | 293 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 16:36 | 10/13/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Schundler Russell | NC | O | GC | 12 | S.d | -846 | 15.18 | 0 | -56 |  | 597 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 16:34 | 10/13/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Kaseta Michael | NC | O | CFO,COO | 14 | S.d | -2,376 | 17.93 | 0 | -132 |  | 412 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 16:34 | 10/13/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Moomaw Scott | NC | O | Chief Co | 12 | S.d | -2,531 | 24.31 | 0 | -104 |  | 225 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 16:33 | 10/13/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Saggar Rajeev | NC | O | Chief Me | 13 | S.d | -1,205 | 18.90 | 0 | -64 |  | 273 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 16:32 | 10/6/25 | SPRB | Spruce Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Parkman Healthcare Partners LLC | CT | T |  | 2 | S | -10 | 19.14 | 0 | -1 |  | 1 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 16:31 | 9/2/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Jeffs Roger | NC | DO | CEO | 11 | S.dm | -15,591 | 61.36 | 0 | -254 |  | 2,764 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 16:30 | 10/13/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Krepp Sarah | NC | O | Chief Hu | 3 | S | -84 | 18.33 | 0 | -5 |  | 143 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 16:15 | 9/3/25 | CGON | Cg Oncology, Inc. | DE | Health | BioPrd | Biological Products, (No Diag | Post Leonard E | CA | D |  | 14 | S.d | -613 | 28.74 | 0 | -21 |  | 30 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/15/25 13:24 | 10/15/25 | KROS | Keros Therapeutics, Inc. |  | Health | Drug | Pharmaceutical Preparations | Adar1 Capital Management, LLC | TX | T |  | 1 | S | -95,659 | 17.75 | 0 | -5,389 | -100 | 0 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 20:11 | 10/10/25 | AKRO | Akero Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cheng Andrew | CA | DO | P,CEO | 17 | S.dm | -22,662 | 41.01 | 0 | -553 |  | 716 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 19:49 | 10/13/25 | ANIP | Ani Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Cook Meredith | MN | O | SVP,GC,S | 17 | S | -390 | 67.76 | 0 | -6 |  | 82 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 17:30 | 9/11/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | Wichterman Troy | WA | O | CFO | 16 | S.m | -951 | 23.36 | 0 | -41 |  | 189 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 17:30 | 9/11/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | Berard Todd | WA | O | CMO | 18 | S.m | -814 | 23.13 | 0 | -35 |  | 136 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 17:30 | 10/9/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | Mathew Aby J. | WA | O | EVP,Chie | 20 | S.dm | -2,853 | 23.31 | 0 | -122 |  | 354 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 17:30 | 9/15/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | Aebersold Sarah | WA | O | CHRO | 20 | S.m | -805 | 24.46 | 0 | -33 |  | 80 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 17:30 | 9/11/25 | BLFS | Biolife Solutions Inc | DE | Health | ElcMd | Electromedical & Electrothera | Foster Karen A. | WA | O | Chief Qu | 16 | S.m | -324 | 23.59 | 0 | -14 |  | 196 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 16:33 | 10/10/25 | CLPT | Clearpoint Neuro, Inc. | DE | Health | MdEq | Surgical & Medical Instrument | Burnett Joseph | CA | DO | CEO,P | 2 | S | -996 | 20.88 | 0 | -48 |  | 269 | I |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 16:31 | 10/9/25 | VSTM | Verastem, Inc. | MA | Health | Drug | Pharmaceutical Preparations | Bunn Paul A. | MA | D |  | 1 | S | -75 | 9.06 | 0 | -8 |  | 8 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 16:17 | 10/10/25 | HIMS | Hims & Hers Health, Inc. | DE | Health | Health | Offices & Clinics of Doctors | Chi Michael | CA | O | Chief Co | 38 | S.dm | -15,404 | 33.20 | 0 | -464 |  | 311 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 16:10 | 7/7/25 | FENC | Fennec Pharmaceuticals Inc. | A1 | Health | BioPrd | Biological Products, (No Diag | Rallis Chris A | NC | D |  | 6 | S.d | -87 | 6.66 | 0 | -13 |  | 57 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 10/14/25 16:01 | 12/16/24 | PTGX | Protagonist Therapeutics, Inc | DE | Health | Drug | Pharmaceutical Preparations | Waddill William D. | CA | D |  | 7 | S.dm | -2,535 | 53.38 | 0 | -47 |  | 54 | D |  |  |  |  |  |  |  |  |  |  |  |  |  |  |